Streptozotocin, type i diabetes severity and bone

Biological Procedures Online

Volumn 11, Issue 1, 2009, Pages 296-315

  Motyl, Katherine ^a   McCabe, Laura R ^a  

^a NONE

Author keywords

Adipocytes; Bone; Diabetes mellitus; Mice; Osteocalcin; Osteoporosis; Streptozotocin; Type I

Indexed keywords

EID: 84355163630     PISSN: None     EISSN: 14809222     Source Type: Journal    
DOI: 10.1007/s12575-009-9000-5     Document Type: Article

References (73)

1. Bouillon, R., et al (1995) Influence of age, sex, and insulin on osteoblast function: osteoblast dysfunction in diabetes mellitus. J Clin Endocrinol Metab 80 (4):1194-202
2. Kemink, S. A., et al (2000) Osteopenia in insulin-dependent diabetes mellitus; prevalence and aspects of pathophysiology. J Endocrinol Invest 23(5):295-303
3. Auwerx, J., et al (1988) Mineral metabolism and bone mass at peripheral and axial skeleton in diabetes mellitus. Diabetes 37(1):8-12
4. Krakauer, J. C., et al (1995) Bone loss and bone turnover in diabetes. Diabetes 44 (7):775-82
5. Levin, M. E., Boisseau, V. C., Avioli, L. V. (1976) Effects of diabetes mellitus on bone mass in juvenile and adult-onset diabetes. N Engl J Med 294(5):241-245
6. Tuominen, J. T., et al (1999) Bone mineral density in patients with type 1 and type 2 diabetes. Diabetes Care 22(7):1196-1200
7. Munoz-Torres, M., et al (1996) Bone mineral density measured by dual X-ray absorptiometry in Spanish patients with insulindependent diabetes mellitus. Calcif Tissue Int 58(5):316-319
8. Buysschaert, M., et al (1992) Proximal femur density in type 1 and 2 diabetic patients. Diabetes Metab 18(1):32-37
9. Hadjidakis, D. J., et al (2006) Bone mineral density of both genders in type 1 diabetes according to bone composition. J Diabetes Its Complicat 20(5):302-307
10. Strotmeyer, E. S., et al (2006) Middle-aged premenopausal women with type 1 diabetes have lower bone mineral density and calcaneal quantitative ultrasound than nondiabetic women. Diabetes Care 29(2):306-311
11. Miao J., et al (2005) Elevated hip fracture risk in type 1 diabetic patients: a population- based cohort study in Sweden. Diabetes Care 28(12):2850-2855
12. Hofbauer L. C., et al (2007) Osteoporosis in patients with diabetes mellitus. J Bone Miner Res 22(9):1317-1328
13. Rees D. A., Alcolado JC (2005) Animal models of diabetes mellitus. Diabet Med 22(4):359-370
14. Szkudelski, T. (2001) The mechanism of alloxan and streptozotocin action in B cells of the rat pancreas. Physiol Res 50(6):537-546
15. Reddy, S., Wu D., Elliott, R. B. (1995) Low dose streptozotocin causes diabetes in severe combined immunodeficient (SCID) mice without immune cell infiltration of the pancreatic islets. Autoimmunity 20(2):83-92
16. Botolin, S., et al (2005) Increased bone adiposity and peroxisomal proliferator-activated receptor-gamma2 expression in type I diabetic mice. Endocrinology 146(8):3622-3631
17. Botolin, S., McCabe L. R. (2007) Bone loss and increased bone adiposity in spontaneous and pharmacologically induced diabetic mice. Endocrinology 148(1):198-205
18. Pechhold, K., et al (2001) Low dose streptozotocin- induced diabetes in rat insulin promoter-mCD80-transgenic mice is T cell autoantigen-specific and CD28 dependent. J Immunol 166(4):2531-2539
19. Ontiveros, C., McCabe, L. R. (2003) Simulated microgravity suppresses osteoblast phe- notype, Runx2 levels and AP-1 transactivation. J Cell Biochem88(3):427-437
20. Li, J., et al (2003) Insig-1 "brakes" lipogenesis in adipocytes and inhibits differentiation of preadipocytes. Proc Natl Acad Sci USA 100(16):9476-981
21. Wiren, K. M., et al (2004) Targeted overexpression of androgen receptor in osteob l a s t s : unexpected comp l ex bone phenotype in growing animals. Endocrinology 145(7):3507-3522
22. Yoshimatsu, M., et al (2006) Experimental model of tooth movement by orthodontic force in mice and its application to tumor necrosis factor receptor-deficient mice. J Bone Miner Metab 24(1):20-27
23. Zhao, S., et al (2002)MLO-Y4 osteocyte-like cells support osteoclast formation and activation. J Bone Miner Res 17(11):2068-2079
24. Xue, M. L., Thakur, A., Willcox, M., (2002) Gene expression of pro-inflammatory cytokines and chemokines in mouse eye infected with Pseudomonas aeruginosa. Clin Experiment Ophthalmol 30(3):196-199
25. Junod, A., et al (1969) Diabetogenic action of streptozotocin: relationship of dose to metabolic response. J Clin Invest 48 (11):2129-2139
26. Lu, W. T., et al (1998) Effects of high or low dose of streptozocin on pancreatic islets in C57BL/6 and C.B17-SCID mice. Transplant Proc 30(2):609-610
27. 2+ in ventricular myocytes from diabetes resistant and susceptible rats. Mol Cell Biochem 269(1-2):103-108
28. Saini, K. S., et al (1996) Streptozotocin at low doses induces apoptosis and at high doses causes necrosis in a murine pancreatic beta cell line, INS-1. Biochem Mol Biol Int 39(6):1229-1236
29. Van Dam, P. S., et al (1999) Nerve conduction and antioxidant levels in experimen tal ly d iabet ic r a t s : ef f ect s o f streptozotocin dose and diabetes duration. Metabolism 48(4):442-447
30. Szkudelski, T., Szkudelska, K. (2002) Streptozotocin induces lipolysis in rat adipocytes in vitro. Physiol Res 51(3):255-259
31. Epstein, S., et al (1994) Effect of cyclosporin A on bone mineral metabolism in experimental diabetes mellitus in the rat. J Bone Miner Res 9(4):557-566
32. Goodman,W.G., Hori,M.T. (1984) Diminished bone formation in experimental diabetes. Relationship to osteoid maturation and mineralization. Diabetes 33(9):825-831
33. Horcajada-Molteni, M. N., et al (2001) Amylin and bone metabolism in streptozotocin- induced diabetic rats. J Bone Miner Res 16(5):958-965
34. Hough, S., et al (1981) Correction of abnormal bone and mineral metabolism in chronic streptozotocin-induced diabetes mellitus in the rat by insulin therapy. Endocrinology 108(6):2228-2234
35. Katayama, Y., et al (1996) Role of nonenzymatic glycosylation of type I collagen in diabetic osteopenia. J Bone MinerRes 11(7):931-937
36. Lu, H., et al (2003) Diabetes interferes with the bone formation by affecting the expression of transcription factors that regulate osteoblast differentiation. Endocrinology 144(1):346-352
37. Martin, L. M., McCabe, L. R. (2007) Type I diabetic bone phenotype is location but not gender dependent. Histochem Cell Biol 128(2):125-133
38. Alexopoulou, O., et al (2006) Bone density and markers of bone remodeling in type 1 male diabetic patients. Diabetes Metab 32 (5 Pt 1):453-458
39. Bouillon, R. (1991) Diabetic bone disease [editorial]. Calcif Tissue Int 49(3):155-160
40. Gunczler, P., et al (1998) Decreased lumbar spine bone mass and low bone turnover in children and adolescents with insulin dependent diabetes mellitus followed longitudinally. J Pediatr Endocrinol Metab 11(3):413-419
41. Lopez-Ibarra, P. J., et al (2001) Bone mineral density at time of clinical diagnosis of adult-onset type 1 diabetes mellitus. Endocr Pract 7(5):346-351
42. Thrailkill, K. M., et al (2005) Bone formation is impaired in a model of type 1 diabetes. Diabetes 54(10):2875-2881
43. Verhaeghe, J., et al (1989) Bone mineral homeostasis in spontaneously diabetic BB rats. II. Impaired bone turnover and decreased osteocalcin synthesis. Endocrinology 124(2):573-582
44. Verhaeghe, J., et al (1997) Decreased osteoblast activity in spontaneously diabetic rats. In vivo studies on the pathogenesis. Endocrine 7(2):165-175
45. Verhaeghe, J., et al (1990) Bone and mineral metabolism in BB rats with long-term diabetes. Decreased bone turnover and osteoporosis. Diabetes 39(4):477-482
46. Verhaeghe, J., et al (1990) Osteoporosis and diabetes: lessons from the diabetic BB rat. Horm Res 34(5-6):245-248
47. Waud, C. E., et al (1994) Bone mineral density in the femur and lumbar vertebrae decreases after twelve weeks of diabetes in spontaneously diabetic-prone BB/Worcester rats. Calcif Tissue Int 54(3):237-240
48. Yoon, J. W., Reddi, A. H. (1984) Decreased bone formation and mineralization in virus-induced diabetes mellitus. Am J Physiol 246(1 Pt 1):C177-C179
49. McCabe, L. R. (2007)Understanding the pathology and mechanisms of type I diabetic bone loss. J Cell Biochem102(6):1343-1357
50. Hamada, Y., et al (2007)Histomorphometric analysis of diabetic osteopenia in streptozotocin- induced diabetic mice: a possible role of oxidative stress. Bone 40(5):1408-1414
51. Botolin, S., McCabe, L. R. (2006) Inhibition of PPARgamma prevents type I diabetic bone marrow adiposity but not bone loss. J Cell Physiol 209(3):967-976
52. Motyl, K., et al (2009) Bone inflammation and altered gene expression with type I diabetes early onset. J Cell Physiol 218:575-583
53. Cakatay, U., et al (1998) Changes in bone turnover on deoxypyridinoline levels in diabetic patients. Diabetes Res Clin Pract 40 (2):75-79
54. Mishima, N., et al (2002) Effect of streptozotocin- induced diabetes mellitus on alveolar bone deposition in the rat. Arch Oral Biol 47(12):843-849
55. He, H., et al (2004) Diabetes causes decreased osteoclastogenesis, reduced bone formation, and enhanced apoptosis of osteoblastic cells in bacteria stimulated bone loss. Endocrinology 145(1):447-452
56. Locatto, M. E., et al (1993) Growth and development of bone mass in untreated alloxan diabetic rats. Effects of collagen glycosylation and parathyroid activity on bone turnover. Bone Miner 23(2):129-144
57. Herrero, S., et al (1998) Low bone density with normal bone turnover in ovariectomized and streptozotocin-induced diabetic rats. Calcif Tissue Int 62(3):260-265
58. Verhaeghe, J., et al (2000) Effects of exercise and disuse on bone remodeling, bone mass, and biomechanical competence in spontaneously diabetic female rats. Bone 27(2):249-256
59. Halleen, J. M., et al (2000) Tartrate-resistant acid phosphatase 5b: a novel serum marker of bone resorption. J Bone Miner Res 15(7):1337-1345
60. Halleen, J. M., et al (2002) Serum tartrateresistant acid phosphatase 5b, but not 5a, correlates with other markers of bone turnover and bone mineral density. Calcif Tissue Int 71(1):20-25
61. Bonfanti, R., et al (1997) Bone modeling indexes at onset and during the first year of follow-Up in insulin-dependent diabetic children. Calcif Tissue Int 60(5):397-400
62. Valerio, G., et al (2002) The lumbar bone mineral density is affected by long-term poor metabolic control in adolescents with type 1 diabetes mellitus. Horm Res 58(6):266-272
63. Cloos, C., et al (1998) Urinary glycosylated, free and total pyridinoline and free and total deoxypyridinoline in diabetes mellitus. Clin Endocrinol (Oxf) 48(3):317-323
64. Wittrant, Y., et al (2008) High d(+)glucose concentration inhibits RANKL-induced osteoclastogenesis. Bone 42:1122-1130
65. Valcourt, U., et al (2007) Non-enzymatic glycation of bone collagen modifies osteoclastic activity and differentiation. J Biol Chem 282(8):5691-5703
66. Ding, K. H., et al (2006) Disordered osteoclast formation in RAGE-deficient mouse establishes an essential role for RAGE in diabetes related bone loss. Biochem Biophys Res Commun 340(4):1091-1097
67. Hie, M., et al (2007) Increased cathepsin K and tartrate-resistant acid phosphatase expression in bone of streptozotocin-induced diabetic rats. Bone 41(6):1045-1050
68. Motyl, K., McCabe, L., (2008) Leptin treatment prevents type I diabetic marrow adiposity but not bone loss in mice. J Cell Physiol 218:376-384
69. Wasan, K. M., et al (1998) Streptozotocinand alloxan-induced diabetes modifies total plasma and lipoprotein lipid concentration and composition without altering cholesteryl ester transfer activity. Pharmacol Toxicol 83(4):169-175
70. Koulmanda, M., et al (2003) The effect of low versus high dose of streptozotocin in cynomolgus monkeys (Macaca fascilularis). Am J Transplant 3(3):267-272
71. Andress, D. L., (2008) Adynamic bone in patients with chronic kidney disease. Kidney Int 73(12):1345-1354
72. Wainford, R. D., et al (2008) Cisplatin nephrotoxicity is mediated by gamma glutamyltranspeptidase, not via a C-S lyase governed biotransformation pathway. Toxicology 249(2-3):184-193
73. Lacour, S., et al (2005) Cytokines as potential biomarkers of liver toxicity. Cancer Biomark 1(1):29-39.