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Volumn 4, Issue 6, 2007, Pages 377-386

Concurrent down-regulation of Egr-1 and gelsolin in the majority of human breast cancer cells

Author keywords

Breast cancer; Egr 1; Gelsolin; Gene expression

Indexed keywords

EARLY GROWTH RESPONSE FACTOR 1; GELSOLIN;

EID: 38149018530     PISSN: 11096535     EISSN: 17906245     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (39)

References (46)
  • 1
    • 0031602586 scopus 로고    scopus 로고
    • Suppression of growth and transformation and induction of apoptosis by EGR-1
    • Liu C, Rangnekar VM, Adamson E and Mercola D: Suppression of growth and transformation and induction of apoptosis by EGR-1. Cancer Gene Ther 5(1): 3-28, 1998.
    • (1998) Cancer Gene Ther , vol.5 , Issue.1 , pp. 3-28
    • Liu, C.1    Rangnekar, V.M.2    Adamson, E.3    Mercola, D.4
  • 2
    • 0029812609 scopus 로고    scopus 로고
    • Luteinizing hormone deficiency and female infertility in mice lacking the transcription factor NGFI-A (Egr-1)
    • Lee SL, Sadovsky Y, Swirnoff AH, Polish JA, Goda P, Gavrilina G and Milbrandt J: Luteinizing hormone deficiency and female infertility in mice lacking the transcription factor NGFI-A (Egr-1). Science 273: 1219-1221, 1996.
    • (1996) Science , vol.273 , pp. 1219-1221
    • Lee, S.L.1    Sadovsky, Y.2    Swirnoff, A.H.3    Polish, J.A.4    Goda, P.5    Gavrilina, G.6    Milbrandt, J.7
  • 3
    • 0025773296 scopus 로고
    • Zinc finger-DNA recognition: Crystal structure of a Zif268-DNA complex at 2.1 A
    • Pavletich NP and Pabo CO: Zinc finger-DNA recognition: crystal structure of a Zif268-DNA complex at 2.1 A. Science 252(5007): 809-817, 1991.
    • (1991) Science , vol.252 , Issue.5007 , pp. 809-817
    • Pavletich, N.P.1    Pabo, C.O.2
  • 5
    • 0029161198 scopus 로고
    • Early growth response protein 1 (Egr-1): Prototype of a zinc-finger family of transcription factors
    • Gashler A and Sukhatme VP: Early growth response protein 1 (Egr-1): prototype of a zinc-finger family of transcription factors. Prog Nucleic Acid Res Mol Biol 50: 191-224, 1995.
    • (1995) Prog Nucleic Acid Res Mol Biol , vol.50 , pp. 191-224
    • Gashler, A.1    Sukhatme, V.P.2
  • 6
    • 0029996110 scopus 로고    scopus 로고
    • Egr-1-induced endothelial gene expression: A common theme in vascular injury
    • Khachigian LM, Lindner V, Williams AJ and Collins T: Egr-1-induced endothelial gene expression: a common theme in vascular injury. Science 271: 1427-1431, 1996.
    • (1996) Science , vol.271 , pp. 1427-1431
    • Khachigian, L.M.1    Lindner, V.2    Williams, A.J.3    Collins, T.4
  • 7
    • 0032563584 scopus 로고    scopus 로고
    • The transcriptional corepressor NAB2 inhibits NGF-induced differentiation of PC12 cells
    • Qu Z, Wolfraim LA, Svaren J, Ehrengruber MU, Davidson N and Milbrandt J: The transcriptional corepressor NAB2 inhibits NGF-induced differentiation of PC12 cells. J Cell Biol 142: 1075-1082, 1998.
    • (1998) J Cell Biol , vol.142 , pp. 1075-1082
    • Qu, Z.1    Wolfraim, L.A.2    Svaren, J.3    Ehrengruber, M.U.4    Davidson, N.5    Milbrandt, J.6
  • 9
    • 0028227357 scopus 로고
    • The phosphorylated forms of the transcription factor, Egr-1, bind to DNA more efficiently than non-phosphorylated
    • Huang RP and Adamson ED: The phosphorylated forms of the transcription factor, Egr-1, bind to DNA more efficiently than non-phosphorylated. Biochem Biophys Res Commun 200: 1271-1276, 1994.
    • (1994) Biochem Biophys Res Commun , vol.200 , pp. 1271-1276
    • Huang, R.P.1    Adamson, E.D.2
  • 10
    • 0031874439 scopus 로고    scopus 로고
    • Egr-1 inhibits apoptosis during the UV response: Correlation of cell survival with Egr-1 phosphorylation
    • Huang RP, Fan Y, deBelle I, Ni Z, Matheny W and Adamson ED: Egr-1 inhibits apoptosis during the UV response: correlation of cell survival with Egr-1 phosphorylation. Cell Death Differ 5: 96-106, 1998.
    • (1998) Cell Death Differ , vol.5 , pp. 96-106
    • Huang, R.P.1    Fan, Y.2    deBelle, I.3    Ni, Z.4    Matheny, W.5    Adamson, E.D.6
  • 11
    • 0027456704 scopus 로고
    • Characterization of the DNA-binding properties of the early growth response-1 (Egr-1) transcription factor: Evidence for modulation by a redox mechanism
    • Huang RP and Adamson ED: Characterization of the DNA-binding properties of the early growth response-1 (Egr-1) transcription factor: evidence for modulation by a redox mechanism. DNA Cell Biol 12: 265-273, 1993.
    • (1993) DNA Cell Biol , vol.12 , pp. 265-273
    • Huang, R.P.1    Adamson, E.D.2
  • 12
    • 0032833960 scopus 로고    scopus 로고
    • NAB2: A transcriptional brake for activated gene expression in the vessel wall?
    • Miano JM and Berk BC: NAB2: a transcriptional brake for activated gene expression in the vessel wall? Am J Pathol 155: 1009-1012, 1999.
    • (1999) Am J Pathol , vol.155 , pp. 1009-1012
    • Miano, J.M.1    Berk, B.C.2
  • 13
    • 0029092509 scopus 로고
    • Identification of NAB1, a repressor of NGFI-A- and Krox20-mediated transcription
    • Russo MW, Sevetson BR and Milbrandt J: Identification of NAB1, a repressor of NGFI-A- and Krox20-mediated transcription. Proc Natl Acad Sci USA 92: 6873-6877, 1995.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 6873-6877
    • Russo, M.W.1    Sevetson, B.R.2    Milbrandt, J.3
  • 14
    • 0028862848 scopus 로고
    • Egr-1 negatively regulates human tumor cell growth via the DNA-binding domain
    • Huang RP, Liu C, Fan Y, Mercola D and Adamson ED: Egr-1 negatively regulates human tumor cell growth via the DNA-binding domain. Cancer Res 55: 5054-5062, 1995.
    • (1995) Cancer Res , vol.55 , pp. 5054-5062
    • Huang, R.P.1    Liu, C.2    Fan, Y.3    Mercola, D.4    Adamson, E.D.5
  • 15
    • 0030837544 scopus 로고    scopus 로고
    • Decreased Egr-1 expression in human, mouse and rat mammary cells and tissues correlates with tumor formation
    • Huang RP, Fan Y, De Belle I, Niemeyer C, Gottardis MM, Mercola D and Adamson ED: Decreased Egr-1 expression in human, mouse and rat mammary cells and tissues correlates with tumor formation. Int J Cancer 72: 102-109, 1997.
    • (1997) Int J Cancer , vol.72 , pp. 102-109
    • Huang, R.P.1    Fan, Y.2    De Belle, I.3    Niemeyer, C.4    Gottardis, M.M.5    Mercola, D.6    Adamson, E.D.7
  • 16
    • 23844518684 scopus 로고    scopus 로고
    • Early growth response gene 1 (EGR1) is deleted in estrogen receptor-negative human breast carcinoma
    • Ronski K, Sanders M, Burleson JA, Moyo V, Benn P and Fang M: Early growth response gene 1 (EGR1) is deleted in estrogen receptor-negative human breast carcinoma. Cancer 104: 925-930, 2005.
    • (2005) Cancer , vol.104 , pp. 925-930
    • Ronski, K.1    Sanders, M.2    Burleson, J.A.3    Moyo, V.4    Benn, P.5    Fang, M.6
  • 19
    • 4644349497 scopus 로고    scopus 로고
    • Implication of Egr-1 in trifluoperazine-induced growth inhibition in human U87MG glioma cells
    • Shin SY, Kim CG, Hong DD, Kim JH and Lee YH: Implication of Egr-1 in trifluoperazine-induced growth inhibition in human U87MG glioma cells. Exp Mol Med 36: 380-386, 2004.
    • (2004) Exp Mol Med , vol.36 , pp. 380-386
    • Shin, S.Y.1    Kim, C.G.2    Hong, D.D.3    Kim, J.H.4    Lee, Y.H.5
  • 20
    • 0042068270 scopus 로고    scopus 로고
    • The transcription factor early growth response factor-1 (EGR-1) promotes apoptosis of neuroblastoma cells
    • Pignatelli M, Luna-Medina R, Perez-Rendon A, Santos A and Perez-Castillo A: The transcription factor early growth response factor-1 (EGR-1) promotes apoptosis of neuroblastoma cells. Biochem J 373: 739-746, 2003.
    • (2003) Biochem J , vol.373 , pp. 739-746
    • Pignatelli, M.1    Luna-Medina, R.2    Perez-Rendon, A.3    Santos, A.4    Perez-Castillo, A.5
  • 21
    • 0036232664 scopus 로고    scopus 로고
    • Transcription factor EGR-1 inhibits growth of hepatocellular carcinoma and esophageal carcinoma cell lines
    • Hao MW, Liang YR, Liu YF, Liu L, Wu MY and Yang HX: Transcription factor EGR-1 inhibits growth of hepatocellular carcinoma and esophageal carcinoma cell lines. World J Gastroenterol 8: 203-207, 2002.
    • (2002) World J Gastroenterol , vol.8 , pp. 203-207
    • Hao, M.W.1    Liang, Y.R.2    Liu, Y.F.3    Liu, L.4    Wu, M.Y.5    Yang, H.X.6
  • 22
    • 0034742273 scopus 로고    scopus 로고
    • Experimental and clinicopathologic study on the relationship between transcription factor Egr-1 and esophageal carcinoma
    • Wu MY, Chen MH, Liang YR, Meng GZ, Yang HX and Zhuang CX: Experimental and clinicopathologic study on the relationship between transcription factor Egr-1 and esophageal carcinoma. World J Gastroenterol 7: 490-495, 2001.
    • (2001) World J Gastroenterol , vol.7 , pp. 490-495
    • Wu, M.Y.1    Chen, M.H.2    Liang, Y.R.3    Meng, G.Z.4    Yang, H.X.5    Zhuang, C.X.6
  • 23
    • 0036899203 scopus 로고    scopus 로고
    • Relationship between Egr-1 gene expression and apoptosis in esophageal carcinoma and precancerous lesions
    • Wu MY, Liang YR, Wu XY and Zhuang CX: Relationship between Egr-1 gene expression and apoptosis in esophageal carcinoma and precancerous lesions. World J Gastroenterol 8: 971-975, 2002.
    • (2002) World J Gastroenterol , vol.8 , pp. 971-975
    • Wu, M.Y.1    Liang, Y.R.2    Wu, X.Y.3    Zhuang, C.X.4
  • 25
    • 23044432869 scopus 로고    scopus 로고
    • Egr-1 abrogates the block imparted by c-Myc on terminal M1 myeloid differentiation
    • Shafarenko M, Liebermann DA and Hoffman B: Egr-1 abrogates the block imparted by c-Myc on terminal M1 myeloid differentiation. Blood 106: 871-878, 2005.
    • (2005) Blood , vol.106 , pp. 871-878
    • Shafarenko, M.1    Liebermann, D.A.2    Hoffman, B.3
  • 26
    • 0032892110 scopus 로고    scopus 로고
    • Reduced connexin43 expression in high-grade human brain glioma cells
    • Huang RP, Hossain MZ, Sehgal A and Boynton AL: Reduced connexin43 expression in high-grade human brain glioma cells. J Surg Oncol 70: 21-24, 1999.
    • (1999) J Surg Oncol , vol.70 , pp. 21-24
    • Huang, R.P.1    Hossain, M.Z.2    Sehgal, A.3    Boynton, A.L.4
  • 27
    • 0037093237 scopus 로고    scopus 로고
    • Connexin 43 suppresses human glioblastoma cell growth by down-regulation of monocyte chemotactic protein 1, as discovered using protein array technology
    • Huang R, Lin Y, Wang CC, Gano J, Lin B, Shi Q, Boynton A, Burke J and Huang RP: Connexin 43 suppresses human glioblastoma cell growth by down-regulation of monocyte chemotactic protein 1, as discovered using protein array technology. Cancer Res 62: 2806-2812, 2002.
    • (2002) Cancer Res , vol.62 , pp. 2806-2812
    • Huang, R.1    Lin, Y.2    Wang, C.C.3    Gano, J.4    Lin, B.5    Shi, Q.6    Boynton, A.7    Burke, J.8    Huang, R.P.9
  • 28
    • 0036353085 scopus 로고    scopus 로고
    • Molecular mechanism of transcriptional repression of gelsolin in human breast cancer cells
    • Dong Y, Asch HL, Ying A and Asch BB: Molecular mechanism of transcriptional repression of gelsolin in human breast cancer cells. Exp Cell Res 276: 328-336, 2002.
    • (2002) Exp Cell Res , vol.276 , pp. 328-336
    • Dong, Y.1    Asch, H.L.2    Ying, A.3    Asch, B.B.4
  • 29
    • 33645969889 scopus 로고    scopus 로고
    • Ruochun Huang SLWYLCYCaR-PH: early growth response-1 suppresses human fibrosarcoma cell invasion and angiogenesis. Cancer Genomics and Proteomics 3: 71-92, 2006.
    • Ruochun Huang SLWYLCYCaR-PH: early growth response-1 suppresses human fibrosarcoma cell invasion and angiogenesis. Cancer Genomics and Proteomics 3: 71-92, 2006.
  • 30
    • 0036331135 scopus 로고    scopus 로고
    • Analysis of gene expression in Egr-1 transfected human fibrosarcoma cells
    • Liu YG, Gano J, Huang R, Lin Y, Wang SM and Huang RP: Analysis of gene expression in Egr-1 transfected human fibrosarcoma cells. J Surg Oncol 80: 190-196, 2002.
    • (2002) J Surg Oncol , vol.80 , pp. 190-196
    • Liu, Y.G.1    Gano, J.2    Huang, R.3    Lin, Y.4    Wang, S.M.5    Huang, R.P.6
  • 31
    • 0033010532 scopus 로고    scopus 로고
    • Concurrent deregulation of gelsolin and cyclin D1 in the majority of human and rodent breast cancers
    • Dong Y, Asch HL, Medina D, Ip C, Ip M, Guzman R and Asch BB: Concurrent deregulation of gelsolin and cyclin D1 in the majority of human and rodent breast cancers. Int J Cancer 81: 930-938, 1999.
    • (1999) Int J Cancer , vol.81 , pp. 930-938
    • Dong, Y.1    Asch, H.L.2    Medina, D.3    Ip, C.4    Ip, M.5    Guzman, R.6    Asch, B.B.7
  • 33
    • 0028822914 scopus 로고
    • Expression patterns of immediate early transcription factors in human small lung cancer
    • and Group MOTLCS
    • Levin WJ, Press MF, Grynor RB, Sukhatme VP, Boone TC, Slamon DJ and Group MOTLCS: Expression patterns of immediate early transcription factors in human small lung cancer. Oncogene 11: 1261-1269, 1995.
    • (1995) Oncogene , vol.11 , pp. 1261-1269
    • Levin, W.J.1    Press, M.F.2    Grynor, R.B.3    Sukhatme, V.P.4    Boone, T.C.5    Slamon, D.J.6
  • 36
    • 0035199914 scopus 로고    scopus 로고
    • The Egr-1 transcription factor directly activates PTEN during irradiation-induced signalling
    • Virolle T, Adamson ED, Baron V, Birle D, Mercola D, Mustelin T and de B, I: The Egr-1 transcription factor directly activates PTEN during irradiation-induced signalling. Nat Cell Biol 3: 1124-1128, 2001.
    • (2001) Nat Cell Biol , vol.3 , pp. 1124-1128
    • Virolle, T.1    Adamson, E.D.2    Baron, V.3    Birle, D.4    Mercola, D.5    Mustelin, T.6    de, B.I.7
  • 37
    • 17644370362 scopus 로고    scopus 로고
    • PTEN expression elicited by EGR-1 transcription factor in calyculin A-induced apoptotic cells
    • Okamura H, Yoshida K, Morimoto H and Haneji T: PTEN expression elicited by EGR-1 transcription factor in calyculin A-induced apoptotic cells. J Cell Biochem 94: 117-125, 2005.
    • (2005) J Cell Biochem , vol.94 , pp. 117-125
    • Okamura, H.1    Yoshida, K.2    Morimoto, H.3    Haneji, T.4
  • 39
    • 33645824142 scopus 로고    scopus 로고
    • Genistein suppresses proliferation and MET oncogene expression and induces EGR-1 tumor suppressor expression in immortalized human breast epithelial cells
    • Singletary K and Ellington A: Genistein suppresses proliferation and MET oncogene expression and induces EGR-1 tumor suppressor expression in immortalized human breast epithelial cells. Anticancer Res 26: 1039-1048, 2006.
    • (2006) Anticancer Res , vol.26 , pp. 1039-1048
    • Singletary, K.1    Ellington, A.2
  • 40
    • 27644525709 scopus 로고    scopus 로고
    • Suppression of tumor cell invasion by cyclooxygenase inhibitors is mediated by thrombospondin-1 via the early growth response gene Egr-1
    • Moon Y, Bottone FG Jr, McEntee MF and Eling TE: Suppression of tumor cell invasion by cyclooxygenase inhibitors is mediated by thrombospondin-1 via the early growth response gene Egr-1. Mol Cancer Ther 4: 1551-1558, 2005.
    • (2005) Mol Cancer Ther , vol.4 , pp. 1551-1558
    • Moon, Y.1    Bottone Jr, F.G.2    McEntee, M.F.3    Eling, T.E.4
  • 41
    • 30544439107 scopus 로고    scopus 로고
    • Curcumin inhibits human colon cancer cell growth by suppressing gene expression of epidermal growth factor receptor through reducing the activity of the transcription factor Egr-1
    • Chen A, Xu J and Johnson AC: Curcumin inhibits human colon cancer cell growth by suppressing gene expression of epidermal growth factor receptor through reducing the activity of the transcription factor Egr-1. Oncogene 25: 278-287, 2006.
    • (2006) Oncogene , vol.25 , pp. 278-287
    • Chen, A.1    Xu, J.2    Johnson, A.C.3
  • 43
    • 0029909386 scopus 로고    scopus 로고
    • Transcription factor Egr-1 suppresses the growth and transformation of human HT-1080 fibrosarcoma cells by induction of transforming growth factor β1
    • Liu CT, Adamson ED and Mercola D: Transcription factor Egr-1 suppresses the growth and transformation of human HT-1080 fibrosarcoma cells by induction of transforming growth factor β1. Proc Natl Acad Sci USA 93: 11831-11836, 1996.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 11831-11836
    • Liu, C.T.1    Adamson, E.D.2    Mercola, D.3
  • 44
    • 0033548186 scopus 로고    scopus 로고
    • The transcription factor EGR-1 suppresses transformation of human fibrosarcoma HT1080 cells by coordinated induction of transforming growth factor-beta1, fibronectin, and plasminogen activator inhibitor-1
    • Liu C, Yao J, de B, I, Huang RP, Adamson E and Mercola D: The transcription factor EGR-1 suppresses transformation of human fibrosarcoma HT1080 cells by coordinated induction of transforming growth factor-beta1, fibronectin, and plasminogen activator inhibitor-1. J Biol Chem 274: 4400-4411, 1999.
    • (1999) J Biol Chem , vol.274 , pp. 4400-4411
    • Liu, C.1    Yao, J.2    de, B.I.3    Huang, R.P.4    Adamson, E.5    Mercola, D.6
  • 45
    • 0032966363 scopus 로고    scopus 로고
    • Functions of gelsolin: Motility, signaling, apoptosis, cancer
    • Kwiatkowski DJ: Functions of gelsolin: motility, signaling, apoptosis, cancer. Curr Opin Cell Biol 11: 103-108, 1999.
    • (1999) Curr Opin Cell Biol , vol.11 , pp. 103-108
    • Kwiatkowski, D.J.1
  • 46
    • 0344141335 scopus 로고    scopus 로고
    • UV irradiation upregulates Egr-1 expression at transcription level
    • Huang RP, Fan Y and Boynton AL: UV irradiation upregulates Egr-1 expression at transcription level. J Cell Biochem 73: 227-236, 1999.
    • (1999) J Cell Biochem , vol.73 , pp. 227-236
    • Huang, R.P.1    Fan, Y.2    Boynton, A.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.