Kalopanaxsaponin A exerts anti-inflammatory effects in lipopolysaccharide-stimulated microglia via inhibition of JNK and NF-κB/AP-1 pathways

Biomolecules and Therapeutics

Volumn 21, Issue 5, 2013, Pages 332-337

  Jeong, Yeon Hui ^a   Hyun, Jin Won ^b   Van Le, Tien Kim ^c   Kim, Dong Hyun ^c   Kim, Hee Sun ^a  

^a Ewha Womans University School of Medicine   (South Korea)

^b Jeju National University School of Medicine   (South Korea)

^c Kyung Hee University   (South Korea)

Author keywords

Anti inflammation; AP 1; JNK; Kalopanaxsaponin A; Microglia; NF B

Indexed keywords

CYCLOOXYGENASE 2; HEME OXYGENASE 1; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 10; KALOPANAXSAPONIN A; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE; REACTIVE OXYGEN METABOLITE; SAPONIN DERIVATIVE; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR AP 1; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BRAIN DISEASE; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; GENE EXPRESSION; KALOPANAX; KALOPANAX PICTUS; MICROGLIA; NERVE CELL STIMULATION; NONHUMAN; PROTEIN DNA BINDING; PROTEIN EXPRESSION; UPREGULATION;

EID: 84885066548     PISSN: 19769148     EISSN: 20054483     Source Type: Journal    
DOI: 10.4062/biomolther.2013.069     Document Type: Article

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