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Volumn 38, Issue 11, 2013, Pages 1159-1171

Differential effects of the estrogen receptor agonist estradiol on toxicity induced by enzymatically-derived or autoxidation-derived oxysterols in human ARPE-19 cells

Author keywords

Age related macular degeneration; Estrogen receptor; IL 6; Liver X receptor; Oxysterols; TNF

Indexed keywords

25 HYDROXYCHOLESTEROL; 26 HYDROXYCHOLESTEROL; 3 [3 [[2 CHLORO 3 (TRIFLUOROMETHYL)BENZYL](2 DIPHENYLETHYL)AMINO]PROPOXY]PHENYLACETIC ACID; 7 OXOCHOLESTEROL; ESTRADIOL; ESTROGEN RECEPTOR; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; FULVESTRANT; INTERLEUKIN 6; INTERLEUKIN 8; LIVER X RECEPTOR; LIVER X RECEPTOR ALPHA; LIVER X RECEPTOR BETA; MONOCYTE CHEMOTACTIC PROTEIN 1; OXYSTEROL; PLATELET DERIVED GROWTH FACTOR; TUMOR NECROSIS FACTOR ALPHA; VASCULOTROPIN;

EID: 84884997331     PISSN: 02713683     EISSN: 14602202     Source Type: Journal    
DOI: 10.3109/02713683.2013.811257     Document Type: Article
Times cited : (8)

References (84)
  • 3
    • 0030027775 scopus 로고    scopus 로고
    • Is the incidence of registrable agerelated macular degeneration increasing?
    • Evans J, Wormald R. Is the incidence of registrable agerelated macular degeneration increasing? Br J Ophthalmol 1996;80:9-14
    • (1996) Br J Ophthalmol , vol.80 , pp. 9-14
    • Evans, J.1    Wormald, R.2
  • 4
    • 77951622411 scopus 로고    scopus 로고
    • The prevalence of age-related macular degeneration in Asians: A systematic review and meta-analysis
    • Kawasaki R, Yasuda M, Song SJ, Chen SJ, Jonas JB,Wang JJ, et al. The prevalence of age-related macular degeneration in Asians: A systematic review and meta-analysis. Ophthalmology 2010;117:921-927
    • (2010) Ophthalmology , vol.117 , pp. 921-927
    • Kawasaki, R.1    Yasuda, M.2    Song, S.J.3    Chen, S.J.4    Jonas, J.B.5    Wang, J.J.6
  • 5
    • 11144355019 scopus 로고    scopus 로고
    • Prevalence of vitreoretinal disorders in a rural population of southern india: The aravind comprehensive eye study
    • Nirmalan PK, Katz J, Robin AL, Tielsch JM, Namperumalsamy P, Kim R, et al. Prevalence of vitreoretinal disorders in a rural population of southern India: The Aravind Comprehensive Eye Study. Arch Ophthalmol 2004;122:581-586
    • (2004) Arch Ophthalmol , vol.122 , pp. 581-586
    • Nirmalan, P.K.1    Katz, J.2    Robin, A.L.3    Tielsch, J.M.4    Namperumalsamy, P.5    Kim, R.6
  • 6
    • 65249101367 scopus 로고    scopus 로고
    • Forecasting age-related macular degeneration through the year 2050: The potential impact of new treatments
    • Rein DB, Wittenborn JS, Zhang X, Honeycutt AA, Lesesne SB, Saaddine J, et al. Forecasting age-related macular degeneration through the year 2050: The potential impact of new treatments. Arch Ophthalmol 2009;127:533-540
    • (2009) Arch Ophthalmol , vol.127 , pp. 533-540
    • Rein, D.B.1    Wittenborn, J.S.2    Zhang, X.3    Honeycutt, A.A.4    Lesesne, S.B.5    Saaddine, J.6
  • 7
    • 0035078715 scopus 로고    scopus 로고
    • Risk factors for age-related macular degeneration: Pooled findings from three continents
    • Smith W, Assink J, Klein R, Mitchell P, Klaver CC, Klein BE, et al. Risk factors for age-related macular degeneration: Pooled findings from three continents. Ophthalmology 2001;108:697-704
    • (2001) Ophthalmology , vol.108 , pp. 697-704
    • Smith, W.1    Assink, J.2    Klein, R.3    Mitchell, P.4    Klaver, C.C.5    Klein, B.E.6
  • 8
    • 21244451958 scopus 로고    scopus 로고
    • The retinal pigment epithelium in visual function
    • Strauss O. The retinal pigment epithelium in visual function. Physiol Rev 2005;85:845-881
    • (2005) Physiol Rev , vol.85 , pp. 845-881
    • Strauss, O.1
  • 10
    • 69249213701 scopus 로고    scopus 로고
    • Esterified cholesterol is highly localized to bruch's membrane, as revealed by lipid histochemistry in wholemounts of human choroid
    • Rudolf M, Curcio CA. Esterified cholesterol is highly localized to Bruch's membrane, as revealed by lipid histochemistry in wholemounts of human choroid. J Histochem Cytochem 2009;57:731-739
    • (2009) J Histochem Cytochem , vol.57 , pp. 731-739
    • Rudolf, M.1    Curcio, C.A.2
  • 11
    • 20444430102 scopus 로고    scopus 로고
    • Basal deposits and drusen in eyes with age-related maculopathy: Evidence for solid lipid particles
    • Curcio CA, Presley JB, Millican CL, Medeiros NE. Basal deposits and drusen in eyes with age-related maculopathy: Evidence for solid lipid particles. Exp Eye Res 2005;80: 761-775
    • (2005) Exp Eye Res , vol.80 , pp. 761-775
    • Curcio, C.A.1    Presley, J.B.2    Millican, C.L.3    Medeiros, N.E.4
  • 12
    • 28444468904 scopus 로고    scopus 로고
    • Esterified and unesterified cholesterol in drusen and basal deposits of eyes with age-related maculopathy
    • Curcio CA, Presley JB, Malek G, Medeiros NE, Avery DV, Kruth HS. Esterified and unesterified cholesterol in drusen and basal deposits of eyes with age-related maculopathy. Exp Eye Res 2005;81:731-741
    • (2005) Exp Eye Res , vol.81 , pp. 731-741
    • Curcio, C.A.1    Presley, J.B.2    Malek, G.3    Medeiros, N.E.4    Avery, D.V.5    Kruth, H.S.6
  • 13
    • 0028349871 scopus 로고
    • Analysis of lipid deposits extracted from human macular and peripheral Bruch's membrane
    • Holz FG, Sheraidah G, Pauleikhoff D, Bird AC. Analysis of lipid deposits extracted from human macular and peripheral Bruch's membrane. Arch Ophthalmol 1994; 112:402-406
    • (1994) Arch Ophthalmol , vol.112 , pp. 402-406
    • Holz, F.G.1    Sheraidah, G.2    Pauleikhoff, D.3    Bird, A.C.4
  • 15
    • 0037332052 scopus 로고    scopus 로고
    • Apolipoprotein B in cholesterol-containing drusen and basal deposits of human eyes with age-related maculopathy
    • Malek G, Li CM, Guidry C, Medeiros NE, Curcio CA. Apolipoprotein B in cholesterol-containing drusen and basal deposits of human eyes with age-related maculopathy. Am J Pathol 2003;162:413-425
    • (2003) Am J Pathol , vol.162 , pp. 413-425
    • Malek, G.1    Li, C.M.2    Guidry, C.3    Medeiros, N.E.4    Curcio, C.A.5
  • 16
    • 33744919301 scopus 로고    scopus 로고
    • A cholesterol-enriched diet induces ultrastructural changes in retinal and macroglial rabbit cells
    • Trivino A, Ramirez AI, Salazar JJ, de HR, Rojas B, Padilla E, et al. A cholesterol-enriched diet induces ultrastructural changes in retinal and macroglial rabbit cells. Exp Eye Res 2006;83:357-366
    • (2006) Exp Eye Res , vol.83 , pp. 357-366
    • Trivino, A.1    Ramirez, A.I.2    Salazar, J.J.3    De, H.R.4    Rojas, B.5    Padilla, E.6
  • 17
    • 65549154386 scopus 로고    scopus 로고
    • The retinal oxysterol pathway: A unifying hypothesis for the cause of age-related macular degeneration
    • Javitt NB, Javitt JC. The retinal oxysterol pathway: A unifying hypothesis for the cause of age-related macular degeneration. Curr Opin Ophthalmol 2009;20:151-157
    • (2009) Curr Opin Ophthalmol , vol.20 , pp. 151-157
    • Javitt, N.B.1    Javitt, J.C.2
  • 18
    • 80051795545 scopus 로고    scopus 로고
    • Cholesterol-enriched diet causes age-related macular degeneration-like pathology in rabbit retina
    • doi: 10.1186/1471-2415-11-22
    • Dasari B, Prasanthi JR, Marwarha G, Singh BB, Ghribi O. Cholesterol-enriched diet causes age-related macular degeneration-like pathology in rabbit retina. BMC Ophthalmol 2011;11:22. doi: 10.1186/1471-2415-11-22
    • (2011) BMC Ophthalmol , vol.11 , pp. 22
    • Dasari, B.1    Prasanthi, J.R.2    Marwarha, G.3    Singh, B.B.4    Ghribi, O.5
  • 19
    • 0035985702 scopus 로고    scopus 로고
    • Oxysterols in human circulation: Which role do they have?
    • Bjorkhem I, Meaney S, Diczfalusy U. Oxysterols in human circulation: Which role do they have? Curr Opin Lipidol 2002;13:247-253
    • (2002) Curr Opin Lipidol , vol.13 , pp. 247-253
    • Bjorkhem, I.1    Meaney, S.2    Diczfalusy, U.3
  • 20
    • 77956494238 scopus 로고    scopus 로고
    • The oxysterol 27-hydroxycholesterol increases beta-amyloid and oxidative stress in retinal pigment epithelial cells
    • doi: 10.1186/1471-2415-10-22
    • Dasari B, Prasanthi J, Marwarha G, Singh B, Ghribi O. The oxysterol 27-hydroxycholesterol increases beta-amyloid and oxidative stress in retinal pigment epithelial cells. BMC Ophthalmol 2010;10:22. doi: 10.1186/1471-2415-10- 22
    • (2010) BMC Ophthalmol , vol.10 , pp. 22
    • Dasari, B.1    Prasanthi, J.2    Marwarha, G.3    Singh, B.4    Ghribi, O.5
  • 21
    • 0035185753 scopus 로고    scopus 로고
    • Oxidized LDL-induced injury and apoptosis in atherosclerosis potential roles for oxysterols
    • Colles SM, Maxson JM, Carlson SG, Chisolm GM. Oxidized LDL-induced injury and apoptosis in atherosclerosis. Potential roles for oxysterols. Trends Cardiovasc Med 2001;11:131-138
    • (2001) Trends Cardiovasc Med , vol.11 , pp. 131-138
    • Colles, S.M.1    Maxson, J.M.2    Carlson, S.G.3    Chisolm, G.M.4
  • 22
    • 78049373374 scopus 로고    scopus 로고
    • Effects of oxysterols on cell viability, inflammatory cytokines, VEGF, and reactive oxygen species production on human retinal cells: Cytoprotective effects and prevention of VEGF secretion by resveratrol
    • Dugas B, Charbonnier S, Baarine M, Ragot K, Delmas D, Ménétrier F, et al. Effects of oxysterols on cell viability, inflammatory cytokines, VEGF, and reactive oxygen species production on human retinal cells: Cytoprotective effects and prevention of VEGF secretion by resveratrol. Eur J Nutr 2010;49:435-446
    • (2010) Eur J Nutr , vol.49 , pp. 435-446
    • Dugas, B.1    Charbonnier, S.2    Baarine, M.3    Ragot, K.4    Delmas, D.5    Ménétrier, F.6
  • 23
    • 59449093828 scopus 로고    scopus 로고
    • 7-Ketocholesterol is present in lipid deposits in the primate retina: Potential implication in the induction of VEGF and CNV formation
    • Moreira EF, Larrayoz IM, Lee JW, Rodriguez IR. 7-Ketocholesterol is present in lipid deposits in the primate retina: Potential implication in the induction of VEGF and CNV formation. Invest Ophthalmol Vis Sci 2009;50: 523-532
    • (2009) Invest Ophthalmol Vis Sci , vol.50 , pp. 523-532
    • Moreira, E.F.1    Larrayoz, I.M.2    Lee, J.W.3    Rodriguez, I.R.4
  • 24
    • 34248218541 scopus 로고    scopus 로고
    • Activation of caspase-8 and caspase-12 pathways by 7-ketocholesterol in human retinal pigment epithelial cells
    • Luthra S, Fardin B, Dong J, Hertzog D, Kamjoo S, Gebremariam S, et al. Activation of caspase-8 and caspase-12 pathways by 7-ketocholesterol in human retinal pigment epithelial cells. Invest Ophthalmol Vis Sci 2006;47: 5569-5575
    • (2006) Invest Ophthalmol Vis Sci , vol.47 , pp. 5569-5575
    • Luthra, S.1    Fardin, B.2    Dong, J.3    Hertzog, D.4    Kamjoo, S.5    Gebremariam, S.6
  • 25
    • 3242881654 scopus 로고    scopus 로고
    • Cytotoxicity of oxidized low-density lipoprotein in cultured rpe cells is dependent on the formation of 7-ketocholesterol
    • Rodriguez IR, Alam S, Lee JW. Cytotoxicity of oxidized low-density lipoprotein in cultured rpe cells is dependent on the formation of 7-ketocholesterol. Invest Ophthalmol Vis Sci 2004;45:2830-2837
    • (2004) Invest Ophthalmol Vis Sci , vol.45 , pp. 2830-2837
    • Rodriguez, I.R.1    Alam, S.2    Lee, J.W.3
  • 27
    • 0035914330 scopus 로고    scopus 로고
    • 27-hydroxycholesterol is an endogenous ligand for liver X receptor in cholesterol-loaded cells
    • Fu X, Menke JG, Chen Y, Zhou G, MacNaul KL,Wright SD, et al. 27-hydroxycholesterol is an endogenous ligand for liver X receptor in cholesterol-loaded cells. J Biol Chem 2001;276:38378-38387
    • (2001) J Biol Chem , vol.276 , pp. 38378-38387
    • Fu, X.1    Menke, J.G.2    Chen, Y.3    Zhou, G.4    Mac Naul, K.L.5    Wright, S.D.6
  • 28
    • 0033714093 scopus 로고    scopus 로고
    • Cholestenoic acid is a naturally occurring ligand for liver X receptor alpha
    • Song C, Liao S. Cholestenoic acid is a naturally occurring ligand for liver X receptor alpha. Endocrinology 2000;141: 4180-4184
    • (2000) Endocrinology , vol.141 , pp. 4180-4184
    • Song, C.1    Liao, S.2
  • 29
    • 58849154028 scopus 로고    scopus 로고
    • Impact of 27-hydroxycholesterol on amyloid-beta peptide production and ATP-binding cassette transporter expression in primary human neurons
    • Kim WS, Chan SL, Hill AF, Guillemin GJ, Garner B. Impact of 27-hydroxycholesterol on amyloid-beta peptide production and ATP-binding cassette transporter expression in primary human neurons. J Alzheimers Dis 2009;16: 121-131
    • (2009) J Alzheimers Dis , vol.16 , pp. 121-131
    • Kim, W.S.1    Chan, S.L.2    Hill, A.F.3    Guillemin, G.J.4    Garner, B.5
  • 30
    • 34948820661 scopus 로고    scopus 로고
    • 27-Hydroxycholesterol is an endogenous SERM that inhibits the cardiovascular effects of estrogen
    • Umetani M, Domoto H, Gormley AK, Yuhanna IS, Cummins CL, Javitt NB, et al. 27-Hydroxycholesterol is an endogenous SERM that inhibits the cardiovascular effects of estrogen. Nat Med 2007;13:1185-1192
    • (2007) Nat Med , vol.13 , pp. 1185-1192
    • Umetani, M.1    Domoto, H.2    Gormley, A.K.3    Yuhanna, I.S.4    Cummins, C.L.5    Javitt, N.B.6
  • 31
    • 79551647461 scopus 로고    scopus 로고
    • The cholesterol metabolite 25-hydroxycholesterol activates estrogen receptor a-mediated signaling in cancer cells and in cardiomyocytes
    • Lappano R, Recchia AG, De Francesco EM, Angelone T, Cerra MC, Picard D, et al. The cholesterol metabolite 25-hydroxycholesterol activates estrogen receptor a-mediated signaling in cancer cells and in cardiomyocytes. PLoS ONE 2011;6:e16631
    • (2011) PLoS ONE , vol.6
    • Lappano, R.1    Recchia, A.G.2    De Francesco, E.M.3    Angelone, T.4    Cerra, M.C.5    Picard, D.6
  • 35
    • 0034332969 scopus 로고    scopus 로고
    • Female sex steroids: Effects upon microglial cell activation
    • Drew PD, Chavis JA. Female sex steroids: Effects upon microglial cell activation. J Neuroimmunol 2000;111:77-85
    • (2000) J Neuroimmunol , vol.111 , pp. 77-85
    • Drew, P.D.1    Chavis, J.A.2
  • 36
    • 10844258008 scopus 로고    scopus 로고
    • Estrogen as a multi-active neuroprotective agent in traumatic injuries
    • Sribnick EA, Ray SK, Banik NL. Estrogen as a multi-active neuroprotective agent in traumatic injuries. Neurochem Res 2004;29:2007-2014
    • (2004) Neurochem Res , vol.29 , pp. 2007-2014
    • Sribnick, E.A.1    Ray, S.K.2    Banik, N.L.3
  • 37
    • 0034904940 scopus 로고    scopus 로고
    • Neurotoxicity of 24-hydroxycholesterol, an important cholesterol elimination product of the brain, may be prevented by vitamin E and estradiol-17beta
    • Kolsch H, Ludwig M, Lutjohann D, Rao ML. Neurotoxicity of 24-hydroxycholesterol, an important cholesterol elimination product of the brain, may be prevented by vitamin E and estradiol-17beta. J Neural Transm 2001;108:475-488
    • (2001) J Neural Transm , vol.108 , pp. 475-488
    • Kolsch, H.1    Ludwig, M.2    Lutjohann, D.3    Rao, M.L.4
  • 38
    • 33845587711 scopus 로고    scopus 로고
    • Enzymatic reduction of oxysterols impairs LXR signaling in cultured cells and the livers of mice
    • Chen W, Chen G, Head DL, Mangelsdorf DJ, Russell DW. Enzymatic reduction of oxysterols impairs LXR signaling in cultured cells and the livers of mice. Cell Metab 2007;5: 73-79
    • (2007) Cell Metab , vol.5 , pp. 73-79
    • Chen, W.1    Chen, G.2    Head, D.L.3    Mangelsdorf, D.J.4    Russell, D.W.5
  • 39
    • 0029805887 scopus 로고    scopus 로고
    • An oxysterol signalling pathway mediated by the nuclear receptor LXR[alpha
    • Janowski BA, Willy PJ, Devi TR, Falck JR, Mangelsdorf DJ. An oxysterol signalling pathway mediated by the nuclear receptor LXR[alpha]. Nature 1996;383:728-731
    • (1996) Nature , vol.383 , pp. 728-731
    • Janowski, B.A.1    Willy, P.J.2    Devi, T.R.3    Falck, J.R.4    Mangelsdorf, D.J.5
  • 41
    • 0025806764 scopus 로고
    • Intracellular heterogeneity in mitochondrial membrane potentials revealed by a J-aggregateforming lipophilic cation JC-1
    • Smiley ST, Reers M, Mottola-Hartshorn C, Lin M, Chen A, Smith TW, et al. Intracellular heterogeneity in mitochondrial membrane potentials revealed by a J-aggregateforming lipophilic cation JC-1. Proc Natl Acad Sci U S A 1991;88:3671-3675
    • (1991) Proc Natl Acad Sci U S A , vol.88 , pp. 3671-3675
    • Smiley, S.T.1    Reers, M.2    Mottola-Hartshorn, C.3    Lin, M.4    Chen, A.5    Smith, T.W.6
  • 42
    • 0027374638 scopus 로고
    • A new method for the cytofluorimetric analysis of mitochondrial membrane potential using the Jaggregate forming lipophilic cation 5,5',6,6'-tetrachloro- 1,1',3,3'-tetraethylbenzimidazolcarbocyanine iodide (JC-1
    • Cossarizza A, Baccarani-Contri M, Kalashnikova G, Franceschi C. A new method for the cytofluorimetric analysis of mitochondrial membrane potential using the Jaggregate forming lipophilic cation 5,5',6,6'-tetrachloro- 1,1',3,3'-tetraethylbenzimidazolcarbocyanine iodide (JC-1). Biochem Biophys Res Commun 1993;197:40-45
    • (1993) Biochem Biophys Res Commun , vol.197 , pp. 40-45
    • Cossarizza, A.1    Baccarani-Contri, M.2    Kalashnikova, G.3    Franceschi, C.4
  • 45
    • 79951715828 scopus 로고    scopus 로고
    • Research resource: Nuclear receptor atlas of human retinal pigment epithelial cells: Potential relevance to agerelated macular degeneration
    • Dwyer MA, Kazmin D, Hu P, McDonnell DP, Malek G. Research resource: Nuclear receptor atlas of human retinal pigment epithelial cells: Potential relevance to agerelated macular degeneration. Mol Endocrinol 2011;25: 360-372
    • (2011) Mol Endocrinol , vol.25 , pp. 360-372
    • Dwyer, M.A.1    Kazmin, D.2    Hu, P.3    McDonnell, D.P.4    Malek, G.5
  • 46
    • 77953809809 scopus 로고    scopus 로고
    • Influence of selective estrogen receptor modulators on interleukin-6 expression in human retinal pigment epithelial cells (ARPE-19
    • Paimela T, Hyttinen JM, Viiri J, Ryhanen T, Karvonen MK, Unkila M, et al. Influence of selective estrogen receptor modulators on interleukin-6 expression in human retinal pigment epithelial cells (ARPE-19). Eur J Pharmacol 2010; 640:219-225
    • (2010) Eur J Pharmacol , vol.640 , pp. 219-225
    • Paimela, T.1    Hyttinen, J.M.2    Viiri, J.3    Ryhanen, T.4    Karvonen, M.K.5    Unkila, M.6
  • 47
    • 0034672672 scopus 로고    scopus 로고
    • Oxysterol biosynthetic enzymes
    • Russell DW. Oxysterol biosynthetic enzymes. Biochim Biophys Acta 2000;1529:126-135
    • (2000) Biochim Biophys Acta , vol.1529 , pp. 126-135
    • Russell, D.W.1
  • 49
    • 0032890337 scopus 로고    scopus 로고
    • Oxysterols and atherosclerosis
    • Brown AJ, Jessup W. Oxysterols and atherosclerosis. Atherosclerosis 1999;142:1-28
    • (1999) Atherosclerosis , vol.142 , pp. 1-28
    • Brown, A.J.1    Jessup, W.2
  • 50
    • 0027457242 scopus 로고
    • 24-, 25- and 27-hydroxylation of cholesterol by a purified preparation of 27-hydroxylase from pig liver
    • Lund E, Bjorkhem I, Furster C, Wikvall K. 24-, 25- and 27-hydroxylation of cholesterol by a purified preparation of 27-hydroxylase from pig liver. Biochim Biophys Acta 1993;1166:177-182
    • (1993) Biochim Biophys Acta , vol.1166 , pp. 177-182
    • Lund, E.1    Bjorkhem, I.2    Furster, C.3    Wikvall, K.4
  • 51
    • 0033594903 scopus 로고    scopus 로고
    • CDNA cloning of cholesterol 24-hydroxylase, a mediator of cholesterol homeostasis in the brain
    • Lund EG, Guileyardo JM, Russell DW. cDNA cloning of cholesterol 24-hydroxylase, a mediator of cholesterol homeostasis in the brain. Proc Natl Acad Sci U S A 1999;96: 7238-7243
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 7238-7243
    • Lund, E.G.1    Guileyardo, J.M.2    Russell, D.W.3
  • 52
    • 33947324152 scopus 로고    scopus 로고
    • Cholesterol-24S-hydroxylase (CYP46A1) is specifically expressed in neurons of the neural retina
    • Bretillon L, Diczfalusy U, Bjorkhem I, Maire MA, Martine L, Joffre C, et al. Cholesterol-24S-hydroxylase (CYP46A1) is specifically expressed in neurons of the neural retina. Curr Eye Res 2007;32:361-366
    • (2007) Curr Eye Res , vol.32 , pp. 361-366
    • Bretillon, L.1    Diczfalusy, U.2    Bjorkhem, I.3    Maire, M.A.4    Martine, L.5    Joffre, C.6
  • 53
    • 33744904197 scopus 로고    scopus 로고
    • Expression and localization of sterol 27-hydroxylase (CYP27A1) in monkey retina
    • Lee JW, Fuda H, Javitt NB, Strott CA, Rodriguez IR. Expression and localization of sterol 27-hydroxylase (CYP27A1) in monkey retina. Exp Eye Res 2006;83:465-469
    • (2006) Exp Eye Res , vol.83 , pp. 465-469
    • Lee, J.W.1    Fuda, H.2    Javitt, N.B.3    Strott, C.A.4    Rodriguez, I.R.5
  • 54
    • 77956800486 scopus 로고    scopus 로고
    • Cholesterol oxidation in the retina: Implications of 7KCh formation in chronic inflammation and age-related macular degeneration
    • Rodriguez IR, Larrayoz IM. Cholesterol oxidation in the retina: Implications of 7KCh formation in chronic inflammation and age-related macular degeneration. J Lipid Res 2010;51:2847-2862
    • (2010) J Lipid Res , vol.51 , pp. 2847-2862
    • Rodriguez, I.R.1    Larrayoz, I.M.2
  • 55
    • 52949150827 scopus 로고    scopus 로고
    • Side effects of oxysterols: Cytotoxicity, oxidation, inflammation, and phospholipidosis
    • Vejux A, Malvitte L, Lizard G. Side effects of oxysterols: Cytotoxicity, oxidation, inflammation, and phospholipidosis. Braz J Med Biol Res 2008;41:545-556
    • (2008) Braz J Med Biol Res , vol.41 , pp. 545-556
    • Vejux, A.1    Malvitte, L.2    Lizard, G.3
  • 58
    • 0030876029 scopus 로고    scopus 로고
    • Gender, oestrogen, hormone replacement and age-related macular degeneration: Results from the Blue Mountains Eye Study
    • Smith W, Mitchell P, Wang JJ. Gender, oestrogen, hormone replacement and age-related macular degeneration: Results from the Blue Mountains Eye Study. Aust N Z J Ophthalmol 1997;25:S13-S15
    • (1997) Aust N Z J Ophthalmol , vol.25
    • Smith, W.1    Mitchell, P.2    Wang, J.J.3
  • 59
    • 0028662049 scopus 로고
    • Are sex hormones associated with age-related maculopathy in women? The Beaver Dam Eye Study
    • Klein BE, Klein R, Jensen SC, Ritter LL. Are sex hormones associated with age-related maculopathy in women? The Beaver Dam Eye Study. Trans Am Ophthalmol Soc 1994;92: 289-295
    • (1994) Trans Am Ophthalmol Soc , vol.92 , pp. 289-295
    • Klein, B.E.1    Klein, R.2    Jensen, S.C.3    Ritter, L.L.4
  • 61
    • 20044382242 scopus 로고    scopus 로고
    • Estrogen and brain inflammation: Effects on microglial expression of MHC, costimulatory molecules and cytokines
    • Dimayuga FO, Reed JL, Carnero GA, Wang C, Dimayuga ER, Dimayuga VM, et al. Estrogen and brain inflammation: Effects on microglial expression of MHC, costimulatory molecules and cytokines. J Neuroimmunol 2005;161: 123-136
    • (2005) J Neuroimmunol , vol.161 , pp. 123-136
    • Dimayuga, F.O.1    Reed, J.L.2    Carnero, G.A.3    Wang, C.4    Dimayuga, E.R.5    Dimayuga, V.M.6
  • 62
    • 0033529941 scopus 로고    scopus 로고
    • The antioxidant neuroprotective effects of estrogens and phenolic compounds are independent from their estrogenic properties
    • Moosmann B, Behl C. The antioxidant neuroprotective effects of estrogens and phenolic compounds are independent from their estrogenic properties. Proc Natl Acad Sci U S A 1999;96:8867-8872
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 8867-8872
    • Moosmann, B.1    Behl, C.2
  • 64
    • 0032575752 scopus 로고    scopus 로고
    • Mitochondria and apoptosis
    • Green DR, Reed JC. Mitochondria and apoptosis. Science 1998;281:1309-1312
    • (1998) Science , vol.281 , pp. 1309-1312
    • Green, D.R.1    Reed, J.C.2
  • 65
  • 66
    • 0042266785 scopus 로고    scopus 로고
    • Modulation of antioxidant enzyme expression and function by estrogen
    • Strehlow K, Rotter S, Wassmann S, Adam O, Grohe C, Laufs K, et al. Modulation of antioxidant enzyme expression and function by estrogen. Circ Res 2003;93:170-177
    • (2003) Circ Res , vol.93 , pp. 170-177
    • Strehlow, K.1    Rotter, S.2    Wassmann, S.3    Adam, O.4    Grohe, C.5    Laufs, K.6
  • 67
    • 3042843668 scopus 로고    scopus 로고
    • Estradiol abrogates apoptosis in breast cancer cells through inactivation of bad: Ras-dependent nongenomic pathways requiring signaling through erk and akt
    • Fernando RI, Wimalasena J. Estradiol abrogates apoptosis in breast cancer cells through inactivation of BAD: Ras-dependent nongenomic pathways requiring signaling through ERK and Akt. Mol Biol Cell 2004;15:3266-3284
    • (2004) Mol Biol Cell , vol.15 , pp. 3266-3284
    • Fernando, R.I.1    Wimalasena, J.2
  • 68
    • 39749089950 scopus 로고    scopus 로고
    • 17b-Estradiol abrogates apoptosis in murine skeletal muscle cells through estrogen receptors: Role of the phosphatidylinositol 3-kinase/Akt pathway
    • Vasconsuelo A, Milanesi L, Boland R. 17b-Estradiol abrogates apoptosis in murine skeletal muscle cells through estrogen receptors: Role of the phosphatidylinositol 3-kinase/Akt pathway. J Endocrinol 2008;196:385-397
    • (2008) J Endocrinol , vol.196 , pp. 385-397
    • Vasconsuelo, A.1    Milanesi, L.2    Boland, R.3
  • 69
    • 33744955627 scopus 로고    scopus 로고
    • 17b-estradiol protects against oxidative stress-induced cell death through the glutathione/glutaredoxin-dependent redox regulation of Akt in myocardiac H9c2 Cells
    • Urata Y, Ihara Y, Murata H, Goto S, Koji T, Yodoi J, et al. 17b-estradiol protects against oxidative stress-induced cell death through the glutathione/glutaredoxin-dependent redox regulation of Akt in myocardiac H9c2 Cells. J Biol Chem 2006;281:13092-13102
    • (2006) J Biol Chem , vol.281 , pp. 13092-13102
    • Urata, Y.1    Ihara, Y.2    Murata, H.3    Goto, S.4    Koji, T.5    Yodoi, J.6
  • 71
    • 53149088202 scopus 로고    scopus 로고
    • Role of wild-type estrogen receptorbeta in mitochondrial cytoprotection of cultured normal male and female human lens epithelial cells
    • Flynn JM, Dimitrijevich SD, Younes M, Skliris G, Murphy LC, Cammarata PR. Role of wild-type estrogen receptorbeta in mitochondrial cytoprotection of cultured normal male and female human lens epithelial cells. Am J Physiol Endocrinol Metab 2008;295:E637-E647
    • (2008) Am J Physiol Endocrinol Metab , vol.295
    • Flynn, J.M.1    Dimitrijevich, S.D.2    Younes, M.3    Skliris, G.4    Murphy, L.C.5    Cammarata, P.R.6
  • 73
    • 34447342587 scopus 로고    scopus 로고
    • Interleukin-6 receptor-mediated activation of signal transducer and activator of transcription-3(STAT3) promotes choroidal neovascularization
    • Izumi-Nagai K, Nagai N, Ozawa Y, Mihara M, Ohsugi Y, Kurihara T, et al. Interleukin-6 receptor-mediated activation of signal transducer and activator of transcription-3(STAT3) promotes choroidal neovascularization. Am J Pathol 2007;170:2149-2158
    • (2007) Am J Pathol , vol.170 , pp. 2149-2158
    • Izumi-Nagai, K.1    Nagai, N.2    Ozawa, Y.3    Mihara, M.4    Ohsugi, Y.5    Kurihara, T.6
  • 74
    • 84872296508 scopus 로고    scopus 로고
    • 27-Hydroxycholesterol induces production of tumor necrosis factor-alpha from macrophages
    • Kim SM, Jang H, Son Y, Lee SA, Bae SS, Park YC, et al. 27-Hydroxycholesterol induces production of tumor necrosis factor-alpha from macrophages. Biochem Biophys Res Commun 2013;430:454-459
    • (2013) Biochem Biophys Res Commun , vol.430 , pp. 454-459
    • Kim, S.M.1    Jang, H.2    Son, Y.3    Lee, S.A.4    Bae, S.S.5    Park, Y.C.6
  • 75
    • 80054680024 scopus 로고    scopus 로고
    • Silencing GADD153/CHOP gene expression protects against Alzheimer's disease-like pathology induced by 27- hydroxycholesterol in rabbit hippocampus
    • doi: 10.1371/journal.pone.0026420
    • Prasanthi JR, Larson T, Schommer J, Ghribi O. Silencing GADD153/CHOP gene expression protects against Alzheimer's disease-like pathology induced by 27- hydroxycholesterol in rabbit hippocampus. PLoS One 2011;6:e26420. doi: 10.1371/journal.pone.0026420
    • (2011) PLoS One , vol.6
    • Prasanthi, J.R.1    Larson, T.2    Schommer, J.3    Ghribi, O.4
  • 76
    • 15444368857 scopus 로고    scopus 로고
    • Mechanisms of estrogen receptor signaling: Convergence of genomic and nongenomic actions on target genes
    • Bjornstrom L, Sjoberg M. Mechanisms of estrogen receptor signaling: Convergence of genomic and nongenomic actions on target genes. Mol Endocrinol 2005;19:833-842
    • (2005) Mol Endocrinol , vol.19 , pp. 833-842
    • Bjornstrom, L.1    Sjoberg, M.2
  • 77
    • 0034802322 scopus 로고    scopus 로고
    • Invited review: Cell localization, physiology, and nongenomic actions of estrogen receptors
    • Levin ER. Invited review: Cell localization, physiology, and nongenomic actions of estrogen receptors. J Appl Physiol 2001;91:1860-1867
    • (2001) J Appl Physiol , vol.91 , pp. 1860-1867
    • Levin, E.R.1
  • 78
    • 0029669930 scopus 로고    scopus 로고
    • Tyrosine kinase/p21ras/MAP-kinase pathway activation by estradiol-receptor complex in MCF-7 cells
    • Migliaccio A, Di DM, Castoria G, de FA, Bontempo P, Nola E, et al. Tyrosine kinase/p21ras/MAP-kinase pathway activation by estradiol-receptor complex in MCF-7 cells. EMBO J 1996;15:1292-1300
    • (1996) EMBO J , vol.15 , pp. 1292-1300
    • Migliaccio, A.1    Di, D.M.2    Castoria, G.3    De, F.A.4    Bontempo, P.5    Nola, E.6
  • 79
    • 0034727094 scopus 로고    scopus 로고
    • Interaction of oestrogen receptor with the regulatory subunit of phosphatidylinositol-3-OH kinase
    • Simoncini T, Hafezi-Moghadam A, Brazil DP, Ley K, Chin WW, Liao JK. Interaction of oestrogen receptor with the regulatory subunit of phosphatidylinositol-3-OH kinase. Nature 2000;407:538-541
    • (2000) Nature , vol.407 , pp. 538-541
    • Simoncini, T.1    Hafezi-Moghadam, A.2    Brazil, D.P.3    Ley, K.4    Chin, W.W.5    Liao, J.K.6
  • 80
    • 17944375553 scopus 로고    scopus 로고
    • PI3-kinase in concert with Src promotes the S-phase entry of oestradiol-stimulated MCF-7 cells
    • Castoria G, Migliaccio A, Bilancio A, Di Domenico M, de Falco A, Lombardi M, et al. PI3-kinase in concert with Src promotes the S-phase entry of oestradiol-stimulated MCF-7 cells. EMBO J 2001;20:6050-6059
    • (2001) EMBO J , vol.20 , pp. 6050-6059
    • Castoria, G.1    Migliaccio, A.2    Bilancio, A.3    Di Domenico, M.4    De Falco, A.5    Lombardi, M.6
  • 82
    • 84872317649 scopus 로고    scopus 로고
    • Effects of estrogen on collagen gel contraction by human retinal glial cells
    • Qiu QH, Chen ZY, Yin LL, Zheng Z, Wu XW. Effects of estrogen on collagen gel contraction by human retinal glial cells. Chin Med J (Engl) 2012;125:4098-4103
    • (2012) Chin Med J (Engl , vol.125 , pp. 4098-4103
    • Qiu, Q.H.1    Chen, Z.Y.2    Yin, L.L.3    Zheng, Z.4    Wu, X.W.5


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