Advanced oxidation protein products induce inflammatory response in fibroblast-like synoviocytes through NADPH oxidase -dependent activation of NF-κB

Cellular Physiology and Biochemistry

Volumn 32, Issue 4, 2013, Pages 972-985

  Zheng, Shuai ^a   Zhong, Zhao Ming ^a   Qin, Shuai ^b   Chen, Guo Xian ^a   Wu, Qian ^a   Zeng, Ji Huan ^a   Ye, Wen Bin ^a   Li, Wei ^a   Yuan, Kai ^a   Yao, Ling ^a   Chen, Jian Ting ^a  

^a SOUTHERN MEDICAL UNIVERSITY   (China)

^b ZHUHAI PEOPLE S HOSPITAL ZHUHAI HOSPITAL AFFILIATED WITH JINAN UNIVERSITY   (China)

Author keywords

Advanced oxidation protein products; Fibroblast like synoviocytes; Inflammatory response; Oxidative Stress; Reactive oxygen species

Indexed keywords

ADVANCED OXIDATION PROTEIN PRODUCT; APOCYNIN; COLLAGENASE 3; GLYCOPROTEIN GP 91; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; MESSENGER RNA; PROTEIN P47; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SN 50; STROMELYSIN; TUMOR NECROSIS FACTOR ALPHA; VASCULOTROPIN; ACETYLCYSTEINE; DIPHENYLIODONIUM SALT; I KAPPA B; OXIDOREDUCTASE INHIBITOR; PROTEIN P22; SUPEROXIDE DISMUTASE;

ANIMAL CELL; ARTICLE; CELL MEMBRANE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME DEGRADATION; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME PHOSPHORYLATION; FEMALE; FIBROBLAST; FLUORESCENCE MICROSCOPY; IMMUNOPRECIPITATION; INFLAMMATION; MICROPLATE READER; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; RAT; REAL TIME POLYMERASE CHAIN REACTION; SYNOVIOCYTE; WESTERN BLOTTING; CELL STIMULATION; CYTOPLASM; FIBROBLAST LIKE SYNOVIOCYTE; GENE EXPRESSION; IN VITRO STUDY; MOLECULAR PATHOLOGY; OXIDATIVE STRESS; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; UPREGULATION;

RATTUS;

ACETYLCYSTEINE; ADVANCED OXIDATION PROTEIN PRODUCTS; ANIMALS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; INFLAMMATION; NADPH OXIDASE; NF-KAPPA B; PROTEIN BINDING; RATS; REACTIVE OXYGEN SPECIES; REAL-TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SUPEROXIDE DISMUTASE; SYNOVIAL MEMBRANE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84885060853     PISSN: 10158987     EISSN: 14219778     Source Type: Journal    
DOI: 10.1159/000354500     Document Type: Article

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