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Bioorganic and Medicinal Chemistry

Volumn 21, Issue 20, 2013, Pages 6239-6246

RNA-aptamers that modulate the RhoGEF activity of Tiam1

(3) Niebel, Björn a Wosnitza, Christine I a Famulok, Michael a

a UNIVERSITY OF BONN (Germany)

Author keywords

Anti RhoGEF aptamer; In vitro selection; RNA aptamers; SELEX; Tiaml

Indexed keywords

APTAMER; CARRIER PROTEINS AND BINDING PROTEINS; CYTOHESIN 2; GUANINE NUCLEOTIDE EXCHANGE FACTOR; NUCLEOTIDE; RAC1 PROTEIN; RAC2 PROTEIN; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; RNA APTAMER; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BIOTINYLATION; CONTROLLED STUDY; ENZYME ACTIVATION; GENE FUNCTION; HUMAN; IN VITRO STUDY; ONCOGENE; PROTEIN EXPRESSION; PROTEIN MOTIF; REGULATORY MECHANISM; RNA FOLDING; TIAM1 GENE;

ANTI-RHOGEF APTAMER; IN VITRO SELECTION; RNA APTAMERS; SELEX; TIAML;

ANIMALS; APTAMERS, NUCLEOTIDE; BINDING SITES; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HUMANS; MICE; MODELS, MOLECULAR; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RHO GUANINE NUCLEOTIDE EXCHANGE FACTORS;

EID: 84885023076 PISSN: 09680896 EISSN: 14643391 Source Type: Journal
DOI: 10.1016/j.bmc.2013.05.021 Document Type: Article

Times cited : (10)

References (51)

1
- 78649487698
- D. Vigil, J. Cherfils, K.L. Rossman, and C.J. Der Nat. Rev. Cancer 10 2010 842
- (2010) Nat. Rev. Cancer , vol.10 , pp. 842
- Vigil, D.¹ Cherfils, J.² Rossman, K.L.³ Der, C.J.⁴

2
- 0032559362
- A. Hall Science 279 1998 509
- (1998) Science , vol.279 , pp. 509
- Hall, A.¹

3
- 0034865456
- A.J. Ridley J. Cell Sci. 114 2001 2713
- (2001) J. Cell Sci. , vol.114 , pp. 2713
- Ridley, A.J.¹

4
- 0036488510
- E. Sahai, and C.J. Marshall Nat. Rev. Cancer 2 2002 133
- (2002) Nat. Rev. Cancer , vol.2 , pp. 133
- Sahai, E.¹ Marshall, C.J.²

5
- 0021825489
- A. Eva, and S.A. Aaronson Nature 316 1985 273
- (1985) Nature , vol.316 , pp. 273
- Eva, A.¹ Aaronson, S.A.²

6
- 0029784842
- I.P. Whitehead, R. Khosravi-Far, H. Kirk, G. Trigo-Gonzalez, C.J. Der, and R. Kay J. Biol. Chem. 271 1996 18643
- (1996) J. Biol. Chem. , vol.271 , pp. 18643
- Whitehead, I.P.¹ Khosravi-Far, R.² Kirk, H.³ Trigo-Gonzalez, G.⁴ Der, C.J.⁵ Kay, R.⁶

7
- 0029917989
- A.M. Chan, S. Takai, K. Yamada, and T. Miki Oncogene 12 1996 1259
- (1996) Oncogene , vol.12 , pp. 1259
- Chan, A.M.¹ Takai, S.² Yamada, K.³ Miki, T.⁴

8
- 0028948329
- I. Whitehead, H. Kirk, and R. Kay Oncogene 10 1995 713
- (1995) Oncogene , vol.10 , pp. 713
- Whitehead, I.¹ Kirk, H.² Kay, R.³

9
- 0029155976
- I. Whitehead, H. Kirk, C. Tognon, G. Trigo-Gonzalez, and R. Kay J. Biol. Chem. 270 1995 18388
- (1995) J. Biol. Chem. , vol.270 , pp. 18388
- Whitehead, I.¹ Kirk, H.² Tognon, C.³ Trigo-Gonzalez, G.⁴ Kay, R.⁵

10
- 0028110120
- Y. Horii, J.F. Beeler, K. Sakaguchi, M. Tachibana, and T. Miki EMBO J. 13 1994 4776
- (1994) EMBO J. , vol.13 , pp. 4776
- Horii, Y.¹ Beeler, J.F.² Sakaguchi, K.³ Tachibana, M.⁴ Miki, T.⁵

11
- 0028266937
- A.M. Chan, E.S. McGovern, G. Catalano, T.P. Fleming, and T. Miki Oncogene 9 1994 1057
- (1994) Oncogene , vol.9 , pp. 1057
- Chan, A.M.¹ McGovern, E.S.² Catalano, G.³ Fleming, T.P.⁴ Miki, T.⁵

12
- 0024433697
- S. Katzav, D. Martin-Zanca, and M. Barbacid EMBO J. 8 1989 2283
- (1989) EMBO J. , vol.8 , pp. 2283
- Katzav, S.¹ Martin-Zanca, D.² Barbacid, M.³

13
- 0028225439
- G.G. Habets, E.H. Scholtes, D. Zuydgeest, R.A. van der Kammen, J.C. Stam, A. Berns, and J.G. Collard Cell 77 1994 537
- (1994) Cell , vol.77 , pp. 537
- Habets, G.G.¹ Scholtes, E.H.² Zuydgeest, D.³ Van Der Kammen, R.A.⁴ Stam, J.C.⁵ Berns, A.⁶ Collard, J.G.⁷

14
- 0029079431
- F. Michiels, G.G. Habets, J.C. Stam, R.A. van der Kammen, and J.G. Collard Nature 375 1995 338
- (1995) Nature , vol.375 , pp. 338
- Michiels, F.¹ Habets, G.G.² Stam, J.C.³ Van Der Kammen, R.A.⁴ Collard, J.G.⁵

15
- 32144431569
- L.C. Haeusler, L. Hemsath, D. Fiegen, L. Blumenstein, U. Herbrand, P. Stege, R. Dvorsky, and M.R. Ahmadian Methods Enzymol. 406 2006 1
- (2006) Methods Enzymol. , vol.406 , pp. 1
- Haeusler, L.C.¹ Hemsath, L.² Fiegen, D.³ Blumenstein, L.⁴ Herbrand, U.⁵ Stege, P.⁶ Dvorsky, R.⁷ Ahmadian, M.R.⁸

16
- 0037142034
- A. Malliri, R.A. van der Kammen, K. Clark, M. van der Valk, F. Michiels, and J.G. Collard Nature 417 2002 867
- (2002) Nature , vol.417 , pp. 867
- Malliri, A.¹ Van Der Kammen, R.A.² Clark, K.³ Van Der Valk, M.⁴ Michiels, F.⁵ Collard, J.G.⁶

17
- 42549116142
- A. Walch, S. Seidl, C. Hermannstadter, S. Rauser, J. Deplazes, R. Langer, C.H. von Weyhern, M. Sarbia, R. Busch, M. Feith, S. Gillen, H. Hofler, and B. Luber Mod. Pathol. 21 2008 544
- (2008) Mod. Pathol. , vol.21 , pp. 544
- Walch, A.¹ Seidl, S.² Hermannstadter, C.³ Rauser, S.⁴ Deplazes, J.⁵ Langer, R.⁶ Von Weyhern, C.H.⁷ Sarbia, M.⁸ Busch, R.⁹ Feith, M.¹⁰ Gillen, S.¹¹ Hofler, H.¹² Luber, B.¹³

18
- 33750213029
- R. Engers, M. Mueller, A. Walter, J.G. Collard, R. Willers, and H.E. Gabbert Br. J. Cancer 95 2006 1081
- (2006) Br. J. Cancer , vol.95 , pp. 1081
- Engers, R.¹ Mueller, M.² Walter, A.³ Collard, J.G.⁴ Willers, R.⁵ Gabbert, H.E.⁶

19
- 17844400108
- M.E. Minard, M.H. Herynk, J.G. Collard, and G.E. Gallick Oncogene 24 2005 2568
- (2005) Oncogene , vol.24 , pp. 2568
- Minard, M.E.¹ Herynk, M.H.² Collard, J.G.³ Gallick, G.E.⁴

20
- 0030698191
- P.L. Hordijk, J.P. ten Klooster, R.A. van der Kammen, F. Michiels, L.C. Oomen, and J.G. Collard Science 278 1997 1464
- (1997) Science , vol.278 , pp. 1464
- Hordijk, P.L.¹ Ten Klooster, J.P.² Van Der Kammen, R.A.³ Michiels, F.⁴ Oomen, L.C.⁵ Collard, J.G.⁶

21
- 7244251723
- K. Uhlenbrock, A. Eberth, U. Herbrand, N. Daryab, P. Stege, F. Meier, P. Friedl, J.G. Collard, and M.R. Ahmadian J. Cell Sci. 117 2004 4863
- (2004) J. Cell Sci. , vol.117 , pp. 4863
- Uhlenbrock, K.¹ Eberth, A.² Herbrand, U.³ Daryab, N.⁴ Stege, P.⁵ Meier, F.⁶ Friedl, P.⁷ Collard, J.G.⁸ Ahmadian, M.R.⁹

22
- 67649566345
- N. Bouquier, E. Vignal, S. Charrasse, M. Weill, S. Schmidt, J.P. Leonetti, A. Blangy, and P. Fort Chem. Biol. 16 2009 657
- (2009) Chem. Biol. , vol.16 , pp. 657
- Bouquier, N.¹ Vignal, E.² Charrasse, S.³ Weill, M.⁴ Schmidt, S.⁵ Leonetti, J.P.⁶ Blangy, A.⁷ Fort, P.⁸

23
- 33748642768
- A. Blangy, N. Bouquier, C. Gauthier-Rouviere, S. Schmidt, A. Debant, J.P. Leonetti, and P. Fort Biol. Eur. Cell Biol. Org. 98 2006 511
- (2006) Biol. Eur. Cell Biol. Org. , vol.98 , pp. 511
- Blangy, A.¹ Bouquier, N.² Gauthier-Rouviere, C.³ Schmidt, S.⁴ Debant, A.⁵ Leonetti, J.P.⁶ Fort, P.⁷

24
- 0037125232
- S. Schmidt, S. Diriong, J. Mery, E. Fabbrizio, and A. Debant FEBS Lett. 523 2002 35
- (2002) FEBS Lett. , vol.523 , pp. 35
- Schmidt, S.¹ Diriong, S.² Mery, J.³ Fabbrizio, E.⁴ Debant, A.⁵

25
- 84886085460
- N. Bouquier, S. Fromont, J.C. Zeeh, C. Auziol, P. Larrousse, B. Robert, M. Zeghouf, J. Cherfils, A. Debant, S. Schmidt, and G. Mayer Angew. Chem., Int. Ed. 48 2009 2672
- (2009) Angew. Chem., Int. Ed. , vol.48 , pp. 2672
- Bouquier, N.¹ Fromont, S.² Zeeh, J.C.³ Auziol, C.⁴ Larrousse, P.⁵ Robert, B.⁶ Zeghouf, M.⁷ Cherfils, J.⁸ Debant, A.⁹ Schmidt, S.¹⁰ Mayer, G.¹¹

26
- 77956950174
- B. Niebel, C. Lentz, M. Pofahl, G. Mayer, A. Hoerauf, K.M. Pfarr, and M. Famulok Chemistry 16 2010 11100
- (2010) Chemistry , vol.16 , pp. 11100
- Niebel, B.¹ Lentz, C.² Pofahl, M.³ Mayer, G.⁴ Hoerauf, A.⁵ Pfarr, K.M.⁶ Famulok, M.⁷

27
- 84859721334
- F. Rohrbach, H. Karadeniz, A. Erdem, M. Famulok, and G. Mayer Anal. Biochem. 421 2012 454
- (2012) Anal. Biochem. , vol.421 , pp. 454
- Rohrbach, F.¹ Karadeniz, H.² Erdem, A.³ Famulok, M.⁴ Mayer, G.⁵

28
- 0035942221
- G. Mayer, M. Blind, W. Nagel, T. Bohm, T. Knorr, C.L. Jackson, W. Kolanus, and M. Famulok Proc. Natl. Acad. Sci. U.S.A. 98 2001 4961
- (2001) Proc. Natl. Acad. Sci. U.S.A. , vol.98 , pp. 4961
- Mayer, G.¹ Blind, M.² Nagel, W.³ Bohm, T.⁴ Knorr, T.⁵ Jackson, C.L.⁶ Kolanus, W.⁷ Famulok, M.⁸

29
- 3843086053
- M.G. Theis, A. Knorre, B. Kellersch, J. Moelleken, F. Wieland, W. Kolanus, and M. Famulok Proc. Natl. Acad. Sci. U.S.A. 101 2004 11221
- (2004) Proc. Natl. Acad. Sci. U.S.A. , vol.101 , pp. 11221
- Theis, M.G.¹ Knorre, A.² Kellersch, B.³ Moelleken, J.⁴ Wieland, F.⁵ Kolanus, W.⁶ Famulok, M.⁷

30
- 84863438784
- M. Hons, B. Niebel, N. Karnowski, B. Weiche, and M. Famulok ChemBioChem 13 2012 1433
- (2012) ChemBioChem , vol.13 , pp. 1433
- Hons, M.¹ Niebel, B.² Karnowski, N.³ Weiche, B.⁴ Famulok, M.⁵

31
- 70949093261
- M. Famulok J. Med. Chem. 52 2009 6951
- (2009) J. Med. Chem. , vol.52 , pp. 6951
- Famulok, M.¹

32
- 33845863903
- M. Hafner, A. Schmitz, I. Grune, S.G. Srivatsan, B. Paul, W. Kolanus, T. Quast, E. Kremmer, I. Bauer, and M. Famulok Nature 444 2006 941
- (2006) Nature , vol.444 , pp. 941
- Hafner, M.¹ Schmitz, A.² Grune, I.³ Srivatsan, S.G.⁴ Paul, B.⁵ Kolanus, W.⁶ Quast, T.⁷ Kremmer, E.⁸ Bauer, I.⁹ Famulok, M.¹⁰

33
- 42049112740
- M. Hafner, E. Vianini, B. Albertoni, L. Marchetti, I. Grüne, C. Gloeckner, and M. Famulok Nat. Protoc. 3 2008 579
- (2008) Nat. Protoc. , vol.3 , pp. 579
- Hafner, M.¹ Vianini, E.² Albertoni, B.³ Marchetti, L.⁴ Grüne, I.⁵ Gloeckner, C.⁶ Famulok, M.⁷

34
- 34447574625
- S. Yamazaki, L. Tan, G. Mayer, J.S. Hartig, J.N. Song, S. Reuter, T. Restle, S.D. Laufer, D. Grohmann, H.G. Kräusslich, J. Bajorath, and M. Famulok Chem. Biol. 14 2007 804
- (2007) Chem. Biol. , vol.14 , pp. 804
- Yamazaki, S.¹ Tan, L.² Mayer, G.³ Hartig, J.S.⁴ Song, J.N.⁵ Reuter, S.⁶ Restle, T.⁷ Laufer, S.D.⁸ Grohmann, D.⁹ Kräusslich, H.G.¹⁰ Bajorath, J.¹¹ Famulok, M.¹²

35
- 84255201129
- M. Famulok, and G. Mayer Acc. Chem. Res. 44 2011 1349
- (2011) Acc. Chem. Res. , vol.44 , pp. 1349
- Famulok, M.¹ Mayer, G.²

36
- 30044449636
- H. Kettenberger, A. Eisenführ, F. Brueckner, M. Theis, M. Famulok, and P. Cramer Nat. Struct. Mol. Biol. 13 2006 44
- (2006) Nat. Struct. Mol. Biol. , vol.13 , pp. 44
- Kettenberger, H.¹ Eisenführ, A.² Brueckner, F.³ Theis, M.⁴ Famulok, M.⁵ Cramer, P.⁶

37
- 0029972909
- Y. Yang, M. Kochoyan, P. Burgstaller, E. Westhof, and M. Famulok Science 272 1996 1343
- (1996) Science , vol.272 , pp. 1343
- Yang, Y.¹ Kochoyan, M.² Burgstaller, P.³ Westhof, E.⁴ Famulok, M.⁵

38
- 4544376496
- S. Jäger, and M. Famulok Angew. Chem., Int. Ed. 43 2004 3337
- (2004) Angew. Chem., Int. Ed. , vol.43 , pp. 3337
- Jäger, S.¹ Famulok, M.²

39
- 27544486140
- S. Jäger, G. Rasched, H. Kornreich-Leshem, M. Engeser, O. Thum, and M. Famulok J. Am. Chem. Soc. 127 2005 15071
- (2005) J. Am. Chem. Soc. , vol.127 , pp. 15071
- Jäger, S.¹ Rasched, G.² Kornreich-Leshem, H.³ Engeser, M.⁴ Thum, O.⁵ Famulok, M.⁶

40
- 0035813885
- O. Thum, S. Jäger, and M. Famulok Angew. Chem., Int. Ed. 40 2001 3990
- (2001) Angew. Chem., Int. Ed. , vol.40 , pp. 3990
- Thum, O.¹ Jäger, S.² Famulok, M.³

41
- 84865847867
- J.L. Vinkenborg, G. Mayer, and M. Famulok Angew. Chem., Int. Ed. 51 2012 9176
- (2012) Angew. Chem., Int. Ed. , vol.51 , pp. 9176
- Vinkenborg, J.L.¹ Mayer, G.² Famulok, M.³

42
- 0027995790
- P. Burgstaller, and M. Famulok Angew. Chem., Int. Ed. 33 1994 1084
- (1994) Angew. Chem., Int. Ed. , vol.33 , pp. 1084
- Burgstaller, P.¹ Famulok, M.²

43
- 0028874701
- P. Burgstaller, M. Kochoyan, and M. Famulok Nucleic Acids Res. 23 1995 4769
- (1995) Nucleic Acids Res. , vol.23 , pp. 4769
- Burgstaller, P.¹ Kochoyan, M.² Famulok, M.³

44
- 0028011717
- M. Famulok J. Am. Chem. Soc. 116 1994 1698
- (1994) J. Am. Chem. Soc. , vol.116 , pp. 1698
- Famulok, M.¹

45
- 0029943824
- M. Famulok, and A. Hüttenhofer Biochemistry 35 1996 4265
- (1996) Biochemistry , vol.35 , pp. 4265
- Famulok, M.¹ Hüttenhofer, A.²

46
- 16244412610
- E.J. Merino, K.A. Wilkinson, J.L. Coughlan, and K.M. Weeks J. Am. Chem. Soc. 127 2005 4223
- (2005) J. Am. Chem. Soc. , vol.127 , pp. 4223
- Merino, E.J.¹ Wilkinson, K.A.² Coughlan, J.L.³ Weeks, K.M.⁴

47
- 0034619877
- D.K. Worthylake, K.L. Rossman, and J. Sondek Nature 408 2000 682
- (2000) Nature , vol.408 , pp. 682
- Worthylake, D.K.¹ Rossman, K.L.² Sondek, J.³

48
- 33646567148
- A. Whitty, and G. Kumaravel Nat. Chem. Biol. 2 2006 112
- (2006) Nat. Chem. Biol. , vol.2 , pp. 112
- Whitty, A.¹ Kumaravel, G.²

49
- 45949104681
- J.E. Chrencik, A. Brooun, H. Zhang, Mathews II, G.L. Hura, S.A. Foster, J.J. Perry, M. Streiff, P. Ramage, H. Widmer, G.M. Bokoch, J. Tainer, G. Weckbecker, and P. Kuhn J. Mol. Biol. 380 2008 828
- (2008) J. Mol. Biol. , vol.380 , pp. 828
- Chrencik, J.E.¹ Brooun, A.² Zhang, H.³ Mathews, I.I.⁴ Hura, G.L.⁵ Foster, S.A.⁶ Perry, J.J.⁷ Streiff, M.⁸ Ramage, P.⁹ Widmer, H.¹⁰ Bokoch, G.M.¹¹ Tainer, J.¹² Weckbecker, G.¹³ Kuhn, P.¹⁴

50
- 0028801195
- C. Klebe, H. Prinz, A. Wittinghofer, and R.S. Goody Biochemistry 34 1995 12543
- (1995) Biochemistry , vol.34 , pp. 12543
- Klebe, C.¹ Prinz, H.² Wittinghofer, A.³ Goody, R.S.⁴

51
- 0032546533
- C. Lenzen, R.H. Cool, H. Prinz, J. Kuhlmann, and A. Wittinghofer Biochemistry 37 1998 7420
- (1998) Biochemistry , vol.37 , pp. 7420
- Lenzen, C.¹ Cool, R.H.² Prinz, H.³ Kuhlmann, J.⁴ Wittinghofer, A.⁵

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