메뉴 건너뛰기




Volumn 116, Issue , 2013, Pages 219-226

Molecular identification and cellular localization of a potential transport system involved in cystine/cysteine uptake in human lenses

Author keywords

Age related nuclear cataract; Alanine serine cysteine transporter; Cystine glutamate exchanger; Excitatory amino acid transporters; Lens; Protein mixed disulfides

Indexed keywords

ALANYLSERYLCYSTEINE TRANSPORTER 2; AMINO ACID TRANSPORTER; CYSTEINE; CYSTINE; EXCITATORY AMINO ACID TRANSPORTER 4; GLUTAMATE TRANSPORTER; PROTEIN S S CYSTEINE; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

EID: 84885047821     PISSN: 00144835     EISSN: 10960007     Source Type: Journal    
DOI: 10.1016/j.exer.2013.09.002     Document Type: Article
Times cited : (27)

References (43)
  • 1
    • 77952788436 scopus 로고    scopus 로고
    • On the growth and internal structure of the human lens
    • Augusteyn R.C. On the growth and internal structure of the human lens. Exp. Eye Res. 2010, 90:643-654.
    • (2010) Exp. Eye Res. , vol.90 , pp. 643-654
    • Augusteyn, R.C.1
  • 3
    • 0022969399 scopus 로고
    • Exchange of cystine and glutamate across plasma membrane of human fibroblasts
    • Bannai S. Exchange of cystine and glutamate across plasma membrane of human fibroblasts. J.Biochem. 1986, 261:2256-2263.
    • (1986) J.Biochem. , vol.261 , pp. 2256-2263
    • Bannai, S.1
  • 4
    • 33646018919 scopus 로고    scopus 로고
    • Distribution of the cystine/glutamate antiporter system xc- in the brain, kidney, and duodenum
    • Burdo J., Dargusch R., Schubert D. Distribution of the cystine/glutamate antiporter system xc- in the brain, kidney, and duodenum. J.Histochem. Cytochem. 2006, 54:549-557.
    • (2006) J.Histochem. Cytochem. , vol.54 , pp. 549-557
    • Burdo, J.1    Dargusch, R.2    Schubert, D.3
  • 5
    • 79951682959 scopus 로고    scopus 로고
    • Invivo inhibition of l-buthionine-(S, R)-sulfoximine-induced cataracts by a novel antioxidant, N-acetylcysteine amide
    • Carey J.W., Pinarci E.Y., Penugonda S., Karacal H., Ercal N. Invivo inhibition of l-buthionine-(S, R)-sulfoximine-induced cataracts by a novel antioxidant, N-acetylcysteine amide. Free Radic. Biol. Med. 2011, 50:722-729.
    • (2011) Free Radic. Biol. Med. , vol.50 , pp. 722-729
    • Carey, J.W.1    Pinarci, E.Y.2    Penugonda, S.3    Karacal, H.4    Ercal, N.5
  • 6
  • 7
    • 0030608873 scopus 로고    scopus 로고
    • Steroid-induced cataract: new perspectives from invitro and lens culture studies
    • Dickerson J.E., Dotzel E., Clark A. Steroid-induced cataract: new perspectives from invitro and lens culture studies. Exp. Eye Res. 1997, 65:507-516.
    • (1997) Exp. Eye Res. , vol.65 , pp. 507-516
    • Dickerson, J.E.1    Dotzel, E.2    Clark, A.3
  • 9
    • 33645821925 scopus 로고    scopus 로고
    • Expression of the cystine-glutamate exchanger (xc-) in retinal ganglion cells and regulation by nitric oxide and oxidative stress
    • Dun Y., Mysona B., Van Ells T., Amarnath L., Ola M., Ganapathy V., Smith S. Expression of the cystine-glutamate exchanger (xc-) in retinal ganglion cells and regulation by nitric oxide and oxidative stress. Cell Tissue Res. 2006, 324:189-202.
    • (2006) Cell Tissue Res. , vol.324 , pp. 189-202
    • Dun, Y.1    Mysona, B.2    Van Ells, T.3    Amarnath, L.4    Ola, M.5    Ganapathy, V.6    Smith, S.7
  • 10
    • 33749057549 scopus 로고    scopus 로고
    • Gap junctions and connexon hemichannels in human embryonic stem cells
    • Huettner J., Lu A., Qu Y., Wu Y., Kim M., McDonald J. Gap junctions and connexon hemichannels in human embryonic stem cells. Stem Cells 2006, 24:1654-1667.
    • (2006) Stem Cells , vol.24 , pp. 1654-1667
    • Huettner, J.1    Lu, A.2    Qu, Y.3    Wu, Y.4    Kim, M.5    McDonald, J.6
  • 11
    • 0346096980 scopus 로고    scopus 로고
    • Gap junction processing and redistribution revealed by quantitative optical measurements of connexin46 epitopes in the lens
    • Jacobs M.D., Soeller C., Sisley A.M.G., Cannell M.B., Donaldson P.J. Gap junction processing and redistribution revealed by quantitative optical measurements of connexin46 epitopes in the lens. Invest. Ophthalmol. Vis. Sci. 2004, 45:191-199.
    • (2004) Invest. Ophthalmol. Vis. Sci. , vol.45 , pp. 191-199
    • Jacobs, M.D.1    Soeller, C.2    Sisley, A.M.G.3    Cannell, M.B.4    Donaldson, P.J.5
  • 13
    • 0028970667 scopus 로고
    • An ultrastructural analysis of the epithelial-fiber interface (EFI) in primate lenses
    • Kuszak J., Novak L., Brown H. An ultrastructural analysis of the epithelial-fiber interface (EFI) in primate lenses. Exp. Eye Res. 1995, 61:579-597.
    • (1995) Exp. Eye Res. , vol.61 , pp. 579-597
    • Kuszak, J.1    Novak, L.2    Brown, H.3
  • 14
    • 34047265311 scopus 로고    scopus 로고
    • Regional differences in cystine accumulation point to a sutural delivery pathway to the lens core
    • Li L., Lim J., Jacobs M.D., Kistler J., Donaldson P.J. Regional differences in cystine accumulation point to a sutural delivery pathway to the lens core. Invest. Ophthalmol. Vis. Sci. 2007, 48:1253-1260.
    • (2007) Invest. Ophthalmol. Vis. Sci. , vol.48 , pp. 1253-1260
    • Li, L.1    Lim, J.2    Jacobs, M.D.3    Kistler, J.4    Donaldson, P.J.5
  • 15
    • 24644461194 scopus 로고    scopus 로고
    • Molecular characterization of the cystine/glutamate exchanger and the excitatory amino acid transporters in the rat lens
    • Lim J., Lam Y.C., Kistler J., Donaldson P.J. Molecular characterization of the cystine/glutamate exchanger and the excitatory amino acid transporters in the rat lens. Invest. Ophthalmol. Vis. Sci. 2005, 46:2869-2877.
    • (2005) Invest. Ophthalmol. Vis. Sci. , vol.46 , pp. 2869-2877
    • Lim, J.1    Lam, Y.C.2    Kistler, J.3    Donaldson, P.J.4
  • 16
    • 33744914329 scopus 로고    scopus 로고
    • Molecular identification and characterisation of the glycine transporter (GLYT1) and the glutamine/glutamate transporter (ASCT2) in the rat lens
    • Lim J., Lorentzen K.A., Kistler J., Donaldson P.J. Molecular identification and characterisation of the glycine transporter (GLYT1) and the glutamine/glutamate transporter (ASCT2) in the rat lens. Exp. Eye Res. 2006, 83:447-455.
    • (2006) Exp. Eye Res. , vol.83 , pp. 447-455
    • Lim, J.1    Lorentzen, K.A.2    Kistler, J.3    Donaldson, P.J.4
  • 17
    • 70349241746 scopus 로고    scopus 로고
    • Confocal microscopy reveals zones of membrane remodeling in the outer cortex of the human lens
    • Lim J.C., Walker K.L., Sherwin T., Schey K.L., Donaldson P.J. Confocal microscopy reveals zones of membrane remodeling in the outer cortex of the human lens. Invest. Ophthalmol. Vis. Sci. 2009, 50:4304-4310.
    • (2009) Invest. Ophthalmol. Vis. Sci. , vol.50 , pp. 4304-4310
    • Lim, J.C.1    Walker, K.L.2    Sherwin, T.3    Schey, K.L.4    Donaldson, P.J.5
  • 18
    • 0003015118 scopus 로고    scopus 로고
    • Protein-thiol mixed disulfides and thioltransferase in the lens
    • Springer US, K. Green, H. Edelhauser, R. Hackett, D. Hull, D. Potter, R. Tripathi (Eds.)
    • Lou M.F. Protein-thiol mixed disulfides and thioltransferase in the lens. Advances in Ocular Toxicology 1997, 27-46. Springer US. K. Green, H. Edelhauser, R. Hackett, D. Hull, D. Potter, R. Tripathi (Eds.).
    • (1997) Advances in Ocular Toxicology , pp. 27-46
    • Lou, M.F.1
  • 19
    • 0034092928 scopus 로고    scopus 로고
    • Thiol regulation in the lens
    • Lou M.F. Thiol regulation in the lens. J.Ocul. Pharmacol. Ther. 2000, 16:137-148.
    • (2000) J.Ocul. Pharmacol. Ther. , vol.16 , pp. 137-148
    • Lou, M.F.1
  • 20
    • 0042198801 scopus 로고    scopus 로고
    • Redox regulation in the lens
    • Lou M.F. Redox regulation in the lens. Prog. Retin. Eye Res. 2003, 22:657-682.
    • (2003) Prog. Retin. Eye Res. , vol.22 , pp. 657-682
    • Lou, M.F.1
  • 21
    • 0027087293 scopus 로고
    • Protein-thiol mixed disulfides in human lens
    • Lou M.F., Dickerson J.E. Protein-thiol mixed disulfides in human lens. Exp. Eye Res. 1992, 55:889-896.
    • (1992) Exp. Eye Res. , vol.55 , pp. 889-896
    • Lou, M.F.1    Dickerson, J.E.2
  • 22
    • 0036640537 scopus 로고    scopus 로고
    • Cerebral cystine uptake: a tale of two transporters
    • McBean G.J. Cerebral cystine uptake: a tale of two transporters. Trends Pharmacol. Sci. 2002, 23:299-302.
    • (2002) Trends Pharmacol. Sci. , vol.23 , pp. 299-302
    • McBean, G.J.1
  • 23
    • 0022644198 scopus 로고
    • Evidence for two physiologically distinct gap junctions expressed by the chick lens epithelial cell
    • Miller T., Goodenough D. Evidence for two physiologically distinct gap junctions expressed by the chick lens epithelial cell. J.Cell Biol. 1986, 102:194-199.
    • (1986) J.Cell Biol. , vol.102 , pp. 194-199
    • Miller, T.1    Goodenough, D.2
  • 24
    • 32944455784 scopus 로고    scopus 로고
    • Induction of thioltransferase and thioredoxin/thioredoxin reductase systems in cultured porcine lenses under oxidative stress
    • Moon S., Fernando M.R., Lou M.F. Induction of thioltransferase and thioredoxin/thioredoxin reductase systems in cultured porcine lenses under oxidative stress. Invest. Ophthalmol. Vis. Sci. 2005, 46:3783-3789.
    • (2005) Invest. Ophthalmol. Vis. Sci. , vol.46 , pp. 3783-3789
    • Moon, S.1    Fernando, M.R.2    Lou, M.F.3
  • 25
    • 0032531211 scopus 로고    scopus 로고
    • Effects of N-acetylcysteine and 2,3-dimercaptosuccinic acid on lead induced oxidative stress in rat lenses
    • Neal R., Cooper K., Gurer H., Ercal N. Effects of N-acetylcysteine and 2,3-dimercaptosuccinic acid on lead induced oxidative stress in rat lenses. Toxicology 1998, 130:167-174.
    • (1998) Toxicology , vol.130 , pp. 167-174
    • Neal, R.1    Cooper, K.2    Gurer, H.3    Ercal, N.4
  • 26
    • 78649849854 scopus 로고    scopus 로고
    • Cisplatin upregulates glutamine transport in human intestinal epithelial cells: the protective mechanism of glutamine on intestinal mucosa after chemotherapy
    • Nose S., Wasa M., Tazuke Y., Owari M., Fukuzawa M. Cisplatin upregulates glutamine transport in human intestinal epithelial cells: the protective mechanism of glutamine on intestinal mucosa after chemotherapy. JPEN J. Parenter. Enteral. Nutr. 2010, 34:530-537.
    • (2010) JPEN J. Parenter. Enteral. Nutr. , vol.34 , pp. 530-537
    • Nose, S.1    Wasa, M.2    Tazuke, Y.3    Owari, M.4    Fukuzawa, M.5
  • 27
    • 11844278550 scopus 로고    scopus 로고
    • The presence of a transsulfuration pathway in the lens: a new oxidative stress defense system
    • Persa C., Pierce A., Ma Z., Kabil O., Lou M.F. The presence of a transsulfuration pathway in the lens: a new oxidative stress defense system. Exp. Eye Res. 2004, 79:875-886.
    • (2004) Exp. Eye Res. , vol.79 , pp. 875-886
    • Persa, C.1    Pierce, A.2    Ma, Z.3    Kabil, O.4    Lou, M.F.5
  • 29
    • 0020614367 scopus 로고
    • The electrical coupling of epithelium and fibers in the frog lens
    • Rae J., Kuszak J. The electrical coupling of epithelium and fibers in the frog lens. Exp. Eye Res. 1983, 36:317-326.
    • (1983) Exp. Eye Res. , vol.36 , pp. 317-326
    • Rae, J.1    Kuszak, J.2
  • 30
    • 0033597349 scopus 로고    scopus 로고
    • Cloning and expression of a plasma membrane cystine/glutamate exchange transporter composed of two distinct proteins
    • Sato H., Tamba M., Ishii T., Bannai S. Cloning and expression of a plasma membrane cystine/glutamate exchange transporter composed of two distinct proteins. J.Biochem. 1999, 274:11455-11458.
    • (1999) J.Biochem. , vol.274 , pp. 11455-11458
    • Sato, H.1    Tamba, M.2    Ishii, T.3    Bannai, S.4
  • 31
    • 0035920108 scopus 로고    scopus 로고
    • Truncated forms of the dual function human ASCT2 neutral amino acid transporter/retroviral receptor are translationally initiated at multiple alternative CUG and GUG codons
    • Tailor C., Marin M., Nouri A., Kavanaugh M., Kabat D. Truncated forms of the dual function human ASCT2 neutral amino acid transporter/retroviral receptor are translationally initiated at multiple alternative CUG and GUG codons. J.Biochem. 2001, 276:27221-27230.
    • (2001) J.Biochem. , vol.276 , pp. 27221-27230
    • Tailor, C.1    Marin, M.2    Nouri, A.3    Kavanaugh, M.4    Kabat, D.5
  • 32
    • 0030296072 scopus 로고    scopus 로고
    • Increase in the intramolecular disulfide bonding of alpha-A crystallin during aging of the human lens
    • Takemoto L. Increase in the intramolecular disulfide bonding of alpha-A crystallin during aging of the human lens. Exp. Eye Res. 1996, 63:585-590.
    • (1996) Exp. Eye Res. , vol.63 , pp. 585-590
    • Takemoto, L.1
  • 33
    • 0344393085 scopus 로고    scopus 로고
    • The l-isomer-selective transport of aspartic acid is mediated by ASCT2 at the blood-brain barrier
    • Tetsuka K., Takanaga H., Ohtsuki S., Hosoya K., Terasaki T. The l-isomer-selective transport of aspartic acid is mediated by ASCT2 at the blood-brain barrier. J.Neurochem. 2003, 87:891-901.
    • (2003) J.Neurochem. , vol.87 , pp. 891-901
    • Tetsuka, K.1    Takanaga, H.2    Ohtsuki, S.3    Hosoya, K.4    Terasaki, T.5
  • 34
    • 18044388716 scopus 로고    scopus 로고
    • Age-related nuclear cataract-oxidation is the key
    • Truscott R.J. Age-related nuclear cataract-oxidation is the key. Exp. Eye Res. 2005, 80:709-725.
    • (2005) Exp. Eye Res. , vol.80 , pp. 709-725
    • Truscott, R.J.1
  • 35
    • 77949531289 scopus 로고    scopus 로고
    • Are ancient proteins responsible for the age-related decline in health and fitness?
    • Truscott R.J. Are ancient proteins responsible for the age-related decline in health and fitness?. Rejuvenation Res. 2010, 13:83-89.
    • (2010) Rejuvenation Res. , vol.13 , pp. 83-89
    • Truscott, R.J.1
  • 38
    • 0034796442 scopus 로고    scopus 로고
    • Function and structure of heterodimeric amino acid transporters
    • Wagner C.A., Lang F., Broer S. Function and structure of heterodimeric amino acid transporters. Am. J. Physiol-cell Physiol. 2001, 281:C1077-C1093.
    • (2001) Am. J. Physiol-cell Physiol. , vol.281
    • Wagner, C.A.1    Lang, F.2    Broer, S.3
  • 39
    • 77649259579 scopus 로고    scopus 로고
    • Hyperoxia-induced lens damage in rabbit: protective effects of N-acetylcysteine
    • Wang P., Liu X.C., Yan H., Li M.Y. Hyperoxia-induced lens damage in rabbit: protective effects of N-acetylcysteine. Mol. Vis. 2009, 15:2945-2952.
    • (2009) Mol. Vis. , vol.15 , pp. 2945-2952
    • Wang, P.1    Liu, X.C.2    Yan, H.3    Li, M.Y.4
  • 40
    • 0030596740 scopus 로고    scopus 로고
    • Oxidative-stress induced protein glutathione mixed-disulfide formation in the ocular lens
    • Willis J.A., Schleich T. Oxidative-stress induced protein glutathione mixed-disulfide formation in the ocular lens. Biochim. Biophys. Acta -Mol. Cell Res. 1996, 1313:20-28.
    • (1996) Biochim. Biophys. Acta -Mol. Cell Res. , vol.1313 , pp. 20-28
    • Willis, J.A.1    Schleich, T.2
  • 41
    • 79955958811 scopus 로고    scopus 로고
    • Effect of age on the thioltransferase (glutaredoxin) and thioredoxin systems in the human lens
    • Xing K., Lou M. Effect of age on the thioltransferase (glutaredoxin) and thioredoxin systems in the human lens. Invest. Ophthalmol. Vis. Sci. 2010, 51:6598-6604.
    • (2010) Invest. Ophthalmol. Vis. Sci. , vol.51 , pp. 6598-6604
    • Xing, K.1    Lou, M.2
  • 42
    • 34249049809 scopus 로고    scopus 로고
    • Revival of glutathione reductase in human cataractous and clear lens extracts by thioredoxin and thioredoxin reductase, in conjunction with alpha-crystallin or thioltransferase
    • Yan H., Harding J.J., Xing K., Lou M.F. Revival of glutathione reductase in human cataractous and clear lens extracts by thioredoxin and thioredoxin reductase, in conjunction with alpha-crystallin or thioltransferase. Curr. Eye Res. 2007, 32:455-463.
    • (2007) Curr. Eye Res. , vol.32 , pp. 455-463
    • Yan, H.1    Harding, J.J.2    Xing, K.3    Lou, M.F.4
  • 43
    • 44149127234 scopus 로고    scopus 로고
    • Effects of N-acetylcysteine and glutathione ethyl ester drops on streptozotocin-induced diabetic cataract in rats
    • Zhang S., Chai F., Yan H., Guo Y., Harding J.J. Effects of N-acetylcysteine and glutathione ethyl ester drops on streptozotocin-induced diabetic cataract in rats. Mol. Vis. 2008, 14:862-870.
    • (2008) Mol. Vis. , vol.14 , pp. 862-870
    • Zhang, S.1    Chai, F.2    Yan, H.3    Guo, Y.4    Harding, J.J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.