Nm23-H1 binds to Gelsolin and inactivates its actin-severing capacity to promote tumor cell motility and metastasis

Cancer Research

Volumn 73, Issue 19, 2013, Pages 5949-5962

  Marino, Natascia ^a   Marshall, Jean Claude ^a,c   Collins, Joshua W ^a   Zhou, Ming ^b   Qian, Yongzhen ^a   Veenstra, Timothy ^b   Steeg, Patricia S ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b SAIC FREDERICK INC   (United States)

^c Catholic Health Initiatives   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; ACTIN BINDING PROTEIN; F ACTIN; GELSOLIN; IMMUNOGLOBULIN G; NUCLEOSIDE DIPHOSPHATE KINASE A; RNA;

ARTICLE; BREAST CANCER; BREAST TUMOR; CANCER CELL; CELL MOTILITY; GENE EXPRESSION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOFLUORESCENCE MICROSCOPY; IMMUNOPRECIPITATION; IN VIVO STUDY; LIVER METASTASIS; LUNG METASTASIS; LYMPH NODE; MASS SPECTROMETRY; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRECIPITATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN INTERACTION; PROTEIN PROTEIN INTERACTION; REVERSED PHASE LIQUID CHROMATOGRAPHY; RNA INTERFERENCE; SPLEEN; STRESS FIBER; SUPPRESSOR GENE; TISSUE CULTURE; TUMOR CELL;

ACTINS; ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; GELSOLIN; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; IMMUNOENZYME TECHNIQUES; IMMUNOPRECIPITATION; LIVER NEOPLASMS; LUNG NEOPLASMS; MAMMARY NEOPLASMS, ANIMAL; MICE; MICE, INBRED BALB C; MICE, NUDE; NM23 NUCLEOSIDE DIPHOSPHATE KINASES; RNA, SMALL INTERFERING; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

EID: 84885054761     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-13-0368     Document Type: Article

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