메뉴 건너뛰기




Volumn 305, Issue 7, 2013, Pages

Fulvene-5 inhibition of Nadph oxidases attenuates activation of epithelial sodium channels in A6 distal nephron cells

Author keywords

(H2)DCF DA; Aldosterone; Cell attached patch clamp; Kidney slices; Oxidative stress

Indexed keywords

ANTIHYPERTENSIVE AGENT; EPITHELIAL SODIUM CHANNEL; FULVENE 5; ISOPROTEIN; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SODIUM ION; UNCLASSIFIED DRUG;

EID: 84884961612     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00098.2013     Document Type: Article
Times cited : (13)

References (83)
  • 1
    • 1642308699 scopus 로고    scopus 로고
    • Oxidative stress in hypertension and chronic kidney disease: Role of angiotensin II
    • Agarwal R, Campbell RC, Warnock DG. Oxidative stress in hypertension and chronic kidney disease: role of angiotensin II. Semin Nephrol 24: 101-114, 2004.
    • (2004) Semin Nephrol , vol.24 , pp. 101-114
    • Agarwal, R.1    Campbell, R.C.2    Warnock, D.G.3
  • 2
    • 79960792993 scopus 로고    scopus 로고
    • Pathophysiological roles of NADPH oxidase/nox family proteins in the vascular system
    • Ago T, Kuroda J, Kamouchi M, Sadoshima J, Kitazono T. Pathophysiological roles of NADPH oxidase/nox family proteins in the vascular system. Circ J 75: 1791-1800, 2011.
    • (2011) Circ J , vol.75 , pp. 1791-1800
    • Ago, T.1    Kuroda, J.2    Kamouchi, M.3    Sadoshima, J.4    Kitazono, T.5
  • 3
    • 0028821016 scopus 로고
    • Theodore Cooper Memorial Lecture. Hypertension and the pathogenesis of atherosclerosis Oxidative stress and the mediation of arterial inflammatory response: A new perspective
    • Alexander RW. Theodore Cooper Memorial Lecture. Hypertension and the pathogenesis of atherosclerosis Oxidative stress and the mediation of arterial inflammatory response: a new perspective. Hypertension 25: 155-161, 1995.
    • (1995) Hypertension , vol.25 , pp. 155-161
    • Alexander, R.W.1
  • 4
    • 0033105874 scopus 로고    scopus 로고
    • NADPH oxidase: An update
    • Babior BM. NADPH oxidase: an update. Blood 93: 1464-1476, 1999.
    • (1999) Blood , vol.93 , pp. 1464-1476
    • Babior, B.M.1
  • 5
    • 33846794822 scopus 로고    scopus 로고
    • The NOX family of ROS-generating NADPH oxidases: Physiology and pathophysiology
    • Bedard K, Krause KH. The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology. Physiol Rev 87: 245-313, 2007.
    • (2007) Physiol Rev , vol.87 , pp. 245-313
    • Bedard, K.1    Krause, K.H.2
  • 7
    • 70149091965 scopus 로고    scopus 로고
    • Subcellular localization of Nox4 and regulation in diabetes
    • Block K, Gorin Y, Abboud HE. Subcellular localization of Nox4 and regulation in diabetes. Proc Natl Acad Sci USA 106: 14385-14390, 2009.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 14385-14390
    • Block, K.1    Gorin, Y.2    Abboud, H.E.3
  • 9
    • 46749135175 scopus 로고    scopus 로고
    • DCFH2 interactions with hydroxyl radicals and other oxidants-influence of organic solvents
    • Bromme HJ, Zuhlke L, Silber RE, Simm A. DCFH2 interactions with hydroxyl radicals and other oxidants-influence of organic solvents. Exp Gerontol 43: 638-644, 2008.
    • (2008) Exp Gerontol , vol.43 , pp. 638-644
    • Bromme, H.J.1    Zuhlke, L.2    Silber, R.E.3    Simm, A.4
  • 12
    • 4344688048 scopus 로고    scopus 로고
    • An improved pathway to 6,6-disubstituted fulvenes
    • Chajara K, Ottosson H. An improved pathway to 6,6-disubstituted fulvenes. Tetrahedron Lett 45: 6741-6744, 2004.
    • (2004) Tetrahedron Lett , vol.45 , pp. 6741-6744
    • Chajara, K.1    Ottosson, H.2
  • 13
    • 3042527868 scopus 로고    scopus 로고
    • The NADPH oxidase of professional phagocytesprototype of the NOX electron transport chain systems
    • Cross AR, Segal AW. The NADPH oxidase of professional phagocytesprototype of the NOX electron transport chain systems. Biochim Biophys Acta 1657: 1-22, 2004.
    • (2004) Biochim Biophys Acta , vol.1657 , pp. 1-22
    • Cross, A.R.1    Segal, A.W.2
  • 14
    • 27644456575 scopus 로고    scopus 로고
    • NAD(P)H oxidase 4 mediates transforming growth factorbeta1-induced differentiation of cardiac fibroblasts into myofibroblasts
    • Cucoranu I, Clempus R, Dikalova A, Phelan PJ, Ariyan S, Dikalov S, Sorescu D. NAD(P)H oxidase 4 mediates transforming growth factorbeta1-induced differentiation of cardiac fibroblasts into myofibroblasts. Circ Res 97: 900-907, 2005.
    • (2005) Circ Res , vol.97 , pp. 900-907
    • Cucoranu, I.1    Clempus, R.2    Dikalova, A.3    Phelan, P.J.4    Ariyan, S.5    Dikalov, S.6    Sorescu, D.7
  • 15
    • 33744791069 scopus 로고    scopus 로고
    • New York: Lange Medical Books/McGraw Hill, Medical Pub. Division
    • Eaton DCP, Vander AJ. Vander's Renal Physiology. New York: Lange Medical Books/McGraw Hill, Medical Pub. Division, 2004.
    • (2004) Vander's Renal Physiology
    • Eaton, D.C.P.1    Vander, A.J.2
  • 18
    • 0036796875 scopus 로고    scopus 로고
    • Oxidative stress and stress-activated signaling pathways: A unifying hypothesis of type 2 diabetes
    • Evans JL, Goldfine ID, Maddux BA, Grodsky GM. Oxidative stress and stress-activated signaling pathways: a unifying hypothesis of type 2 diabetes. Endocr Rev 23: 599-622, 2002.
    • (2002) Endocr Rev , vol.23 , pp. 599-622
    • Evans, J.L.1    Goldfine, I.D.2    Maddux, B.A.3    Grodsky, G.M.4
  • 19
    • 4544363652 scopus 로고    scopus 로고
    • Detection of intracellular superoxide formation in endothelial cells and intact tissues using dihydroethidium and an HPLC-based assay
    • Fink B, Laude K, McCann L, Doughan A, Harrison DG, Dikalov S. Detection of intracellular superoxide formation in endothelial cells and intact tissues using dihydroethidium and an HPLC-based assay. Am J Physiol Cell Physiol 287: C895-C902, 2004.
    • (2004) Am J Physiol Cell Physiol , vol.287
    • Fink, B.1    Laude, K.2    McCann, L.3    Doughan, A.4    Harrison, D.G.5    Dikalov, S.6
  • 20
    • 0032704101 scopus 로고    scopus 로고
    • Antioxidants, oxidative stress, and degenerative neurological disorders
    • Floyd RA. Antioxidants, oxidative stress, and degenerative neurological disorders. Proc Soc Exp Biol Med 222: 236-245, 1999.
    • (1999) Proc Soc Exp Biol Med , vol.222 , pp. 236-245
    • Floyd, R.A.1
  • 21
    • 48249085391 scopus 로고    scopus 로고
    • Oxidative stress as a major culprit in kidney disease in diabetes
    • Forbes JM, Coughlan MT, Cooper ME. Oxidative stress as a major culprit in kidney disease in diabetes. Diabetes 57: 1446-1454, 2008.
    • (2008) Diabetes , vol.57 , pp. 1446-1454
    • Forbes, J.M.1    Coughlan, M.T.2    Cooper, M.E.3
  • 23
    • 10644262971 scopus 로고    scopus 로고
    • The Nox family of NAD(P)H oxidases: Host defense and beyond
    • Geiszt M, Leto TL. The Nox family of NAD(P)H oxidases: host defense and beyond. J Biol Chem 279: 51715-51718, 2004.
    • (2004) J Biol Chem , vol.279 , pp. 51715-51718
    • Geiszt, M.1    Leto, T.L.2
  • 27
    • 0242349764 scopus 로고    scopus 로고
    • Oxidative stress and cardiovascular injury: Part II: Animal and human studies
    • Griendling KK, FitzGerald GA. Oxidative stress and cardiovascular injury: Part II: animal and human studies. Circulation 108: 2034-2040, 2003.
    • (2003) Circulation , vol.108 , pp. 2034-2040
    • Griendling, K.K.1    FitzGerald, G.A.2
  • 28
    • 0842289901 scopus 로고    scopus 로고
    • Assessment of renal functional phenotype in mice lacking gp91PHOX subunit of NAD(P)H oxidase
    • Haque MZ, Majid DS. Assessment of renal functional phenotype in mice lacking gp91PHOX subunit of NAD(P)H oxidase. Hypertension 43: 335-340, 2004.
    • (2004) Hypertension , vol.43 , pp. 335-340
    • Haque, M.Z.1    Majid, D.S.2
  • 30
    • 46449129179 scopus 로고    scopus 로고
    • Nox4 oxidase overexpression specifically decreases endogenous Nox4 mRNA and inhibits angiotensin II-induced adventitial myofibroblast migration
    • Haurani MJ, Cifuentes ME, Shepard AD, Pagano PJ. Nox4 oxidase overexpression specifically decreases endogenous Nox4 mRNA and inhibits angiotensin II-induced adventitial myofibroblast migration. Hypertension 52: 143-149, 2008.
    • (2008) Hypertension , vol.52 , pp. 143-149
    • Haurani, M.J.1    Cifuentes, M.E.2    Shepard, A.D.3    Pagano, P.J.4
  • 31
    • 53049084826 scopus 로고    scopus 로고
    • Redox regulation of epithelial sodium channels examined in alveolar type 1 and 2 cells patch-clamped in lung slice tissue
    • Helms MN, Jain L, Self JL, Eaton DC. Redox regulation of epithelial sodium channels examined in alveolar type 1 and 2 cells patch-clamped in lung slice tissue. J Biol Chem 283: 22875-22883, 2008.
    • (2008) J Biol Chem , vol.283 , pp. 22875-22883
    • Helms, M.N.1    Jain, L.2    Self, J.L.3    Eaton, D.C.4
  • 37
    • 0031857290 scopus 로고    scopus 로고
    • Interaction of reactive oxygen species with ion transport mechanisms
    • Kourie JI. Interaction of reactive oxygen species with ion transport mechanisms. Am J Physiol Cell Physiol 275: C1-C24, 1998.
    • (1998) Am J Physiol Cell Physiol , vol.275
    • Kourie, J.I.1
  • 39
  • 42
    • 0032545445 scopus 로고    scopus 로고
    • Diphenyleneiodonium, an NAD(P)H oxidase inhibitor, also potently inhibits mitochondrial reactive oxygen species production
    • Li Y, Trush MA. Diphenyleneiodonium, an NAD(P)H oxidase inhibitor, also potently inhibits mitochondrial reactive oxygen species production. Biochem Biophys Res Commun 253: 295-299, 1998.
    • (1998) Biochem Biophys Res Commun , vol.253 , pp. 295-299
    • Li, Y.1    Trush, M.A.2
  • 44
    • 80052780146 scopus 로고    scopus 로고
    • Hydrogen peroxide stimulates the epithelial sodium channel through a phosphatidylinositide 3-kinase-dependent pathway
    • Ma HP. Hydrogen peroxide stimulates the epithelial sodium channel through a phosphatidylinositide 3-kinase-dependent pathway. J Biol Chem 286: 32444-32453, 2011.
    • (2011) J Biol Chem , vol.286 , pp. 32444-32453
    • Ma, H.P.1
  • 45
    • 0036080649 scopus 로고    scopus 로고
    • ATP masks stretch activation of epithelial sodium channels in A6 distal nephron cells
    • Ma HP, Li L, Zhou ZH, Eaton DC, Warnock DG. ATP masks stretch activation of epithelial sodium channels in A6 distal nephron cells. Am J Physiol Renal Physiol 282: F501-F505, 2002.
    • (2002) Am J Physiol Renal Physiol , vol.282
    • Ma, H.P.1    Li, L.2    Zhou, Z.H.3    Eaton, D.C.4    Warnock, D.G.5
  • 47
    • 26244444476 scopus 로고    scopus 로고
    • Functional analysis of Nox4 reveals unique characteristics compared to other NADPH oxidases
    • Martyn KD, Frederick LM, von Loehneysen K, Dinauer MC, Knaus UG. Functional analysis of Nox4 reveals unique characteristics compared to other NADPH oxidases. Cell Signal 18: 69-82, 2006.
    • (2006) Cell Signal , vol.18 , pp. 69-82
    • Martyn, K.D.1    Frederick, L.M.2    von Loehneysen, K.3    Dinauer, M.C.4    Knaus, U.G.5
  • 48
    • 54149115156 scopus 로고    scopus 로고
    • Insulin-like growth factor-I induces reactive oxygen species production and cell migration through Nox4 and Rac1 in vascular smooth muscle cells
    • Meng D, Lv DD, Fang J. Insulin-like growth factor-I induces reactive oxygen species production and cell migration through Nox4 and Rac1 in vascular smooth muscle cells. Cardiovasc Res 80: 299-308, 2008.
    • (2008) Cardiovasc Res , vol.80 , pp. 299-308
    • Meng, D.1    Lv, D.D.2    Fang, J.3
  • 50
    • 33750303961 scopus 로고    scopus 로고
    • Phagocytosis-coupled activation of the superoxide-producing phagocyte oxidase, a member of the NADPH oxidase (Nox) family
    • Minakami R, Sumimoto H. Phagocytosis-coupled activation of the superoxide-producing phagocyte oxidase, a member of the NADPH oxidase (Nox) family. Int J Hematol 84: 193-198, 2006.
    • (2006) Int J Hematol , vol.84 , pp. 193-198
    • Minakami, R.1    Sumimoto, H.2
  • 53
    • 84862525472 scopus 로고    scopus 로고
    • Oxidative stress, Noxs, and hypertension: Experimental evidence and clinical controversies
    • Montezano AC, Touyz RM. Oxidative stress, Noxs, and hypertension: experimental evidence and clinical controversies. Annal Med 44, Suppl 1: S2-S16, 2012.
    • (2012) Annal Med , vol.44 , Issue.SUPPL. 1
    • Montezano, A.C.1    Touyz, R.M.2
  • 54
    • 58249093939 scopus 로고    scopus 로고
    • How mitochondria produce reactive oxygen species
    • Murphy MP. How mitochondria produce reactive oxygen species. Biochem J 417: 1-13, 2009.
    • (2009) Biochem J , vol.417 , pp. 1-13
    • Murphy, M.P.1
  • 55
    • 1342322653 scopus 로고    scopus 로고
    • Increased prevalence of oxidant stress and inflammation in patients with moderate to severe chronic kidney disease
    • Oberg BP, McMenamin E, Lucas FL, McMonagle E, Morrow J, Ikizler TA, Himmelfarb J. Increased prevalence of oxidant stress and inflammation in patients with moderate to severe chronic kidney disease. Kidney Int 65: 1009-1016, 2004.
    • (2004) Kidney Int , vol.65 , pp. 1009-1016
    • Oberg, B.P.1    McMenamin, E.2    Lucas, F.L.3    McMonagle, E.4    Morrow, J.5    Ikizler, T.A.6    Himmelfarb, J.7
  • 56
    • 0037428064 scopus 로고    scopus 로고
    • Stretch enhances contraction of bovine coronary arteries via an NAD(P)H oxidase-mediated activation of the extracellular signal-regulated kinase mitogen-activated protein kinase cascade
    • Oeckler RA, Kaminski PM, Wolin MS. Stretch enhances contraction of bovine coronary arteries via an NAD(P)H oxidase-mediated activation of the extracellular signal-regulated kinase mitogen-activated protein kinase cascade. Circ Res 92: 23-31, 2003.
    • (2003) Circ Res , vol.92 , pp. 23-31
    • Oeckler, R.A.1    Kaminski, P.M.2    Wolin, M.S.3
  • 58
    • 4744373355 scopus 로고    scopus 로고
    • Localization of Nox2 N-terminus using polyclonal antipeptide antibodies
    • Paclet MH, Henderson LM, Campion Y, Morel F, Dagher MC. Localization of Nox2 N-terminus using polyclonal antipeptide antibodies. Biochem J 382: 981-986, 2004.
    • (2004) Biochem J , vol.382 , pp. 981-986
    • Paclet, M.H.1    Henderson, L.M.2    Campion, Y.3    Morel, F.4    Dagher, M.C.5
  • 59
    • 41149150716 scopus 로고    scopus 로고
    • NADPH oxidases, reactive oxygen species, and hypertension: Clinical implications and therapeutic possibilities
    • Paravicini TM, Touyz RM. NADPH oxidases, reactive oxygen species, and hypertension: clinical implications and therapeutic possibilities. Diabetes Care 31, Suppl 2: S170-S180, 2008.
    • (2008) Diabetes Care , vol.31 , Issue.SUPPL. 2
    • Paravicini, T.M.1    Touyz, R.M.2
  • 60
    • 33750519444 scopus 로고    scopus 로고
    • Role of NADPH oxidase 4 in lipopolysaccharide-induced proinflammatory responses by human aortic endothelial cells
    • Park HS, Chun JN, Jung HY, Choi C, Bae YS. Role of NADPH oxidase 4 in lipopolysaccharide-induced proinflammatory responses by human aortic endothelial cells. Cardiovasc Res 72: 447-455, 2006.
    • (2006) Cardiovasc Res , vol.72 , pp. 447-455
    • Park, H.S.1    Chun, J.N.2    Jung, H.Y.3    Choi, C.4    Bae, Y.S.5
  • 63
    • 0037205443 scopus 로고    scopus 로고
    • Diphenyleneiodonium triggers the efflux of glutathione from cultured cells
    • Pullar JM, Hampton MB. Diphenyleneiodonium triggers the efflux of glutathione from cultured cells. J Biol Chem 277: 19402-19407, 2002.
    • (2002) J Biol Chem , vol.277 , pp. 19402-19407
    • Pullar, J.M.1    Hampton, M.B.2
  • 65
    • 9144274479 scopus 로고    scopus 로고
    • Diphenyleneiodonium inhibits the cell redox metabolism and induces oxidative stress
    • Riganti C, Gazzano E, Polimeni M, Costamagna C, Bosia A, Ghigo D. Diphenyleneiodonium inhibits the cell redox metabolism and induces oxidative stress. J Biol Chem 279: 47726-47731, 2004.
    • (2004) J Biol Chem , vol.279 , pp. 47726-47731
    • Riganti, C.1    Gazzano, E.2    Polimeni, M.3    Costamagna, C.4    Bosia, A.5    Ghigo, D.6
  • 66
    • 34447528855 scopus 로고    scopus 로고
    • FcgammaRIIa mediates C-reactive protein-induced inflammatory responses of human vascular smooth muscle cells by activating NADPH oxidase 4
    • Ryu J, Lee CW, Shin JA, Park CS, Kim JJ, Park SJ, Han KH. FcgammaRIIa mediates C-reactive protein-induced inflammatory responses of human vascular smooth muscle cells by activating NADPH oxidase 4. Cardiovasc Res 75: 555-565, 2007.
    • (2007) Cardiovasc Res , vol.75 , pp. 555-565
    • Ryu, J.1    Lee, C.W.2    Shin, J.A.3    Park, C.S.4    Kim, J.J.5    Park, S.J.6    Han, K.H.7
  • 69
    • 84870563253 scopus 로고    scopus 로고
    • channels. Focus on ethanol stimulates epithelial sodium channels by elevating reactive oxygen species
    • channels. Focus on ethanol stimulates epithelial sodium channels by elevating reactive oxygen species. Am J Physiol Cell Physiol 303: C1125-C1126, 2012.
    • (2012) Am J Physiol Cell Physiol , vol.303
    • Snyder, P.M.1
  • 72
    • 84863238020 scopus 로고    scopus 로고
    • Angiotensin II stimulates epithelial sodium channels in the cortical collecting duct of the rat kidney
    • Sun P, Yue P, Wang WH. Angiotensin II stimulates epithelial sodium channels in the cortical collecting duct of the rat kidney. Am J Physiol Renal Physiol 302: F679-F687, 2012.
    • (2012) Am J Physiol Renal Physiol , vol.302
    • Sun, P.1    Yue, P.2    Wang, W.H.3
  • 74
    • 38549156600 scopus 로고    scopus 로고
    • Apocynin, NADPH oxidase, and vascular cells: A complex matter
    • Touyz RM. Apocynin, NADPH oxidase, and vascular cells: a complex matter. Hypertension 51: 172-174, 2008.
    • (2008) Hypertension , vol.51 , pp. 172-174
    • Touyz, R.M.1
  • 75
    • 0142150051 scopus 로고    scopus 로고
    • Mitochondrial formation of reactive oxygen species
    • Turrens JF. Mitochondrial formation of reactive oxygen species. J Physiol 552: 335-344, 2003.
    • (2003) J Physiol , vol.552 , pp. 335-344
    • Turrens, J.F.1
  • 76
    • 65349157681 scopus 로고    scopus 로고
    • Compartmentalization of redox signaling through NADPH oxidase-derived ROS
    • Ushio-Fukai M. Compartmentalization of redox signaling through NADPH oxidase-derived ROS. Antioxid Redox Signal 11: 1289-1299, 2009.
    • (2009) Antioxid Redox Signal , vol.11 , pp. 1289-1299
    • Ushio-Fukai, M.1
  • 77
    • 4043107129 scopus 로고    scopus 로고
    • Roles of oxidative stress and antioxidant therapy in chronic kidney disease and hypertension
    • Vaziri ND. Roles of oxidative stress and antioxidant therapy in chronic kidney disease and hypertension. Curr Opin Nephrol Hypertens 13: 93-99, 2004.
    • (2004) Curr Opin Nephrol Hypertens , vol.13 , pp. 93-99
    • Vaziri, N.D.1
  • 78
    • 0033854560 scopus 로고    scopus 로고
    • Induction of oxidative stress by glutathione depletion causes severe hypertension in normal rats
    • Vaziri ND, Wang XQ, Oveisi F, Rad B. Induction of oxidative stress by glutathione depletion causes severe hypertension in normal rats. Hypertension 36: 142-146, 2000.
    • (2000) Hypertension , vol.36 , pp. 142-146
    • Vaziri, N.D.1    Wang, X.Q.2    Oveisi, F.3    Rad, B.4
  • 79
    • 14544290505 scopus 로고    scopus 로고
    • Apocynin inhibits NADPH oxidase in phagocytes but stimulates ROS production in non-phagocytic cells
    • Vejrazka M, Micek R, Stipek S. Apocynin inhibits NADPH oxidase in phagocytes but stimulates ROS production in non-phagocytic cells. Biochim Biophys Acta 1722: 143-147, 2005.
    • (2005) Biochim Biophys Acta , vol.1722 , pp. 143-147
    • Vejrazka, M.1    Micek, R.2    Stipek, S.3
  • 80
    • 0036710445 scopus 로고    scopus 로고
    • The superoxide-generating NADPH oxidase: Structural aspects and activation mechanism
    • Vignais PV. The superoxide-generating NADPH oxidase: structural aspects and activation mechanism. Cell Mol Life Sci 59: 1428-1459, 2002.
    • (2002) Cell Mol Life Sci , vol.59 , pp. 1428-1459
    • Vignais, P.V.1
  • 82
    • 36049047731 scopus 로고    scopus 로고
    • Aldosterone-induced increases in superoxide production counters nitric oxide inhibition of epithelial Na channel activity in A6 distal nephron cells
    • Yu L, Bao HF, Self JL, Eaton DC, Helms MN. Aldosterone-induced increases in superoxide production counters nitric oxide inhibition of epithelial Na channel activity in A6 distal nephron cells. Am J Physiol Renal Physiol 293: F1666-F1677, 2007.
    • (2007) Am J Physiol Renal Physiol , vol.293
    • Yu, L.1    Bao, H.F.2    Self, J.L.3    Eaton, D.C.4    Helms, M.N.5
  • 83
    • 57349191615 scopus 로고    scopus 로고
    • Single-channel analysis of functional epithelial sodium channel (ENaC) stability at the apical membrane of A6 distal kidney cells
    • Yu L, Helms MN, Yue Q, Eaton DC. Single-channel analysis of functional epithelial sodium channel (ENaC) stability at the apical membrane of A6 distal kidney cells. Am J Physiol Renal Physiol 295: F1519-F1527, 2008.
    • (2008) Am J Physiol Renal Physiol , vol.295
    • Yu, L.1    Helms, M.N.2    Yue, Q.3    Eaton, D.C.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.