Effect of inclusion of lactulose and Lactobacillus plantarum on the intestinal environment and performance of piglets at weaning

Animal Feed Science and Technology

Volumn 185, Issue 3-4, 2013, Pages 160-168

  Guerra Ordaz, A A ^a   Molist, F ^a   Hermes, R G ^a   Gomez de Segura A ^a   La Ragione, R M ^b,c   Woodward, M J ^b,d   Tchorzewska, M A ^b   Collins, J W ^b,e   Perez J F ^a   Martin Orue S M ^a  

^a UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^b VETERINARY LABORATORIES AGENCY   (United Kingdom)

^c UNIVERSITY OF SURREY   (United Kingdom)

^d UNIVERSITY OF READING   (United Kingdom)

^e IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

Lactobacillus plantarum; Lactulose; Piglets; Synbiotic; Weaning

Indexed keywords

BIFIDOBACTERIUM; BIFIDOBACTERIUM THERMACIDOPHILUM; ENTEROBACTERIACEAE; LACTOBACILLUS; LACTOBACILLUS PLANTARUM; SUIDAE;

EID: 84884981726     PISSN: 03778401     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.anifeedsci.2013.07.009     Document Type: Article

References (36)

1. AOAC Official Methods of Analysis 1995, Assoc. Off. Anal. Chem, Washington, DC.
2. Bauer E., Williams B.A., Smidt H., Mosenthin R., Verstegen M.W.A. Influence of dietary components on development of the microbiota in single-stomached species. Nutr. Res. Rev. 2006, 19:63-78.
3. Branner G.R., Bohmer B.M., Erhardt W., Henke J., Roth-Maier D.A. Investigation on the precaecal and faecal digestibility of lactulose and inulin and their influence on nutrient digestibility and microbial characteristics. Arch. Anim. Nutr. 2004, 58:353-366.
4. Bujalance C., Jiménez-Valera M., Moreno E., Ruiz-Bravo A. A selective differential medium for Lactobacillus plantarum. J. Microbiol. Methods. 2006, 66:572-575.
5. Castillo M., Martín-Orúe S.M., Manzanilla E.G., Badiola I., Martín M., Gasa J. Quantification of total bacteria, enterobacteria and lactobacilli populations in pig digesta by real-time PCR. Vet. Microbiol. 2006, 114:165-170.
6. Castillo M., Skene G., Roca M., Anguita M., Badiola I., Duncan S.H., Flint H.J., Martin-Orue S.M. Application of 16S rRNA gene-targeted fluorescence in situ hybridization and restriction fragment length polymorphism to study porcine microbiota along the gastrointestinal tract in response to different sources of dietary fibre. FEMS Microbiol. Ecol. 2007, 59:138-146.
7. Collins J.W., Coldham N.G., Salguero F.J., Cooley W.A., Newell W.R., Rastall R.A., Gibson G.R., Woodward M.J., La Ragione R.M. Response of porcine intestinal in vitro organ culture tissues following exposure to Lactobacillus plantarum JC1 and Salmonella enterica serovar Typhimurium SL1344. Appl. Environ. Microbiol. 2010, 76:6645-6657.
8. Corcoran B.M., Stanton C., Fitzerald G., Ross R.P. Life under stress: the probiotic stress response and how it may be manipulated. Curr. Pharmac. Des. 2008, 14:1382-1399.
9. De Angelis M., Siragusa S., Caputo L., Ragni A., Burzigotti R., Gobbetti M. Survival and persistence of Lactobacillus plantarum 4.1 and Lactobacillus reuteri 3S7 in the gastrointestinal tract of pigs. Vet. Microbiol. 2007, 123:133-144.
10. De Blas C., Mateos G.G., Rebollar P.G. Tables of Composition and Nutritive Value of Raw Materials Used in Compound Feeds 2010, Fundación Española para el Desarrollo de la Nutrición Animal (FEDNA), Madrid, Spain. third ed.
11. Gaggìa F., Mattarelli P., Biavati B. Probiotics and prebiotics in animal feeding for safe food production. Int. J. Food Microbiol. 2010, 141(Suppl. 1):S15-S28.
12. Jensen M.T., Cox R.P., Jensen B.B. Microbial-production of skatole in the hind gut of pigs given different diets and its relation to skatole deposition in backfat. Anim. Sci. 1995, 61:293-304.
13. Kamphues J., Tabeling R., Stuke O., Bollmann S., Amtsberg G. Investigations on potential dietetic effects of lactulose in pigs. Livest. Sci. 2007, 109:93-95.
14. Kennedy J.M., Baldwin B.A. Taste preferences in pigs for nutritive and non-nutritive sweet solutions. Anim. Behav. 1972, 20:706-718.
15. Kitts C.L. Terminal restriction fragment patterns: a tool for comparing microbial communities and assessing community dynamics. Curr. Issues Intestinal Microbiol. 2001, 2:17-25.
16. Kolida S., Gibson G.R. Synbiotics in health and disease. Annu. Rev. Food Sci. Technol. 2011, 2:373-393.
17. Konstantinov S.R., Awati A., Smidt H., Williams B.A., Akkermans A.D.L., de Vos W.M. Specific response of a novel and abundant Lactobacillus amylovorus-Like phylotype to dietary prebiotics in the guts of weaning piglets. Appl. Environ. Microbiol. 2004, 70:3821-3830.
18. Krueger M., Schroedl W., Isik W., Lange W., Hagemann L. Effects of lactulose on the intestinal microflora of periparturient sows and their piglets. Eur. J. Nutr. 2002, 41:26-31.
19. Leser T.D., Amenuvor J.Z., Jensen T.K., Lindecrona R.H., Boye M., Mooller K. Culture-independent analysis of gut bacteria: the pig gastrointestinal tract microbiota revisited. Appl. Environ. Microbiol. 2002, 68:673-690.
20. Li F., Hullar M.A.J., Lampe J.W. Optimization of terminal restriction fragment polymorphism (TRFLP) analysis of human gut microbiota. J. Microbiol. Methods 2007, 68:303-311.
21. Martín-Peláez S., Gibson G.R., Martin-Orue S.M., Klinder A., Rastall R.A., La Ragione R.M., Woodward M.J., Costabile A. In vitro fermentation of carbohydrates by porcine faecal inocula and their influence on Salmonella Typhimurium growth in batch culture systems. FEMS Microbiol. Ecol. 2008, 66:608-619.
22. Martín-Peláez S., Costabile A., Hoyles L., Rastall R.A., Gibson G.R., La Ragione R.M., Woodward M.J., Mateu E., Martín-Orúe S.M. Evaluation of the inclusion of a mixture of organic acids or lactulose into the feed of pigs experimentally challenged with Salmonella Typhimurium. Vet. Microbiol. 2010, 142:337-345.
23. Nemcova R., Bomba A., Gancarcikova S., Reiffova K., Guba P., Koscova J., Jonecova Z., Scirankova L., Bugarsky A. Effects of the administration of lactobacilli, maltodextrins and fructooligosaccharides upon the adhesion of E. coli O8:K88 to the intestinal mucosa and organic acid levels in the gut contents of piglets. Vet. Res. Commun. 2007, 31:791-800.
24. Panesar P.S., Kumari S. Lactulose: production, purification and potential applications. Biotechnol. Adv. 2011, 29:940-948.
25. Pieper R., Janczyk P., Urubschurov V., Korn U., Pieper B., Souffrant W.B. Effect of a single oral administration of Lactobacillus plantarum DSMZ 8862/8866 before and at the time point of weaning on intestinal microbial communities in piglets. Int. J. Food Microbiol. 2009, 130:227-232.
26. Pluske J.R., Hampson D.J., Williams I.H. Factors influencing the structure and function of the small intestine in the weaned pig: a review. Livest. Prod. Sci. 1997, 51:215-236.
27. Richardson A.J., Calder A.G., Stewart C.S., Smith A. Simultaneous determination of volatile and non-volatile acidic fermentation products of anaerobes by capillary gas chromatography. Lett. Appl. Microbiol. 1989, 9:5-8.
28. Saco Y., Fraile L., Giménez M., Alegre A., López-Jimenez R., Cortey M., Segalés J., Bassols A. Serum acute phase proteins as biomarkers of pleuritis and cranio-ventral pulmonary consolidation in slaughter-aged pigs. Res. Vet. Sci. 2011, 91:52-57.
29. Takahashi S., Yoshida Y., Nakanishi N., Tsukahara T., Ushida K. Quantitative real-time PCR monitoring of Escherichia coli and Clostridium perfringens with oral administration of Lactobacillus plantarum strain Lq80 to weaning piglets. Anim. Sci. J. 2008, 79:737-744.
30. The Council of the European Communities, 1986. Council Directive 86/609/EEC of 24 November 1986 on the approximation of laws, regulations and administrative provisions of the Member States regarding the protection of Animals used for Experimental and Scientific purposes. (accessed 4 April 2010). http://ec.europa.eu/food/fs/aw/aw_legislation/scientific/86-609-eec_en.pdf.
31. Thomas L. Urea and blood urea nitrogen (BUN). Clinical Laboratory Diagnostics: Use and Assessment of Clinical Laboratory Results 1998, 374-377. TH-Books Verlagsgesellschaft mbH, Frankfurt/Main, Germany. L. Thomas (Ed.).
32. Van Reenen C.A., Dicks L.M.T. Evaluation of numerical analysis of random amplified polymorphic DNA (RAPD)-PCR as a method to differentiate Lactobacillus plantarum and Lactobacillus pentosus. Curr. Microbiol. 1996, 32:183-187.
33. Van Soest P.J., Robertson J.B., Lewis B.A. Methods for dietary fiber, neutral detergent fiber, and nonstarch polysaccharides in relation to animal nutrition. J. Dairy Sci. 1991, 74:3583-3597.
34. Weber F.L. Effects of lactulose on nitrogen metabolism. Scand. J. Gastroenterol. 1997, 32:83-87.
35. Williams I.H. Growth of the weaned pig. Weaning the Pig: Concepts and Consequences 2003, 17-36. Wageningen Academic Publishers, Wageningen, Netherlands. J.R. Pluske, J.V. Le Dividich, M.W.A. Verstegen (Eds.).
36. Zimmermann B., Bauer E., Mosenthin R. Pro- and prebiotics in pig nutrition -potential modulators of gut health?. J. Anim. Feed Sci. 2001, 10:47-56.