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Volumn 73, Issue 19, 2013, Pages 5905-5913

Adenomatous polyps are drivenbymicrobe-instigated focal inflammation and are controlled by IL-10-producing T cells

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL DNA; COLISTIN; GENTAMICIN; INTERLEUKIN 10; KANAMYCIN; METRONIDAZOLE; RNA 16S; TOLL LIKE RECEPTOR 4; ANTIINFECTIVE AGENT; CYTOKINE; IL10 PROTEIN, MOUSE; MESSENGER RNA;

EID: 84885064968     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-13-1511     Document Type: Article
Times cited : (302)

References (50)
  • 3
    • 0026094306 scopus 로고
    • Interleukin 10 (IL-10) inhibits cytokine synthesis by human monocytes: An autoregulatory role of IL-10 produced by monocytes
    • de Waal Malefyt R, Abrams J, Bennett B, Figdor CG, de Vries JE. Interleukin 10 (IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes. J Exp Med 1991;174:1209-20.
    • (1991) J Exp Med , vol.174 , pp. 1209-1220
    • De Waal Malefyt, R.1    Abrams, J.2    Bennett, B.3    Figdor, C.G.4    De Vries, J.E.5
  • 6
    • 0036784644 scopus 로고    scopus 로고
    • Th2 cytokine production from mast cells is directly induced by lipopolysaccharide and distinctly regulated by c-Jun. N-terminal kinase and p38 pathways
    • Masuda A, Yoshikai Y, Aiba K, Matsuguchi T. Th2 cytokine production from mast cells is directly induced by lipopolysaccharide and distinctly regulated by c-Jun. N-terminal kinase and p38 pathways. J Immunol 2002;169:3801-10.
    • (2002) J Immunol , vol.169 , pp. 3801-3810
    • Masuda, A.1    Yoshikai, Y.2    Aiba, K.3    Matsuguchi, T.4
  • 7
    • 70350464351 scopus 로고    scopus 로고
    • Interleukin 10 acts on regulatory T cells to maintain expression of the transcription factor Foxp3 and suppressive function in mice with colitis
    • Murai M, Turovskaya O, Kim G, Madan R, Karp CL, Cheroutre H, et al. Interleukin 10 acts on regulatory T cells to maintain expression of the transcription factor Foxp3 and suppressive function in mice with colitis. Nat Immunol 2009;10:1178-84.
    • (2009) Nat Immunol , vol.10 , pp. 1178-1184
    • Murai, M.1    Turovskaya, O.2    Kim, G.3    Madan, R.4    Karp, C.L.5    Cheroutre, H.6
  • 9
    • 84859416933 scopus 로고    scopus 로고
    • Regulatory T cells: Mechanisms of differentiation and function
    • Josefowicz SZ, Lu LF, Rudensky AY. Regulatory T cells: mechanisms of differentiation and function. Annu Rev Immunol 2012;30:531-64.
    • (2012) Annu Rev Immunol , vol.30 , pp. 531-564
    • Josefowicz, S.Z.1    Lu, L.F.2    Rudensky, A.Y.3
  • 11
    • 0033523607 scopus 로고    scopus 로고
    • An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation
    • Asseman C, Mauze S, Leach MW, Coffman RL, Powrie F. An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation. J Exp Med 1999;190:995-1004.
    • (1999) J Exp Med , vol.190 , pp. 995-1004
    • Asseman, C.1    Mauze, S.2    Leach, M.W.3    Coffman, R.L.4    Powrie, F.5
  • 12
    • 0037603323 scopus 로고    scopus 로고
    • Interleukin-10 in the regulation of T cell-induced colitis
    • Annacker O, Asseman C, Read S, Powrie F. Interleukin-10 in the regulation of T cell-induced colitis. J Autoimmun 2003;20:277-9.
    • (2003) J Autoimmun , vol.20 , pp. 277-279
    • Annacker, O.1    Asseman, C.2    Read, S.3    Powrie, F.4
  • 15
    • 0036224749 scopus 로고    scopus 로고
    • The APC gene in colorectal cancer
    • Fodde R. The APC gene in colorectal cancer. Eur J Cancer 2002;38:867-71.
    • (2002) Eur J Cancer , vol.38 , pp. 867-871
    • Fodde, R.1
  • 16
    • 84863989936 scopus 로고    scopus 로고
    • A bacterial driver-passenger model for colorectal cancer: Beyond the usual suspects
    • Tjalsma H, Boleij A, Marchesi JR, Dutilh BE. A bacterial driver-passenger model for colorectal cancer: beyond the usual suspects. Nat Rev Microbiol 2012;10:575-82.
    • (2012) Nat Rev Microbiol , vol.10 , pp. 575-582
    • Tjalsma, H.1    Boleij, A.2    Marchesi, J.R.3    Dutilh, B.E.4
  • 17
    • 70350576477 scopus 로고    scopus 로고
    • Microbes and colorectal cancer: Is there a relationship?
    • Uronis JM, Jobin C. Microbes and colorectal cancer: is there a relationship? Curr Oncol 2009;16:22-4.
    • (2009) Curr Oncol , vol.16 , pp. 22-24
    • Uronis, J.M.1    Jobin, C.2
  • 18
    • 84891735860 scopus 로고    scopus 로고
    • Bacteria penetrate the normally impenetrable inner colon mucus layer in both murine colitis models and patients with ulcerative colitis
    • Epub ahead of print
    • Johansson ME, Gustafsson JK, Holmen-Larsson J, Jabbar KS, Xia L, Xu H, et al. Bacteria penetrate the normally impenetrable inner colon mucus layer in both murine colitis models and patients with ulcerative colitis. Gut. 2013. [Epub ahead of print].
    • (2013) Gut
    • Johansson, M.E.1    Gustafsson, J.K.2    Holmen-Larsson, J.3    Jabbar, K.S.4    Xia, L.5    Xu, H.6
  • 19
    • 79952236009 scopus 로고    scopus 로고
    • Mast cell 5-lipoxygenase activity promotes intestinal polyposis in APCDelta468 mice
    • Cheon EC, Khazaie K, Khan MW, Strouch MJ, Krantz SB, Phillips J, et al. Mast cell 5-lipoxygenase activity promotes intestinal polyposis in APCDelta468 mice. Cancer Res 2011;71:1627-36.
    • (2011) Cancer Res , vol.71 , pp. 1627-1636
    • Cheon, E.C.1    Khazaie, K.2    Khan, M.W.3    Strouch, M.J.4    Krantz, S.B.5    Phillips, J.6
  • 21
    • 51449115025 scopus 로고    scopus 로고
    • Live imaging of cysteine-cathepsin activity reveals dynamics of focal inflammation, angiogenesis, and polyp growth
    • Gounaris E, Tung CH, Restaino C, Maehr R, Kohler R, Joyce JA, et al. Live imaging of cysteine-cathepsin activity reveals dynamics of focal inflammation, angiogenesis, and polyp growth. PLoS ONE 2008;3:e2916.
    • (2008) PLoS ONE , vol.3
    • Gounaris, E.1    Tung, C.H.2    Restaino, C.3    Maehr, R.4    Kohler, R.5    Joyce, J.A.6
  • 22
    • 0030614675 scopus 로고    scopus 로고
    • Intestinal neoplasia in the ApcMin mouse: Independence from the microbial and natural killer (beige locus) status
    • Dove WF, Clipson L, Gould KA, Luongo C, Marshall DJ, Moser AR, et al. Intestinal neoplasia in the ApcMin mouse: independence from the microbial and natural killer (beige locus) status. Cancer research 1997;57:812-4.
    • (1997) Cancer Research , vol.57 , pp. 812-814
    • Dove, W.F.1    Clipson, L.2    Gould, K.A.3    Luongo, C.4    Marshall, D.J.5    Moser, A.R.6
  • 23
    • 84862992817 scopus 로고    scopus 로고
    • Abating colon cancer polyposis by Lactobacillus acidophilus deficient in lipoteichoic acid
    • Khazaie K, Zadeh M, Khan MW, Bere P, Gounari F, Dennis K, et al. Abating colon cancer polyposis by Lactobacillus acidophilus deficient in lipoteichoic acid. Proc Natl Acad Sci U S A 2012;109:10462-7.
    • (2012) Proc Natl Acad Sci U S A , vol.109 , pp. 10462-10467
    • Khazaie, K.1    Zadeh, M.2    Khan, M.W.3    Bere, P.4    Gounari, F.5    Dennis, K.6
  • 24
    • 0032412057 scopus 로고    scopus 로고
    • Resident enteric bacteria are necessary for development of spontaneous colitis and immune system activation in interleukin-10-deficient mice
    • Sellon RK, Tonkonogy S, Schultz M, Dieleman LA, Grenther W, Balish E, et al. Resident enteric bacteria are necessary for development of spontaneous colitis and immune system activation in interleukin-10-deficient mice. Infect Immun 1998;66:5224-31.
    • (1998) Infect Immun , vol.66 , pp. 5224-5231
    • Sellon, R.K.1    Tonkonogy, S.2    Schultz, M.3    Dieleman, L.A.4    Grenther, W.5    Balish, E.6
  • 25
    • 67650462939 scopus 로고    scopus 로고
    • T-regulatory cells shift from a protective antiinflammatory to a cancer-promoting proinflammatory phenotype in polyposis
    • Gounaris E, Blatner NR, Dennis K, Magnusson F, Gurish MF, Strom TB, et al. T-regulatory cells shift from a protective antiinflammatory to a cancer-promoting proinflammatory phenotype in polyposis. Cancer Res 2009;69:5490-7.
    • (2009) Cancer Res , vol.69 , pp. 5490-5497
    • Gounaris, E.1    Blatner, N.R.2    Dennis, K.3    Magnusson, F.4    Gurish, M.F.5    Strom, T.B.6
  • 26
    • 9244237038 scopus 로고    scopus 로고
    • T cell-specific inactivation of the interleukin-10 gene in mice results in enhanced T-cell responses but normal innate responses to lipopolysaccharide or skin irritation
    • Roers A, Siewe L, Strittmatter E, Deckert M, Schluter D, Stenzel W, et al. T cell-specific inactivation of the interleukin-10 gene in mice results in enhanced T-cell responses but normal innate responses to lipopolysaccharide or skin irritation. J Exp Med 2004;200:1289-97.
    • (2004) J Exp Med , vol.200 , pp. 1289-1297
    • Roers, A.1    Siewe, L.2    Strittmatter, E.3    Deckert, M.4    Schluter, D.5    Stenzel, W.6
  • 28
    • 68649103962 scopus 로고    scopus 로고
    • 16S rRNA gene-based analysis of fecal microbiota from preterm infants with and without necrotizing enterocolitis
    • Wang Y, Hoenig JD, Malin KJ, Qamar S, Petrof EO, Sun J, et al. 16S rRNA gene-based analysis of fecal microbiota from preterm infants with and without necrotizing enterocolitis. ISME J 2009;3:944-54.
    • (2009) ISME J , vol.3 , pp. 944-954
    • Wang, Y.1    Hoenig, J.D.2    Malin, K.J.3    Qamar, S.4    Petrof, E.O.5    Sun, J.6
  • 29
    • 84863981120 scopus 로고    scopus 로고
    • Ultra-high-throughput microbial community analysis on the Illumina HiSeq and MiSeq platforms
    • Caporaso JG, Lauber CL, Walters WA, Berg-Lyons D, Huntley J, Fierer N, et al. Ultra-high-throughput microbial community analysis on the Illumina HiSeq and MiSeq platforms. ISME J 2012;6:1621-4.
    • (2012) ISME J , vol.6 , pp. 1621-1624
    • Caporaso, J.G.1    Lauber, C.L.2    Walters, W.A.3    Berg-Lyons, D.4    Huntley, J.5    Fierer, N.6
  • 30
    • 0034669960 scopus 로고    scopus 로고
    • Eosinophil major basic protein-1 does not contribute to allergen-induced airway pathologies in mouse models of asthma
    • Denzler KL, Farmer SC, Crosby JR, Borchers M, Cieslewicz G, Larson KA, et al. Eosinophil major basic protein-1 does not contribute to allergen-induced airway pathologies in mouse models of asthma. J Immunol 2000;165:5509-17.
    • (2000) J Immunol , vol.165 , pp. 5509-5517
    • Denzler, K.L.1    Farmer, S.C.2    Crosby, J.R.3    Borchers, M.4    Cieslewicz, G.5    Larson, K.A.6
  • 32
    • 0037425743 scopus 로고    scopus 로고
    • Gut flora in health and disease
    • Guarner F, Malagelada JR. Gut flora in health and disease. Lancet 2003;361:512-9.
    • (2003) Lancet , vol.361 , pp. 512-519
    • Guarner, F.1    Malagelada, J.R.2
  • 33
    • 66449101214 scopus 로고    scopus 로고
    • Enterotoxigenic Bacteroides fragilis: A rogue among symbiotes
    • Sears CL. Enterotoxigenic Bacteroides fragilis: a rogue among symbiotes. Clin Microbiol Rev 2009;22:349-69.
    • (2009) Clin Microbiol Rev , vol.22 , pp. 349-369
    • Sears, C.L.1
  • 34
    • 84862997111 scopus 로고    scopus 로고
    • Human intestinal lumen and mucosa-associated microbiota in patients with colorectal cancer
    • Chen W, Liu F, Ling Z, Tong X, Xiang C. Human intestinal lumen and mucosa-associated microbiota in patients with colorectal cancer. PLoS ONE 2012;7:e39743.
    • (2012) PLoS ONE , vol.7
    • Chen, W.1    Liu, F.2    Ling, Z.3    Tong, X.4    Xiang, C.5
  • 37
    • 41549159660 scopus 로고    scopus 로고
    • Regulatory T cell-derived interleukin-10 limits inflammation at environmental interfaces
    • Rubtsov YP, Rasmussen JP, Chi EY, Fontenot J, Castelli L, Ye X, et al. Regulatory T cell-derived interleukin-10 limits inflammation at environmental interfaces. Immunity 2008;28:546-58.
    • (2008) Immunity , vol.28 , pp. 546-558
    • Rubtsov, Y.P.1    Rasmussen, J.P.2    Chi, E.Y.3    Fontenot, J.4    Castelli, L.5    Ye, X.6
  • 38
    • 0029813545 scopus 로고    scopus 로고
    • Enterocolitis and colon cancer in interleukin-10-deficient mice are associated with aberrant cytokine production and CD4 (+) TH1-like responses
    • Berg DJ, Davidson N, Kuhn R, Muller W, Menon S, Holland G, et al. Enterocolitis and colon cancer in interleukin-10-deficient mice are associated with aberrant cytokine production and CD4 (+) TH1-like responses. J Clin Invest 1996;98:1010-20.
    • (1996) J Clin Invest , vol.98 , pp. 1010-1020
    • Berg, D.J.1    Davidson, N.2    Kuhn, R.3    Muller, W.4    Menon, S.5    Holland, G.6
  • 39
    • 0027521572 scopus 로고
    • Interleukin-10-deficient mice develop chronic enterocolitis
    • Kuhn R, Lohler J, Rennick D, Rajewsky K, Muller W. Interleukin-10- deficient mice develop chronic enterocolitis. Cell 1993;75:263-74.
    • (1993) Cell , vol.75 , pp. 263-274
    • Kuhn, R.1    Lohler, J.2    Rennick, D.3    Rajewsky, K.4    Muller, W.5
  • 40
    • 84868613705 scopus 로고    scopus 로고
    • Adenoma-linked barrier defects and microbial products drive IL-23/IL-17-mediated tumour growth
    • Grivennikov SI, Wang K, Mucida D, Stewart CA, Schnabl B, Jauch D, et al. Adenoma-linked barrier defects and microbial products drive IL-23/IL-17-mediated tumour growth. Nature 2012;491:254-8.
    • (2012) Nature , vol.491 , pp. 254-258
    • Grivennikov, S.I.1    Wang, K.2    Mucida, D.3    Stewart, C.A.4    Schnabl, B.5    Jauch, D.6
  • 41
    • 2442660296 scopus 로고    scopus 로고
    • Toll-like receptor 4 signaling by intestinal microbes influences susceptibility to food allergy
    • Bashir ME, Louie S, Shi HN, Nagler-Anderson C. Toll-like receptor 4 signaling by intestinal microbes influences susceptibility to food allergy. J Immunol 2004;172:6978-87.
    • (2004) J Immunol , vol.172 , pp. 6978-6987
    • Bashir, M.E.1    Louie, S.2    Shi, H.N.3    Nagler-Anderson, C.4
  • 42
    • 0026630561 scopus 로고
    • Transcriptional regulation of the mucosal mast cell-specific protease gene, MMCP-2, by interleukin-10 and interleukin 3
    • Ghildyal N, McNeil HP, Gurish MF, Austen KF, Stevens RL. Transcriptional regulation of the mucosal mast cell-specific protease gene, MMCP-2, by interleukin-10 and interleukin 3. J Biol Chem 1992;267:8473-7.
    • (1992) J Biol Chem , vol.267 , pp. 8473-8477
    • Ghildyal, N.1    McNeil, H.P.2    Gurish, M.F.3    Austen, K.F.4    Stevens, R.L.5
  • 43
    • 84866547629 scopus 로고    scopus 로고
    • Lymphotoxin regulates commensal responses to enable diet-induced obesity
    • Upadhyay V, Poroyko V, Kim TJ, Devkota S, Fu S, Liu D, et al. Lymphotoxin regulates commensal responses to enable diet-induced obesity. Nat Immunol 2012;13:947-53.
    • (2012) Nat Immunol , vol.13 , pp. 947-953
    • Upadhyay, V.1    Poroyko, V.2    Kim, T.J.3    Devkota, S.4    Fu, S.5    Liu, D.6
  • 45
    • 0032935617 scopus 로고    scopus 로고
    • Influences of microbiota on intestinal immune system development
    • Cebra JJ. Influences of microbiota on intestinal immune system development. Am J Clin Nutr 1999;69:1046S-51S.
    • (1999) Am J Clin Nutr , vol.69
    • Cebra, J.J.1
  • 46
    • 0035901090 scopus 로고    scopus 로고
    • Inflammation and cancer: Back to Virchow?
    • Balkwill F, Mantovani A. Inflammation and cancer: back to Virchow? Lancet 2001;357:539-45.
    • (2001) Lancet , vol.357 , pp. 539-545
    • Balkwill, F.1    Mantovani, A.2
  • 47
    • 54349104915 scopus 로고    scopus 로고
    • 'Yin and Yang' in inflammation: Duality in innate immune cell function and tumorigenesis
    • Khatami M. 'Yin and Yang' in inflammation: duality in innate immune cell function and tumorigenesis. Expert Opin Biol Ther 2008;8:1461-72.
    • (2008) Expert Opin Biol Ther , vol.8 , pp. 1461-1472
    • Khatami, M.1
  • 48
    • 84863436944 scopus 로고    scopus 로고
    • Dietary-fat-induced taurocholic acid promotes pathobiont expansion and colitis in Il10-/-mice
    • Devkota S, Wang Y, Musch MW, Leone V, Fehlner-Peach H, Nadimpalli A, et al. Dietary-fat-induced taurocholic acid promotes pathobiont expansion and colitis in Il10-/-mice. Nature 2012;487:104-8.
    • (2012) Nature , vol.487 , pp. 104-108
    • Devkota, S.1    Wang, Y.2    Musch, M.W.3    Leone, V.4    Fehlner-Peach, H.5    Nadimpalli, A.6
  • 49
    • 63149120571 scopus 로고    scopus 로고
    • Induction of persistent colitis by a human commensal, enterotoxigenic Bacteroides fragilis, in wild-type C57BL/6 mice
    • Rhee KJ, Wu S, Wu X, Huso DL, Karim B, Franco AA, et al. Induction of persistent colitis by a human commensal, enterotoxigenic Bacteroides fragilis, in wild-type C57BL/6 mice. Infect Immun 2009;77:1708-18.
    • (2009) Infect Immun , vol.77 , pp. 1708-1718
    • Rhee, K.J.1    Wu, S.2    Wu, X.3    Huso, D.L.4    Karim, B.5    Franco, A.A.6
  • 50
    • 84867745572 scopus 로고    scopus 로고
    • Increased rectal microbial richness is associated with the presence of colorectal adenomas in humans
    • Sanapareddy N, Legge RM, Jovov B, McCoy A, Burcal L, Araujo-Perez F, et al. Increased rectal microbial richness is associated with the presence of colorectal adenomas in humans. ISME J 2012;6:1858-68.
    • (2012) ISME J , vol.6 , pp. 1858-1868
    • Sanapareddy, N.1    Legge, R.M.2    Jovov, B.3    McCoy, A.4    Burcal, L.5    Araujo-Perez, F.6


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