-
1
-
-
84865079081
-
The pro-tein architecture of human secretory vesicles reveals differential regulation ofsignaling molecule secretion by protein kinases
-
Bark SJ, Wegrzyn J, Taupenot L, Ziegler M, O'Connor D, Ma Q, et al. The pro-tein architecture of human secretory vesicles reveals differential regulation ofsignaling molecule secretion by protein kinases. PLoS ONE 2012;7:e41134.
-
(2012)
PLoS ONE
, vol.7
-
-
Bark, S.J.1
Wegrzyn, J.2
Taupenot, L.3
Ziegler, M.4
O'connor, D.5
Ma, Q.6
-
2
-
-
84857642949
-
The toxic A oligomer and Alzheimer'sdisease: An emperor in need of clothes
-
Benilova I, Karran E, De Strooper B. The toxic A oligomer and Alzheimer'sdisease: an emperor in need of clothes. Nat Neurosci 2012;15:349-57.
-
(2012)
Nat Neurosci
, vol.15
, pp. 349-357
-
-
Benilova, I.1
Karran, E.2
De Strooper, B.3
-
3
-
-
79960809092
-
Neuronalactivity regulates the regional vulnerability to amyloid-beta deposition
-
Bero AW, Yan P, Roh JE, Cirrito JR, Stewart FR, Raichle ME, et al. Neuronalactivity regulates the regional vulnerability to amyloid-beta deposition. Nature2011;14:750-8.
-
(2011)
Nature
, vol.14
, pp. 750-758
-
-
Bero, A.W.1
Yan, P.2
Roh, J.E.3
Cirrito, J.R.4
Stewart, F.R.5
Raichle, M.E.6
-
4
-
-
0023463127
-
Constitutive and regulated secretion of proteins
-
Burgess TL, Kelly RB. Constitutive and regulated secretion of proteins. Annu RevCell Biol 1987;3:243-93.
-
(1987)
Annu RevCell Biol
, vol.3
, pp. 243-293
-
-
Burgess, T.L.1
Kelly, R.B.2
-
5
-
-
0022105487
-
The adrenal chromaffin cell
-
Carmichael SW, Winkler H. The adrenal chromaffin cell. Sci Am 1985;253:40-9.
-
(1985)
Sci Am
, vol.253
, pp. 40-49
-
-
Carmichael, S.W.1
Winkler, H.2
-
6
-
-
77953892400
-
Molecular mechanisms of neurodegeneration inAlzheimer's disase
-
Crews L, Masliah E. Molecular mechanisms of neurodegeneration inAlzheimer's disase. Hum Mol Genet 2010;19:R12-20.
-
(2010)
Hum Mol Genet
, vol.19
-
-
Crews, L.1
Masliah, E.2
-
7
-
-
75749137343
-
Chromogranin B gene ablation reduces the catecholminecargo and decelerates exocytosis in chromaffin secretory vesicles
-
Diaz-Vera J, Morales YG, Hernandez-Fernaud JR, Camacho M, Montesinos MS,Calegari F, et al. Chromogranin B gene ablation reduces the catecholminecargo and decelerates exocytosis in chromaffin secretory vesicles. J Neurosci2010;30:950-7.
-
(2010)
J Neurosci
, vol.30
, pp. 950-957
-
-
Diaz-Vera, J.1
Morales, Y.G.2
Hernandez-Fernaud, J.R.3
Camacho, M.4
Montesinos, M.S.5
Calegari, F.6
-
8
-
-
84878586555
-
Why size matters-balancing mitochondrial dynam-ics in Alzheimer's disease
-
Apr 11
-
Duboff B, Feany M, Götz J. Why size matters-balancing mitochondrial dynam-ics in Alzheimer's disease. Trends Neurosci 2013 Apr 11.
-
(2013)
Trends Neurosci
-
-
Duboff, B.1
Feany, M.2
Götz, J.3
-
9
-
-
0029821729
-
Cholinergic agonists stimulate secretion of soluble full-length amyloid precur-sor protein in neuroendocrine cells
-
Efthimiopoulos S, Vassilacopoulou D, Rippellino JA, Tezapsidis N, Robakis NK.Cholinergic agonists stimulate secretion of soluble full-length amyloid precur-sor protein in neuroendocrine cells. Proc Natl Acad Sci USA 1996;93:8046-50.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 8046-8050
-
-
Efthimiopoulos, S.1
Vassilacopoulou, D.2
Rippellino, J.A.3
Tezapsidis, N.4
Robakis, N.K.5
-
10
-
-
84867508405
-
Probing and trapping a sensitive conformation: Amyloid-fibrils,oligomers, and dimers
-
Fawver JN, Duong KT, Wise-Scira O, Petrofes Chapa R, Schall HE, CoskunerO, et al. Probing and trapping a sensitive conformation: amyloid-fibrils,oligomers, and dimers. J Alzheimers Dis 2012;32:197-215.
-
(2012)
J Alzheimers Dis
, vol.32
, pp. 197-215
-
-
Fawver, J.N.1
Duong, K.T.2
Wise-Scira, O.3
Petrofes Chapa, R.4
Schall, H.E.5
Coskuner, O.6
-
11
-
-
0031848563
-
Divergence and convergence in regulated exocytosis: Thecharacteristics of cAMP-dependent enzyme secretion of parotid salivary acinarcells
-
Fujita-Yoshigaki J. Divergence and convergence in regulated exocytosis: thecharacteristics of cAMP-dependent enzyme secretion of parotid salivary acinarcells. Cell Signal 1998;10:371-5.
-
(1998)
Cell Signal
, vol.10
, pp. 371-375
-
-
Fujita-Yoshigaki, J.1
-
12
-
-
84860851552
-
Humancathepsin v protease participates in production of enkephalin and NPY neu-ropeptide neurotransmitters
-
Funkelstein L, Lu WD, Koch B, Mosier C, Toneff T, Taupenot L, et al. Humancathepsin V protease participates in production of enkephalin and NPY neu-ropeptide neurotransmitters. J Biol Chem 2012;287:15232-41.
-
(2012)
J Biol Chem
, vol.287
, pp. 15232-15241
-
-
Funkelstein, L.1
Lu, W.D.2
Koch, B.3
Mosier, C.4
Toneff, T.5
Taupenot, L.6
-
13
-
-
0347506014
-
Molecular and cellular basis for anti-amyloidtherapy in Alzheimer's disease
-
Gandy S, Martins RN, Buxbaum J. Molecular and cellular basis for anti-amyloidtherapy in Alzheimer's disease. Alzheimer Dis Assoc Disord 2003;17:259-66.
-
(2003)
Alzheimer Dis Assoc Disord
, vol.17
, pp. 259-266
-
-
Gandy, S.1
Martins, R.N.2
Buxbaum, J.3
-
14
-
-
84867797446
-
Especially apolipoprotein E4, increases the oligomerization of amyloid pep-tide
-
Hashimoto T, Serrano-Pozo A, Hori Y, Adams KW, Takeda S, Banerji AO, et al.especially apolipoprotein E4, increases the oligomerization of amyloid pep-tide. J Neurosci 2012;32:15181-92.
-
(2012)
J Neurosci
, vol.32
, pp. 15181-15192
-
-
Hashimoto, T.1
Serrano-Pozo, A.2
Hori, Y.3
Adams, K.W.4
Takeda, S.5
Banerji, A.O.6
-
15
-
-
26844559355
-
Inhibition of cathepsin B reduces amyloid production in regulated secretoryvesicles of neuronal chromaffin cells: Evidence for cathepsin B as a candidate-eta-secretase of Alzheimer's disease
-
Hook V, Toneff T, Bogyo M, Greenbaum D, Medzihradszky KF, Neveu J, et al.Inhibition of cathepsin B reduces amyloid production in regulated secretoryvesicles of neuronal chromaffin cells: evidence for cathepsin B as a candidate-eta-secretase of Alzheimer's disease. Biol Chem 2005;386:931-40.
-
(2005)
Biol Chem
, vol.386
, pp. 931-940
-
-
Hook, V.1
Toneff, T.2
Bogyo, M.3
Greenbaum, D.4
Medzihradszky, K.F.5
Neveu, J.6
-
16
-
-
41149103075
-
Proteases forprocessing proneuropeptides into peptide neurotransmitters and hormones
-
Hook V, Funkelstein L, Lu D, Bark S, Wegrzyn J, Hwang SR. Proteases forprocessing proneuropeptides into peptide neurotransmitters and hormones.Annu Rev Pharmacol Toxicol 2008;48:393-423.
-
(2008)
Annu Rev Pharmacol Toxicol
, vol.48
, pp. 393-423
-
-
Hook, V.1
Funkelstein, L.2
Lu, D.3
Bark, S.4
Wegrzyn, J.5
Hwang, S.R.6
-
17
-
-
67649656100
-
Genetic cathepsin B deficiencyreduces beta-amyloid in transgenic mice expressing human wild-type amyloidprecursor protein
-
Hook V, Kindy M, Reinheckel T, Peters C, Hook G. Genetic cathepsin B deficiencyreduces beta-amyloid in transgenic mice expressing human wild-type amyloidprecursor protein. Biochem Biophys Res Commun 2009;386:284-8.
-
(2009)
Biochem Biophys Res Commun
, vol.386
, pp. 284-288
-
-
Hook, V.1
Kindy, M.2
Reinheckel, T.3
Peters, C.4
Hook, G.5
-
18
-
-
84863337843
-
Alzheimer mechansims and therapeutic strategies
-
Huang Y, Mucke L. Alzheimer mechansims and therapeutic strategies. Cell2012;16:1204-22.
-
(2012)
Cell
, vol.16
, pp. 1204-1222
-
-
Huang, Y.1
Mucke, L.2
-
19
-
-
0032577677
-
Regulation of amyloid precursorprotein secretion by glutamate receptors in human Ntera 2 neurons
-
Jolly-Tornetta C, Gao ZY, Lee VM, Wolf BA. Regulation of amyloid precursorprotein secretion by glutamate receptors in human Ntera 2 neurons. J Biol Chem1998;272:140015-21.
-
(1998)
J Biol Chem
, vol.272
, pp. 140015-140021
-
-
Jolly-Tornetta, C.1
Gao, Z.Y.2
Lee, V.M.3
Wolf, B.A.4
-
20
-
-
0344672942
-
APPprocessing and synaptic function
-
Kamenetz F, Tomita T, Hsieh H, Seabrok G, Borchelt D, Iwatsubo T, et al. APPprocessing and synaptic function. Neuron 2003;37:925-37.
-
(2003)
Neuron
, vol.37
, pp. 925-937
-
-
Kamenetz, F.1
Tomita, T.2
Hsieh, H.3
Seabrok, G.4
Borchelt, D.5
Iwatsubo, T.6
-
21
-
-
84655166490
-
Identification and biology of beta-secretase
-
Kandelepas PC, Vassar R. Identification and biology of beta-secretase. J Neu-rochem 2012;1:55-61.
-
(2012)
J Neu-rochem
, vol.1
, pp. 55-61
-
-
Kandelepas, P.C.1
Vassar, R.2
-
22
-
-
77949669251
-
Group II metabotropic glutamate receptor stimulation triggers production andrelease of Alzheimer's amyloid beta42 from isolated intact nerve terminals
-
Kim SH, Fraser PE, Westaway D, St George-Hyslop PH, Ehrlich M, Gandy S.Group II metabotropic glutamate receptor stimulation triggers production andrelease of Alzheimer's amyloid beta42 from isolated intact nerve terminals. JNeurosci 2010;30:3870-5.
-
(2010)
JNeurosci
, vol.30
, pp. 3870-3875
-
-
Kim, S.H.1
Fraser, P.E.2
Westaway, D.3
St George-Hyslop, P.H.4
Ehrlich, M.5
Gandy, S.6
-
23
-
-
0038652102
-
Gamma-secretase is a membrane protein complex comprised of presenilin, nicastrin,Aph-1, and Pen-2
-
Kimberly WT, LaVoie MJ, Ostaszewski BL, Ye W, Wolfe MS, Selkoe DJ. Gamma-secretase is a membrane protein complex comprised of presenilin, nicastrin,Aph-1, and Pen-2. Proc Natl Acad Sci USA 2003;100:6382-7.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 6382-6387
-
-
Kimberly, W.T.1
Lavoie, M.J.2
Ostaszewski, B.L.3
Ye, W.4
Wolfe, M.S.5
Selkoe, D.J.6
-
24
-
-
0000792598
-
The transmembraneaspartates in presenilin 1 and 2 are obligatory for gamma-secretase activityand amyloid beta-protein generation
-
Kimberly WT, Xia W, Rahmati T, Wolfe MS, Selkoe DJ. The transmembraneaspartates in presenilin 1 and 2 are obligatory for gamma-secretase activityand amyloid beta-protein generation. J Biol Chem 2000;275:3173-8.
-
(2000)
J Biol Chem
, vol.275
, pp. 3173-3178
-
-
Kimberly, W.T.1
Xia, W.2
Rahmati, T.3
Wolfe, M.S.4
Selkoe, D.J.5
-
25
-
-
84860156823
-
Deletion of the cathepsinB gene improves memory deficits in a transgenic Alzheimer's disease mousemodel expressing APP containing the wild-type beta-secretase site sequence
-
Kindy M, Yu J, Zhu H, El-Amouri SS, Hook V, Hook GR. Deletion of the cathepsinB gene improves memory deficits in a transgenic Alzheimer's disease mousemodel expressing APP containing the wild-type beta-secretase site sequence.J Alzheimers Dis 2012;29:827-40.
-
(2012)
J Alzheimers Dis
, vol.29
, pp. 827-840
-
-
Kindy, M.1
Yu, J.2
Zhu, H.3
El-Amouri, S.S.4
Hook, V.5
Hook, G.R.6
-
27
-
-
77956392552
-
ADAM10is the physiologically relevant, constitutive alpha-secretase of the amyloid pre-cursor protein in primary neurons
-
Kuhn PH, Wang H, Dislich B, Colombo A, Zeitschel U, Ellwart JW, et al. ADAM10is the physiologically relevant, constitutive alpha-secretase of the amyloid pre-cursor protein in primary neurons. EMBO J 2010;29:3020-32.
-
(2010)
EMBO J
, vol.29
, pp. 3020-3032
-
-
Kuhn, P.H.1
Wang, H.2
Dislich, B.3
Colombo, A.4
Zeitschel, U.5
Ellwart, J.W.6
-
28
-
-
84869014029
-
Secretase-derived C-terminal fragment of APP, C99, but not A, isa key contributor to early intraneuronal lesions in triple-transgenic mousehippocampus
-
Lauritzen I, Pardossi-Piquard R, Bauer C, Brigham E, Abraham JD, Ranaldi S,et al. secretase-derived C-terminal fragment of APP, C99, but not A, isa key contributor to early intraneuronal lesions in triple-transgenic mousehippocampus. J Neurosci 2012;32:16243-55.
-
(2012)
J Neurosci
, vol.32
, pp. 16243-16255
-
-
Lauritzen, I.1
Pardossi-Piquard, R.2
Bauer, C.3
Brigham, E.4
Abraham, J.D.5
Ranaldi, S.6
-
29
-
-
0037160063
-
Mammalian APH-1 interacts withpresenilin and nicastrin and is required for intramembrane proteolysis ofamyloid-beta precursor protein and Notch
-
Lee SF, Shah S, Li H, Yu C, Han W, Yu G. Mammalian APH-1 interacts withpresenilin and nicastrin and is required for intramembrane proteolysis ofamyloid-beta precursor protein and Notch. J Biol Chem 2002;277:45013-9.
-
(2002)
J Biol Chem
, vol.277
, pp. 45013-45019
-
-
Lee, S.F.1
Shah, S.2
Li, H.3
Yu, C.4
Han, W.5
Yu, G.6
-
30
-
-
84875030047
-
Age-dependent neuroplasticity mechanisms in Alzheimer Tg2576 mice followingmodulation of brain amyloid-levels
-
Lilja AM, Röjdner J, Mustafiz T, Thomé CM, Storelli E, Gonzalez D, et al. Age-dependent neuroplasticity mechanisms in Alzheimer Tg2576 mice followingmodulation of brain amyloid-levels. PLoS ONE 2013;8:e58752.
-
(2013)
PLoS ONE
, vol.8
-
-
Lilja, A.M.1
Röjdner, J.2
Mustafiz, T.3
Thomé, C.M.4
Storelli, E.5
Gonzalez, D.6
-
31
-
-
0003422388
-
-
fifth ed. New York: W. H. Freeman and Company
-
Lodish H, Berk A, Matsudaira P, Kaiser CA, Krieger M, Scott MP, et al. Molecularcell biology. fifth ed. New York: W. H. Freeman and Company; 2004. p. 701-42.
-
(2004)
Molecularcell Biology
, pp. 701-742
-
-
Lodish, H.1
Berk, A.2
Matsudaira, P.3
Kaiser, C.A.4
Krieger, M.5
Scott, M.P.6
-
32
-
-
0037424275
-
PEN-2 and APH-1 coordinatelyregulate proteolytic processing of presenilin 1
-
Luo WJ, Wang H, Li H, Kim BS, Shah S, Lee HJ, et al. PEN-2 and APH-1 coordinatelyregulate proteolytic processing of presenilin 1. J Biol Chem 2003;278:7850-4.
-
(2003)
J Biol Chem
, vol.278
, pp. 7850-7854
-
-
Luo, W.J.1
Wang, H.2
Li, H.3
Kim, B.S.4
Shah, S.5
Lee, H.J.6
-
33
-
-
6944221313
-
The catecholamine release-inhibitory catestatin fragment of chromogranin A: Naturally occurring human variants with different potencies for multiple chro-maffin cell nicotinic cholinergic responses
-
Mahata SK, Mahata M, Wen G, Wong WB, Mahapatra NR, Hamilton BA, et al.The catecholamine release-inhibitory catestatin fragment of chromogranin A:naturally occurring human variants with different potencies for multiple chro-maffin cell nicotinic cholinergic responses. Mol Pharmacol 2004;66:180-191.
-
(2004)
Mol Pharmacol
, vol.66
, pp. 180-191
-
-
Mahata, S.K.1
Mahata, M.2
Wen, G.3
Wong, W.B.4
Mahapatra, N.R.5
Hamilton, B.A.6
-
34
-
-
80052538857
-
Aging and amyloid beta-induced oxidative DNA damageand mitochondrial dysfunction in Alzheimer's disease: Implications for earlyintervention and therapeutics
-
Mao P, Reddy PH. Aging and amyloid beta-induced oxidative DNA damageand mitochondrial dysfunction in Alzheimer's disease: implications for earlyintervention and therapeutics. Biochim Biophys Acta 2011;1812:1359-70.
-
(2011)
Biochim Biophys Acta
, vol.1812
, pp. 1359-1370
-
-
Mao, P.1
Reddy, P.H.2
-
35
-
-
20444440369
-
Metals and amyloid-beta inAlzheimer's disease
-
Maynard CJ, Bush AI, Masters CL, Cappai R, Li QX. Metals and amyloid-beta inAlzheimer's disease. Int J Exp Pathol 2005;86:147-59.
-
(2005)
Int J Exp Pathol
, vol.86
, pp. 147-159
-
-
Maynard, C.J.1
Bush, A.I.2
Masters, C.L.3
Cappai, R.4
Li, Q.X.5
-
36
-
-
0032590054
-
Sol-uble pool of Abeta amyloid as a determinant of severity of neurodegenerationin Alzheimer's disease
-
McLean CA, Cherny RA, Fraser FW, Fuller SJ, Smith MJ, Beyreuther K, et al. Sol-uble pool of Abeta amyloid as a determinant of severity of neurodegenerationin Alzheimer's disease. Ann Neurol 1999;46:860-6.
-
(1999)
Ann Neurol
, vol.46
, pp. 860-866
-
-
McLean, C.A.1
Cherny, R.A.2
Fraser, F.W.3
Fuller, S.J.4
Smith, M.J.5
Beyreuther, K.6
-
37
-
-
0027209083
-
Release of amyloid beta-proteinprecursor derivatives by electrical depolarization of rat hippocampal slices
-
Nitsch RJ, Farber S, Growdon JH, Wurtman RJ. Release of amyloid beta-proteinprecursor derivatives by electrical depolarization of rat hippocampal slices.Proc Natl Acad Sci USA 1993;90:5191-3.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 5191-5193
-
-
Nitsch, R.J.1
Farber, S.2
Growdon, J.H.3
Wurtman, R.J.4
-
38
-
-
0026476297
-
Release of Alzheimer's amy-loid precursor derivatives by activation of muscarinic acetylcholine receptors
-
Nitsch RM, Slack BE, Wurtman RJ, Growdon JH. Release of Alzheimer's amy-loid precursor derivatives by activation of muscarinic acetylcholine receptors.Science 1992;258:304-7.
-
(1992)
Science
, vol.258
, pp. 304-307
-
-
Nitsch, R.M.1
Slack, B.E.2
Wurtman, R.J.3
Growdon, J.H.4
-
39
-
-
0021838132
-
The chromaffin vesicle: A model secretoryorganelle
-
Njus D, Kelley PM, Harnadek GJ. The chromaffin vesicle: a model secretoryorganelle. Physiologist 1985;28:235-41.
-
(1985)
Physiologist
, vol.28
, pp. 235-241
-
-
Njus, D.1
Kelley, P.M.2
Harnadek, G.J.3
-
40
-
-
34250357314
-
Primary cultureof bovine chromaffin cells
-
O'Connor DT, Mahata S, Mahata M, Jiang Q, Hook V, Taupenot L. Primary cultureof bovine chromaffin cells. Nat Protoc 2007;2:1248-53.
-
(2007)
Nat Protoc
, vol.2
, pp. 1248-1253
-
-
O'connor, D.T.1
Mahata, S.2
Mahata, M.3
Jiang, Q.4
Hook, V.5
Taupenot, L.6
-
41
-
-
67649183815
-
Short-term plasticity of small synaptic vesicle (SSV) and largedense core vesicle (LDCV) exocytosis
-
Park Y, Kim KT. Short-term plasticity of small synaptic vesicle (SSV) and largedense core vesicle (LDCV) exocytosis. Cellular signaling 2009;21:1465-70.
-
(2009)
Cellular Signaling
, vol.21
, pp. 1465-1470
-
-
Park, Y.1
Kim, K.T.2
-
42
-
-
85047690140
-
Adisintegrin-metalloproteinase prevents amyloid plaque formation and hip-pocampal defects in an Alzheimer disease mouse model
-
Postina R, Schroeder A, Dewachter I, Bohl J, Schmitt U, Kojro E, et al. Adisintegrin-metalloproteinase prevents amyloid plaque formation and hip-pocampal defects in an Alzheimer disease mouse model. J Clin Invest2004;113:1456-64.
-
(2004)
J Clin Invest
, vol.113
, pp. 1456-1464
-
-
Postina, R.1
Schroeder, A.2
Dewachter, I.3
Bohl, J.4
Schmitt, U.5
Kojro, E.6
-
43
-
-
77955089126
-
The functional neu-rophysiology of the amyloid precursor protein (APP) processing pathway
-
Randall AD, Witton J, Booth C, Hynes-Allen A, Brown JT. The functional neu-rophysiology of the amyloid precursor protein (APP) processing pathway.Neuropharmacology 2010;59:243-67.
-
(2010)
Neuropharmacology
, vol.59
, pp. 243-267
-
-
Randall, A.D.1
Witton, J.2
Booth, C.3
Hynes-Allen, A.4
Brown, J.T.5
-
44
-
-
84655164280
-
The role of met-allobiology and amyloid-peptides in Alzheimer's disease
-
Roberts BR, Ryan TM, Bush AI, Masters CL, Duce JA. The role of met-allobiology and amyloid-peptides in Alzheimer's disease. J Neurochem2012;120:149-66.
-
(2012)
J Neurochem
, vol.120
, pp. 149-166
-
-
Roberts, B.R.1
Ryan, T.M.2
Bush, A.I.3
Masters, C.L.4
Duce, J.A.5
-
45
-
-
80355142815
-
SDS-PAGE/immunoblot detectionof A multimers in human cortical tissue homogenates using antigen-epitoperetrieval
-
Rosen RF, Tomidokoro Y, Ghiso J, Walker LC. SDS-PAGE/immunoblot detectionof A multimers in human cortical tissue homogenates using antigen-epitoperetrieval. J Vis Exp 2010;38 http://www.jove.com/details/php?id= 1916
-
(2010)
J Vis Exp
, vol.38
-
-
Rosen, R.F.1
Tomidokoro, Y.2
Ghiso, J.3
Walker, L.C.4
-
46
-
-
20444377320
-
Galanin impairs performance on learning and memory tasks: Findings fromgalanin transgenic and GAL-R1 knockout mice
-
Rustay NR, Wrenn CC, Kinney JW, Holmes A, Bailey KR, Sullivan TL, et al.Galanin impairs performance on learning and memory tasks: findings fromgalanin transgenic and GAL-R1 knockout mice. Neuropeptides 2005;39:239-43.
-
(2005)
Neuropeptides
, vol.39
, pp. 239-243
-
-
Rustay, N.R.1
Wrenn, C.C.2
Kinney, J.W.3
Holmes, A.4
Bailey, K.R.5
Sullivan, T.L.6
-
47
-
-
38549086800
-
Nicotinic acetylcholine receptors of adrenal chromaf-fin cells
-
Sala F, Nistri A, Criado M. Nicotinic acetylcholine receptors of adrenal chromaf-fin cells. Acta Physiol 2008;192:203-12.
-
(2008)
Acta Physiol
, vol.192
, pp. 203-212
-
-
Sala, F.1
Nistri, A.2
Criado, M.3
-
48
-
-
33750991103
-
Over-expression of two dif-ferent forms of the alpha-secretase ADAM10 affects learning and memory inmice
-
Schmitt U, Hiemke C, Fahrenholz F, Schroeder A. Over-expression of two dif-ferent forms of the alpha-secretase ADAM10 affects learning and memory inmice. Behav Brain Res 2006;175:278-84.
-
(2006)
Behav Brain Res
, vol.175
, pp. 278-284
-
-
Schmitt, U.1
Hiemke, C.2
Fahrenholz, F.3
Schroeder, A.4
-
49
-
-
0020682114
-
Structure-activity rela-tionships for activation of adenylate cyclase by the diterpene forskolin and itsderivatives
-
Seamon KB, Daly JW, Metzger H, de Souza NJ, Reden J. Structure-activity rela-tionships for activation of adenylate cyclase by the diterpene forskolin and itsderivatives. J Med Chem 1983;26:436-9.
-
(1983)
J Med Chem
, vol.26
, pp. 436-439
-
-
Seamon, K.B.1
Daly, J.W.2
Metzger, H.3
De Souza, N.J.4
Reden, J.5
-
51
-
-
0035066332
-
Alzheimer's disease: Genes, proteins, and therapy
-
Selkoe DJ. Alzheimer's disease: genes, proteins, and therapy. Physiol Rev2001;81:741-66.
-
(2001)
Physiol Rev
, vol.81
, pp. 741-766
-
-
Selkoe, D.J.1
-
52
-
-
0004291972
-
-
sixth ed. Philadelphia: Lippincott-Raven
-
Siegel GJ, Agranoff BS, Albers RW, Fisher SK, Uhler MD. Basic neurochemistry.sixth ed. Philadelphia: Lippincott-Raven; 1999. p. 191-400.
-
(1999)
Basic Neurochemistry
, pp. 191-400
-
-
Siegel, G.J.1
Agranoff, B.S.2
Albers, R.W.3
Fisher, S.K.4
Uhler, M.D.5
-
53
-
-
0032698746
-
Alzheimer's disease: Perspective for the new millennium
-
Sisodia SS. Alzheimer's disease: perspective for the new millennium. J ClinInvest 1999;104:1169-70.
-
(1999)
J ClinInvest
, vol.104
, pp. 1169-1170
-
-
Sisodia, S.S.1
-
54
-
-
0014088708
-
A simple method for the isolation of adrenal chromaffingranules on a large scale
-
Smith AD, Winkler H. A simple method for the isolation of adrenal chromaffingranules on a large scale. Biochem J 1967;103:480-2.
-
(1967)
Biochem J
, vol.103
, pp. 480-482
-
-
Smith, A.D.1
Winkler, H.2
-
55
-
-
0037579059
-
-
third ed. Amsterdam: Elsevier
-
Squire L, Berg D, Bloom F, Du Lac S, Ghosh A, Spitzer N. Fundamental neuro-science. third ed. Amsterdam: Elsevier; 2008. p. 41-271.
-
(2008)
Fundamental Neuro-science
, pp. 41-271
-
-
Squire, L.1
Berg, D.2
Bloom, F.3
Du Lac, S.4
Ghosh, A.5
Spitzer, N.6
-
56
-
-
0035957386
-
Galanintransgenic mice display cognitive and neurochemical deficits characteristic ofAlzheimer's disease
-
Steiner RA, Hohmann JG, Holmes A, Wrenn CC, Cadd G, Juréus A, et al. Galanintransgenic mice display cognitive and neurochemical deficits characteristic ofAlzheimer's disease. Proc Natl Acad Sci USA 2001;98:4184-9.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 4184-4189
-
-
Steiner, R.A.1
Hohmann, J.G.2
Holmes, A.3
Wrenn, C.C.4
Cadd, G.5
Juréus, A.6
-
57
-
-
0032477747
-
Release of nontransmembrane full-length Alzheimer's amyloidprecursor protein from the lumenar surface of chromaffin granule membranes
-
Tezapsidis N, Li HC, Ripellino JA, Efthimiopoulos S, Vassilacopoulou D, Samba-murti K, et al. Release of nontransmembrane full-length Alzheimer's amyloidprecursor protein from the lumenar surface of chromaffin granule membranes.Biochemistry 1998;37:1274-82.
-
(1998)
Biochemistry
, vol.37
, pp. 1274-1282
-
-
Tezapsidis, N.1
Li, H.C.2
Ripellino, J.A.3
Efthimiopoulos, S.4
Vassilacopoulou, D.5
Samba-Murti, K.6
-
58
-
-
15844425969
-
Endo-proteolysis of presenilin 1 and accumulation of processed derivatives in vivo
-
Thinakaran G, Borchelt DR, Lee MK, Slunt HH, Spitzer L, Kim G, et al. Endo-proteolysis of presenilin 1 and accumulation of processed derivatives in vivo.Neuron 1996;17:181-90.
-
(1996)
Neuron
, vol.17
, pp. 181-190
-
-
Thinakaran, G.1
Borchelt, D.R.2
Lee, M.K.3
Slunt, H.H.4
Spitzer, L.5
Kim, G.6
-
59
-
-
70350455062
-
The beta-secretase enzyme BACE inhealth and Alzheimer's disease: Regulation, cell biology, function, and thera-peutic potential
-
Vassar R, Kovacs DM, Uan R, Wong PC. The beta-secretase enzyme BACE inhealth and Alzheimer's disease: regulation, cell biology, function, and thera-peutic potential. J Neurosci 2009;29:12787-94.
-
(2009)
J Neurosci
, vol.29
, pp. 12787-12794
-
-
Vassar, R.1
Kovacs, D.M.2
Uan, R.3
Wong, P.C.4
-
60
-
-
0028929324
-
Full-length and truncated Alzheimer amyloid precursors in chromaffin granules: Solubilization of membrane amyloid precursor is mediated by an enzymaticmechanism
-
Vassilacopoulou D, Ripellino JA, Tezapsidis N, Hook VYH, Robakis NK. Full-length and truncated Alzheimer amyloid precursors in chromaffin granules:solubilization of membrane amyloid precursor is mediated by an enzymaticmechanism. J Neurochem 1995;64:2140-6.
-
(1995)
J Neurochem
, vol.64
, pp. 2140-2146
-
-
Vassilacopoulou, D.1
Ripellino, J.A.2
Tezapsidis, N.3
Hook, V.Y.H.4
Robakis, N.K.5
-
61
-
-
0034609516
-
The oligomerization ofamyloid beta-protein begins intracellularly in cells derived from human brain
-
Walsh DM, Tseng BP, Rydel RE, Podlisny MB, Selkoe DJ. The oligomerization ofamyloid beta-protein begins intracellularly in cells derived from human brain.Biochemistry 2000;39:10831-9.
-
(2000)
Biochemistry
, vol.39
, pp. 10831-10839
-
-
Walsh, D.M.1
Tseng, B.P.2
Rydel, R.E.3
Podlisny, M.B.4
Selkoe, D.J.5
-
62
-
-
34249295158
-
Proteomics of neuroen-docrine secretory vesicles reveal distinct functional systems for biosynthesisand exocytosis of peptide hormones and neurotransmitters
-
Wegrzyn J, Lee J, Neveu JM, Lane WS, Hook V. Proteomics of neuroen-docrine secretory vesicles reveal distinct functional systems for biosynthesisand exocytosis of peptide hormones and neurotransmitters. J Proteome Res2007;6:1652-65.
-
(2007)
J Proteome Res
, vol.6
, pp. 1652-1665
-
-
Wegrzyn, J.1
Lee, J.2
Neveu, J.M.3
Lane, W.S.4
Hook, V.5
-
63
-
-
77957343236
-
Proteomics of dense core secretory vesicles reveal distinct protein categoriesfor secretion of neuroeffectors for cell-cell communication
-
Wegrzyn JL, Bark SJ, Funkelstein L, Mosier CA, Yap A, Kazemi-Esfarjani P, et al.Proteomics of dense core secretory vesicles reveal distinct protein categoriesfor secretion of neuroeffectors for cell-cell communication. J Proteome Res2010;9:5002-24.
-
(2010)
J Proteome Res
, vol.9
, pp. 5002-5024
-
-
Wegrzyn, J.L.1
Bark, S.J.2
Funkelstein, L.3
Mosier, C.A.4
Yap, A.5
Kazemi-Esfarjani, P.6
-
64
-
-
84884211307
-
What's hAPPening at synapses the role of amyloid protein precursor and amyloid in neurological disorders
-
Westmark CJ. What's hAPPening at synapses? The role of amyloid protein precursor and amyloid in neurological disorders. Mol Psychiatry2013;18:425-34.
-
(2013)
Mol Psychiatry
, vol.18
, pp. 425-434
-
-
Westmark, C.J.1
-
65
-
-
0031982551
-
Arginine and lysineaminopeptidase activities in chromaffin granules of bovine adrenalmedulla: Relevance to prohormone processing
-
Yasothornsrikul S, Toneff T, Hwang SR, Hook VYH. Arginine and lysineaminopeptidase activities in chromaffin granules of bovine adrenalmedulla: relevance to prohormone processing. J Neurochem 1998;70:153-63.
-
(1998)
J Neurochem
, vol.70
, pp. 153-163
-
-
Yasothornsrikul, S.1
Toneff, T.2
Hwang, S.R.3
Hook, V.Y.H.4
-
66
-
-
0042924384
-
Cathepsin L in secretory vesicles functions as a prohormone- processingenzyme for production of the enkephalin peptide neurotransmitter
-
Yasothornsrikul S, Greenbaum D, Medzihradszky KF, Toneff T, Bundey R, MillerR, et al. Cathepsin L in secretory vesicles functions as a prohormone-processingenzyme for production of the enkephalin peptide neurotransmitter. Proc NatlAcad Sci U S A 2003;100:9590-5.
-
(2003)
Proc NatlAcad Sci U S A
, vol.100
, pp. 9590-9595
-
-
Yasothornsrikul, S.1
Greenbaum, D.2
Medzihradszky, K.F.3
Toneff, T.4
Bundey, R.5
Miller, R.6
-
67
-
-
0024268197
-
A sensitive radioenzymatic assay forepinephrine forming enzymes
-
Ziegler MG, Kennedy B, Elayan H. A sensitive radioenzymatic assay forepinephrine forming enzymes. Life Sci 1988;43:2117-22.
-
(1988)
Life Sci
, vol.43
, pp. 2117-2122
-
-
Ziegler, M.G.1
Kennedy, B.2
Elayan, H.3
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