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Volumn 29, Issue 11-12, 2013, Pages 1388-1394

Distinct effects of leucine or a mixture of the branched-chain amino acids (leucine, isoleucine, and valine) supplementation on resistance to fatigue, and muscle and liver-glycogen degradation, in trained rats

Author keywords

BCAAS supplementation; Intense exercise; Leucine; Liver and muscle glycogen; Tricarboxylic acid cycle intermediates

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; BRANCHED CHAIN AMINO ACID AMINOTRANSFERASE; CITRATE SYNTHASE; CITRIC ACID; GLYCOGEN; ISOLEUCINE; LEUCINE; MALIC ACID; PLACEBO; VALINE;

EID: 84884928903     PISSN: 08999007     EISSN: 18731244     Source Type: Journal    
DOI: 10.1016/j.nut.2013.05.003     Document Type: Article
Times cited : (39)

References (46)
  • 1
    • 0014019269 scopus 로고
    • Muscle glycogen synthesis after exercise: an enhancing factor localized to the muscle cells in man
    • Bergstrom J., Hultman E. Muscle glycogen synthesis after exercise: an enhancing factor localized to the muscle cells in man. Nature 1966, 210:309-310.
    • (1966) Nature , vol.210 , pp. 309-310
    • Bergstrom, J.1    Hultman, E.2
  • 2
    • 0013873817 scopus 로고    scopus 로고
    • The effect of exercise on muscle glycogen and electrolytes in normals
    • Bergstrom J., Hultman E. The effect of exercise on muscle glycogen and electrolytes in normals. Scand J Clin Lab Invest 1996, 18:16-20.
    • (1996) Scand J Clin Lab Invest , vol.18 , pp. 16-20
    • Bergstrom, J.1    Hultman, E.2
  • 3
    • 0028892992 scopus 로고
    • Influence of muscle glycogen on glycogenolysis and glucose uptake during exercise in humans
    • Hargreaves M., McConell G., Proietto J. Influence of muscle glycogen on glycogenolysis and glucose uptake during exercise in humans. J Appl Physiol 1995, 78:288-292.
    • (1995) J Appl Physiol , vol.78 , pp. 288-292
    • Hargreaves, M.1    McConell, G.2    Proietto, J.3
  • 4
    • 33744933166 scopus 로고    scopus 로고
    • Carbohydrate metabolism during prolonged exercise and recovery: interactions between pyruvate dehydrogenase, fatty acids, and amino acids
    • Mourtzakis M., Saltin B., Graham T., Pilegaard H. Carbohydrate metabolism during prolonged exercise and recovery: interactions between pyruvate dehydrogenase, fatty acids, and amino acids. J Appl Physiol 2006, 100:1822-1830.
    • (2006) J Appl Physiol , vol.100 , pp. 1822-1830
    • Mourtzakis, M.1    Saltin, B.2    Graham, T.3    Pilegaard, H.4
  • 5
    • 84861910413 scopus 로고    scopus 로고
    • More than a store: regulatory roles for glycogen in skeletal muscle adaptation to exercise
    • Philp A., Hargreaves M., Baar K. More than a store: regulatory roles for glycogen in skeletal muscle adaptation to exercise. Am J Physiol Endocrinol Metab 2012, 302:E1343-E1351.
    • (2012) Am J Physiol Endocrinol Metab , vol.302
    • Philp, A.1    Hargreaves, M.2    Baar, K.3
  • 6
    • 33645996993 scopus 로고    scopus 로고
    • Effects of leucine supplementation on the body composition and protein status of rats submitted to food restriction
    • Donato J., Pedrosa R.G., Cruzat V.F., Pires I.S., Tirapegui J. Effects of leucine supplementation on the body composition and protein status of rats submitted to food restriction. Nutrition 2006, 22:520-527.
    • (2006) Nutrition , vol.22 , pp. 520-527
    • Donato, J.1    Pedrosa, R.G.2    Cruzat, V.F.3    Pires, I.S.4    Tirapegui, J.5
  • 7
    • 84870579854 scopus 로고    scopus 로고
    • Effects of diets supplemented with branched-chain amino acids on the performance and fatigue mechanisms of rats submitted to prolonged physical exercise
    • Falavigna G., Alves de Araújo J., Rogero M.M., Pires I.S., Pedrosa R.G., Martins E., et al. Effects of diets supplemented with branched-chain amino acids on the performance and fatigue mechanisms of rats submitted to prolonged physical exercise. Nutrients 2012, 4:1767-1780.
    • (2012) Nutrients , vol.4 , pp. 1767-1780
    • Falavigna, G.1    Alves de Araújo, J.2    Rogero, M.M.3    Pires, I.S.4    Pedrosa, R.G.5    Martins, E.6
  • 9
    • 80053124740 scopus 로고    scopus 로고
    • Branched-chain amino acids, mitochondrial biogenesis, and healthspan: an evolutionary perspective
    • Valerio A., D'Antona G., Nisoli E. Branched-chain amino acids, mitochondrial biogenesis, and healthspan: an evolutionary perspective. Aging (Albany NY) 2011, 3:464-478.
    • (2011) Aging (Albany NY) , vol.3 , pp. 464-478
    • Valerio, A.1    D'Antona, G.2    Nisoli, E.3
  • 11
    • 31544458134 scopus 로고    scopus 로고
    • Branched-chain amino acids: enzyme and substrate regulation
    • Brosnan J.T., Brosnan M.E. Branched-chain amino acids: enzyme and substrate regulation. J Nutr 2006, 136:207S-211S.
    • (2006) J Nutr , vol.136
    • Brosnan, J.T.1    Brosnan, M.E.2
  • 12
    • 0031626826 scopus 로고    scopus 로고
    • Muscle amino acid metabolism at rest and during exercise: role in human physiology and metabolism
    • Wagenmakers A.J. Muscle amino acid metabolism at rest and during exercise: role in human physiology and metabolism. Exerc Sport Sci Rev 1998, 26:287-314.
    • (1998) Exerc Sport Sci Rev , vol.26 , pp. 287-314
    • Wagenmakers, A.J.1
  • 13
    • 31544440119 scopus 로고    scopus 로고
    • Potential importance of leucine in treatment of obesity and the metabolic syndrome
    • Layman D.K., Walker D.A. Potential importance of leucine in treatment of obesity and the metabolic syndrome. J Nutr 2006, 136:319S-323S.
    • (2006) J Nutr , vol.136
    • Layman, D.K.1    Walker, D.A.2
  • 14
    • 0037224768 scopus 로고    scopus 로고
    • The role of leucine in weight loss diets and glucose homeostasis."
    • Layman D.K. The role of leucine in weight loss diets and glucose homeostasis.". J Nutr 2003, 133:261S-267S.
    • (2003) J Nutr , vol.133
    • Layman, D.K.1
  • 15
    • 84858293594 scopus 로고    scopus 로고
    • Effects of leucine supplementation and resistance exercise on dexamethasone-induced muscle atrophy and insulin resistance in rats
    • Nicastro H., Zanchi N.E., da Luz C.R., de Moraes W.M., Ramona P., de Siqueira Filho M.A., et al. Effects of leucine supplementation and resistance exercise on dexamethasone-induced muscle atrophy and insulin resistance in rats. Nutrition 2012, 28:465-471.
    • (2012) Nutrition , vol.28 , pp. 465-471
    • Nicastro, H.1    Zanchi, N.E.2    da Luz, C.R.3    de Moraes, W.M.4    Ramona, P.5    de Siqueira Filho, M.A.6
  • 16
    • 84873802152 scopus 로고    scopus 로고
    • Does branched-chain amino acids supplementation modulate skeletal muscle remodeling through inflammation modulation? Possible mechanisms of action
    • Nicastro H., da Luz C.R., Chaves D.F., Bechara L.R., Voltarelli V.A., Rogero M.M., et al. Does branched-chain amino acids supplementation modulate skeletal muscle remodeling through inflammation modulation? Possible mechanisms of action. J Nutr Metab 2012, 2012:136937.
    • (2012) J Nutr Metab , vol.2012 , pp. 136937
    • Nicastro, H.1    da Luz, C.R.2    Chaves, D.F.3    Bechara, L.R.4    Voltarelli, V.A.5    Rogero, M.M.6
  • 17
    • 0036903686 scopus 로고    scopus 로고
    • Dissociation between muscle tricarboxylic acid cycle pool size and aerobic energy provision during prolonged exercise in humans
    • Gibala M.J., Gonzalez-Alonso J., Saltin B. Dissociation between muscle tricarboxylic acid cycle pool size and aerobic energy provision during prolonged exercise in humans. J Physiol 2002, 545:705-713.
    • (2002) J Physiol , vol.545 , pp. 705-713
    • Gibala, M.J.1    Gonzalez-Alonso, J.2    Saltin, B.3
  • 18
    • 53449087473 scopus 로고    scopus 로고
    • Glutamate availability is important in intramuscular amino acid metabolism and TCA cycle intermediates but does not affect peak oxidative metabolism
    • Mourtzakis M., Graham T.E., González-Alonso J., Saltin B. Glutamate availability is important in intramuscular amino acid metabolism and TCA cycle intermediates but does not affect peak oxidative metabolism. J Appl Physiol 2008, 105:547-554.
    • (2008) J Appl Physiol , vol.105 , pp. 547-554
    • Mourtzakis, M.1    Graham, T.E.2    González-Alonso, J.3    Saltin, B.4
  • 19
    • 36348999715 scopus 로고    scopus 로고
    • Tricarboxylic acid cycle intermediate pool size: functional importance for oxidative metabolism in exercising human skeletal muscle
    • Bowtell J.L., Marwood S., Bruce M., Constantin-Teodosiu D., Greenhaff P.L. Tricarboxylic acid cycle intermediate pool size: functional importance for oxidative metabolism in exercising human skeletal muscle. Sports Med 2007, 37:1071-1088.
    • (2007) Sports Med , vol.37 , pp. 1071-1088
    • Bowtell, J.L.1    Marwood, S.2    Bruce, M.3    Constantin-Teodosiu, D.4    Greenhaff, P.L.5
  • 20
    • 9244229559 scopus 로고    scopus 로고
    • Effects of 7 wk of endurance training on human skeletal muscle metabolism during submaximal exercise
    • Leblanc P.J., Howarth K.R., Gibala M.J., Heigenhauser G.J. Effects of 7 wk of endurance training on human skeletal muscle metabolism during submaximal exercise. J Appl Physiol 2004, 97:2148-2153.
    • (2004) J Appl Physiol , vol.97 , pp. 2148-2153
    • Leblanc, P.J.1    Howarth, K.R.2    Gibala, M.J.3    Heigenhauser, G.J.4
  • 21
    • 79955093729 scopus 로고    scopus 로고
    • Branched-chain amino acids supplementation enhances exercise capacity and lipid oxidation during endurance exercise after muscle glycogen depletion
    • Gualano A.B., Bozza T., Lopes De Campos P., Roschel H., Dos Santos Costa A., Luiz Marquezi M., et al. Branched-chain amino acids supplementation enhances exercise capacity and lipid oxidation during endurance exercise after muscle glycogen depletion. J Sports Med Phys Fitness 2011, 51:82-88.
    • (2011) J Sports Med Phys Fitness , vol.51 , pp. 82-88
    • Gualano, A.B.1    Bozza, T.2    Lopes De Campos, P.3    Roschel, H.4    Dos Santos Costa, A.5    Luiz Marquezi, M.6
  • 23
    • 0028209943 scopus 로고
    • Pyruvate carboxylase activity in the heart and skeletal muscles of the rat. Evidence for a stimulating effect of exercise
    • Lancha A.H., Recco M.B., Curi R. Pyruvate carboxylase activity in the heart and skeletal muscles of the rat. Evidence for a stimulating effect of exercise. Biochem Mol Biol Int 1994, 32:483-489.
    • (1994) Biochem Mol Biol Int , vol.32 , pp. 483-489
    • Lancha, A.H.1    Recco, M.B.2    Curi, R.3
  • 25
    • 0024379317 scopus 로고
    • A theoretical basis for increasing current estimates of the amino acid requirements in adult man, with experimental support
    • Young V.R., Bier D.M., Pellett P.L. A theoretical basis for increasing current estimates of the amino acid requirements in adult man, with experimental support. Am J Clin Nutr 1989, 50:80-92.
    • (1989) Am J Clin Nutr , vol.50 , pp. 80-92
    • Young, V.R.1    Bier, D.M.2    Pellett, P.L.3
  • 26
    • 38949167771 scopus 로고    scopus 로고
    • Indicator amino acid oxidation: concept and application
    • Elango R., Ball R.O., Pencharz P.B. Indicator amino acid oxidation: concept and application. J Nutr 2008, 138:243-246.
    • (2008) J Nutr , vol.138 , pp. 243-246
    • Elango, R.1    Ball, R.O.2    Pencharz, P.B.3
  • 28
    • 0028897034 scopus 로고
    • Effect of aspartate, asparagine, and carnitine supplementation in the diet on metabolism of skeletal muscle during a moderate exercise
    • Lancha A.H., Recco M.B., Abdalla D.S., Curi R. Effect of aspartate, asparagine, and carnitine supplementation in the diet on metabolism of skeletal muscle during a moderate exercise. Physiol Behav 1995, 57:367-371.
    • (1995) Physiol Behav , vol.57 , pp. 367-371
    • Lancha, A.H.1    Recco, M.B.2    Abdalla, D.S.3    Curi, R.4
  • 29
    • 0017307551 scopus 로고
    • IFCC method for aspartate aminotransferase. Appendix B. Conditions for the measurement of the catalytic concentrations of reagent enzymes and the contaminants
    • Bergmeyer H.U., Bowers G.N., Horder M., Moss D.W. IFCC method for aspartate aminotransferase. Appendix B. Conditions for the measurement of the catalytic concentrations of reagent enzymes and the contaminants. Clin Chim Acta 1976, 70:F41-F42.
    • (1976) Clin Chim Acta , vol.70
    • Bergmeyer, H.U.1    Bowers, G.N.2    Horder, M.3    Moss, D.W.4
  • 30
    • 0023883816 scopus 로고
    • Influence of dietary leucine content on the activities of branched-chain amino acid aminotransferase (EC 2.6.1.42) and branched-chain alpha-keto acid dehydrogenase (EC 1.2.4.4) complex in tissues of preruminant lambs
    • Papet I., Lezebot N., Barre F., Arnal M., Harper A.E. Influence of dietary leucine content on the activities of branched-chain amino acid aminotransferase (EC 2.6.1.42) and branched-chain alpha-keto acid dehydrogenase (EC 1.2.4.4) complex in tissues of preruminant lambs. Br J Nutr 1988, 59:475-483.
    • (1988) Br J Nutr , vol.59 , pp. 475-483
    • Papet, I.1    Lezebot, N.2    Barre, F.3    Arnal, M.4    Harper, A.E.5
  • 32
    • 0026600946 scopus 로고
    • Quantitative analysis of amino acid oxidation and related gluconeogenesis in humans
    • Jungas R.L., Halperin M.L., Brosnan J.T. Quantitative analysis of amino acid oxidation and related gluconeogenesis in humans. Physiol Rev 1992, 72:419-448.
    • (1992) Physiol Rev , vol.72 , pp. 419-448
    • Jungas, R.L.1    Halperin, M.L.2    Brosnan, J.T.3
  • 33
    • 0033834961 scopus 로고    scopus 로고
    • Protein and amino acid metabolism during and after exercise and the effects of nutrition
    • Rennie M.J., Tipton K.D. Protein and amino acid metabolism during and after exercise and the effects of nutrition. Annu Rev Nutr 2000, 20:457-483.
    • (2000) Annu Rev Nutr , vol.20 , pp. 457-483
    • Rennie, M.J.1    Tipton, K.D.2
  • 34
    • 20344373417 scopus 로고    scopus 로고
    • Overview of the molecular and biochemical basis of branched-chain amino acid catabolism
    • Harris R.A., Joshi M., Jeoung N.H., Obayashi M. Overview of the molecular and biochemical basis of branched-chain amino acid catabolism. J Nutr 2005, 135:1527S-1530S.
    • (2005) J Nutr , vol.135
    • Harris, R.A.1    Joshi, M.2    Jeoung, N.H.3    Obayashi, M.4
  • 35
    • 0035744467 scopus 로고    scopus 로고
    • Regulation of branched-chain amino acid catabolism: nutritional and hormonal regulation of activity and expression of the branched-chain alpha-keto acid dehydrogenase kinase
    • Shimomura Y., Obayashi M., Murakami T., Harris R.A. Regulation of branched-chain amino acid catabolism: nutritional and hormonal regulation of activity and expression of the branched-chain alpha-keto acid dehydrogenase kinase. Curr Opin Clin Nutr Metab Care 2001, 4:419-423.
    • (2001) Curr Opin Clin Nutr Metab Care , vol.4 , pp. 419-423
    • Shimomura, Y.1    Obayashi, M.2    Murakami, T.3    Harris, R.A.4
  • 36
    • 77950555096 scopus 로고    scopus 로고
    • Disruption of BCAA metabolism in mice impairs exercise metabolism and endurance
    • She P., Zhou Y., Zhang Z., Griffin K., Gowda K., Lynch C.J. Disruption of BCAA metabolism in mice impairs exercise metabolism and endurance. J Appl Physiol 2010, 108:941-949.
    • (2010) J Appl Physiol , vol.108 , pp. 941-949
    • She, P.1    Zhou, Y.2    Zhang, Z.3    Griffin, K.4    Gowda, K.5    Lynch, C.J.6
  • 37
    • 0026494762 scopus 로고
    • Amino acid metabolism, muscular fatigue and muscle wasting. Speculations on adaptations at high altitude
    • Wagenmakers A.J. Amino acid metabolism, muscular fatigue and muscle wasting. Speculations on adaptations at high altitude. Int J Sports Med 1992, 13:S110-S113.
    • (1992) Int J Sports Med , vol.13
    • Wagenmakers, A.J.1
  • 38
    • 2642562073 scopus 로고    scopus 로고
    • Exercise promotes BCAA catabolism: effects of BCAA supplementation on skeletal muscle during exercise
    • Shimomura Y., Murakami T., Nakai N., Nagasaki M., Harris R.A. Exercise promotes BCAA catabolism: effects of BCAA supplementation on skeletal muscle during exercise. J Nutr 2004, 134:1583S-1587S.
    • (2004) J Nutr , vol.134
    • Shimomura, Y.1    Murakami, T.2    Nakai, N.3    Nagasaki, M.4    Harris, R.A.5
  • 39
    • 0032802276 scopus 로고    scopus 로고
    • Hepatic branched-chain alpha-keto acid dehydrogenase complex in female rats: activation by exercise and starvation
    • Kobayashi R., Shimomura Y., Murakami T., Nakai N., Otsuka M., Arakawa N., et al. Hepatic branched-chain alpha-keto acid dehydrogenase complex in female rats: activation by exercise and starvation. J Nutr Sci Vitaminol (Tokyo) 1999, 45:303-309.
    • (1999) J Nutr Sci Vitaminol (Tokyo) , vol.45 , pp. 303-309
    • Kobayashi, R.1    Shimomura, Y.2    Murakami, T.3    Nakai, N.4    Otsuka, M.5    Arakawa, N.6
  • 40
    • 0033848734 scopus 로고    scopus 로고
    • Regulation of branched-chain alpha-keto acid dehydrogenase kinase gene expression by glucocorticoids in hepatoma cells and rat liver
    • Huang Y.S., Chuang D.T. Regulation of branched-chain alpha-keto acid dehydrogenase kinase gene expression by glucocorticoids in hepatoma cells and rat liver. Methods Enzymol 2000, 324:498-511.
    • (2000) Methods Enzymol , vol.324 , pp. 498-511
    • Huang, Y.S.1    Chuang, D.T.2
  • 41
    • 0035091117 scopus 로고    scopus 로고
    • Regulation of branched-chain alpha-keto acid dehydrogenase kinase expression in rat liver
    • Harris R.A., Kobayashi R., Murakami T., Shimomura Y. Regulation of branched-chain alpha-keto acid dehydrogenase kinase expression in rat liver. J Nutr 2001, 131:841S-845S.
    • (2001) J Nutr , vol.131
    • Harris, R.A.1    Kobayashi, R.2    Murakami, T.3    Shimomura, Y.4
  • 42
    • 0032706540 scopus 로고    scopus 로고
    • Low glycogen and branched-chain amino acid ingestion do not impair anaplerosis during exercise in humans
    • Gibala M.J., Lozej M., Tarnopolsky M.A., McLean C., Graham T.E. Low glycogen and branched-chain amino acid ingestion do not impair anaplerosis during exercise in humans. J Appl Physiol 1999, 87:1662-1667.
    • (1999) J Appl Physiol , vol.87 , pp. 1662-1667
    • Gibala, M.J.1    Lozej, M.2    Tarnopolsky, M.A.3    McLean, C.4    Graham, T.E.5
  • 43
    • 84862528570 scopus 로고    scopus 로고
    • Effects of alanine aminotransferase inhibition on the intermediary metabolism in Sparus aurata through dietary amino-oxyacetate supplementation
    • González J.D., Caballero A., Viegas I., Metón I., Jones J.G., Barra J., et al. Effects of alanine aminotransferase inhibition on the intermediary metabolism in Sparus aurata through dietary amino-oxyacetate supplementation. Br J Nutr 2012, 107:1747-1756.
    • (2012) Br J Nutr , vol.107 , pp. 1747-1756
    • González, J.D.1    Caballero, A.2    Viegas, I.3    Metón, I.4    Jones, J.G.5    Barra, J.6
  • 45
    • 79952201213 scopus 로고    scopus 로고
    • Increased ratio of dietary carbohydrate to protein shifts the focus of metabolic signaling from skeletal muscle to adipose
    • Devkota S., Layman D.K. Increased ratio of dietary carbohydrate to protein shifts the focus of metabolic signaling from skeletal muscle to adipose. Nutr Metab (Lond) 2011, 8:13.
    • (2011) Nutr Metab (Lond) , vol.8 , pp. 13
    • Devkota, S.1    Layman, D.K.2
  • 46
    • 78651293205 scopus 로고    scopus 로고
    • Potential role of branched-chain amino acids in glucose metabolism through the accelerated induction of the glucose-sensing apparatus in the liver
    • Higuchi N., Kato M., Miyazaki M., Tanaka M., Kohjima M., Ito T., et al. Potential role of branched-chain amino acids in glucose metabolism through the accelerated induction of the glucose-sensing apparatus in the liver. J Cell Biochem 2011, 112:30-38.
    • (2011) J Cell Biochem , vol.112 , pp. 30-38
    • Higuchi, N.1    Kato, M.2    Miyazaki, M.3    Tanaka, M.4    Kohjima, M.5    Ito, T.6


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