Sesamol induces apoptosis in human platelets via reactive oxygen species-mediated mitochondrial damage

Biochimie

Volumn 95, Issue 11, 2013, Pages 2060-2068

  Thushara, R M ^a   Hemshekhar, M ^a   Sunitha, K ^a   Kumar, M S ^a,b   Naveen, S ^c   Kemparaju, K ^a   Girish, K S ^a  

^a UNIVERSITY OF MYSORE   (India)

^b Government College for Women   (India)

^c DEFENCE FOOD RESEARCH LABORATORY   (India)

Author keywords

Caspases; Drug overdose; Oxidative stress; Platelet aggregation; Platelet apoptosis; Sesamol

Indexed keywords

CASPASE 3; CASPASE 9; CYTOCHROME C; FIBRINOLYTIC AGENT; PHENOL DERIVATIVE; PHOSPHATIDYLSERINE; REACTIVE OXYGEN METABOLITE; SESAMOL; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL MEMBRANE DEPOLARIZATION; CONTROLLED STUDY; DRUG CYTOTOXICITY; ENZYME ACTIVATION; EXPOSURE; HUMAN; HUMAN CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; OXIDATIVE STRESS; PLANT SEED; SESAME; THROMBOCYTE; THROMBOCYTE AGGREGATION; THROMBOCYTE FUNCTION; WESTERN BLOTTING;

SESAMUM INDICUM;

CASPASES; DRUG OVERDOSE; OXIDATIVE STRESS; PLATELET AGGREGATION; PLATELET APOPTOSIS; SESAMOL;

ANTIOXIDANTS; APOPTOSIS; BENZODIOXOLES; BLOOD PLATELETS; CASPASE 3; CASPASE 9; CYTOCHROMES C; HUMANS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; OXIDATIVE STRESS; PHENOLS; PLATELET AGGREGATION; PLATELET AGGREGATION INHIBITORS; REACTIVE OXYGEN SPECIES;

EID: 84885054568     PISSN: 03009084     EISSN: 61831638     Source Type: Journal    
DOI: 10.1016/j.biochi.2013.07.032     Document Type: Article

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