Diabetes impairs the interactions between long-term hematopoietic stem cells and osteopontin-positive cells in the endosteal niche of mouse bone marrow

American Journal of Physiology - Cell Physiology

Volumn 305, Issue 7, 2013, Pages

  Chiba, Hironori ^a   Ataka, Koji ^a   Iba, Kousuke ^a   Nagaishi, Kanna ^a   Yamashita, Toshihiko ^a   Fujimiya, Mineko ^a  

^a SAPPORO MEDICAL UNIVERSITY   (Japan)

Author keywords

Intrabone marrow bone marrow transplantation; Osteoblastic niche; Tie2

Indexed keywords

ANGIOPOIETIN 1; ANGIOPOIETIN RECEPTOR; BETA CATENIN; BETA1 INTEGRIN; CHEMOKINE; CHEMOKINE RECEPTOR; MESSENGER RNA; NERVE CELL ADHESION MOLECULE; OSTEOPONTIN; STROMAL CELL DERIVED FACTOR 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL DIVISION; CELL PROLIFERATION; CONTROLLED STUDY; DIABETES MELLITUS; GENE EXPRESSION; HEMATOPOIETIC STEM CELL; IN VITRO STUDY; MALE; MICROENVIRONMENT; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM; STEM CELL MOBILIZATION; STREPTOZOCIN DIABETES;

INTRABONE MARROW-BONE MARROW TRANSPLANTATION; OSTEOBLASTIC NICHE; TIE2;

ANIMALS; BIOLOGICAL MARKERS; BONE MARROW TRANSPLANTATION; CELL COMMUNICATION; CELLS, CULTURED; COCULTURE TECHNIQUES; DIABETES MELLITUS, EXPERIMENTAL; GENE EXPRESSION REGULATION; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HEMATOPOIETIC STEM CELLS; MALE; MICE; MICE, INBRED C57BL; OSTEOBLASTS; OSTEOPONTIN; RNA, MESSENGER; SIGNAL TRANSDUCTION; STEM CELL NICHE; TIME FACTORS;

EID: 84884937317     PISSN: 03636143     EISSN: 15221563     Source Type: Journal    
DOI: 10.1152/ajpcell.00400.2012     Document Type: Article

References (37)

1. Arai F, Suda T. Maintenance of quiescent hematopoietic stem cells in the osteoblastic niche. Ann NY Acad Sci 106: 41-53, 2007.
2. Baron R, Rawadi G. Targeting the Wnt/beta-catenin pathway to regulate bone formation in the adult skeleton. Endocrinology 148: 2635-2643, 2007.
3. Bar-Shavit Z. The osteoclast: a multinucleated, hematopoietic-origin, bone-resorbing osteoimmune cell. J Cell Biochem 102: 1130-1139, 2007.
4. Chan L, Terashima T, Fujimiya M, Kojima H. Chronic diabetic complications: the body's adaptive response to hyperglycemia gone awry? Trans Am Clin Climatol Assoc 117: 341-351, 2006.
5. Ehninger A, Trumpp A. The bone marrow stem cell niche grows up: mesenchymal stem cells and macrophages move in. J Exp Med 208: 421-428, 2011.
6. Fadini GP, Boscaro E, de Kreutzenberg S, Agostini C, Seeger F, Dimmeler S, Zeiher A, Tiengo A, Avogaro A. Time course and mechanisms of circulating progenitor cell reduction in the natural history of type 2 diabetes. Diabetes Care 33: 1097-1102, 2010.
7. Ferraro F, Lymperi S, Méndez-Ferrer S, Saez B, Spencer JA, Yeap BY, Masselli E, Graiani G, Prezioso L, Rizzini EL, Mangoni M, Rizzoli V, Sykes SM, Lin CP, Frenette PS, Quaini F, Scadden DT. Diabetes impairs hematopoietic stem cell mobilization by altering niche function. Sci Transl Med 3: 101-104, 2011.
8. Fleming HE, Janzen V, Lo Celso C, Guo J, Leahy KM, Kronenberg HM, Scadden DT. Wnt signaling in the niche enforces hematopoietic stem cell quiescence and is necessary to preserve self-renewal in vivo. Cell Stem Cell 2: 274-283, 2008.
9. Fujimiya M, Kojima H, Ichinose M, Arai R, Kimura H, Kashiwagi A, Chan L. Fusion of proinsulin-producing bone marrow-derived cells with hepatocytes in diabetes. Proc Natl Acad Sci USA 104: 4030-4035, 2007.
10. Gottschling S, Saffrich R, Seckinger A, Krause U, Horsch K, Miesala K, Ho AD. Human mesenchymal stromal cells regulate initial selfrenewing divisions of hematopoietic progenitor cells by a beta1-integrindependent mechanism. Stem Cells 25: 798-806, 2007.
11. Haug JS, He XC, Grindley JC, Wunderlich JP, Gaudenz K, Ross JT, Paulson A, Wagner KP, Xie Y, Zhu R, Yin T, Perry JM, Hembree MJ, Redenbaugh EP, Radice GL, Seidel C, Li L. N-cadherin expression level distinguished reserved versus primed states of hematopoietic stem cells. Cell Stem Cells 2: 367-379, 2008.
12. Hosokawa K, Arai F, Yoshihara H, Iwasaki H, Nakamura Y, Gomei Y, Suda T. Knockdown of N-cadherin suppresses the long-term engraftment of hematopoietic stem cells. Blood 116: 554-563, 2010.
13. Jing D, Wobus M, Poitz DM, Bornhauser M, Ehninger G, Ordemann R. Oxygen tension plays a critical role in the hematopoieticmicroenvironment in vitro. Hematologica 97: 331-339, 2012.
14. Kawamoto T. Use of a new adhesive film for the preparation of multipurpose fresh-frozen sections from hard tissues, whole-animals, insects and plants. Arch Histol Cytol 66: 123-143, 2003.
15. Kirstetter P, Anderson K, Porse BT, Jacobsen SE, Nerlov C. Activation of the canonical Wnt pathway leads to loss of hematopoietic stem cell repopulation and multilineage differentiation block. Nat Immunol 7: 1048-1056, 2006.
16. Kushida T, Inaba M, Hisha H, Ichioka N, Esumi T, Ogawa R, Iida H, Ikehara S. Intra-bone marrow injection of allogeneic bone marrow cells: a powerful new strategy for treatment of intractable autoimmune diseases in MRL/lpr mice. Blood 97: 3292-3299, 2001.
17. Leisten I, Kramann R, Ventura Ferreira MS, Bovi M, Neuss S, Ziegler P, Wagner W, Knüchel R, Schneider RK. 3D coculture of hematopoietic stem and progenitor cells and mesenchymal stem cells in collagen scaffolds as a model of the hematopoietic niche. Biomaterials 3: 1736 1747, 2012.
18. Li L, Bhatia R. Stem cell quiescence. Clin Cancer Res 17: 4936-4941, 2011.
19. Loomans CJ, de Koning EJ, Staal FJ, Rookmaaker MB, Verseyden C, de Boer HC, Verhaar MC, Braam B, Rabelink TJ, van Zonneveld AJ. Endothelial progenitor cell dysfunction: a novel concept in the pathogenesis of vascular complications of type 1 diabetes. Diabetes 53: 195-199, 2004.
20. Ma Z, Wirström T, Borg LA, Larsson-Nyrén G, Hals I, BondoHansen J, Grill V, Björklund A. Diabetes reduces-cell mitochondria and induces distinct morphological abnormalities, which are reproducible by high glucose in vitro with attendant dysfunction. Islets 4: 233-242, 2012.
21. Mayack SR, Shadrach JL, Kim FS, Wagers AJ. Systemic signals regulate ageing and rejuvenation of blood stem cell niches. Nature 463: 495-500, 2010.
22. Méndez-Ferrer S, Michurina TV, Ferraro F, Mazloom AR, Macarthur BD, Lira SA, Scadden DT, Ma'ayan A, Enikolopov GN, Frenette PS. Mesenchymal and haematopoietic stem cells form a unique bone marrow niche. Nature 466: 829-834, 2010.
23. Mercier FE, Ragu C, Scadden DT. The bone marrow at the crossroads of blood and immunity. Nat Rev Immunol 12: 49-60, 2012.
24. Motyl K, McCabe LR. Streptozotocin, type I diabetes severity and bone Biol Proced Online 11: 296-315, 2009.
25. Ogawa M. Differentiation and proliferation of hematopoietic stem cells. Blood 81: 2844-2853, 1993.
26. Omatsu Y, Sugiyama T, Kohara H, Kondoh G, Fujii N, Kohno K, Nagasawa T. The essential functions of adipo-osteogenic progenitors as the hematopoietic stem and progenitor cell niche. Immunity 33: 387-399, 2010.
27. Orlandi A, Chavakis E, Seeger F, Tjwa M, Zeiher AM, Dimmeler S. Long-term diabetes impairs repopulation of hematopoietic progenitor cells and dysregulates the cytokine expression in the bone marrow microenvironment in mice. Basic Res Cardiol 105: 703-712, 2010.
28. Sharma MB, Limaye LS, Kale VP. Mimicking the functional hematopoietic stem cell niche in vitro: recapitulation of marrow physiology by hydrogel-based three-dimensional cultures of mesenchymal stromal cells. Hematologica 97: 651-660, 2012.
29. Suda T, Arai F. Wnt signaling in the niche. Cell 132: 729-730, 2008.
30. Tepper OM, Carr J, Allen RJ Jr, Chang CC, Lin Tanaka R CD, Gupta SM, Levine JP, Saadeh PB, Warren SM. Decreased circulating progenitor cell number and failed mechanisms of stromal cell-derived factor-1alpha mediated bone marrow mobilization impair diabetic tissue repair. Diabetes 59: 1974-1983, 2010.
31. Terashima T, Kojima H, Fujimiya M, Matsumura K, Oi J, Hara M, Kashiwagi A, Kimura H, Yasuda H, Chan L. The fusion of bonemarrow-derived proinsulin-expressing cells with nerve cells underlies diabetic neuropathy. Proc Natl Acad Sci USA 102: 12525-12530, 2005.
32. Tariq M, Masoud MS, Mehmood A, Khan SN, Riazuddin S. Stromal cell derived factor-1alpha protects stem cell derived insulin-producing cells from glucotoxicity under high glucose conditions in-vitro and ameliorates drug induced diabetes in rats. J Transl Med 11: 115, 2013.
33. Tzeng YS, Li H, Kang YL, Chen WC, Cheng WC, Lai DM. Loss of Cxcl12/Sdf-1 in adult mice decreases the quiescent state of hematopoietic stem/progenitor cells and alters the pattern of hematopoietic regeneration after myelosuppression. Blood 117: 429-439, 2011.
34. Wang DL, Wagers AJ. Dynamic niches in the origination and differentiation of haematopoietic stem cells. Nat Rev Mol Cell Biol 12: 643-655, 2011.
35. Weksberg DC, Chambers SM, Boles NC, Goodell MA. CD150side population cells represent a functionally distinct population of long-term hematopoietic stem cells. Blood 111: 2444-2451, 2008.
36. Yamashita T, Fujimiya M, Nagaishi K, Ataka K, Tanaka M, Yoshida H, Tsuchihashi K, Shimamoto K, Miura T. Fusion of bone marrowderived cells with renal tubules contributes to renal dysfunction in diabetic nephropathy. FASEB J 26: 1559-1568, 2012.
37. Zou YR, Kottmann AH, Kuroda M, Taniuchi I, Littman DR. Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development. Nature 393: 595-599, 1998.