Choline supplementation reduces oxidative stress in mouse model of allergic airway disease

European Journal of Clinical Investigation

Volumn 39, Issue 10, 2009, Pages 934-941

  Mehta, A K ^a,b   Arora, N ^a   Gaur, S N ^c   Singh, B P ^a  

^a CSIR INSTITUTE OF GENOMICS AND INTEGRATIVE BIOLOGY   (India)

^b UNIVERSITY OF PUNE   (India)

^c UNIVERSITY OF DELHI   (India)

Author keywords

Asthma; Choline; Isoprostanes; Lipid peroxidation; Nuclear factor B; Reactive oxygen species

Indexed keywords

CHOLINE; EOSINOPHIL PEROXIDASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 13; ISOPROSTANE DERIVATIVE; MALONALDEHYDE; OVALBUMIN; REACTIVE OXYGEN METABOLITE; THIOCTIC ACID; TUMOR NECROSIS FACTOR ALPHA;

ALLERGIC DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIOXIDANT ACTIVITY; ARTICLE; CELL COUNT; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFECT; DRUG MECHANISM; EOSINOPHIL; FEMALE; INFLAMMATION; LIPID PEROXIDATION; LUNG LAVAGE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RESPIRATORY TRACT DISEASE; SPLEEN CELL; SUPERNATANT; SUPPLEMENTATION; TREATMENT RESPONSE;

ADMINISTRATION, INHALATION; ANIMALS; ANTIOXIDANTS; ASTHMA; BLOTTING, WESTERN; BRONCHOALVEOLAR LAVAGE FLUID; CHOLINE; DISEASE MODELS, ANIMAL; FEMALE; INFLAMMATION; MICE; MICE, INBRED BALB C; OXIDATIVE STRESS;

EID: 70349239155     PISSN: 00142972     EISSN: 13652362     Source Type: Journal    
DOI: 10.1111/j.1365-2362.2009.02190.x     Document Type: Article

References (43)

1. Elias JA, Lee CG, Zheng T, Ma B, Homer RJ, Zhu Z. New insights into the pathogenesis of asthma. J Clin Invest 2003 111 : 291 297.
2. Reynaert NL, Aesif SW, McGovern T, Brown A, Wouters EF, Irvin CG et al. Catalase overexpression fails to attenuate allergic airways disease in the mouse. J Immunol 2007 178 : 3814 3821.
3. Barnes PJ. Reactive oxygen species and airway inflammation. Free Radic Biol Med 1990 9 : 235 243.
4. Nadeem A, Chhabra SK, Masood A, Raj HG. Increased oxidative stress and altered levels of antioxidants in asthma. J Allergy Clin Immunol 2003 111 : 72 8.
5. Crapo JD. Oxidative stress as an initiator of cytokine release and cell damage. Eur Respir J 2003 44 : 4s 6s.
6. Kelly FJ, Mudway I, Blomberg A, Frew A, Sandström T. Altered lung antioxidant status in patients with mild asthma. Lancet 1999 354 : 482 483.
7. Bowler RP, Crapo JD. Oxidative stress in allergic respiratory diseases. J Allergy Clin Immunol 2002 110 : 349 356.
8. Caramori G, Papi A. Oxidants and asthma. Thorax 2004 59 : 170 173.
9. Hubbard R, Fogarty A. The developing story of antioxidants and asthma. Thorax 2004 59 : 8 10.
10. Rubin RN, Navon L, Cassano PA. Relationship of serum antioxidants to asthma prevalence in youth. Am J Respir Crit Care Med 2004 169 : 393 398.
11. Ganley OH, Graessle OE, Robinson HJ. Anti-inflammatory activity of components obtained from egg-yolk, peanut oil and soya-bean lecithin. J Lab Clin Med 1958 51 : 709 714.
12. Yen CL, Mar MH, Zeisel SH. Choline deficiency-induced apoptosis in PC12 cells is associated with diminished membrane phosphatidylcholine and sphingomyelin, accumulation of ceramide and diacylglycerol, and activation of a caspase. FASEB J 1999 13 : 135 142.
13. Gaur SN, Agarwal G, Gupta SK. Use of LPC antagonist, Choline, in the management of bronchial asthma. Indian J Chest Dis Allied Sci 1997 39 : 107 113.
14. Szczeklik A, Nizankowska E, Dworski R. Choline magnesium trisalicylate in patients with aspirin-induced asthma. Eur Respir J 1990 3 : 535 539.
15. Yoshida Y, Itoh N, Hayakawa M, Habuchi Y, Inoue R, Chen ZH et al. Lipid peroxidation in mice fed a choline-deficient diet as evaluated by total hydroxyoctadecadienoic acid. Nutrition 2006 22 : 303 311.
16. Grattagliano I, Vendemiale G, Caraceni P, Domenicali M, Nardo B, Cavallari A et al. Starvation impairs antioxidant defense in fatty livers of rats fed a choline-deficient diet. J Nutr 2000 130 : 2131 2136.
17. Oliveira CP, Gayotto LC, Tatai C, Della Nina BI, Lima ES, Abdalla DS et al. Vitamin C and vitamin E in prevention of nonalcoholic fatty liver disease (NAFLD) in choline deficient diet fed rats. Nutr J 2003 2 : 9.
18. Lee KS, Kim SR, Park SJ, Min KH, Lee KY, Jin SM et al. Antioxidant down-regulates interleukin-18 expression in asthma. Mol Pharmacol 2006 70 : 1184 1193.
19. Szejda P, Parce JW, Seeds MS, Bass DA. Flow cytometric quantitation of oxidative product formation by polymorphonuclear leukocytes during phagocytosis. J Immunol 1984 133 : 3303 3307.
20. Tomkinson A, Cielsewicz G, Duez C, Larson KA, Lee JJ, Gelfand EW. Temporal association between airway hyperresponsiveness and airway eosinophilia in ovalbumin-sensitized mice. Am J Respir Crit Care Med 2001 163 : 721 730. (Pubitemid 32230836)
21. Koca R, Armutcu F, Altinyazar C, Gürel A. Evaluation of lipid peroxidation, oxidant/antioxidant status, and serum nitric oxide levels in alopecia areata. Med Sci Monit 2005 11 : 296 299.
22. Castro L, Freeman BA. Reactive oxygen species in human health and disease. Nutrition 2001 17 : 163 165.
23. Ossani G, Dalghi M, Repetto M. Oxidative damage lipid peroxidation in the kidney of choline-deficient rats. Front Biosci 2007 12 : 1174 1183.
24. Cao X, Phillis JW. The free radical scavenger, alpha-lipoic acid, protects against cerebral ischemia-reperfusion injury in gerbils. Free Radic Res 1995 23 : 365 370.
25. Ametov AS, Barinov A, Dyck PJ, Hermann R, Kozlova N, Litchy WJ et al. The sensory symptoms of diabetic polyneuropathy are improved with alpha-lipoic acid: the SYDNEY trial. Diabetes Care 2003 26 : 770 776.
26. Duguet A, Iijima H, Eum SY, Hamid Q, Eidelman DH. Eosinophil peroxidase mediates protein nitration in allergic airway inflammation in mice. Am J Respir Crit Care Med 2001 164 : 1119 1126.
27. Innis SM, Davidson AG, Melynk S, James SJ. Choline-related supplements improve abnormal plasma methionine-homocysteine metabolites and glutathione status in children with cystic fibrosis. Am J Clin Nutr 2007 85 : 702 708.
28. Majano PL, Garcia-Monzon C, Garcia-Trevijano ER, Corrales FJ, Cámara J, Ortiz P et al. S-Adenosylmethionine modulates inducible nitric oxide synthase gene expression in rat liver and isolated hepatocytes. J Hepatol 2001 35 : 692 699.
29. Chawla RK, Watson WH, Eastin CE, Lee EY, Schmidt J, McClain CJ. S-Adenosylmethionine deficiency and TNF-alpha in lipopolysaccharide-induced hepatic injury. Am J Physiol 1998 275 : 125 129.
30. Song Z, Zhou Z, Chen T, Hill D, Kanga J, Barvea S et al. S-Adenosylmethionine (SAMe) protects against acute alcohol induced hepatotoxicity in mice. J Nutr Biochem 2003 14 : 591 597.
31. Grimble RF. The effects of sulfur amino acid intake on immune function in humans. J Nutr 2006 136 : 1660S 5S.
32. Sachan DS, Hongu N, Johnsen M. Decreasing oxidative stress with choline and carnitine in women. J Am Coll Nutr 2005 24 : 172 176.
33. Grattagliano I, Caraceni P, Calamita G, Ferri D, Gargano I, Palasciano G et al. Severe liver steatosis correlates with nitrosative and oxidative stress in rats. Eur J Clin Invest 2008 38 : 523 530.
34. Montuschi P, Corradi M, Ciabattoni G, Nightingale J, Kharitonov SA, Barnes PJ. Increased 8-isoprostane, a marker of oxidative stress, in exhaled condensate of asthma patients. Am J Respir Crit Care Med 1999 160 : 216 220.
35. Montuschi P, Collins JV, Ciabattoni G, Lazzeri N, Corradi M, Kharitonov SA et al. Exhaled 8-isoprostane as an in vivo biomarker of lung oxidative stress in patients with COPD and healthy smokers. Am J Respir Crit Care Med 2000 162 : 1175 1177.
36. Kawikova I, Barnes PJ, Takahashi T, Tadjkarimi S, Yacoub MH, Belvisi MG. 8-Epi-PGF2 alpha, a novel noncyclooxygenase-derived prostaglandin, constricts airways in vitro. Am J Respir Crit Care Med 1996 153 : 590 596.
37. Held HD, Uhlig S. Mechanisms of endotoxin-induced airway and pulmonary vascular hyperreactivity in mice. Am J Respir Crit Care Med 2000 162 : 1547 1552.
38. Okazawa A, Kawikova I, Cui ZH, Skoogh BE, Lötvall J. 8-Epi-PGF2 alpha induces airflow obstruction and airway plasma exudation in vivo. Am J Respir Crit Care Med 1997 155 : 436 441.
39. Mehta AK, Gaur SN, Arora N, Singh BP. Effect of choline chloride in allergen-induced mouse model of airway inflammation. Eur Respir J 2007 30 : 662 671.
40. Henderson WR Jr., Chi EY, Teo JL, Nguyen C, Kahn M. A small molecule inhibitor of redox-regulated NF-kappa B and activator protein-1 transcription blocks allergic airway inflammation in a mouse asthma model. J Immunol 2002 169 : 5294 5299.
41. Garg AK, Aggarwal BB. Reactive oxygen intermediates in TNF signaling. Mol Immunol 2002 39 : 509 517.
42. Gilmour MI. Interaction of air pollutants and pulmonary allergic responses in experimental animals. Toxicology 1995 105 : 335 342.
43. Jörres R, Nowak D, Magnussen H. The effect of ozone exposure on allergen responsiveness in subjects with asthma or rhinitis. Am J Respir Crit Care Med 1996 153 : 56 64. (Pubitemid 26026827)