Interactions between Social/ behavioral factors and ADRB2 genotypes may be associated with health at advanced ages in China

BMC Geriatrics

Volumn 13, Issue 1, 2013, Pages

  Zeng, Yi ^a,b   Cheng, Lingguo ^c   Zhao, Ling ^d   Tan, Qihua ^e   Feng, Qiushi ^f   Chen, Huashuai ^a,g   Shen, Ke ^h   Li, Jianxin ^b,d   Zhang, Fengyu ⁱ   Cao, Huiqing ^d   Gregory, Simon G ^a   Yang, Ze ^j   Gu, Jun ^d   Tao, Wei ^d   Tian, Xiao Li ^d   Hauser, Elizabeth R ^a  

^a DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b DUKE UNIVERSITY   (United States)

^c NANJING UNIVERSITY   (China)

^d PEKING UNIVERSITY   (China)

^e UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

^f NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^g XIANGTAN UNIVERSITY   (China)

^h FUDAN UNIVERSITY   (China)

ⁱ NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

^j BEIJING HOSPITAL   (China)

more..

Author keywords

ADRB2 genotypes; Cognitive function; GxE Interactions; Health aging; Negative emotion; Oldest old; Regular exercise; Self reported health; Social leisure activities; Social behavioral factors

Indexed keywords

ADRB2 PROTEIN, HUMAN; BETA 2 ADRENERGIC RECEPTOR;

AGING; ARTICLE; ASIAN; CHINA; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; ETHNOLOGY; FEMALE; GENETICS; GENOTYPE; HEALTH STATUS; HEALTH SURVEY; HUMAN; LONGITUDINAL STUDY; MALE; METHODOLOGY; RANDOMIZED CONTROLLED TRIAL; SOCIAL BEHAVIOR; VERY ELDERLY;

AGED, 80 AND OVER; AGING; ASIAN CONTINENTAL ANCESTRY GROUP; CHINA; FEMALE; GENOTYPE; HEALTH STATUS; HEALTH SURVEYS; HUMANS; LONGITUDINAL STUDIES; MALE; RECEPTORS, ADRENERGIC, BETA-2; SOCIAL BEHAVIOR;

EID: 84884921454     PISSN: None     EISSN: 14712318     Source Type: Journal    
DOI: 10.1186/1471-2318-13-91     Document Type: Article

References (61)

1. Vascular smooth muscle cell-selective peroxisome proliferator-activated receptor-γ deletion leads to hypotension. Chang L, Villacorta L, Zhang J, Garcia-Barrio MT, Yang K, Hamblin M, Whitesall SE, D'Alecy LG, Chen YE, Circulation 2009 119 16 2161 2169 10.1161/CIRCULATIONAHA.108.815803 19364979
2. Extracellular ubiquitin inhibits beta-AR-stimulated apoptosis in cardiac myocytes: role of GSK-3beta and mitochondrial pathways. Singh M, Roginskaya M, Dalal S, Menon B, Kaverina E, Boluyt MO, Singh K, Cardiovasc Res 2010 86 1 20 28 10.1093/cvr/cvp402 20015977
3. Polymorphism in the beta2-adrenergic receptor and lipoprotein lipase genes as risk determinants for idiopathic venous thromboembolism: a multilocus, population-based, prospective genetic analysis. Zee RY, Cook NR, Cheng S, Erlich HA, Lindpaintner K, Ridker PM, Circulation 2006 113 18 2193 2200 10.1161/CIRCULATIONAHA.106.615401 16651467
4. β2ADR haplotypes/polymorphisms associate with bronchodilator response and total IgE in grass allergy. Woszczek G, Borowiec M, Ptasinska A, Kosinski S, Pawliczak R, Kowalski M, Allergy 2005 60 11 1412 1417 10.1111/j.1398-9995.2005.00869.x 16197474 (Pubitemid 41476185)
5. Type 5 adenylyl cyclase disruption increases longevity and protects against stress. Yan L, Vatner DE, O'Connor JP, Ivessa A, Ge H, Chen W, Hirotani S, Ishikawa Y, Sadoshima J, Vatner SF, Cell 2007 130 2 247 258 10.1016/j.cell.2007.05.038 17662940 (Pubitemid 47081133)
6. Beta2-adrenergic receptor gene polymorphisms as systemic determinants of healthy aging in an evolutionary context. Kulminski AM, Culminskaya I, Ukraintseva SV, Arbeev KG, Land KC, Yashin AI, Mech Ageing Dev 2010 131 5 338 345 10.1016/j.mad.2010.04.001 20399803
7. Polymorphisms in the ACE and ADRB2 genes and risks of aging-associated phenotypes: the case of myocardial infarction. Kulminski AM, Culminskaya IV, Ukraintseva SV, Arbeev KG, Akushevich I, Land KC, Yashin AI, Rejuvenation Res 2010 13 1 13 21 10.1089/rej.2009.0905 20230274
8. Common genetic variants of the beta2-adrenergic receptor affect its translational efficiency and are associated with human longevity. Zhao L, Yang F, Xu K, Cao H, Zheng GY, Zhang Y, Li J, Cui H, Chen X, Zhu Z, et al. Aging Cell 2012 11 6 1094 1101 10.1111/acel.12011 23020224
9. Evidence that decreased function of lymphocyte beta adrenoreceptors reflects regulatory and adaptive processes in panic disorder with agoraphobia. Maddock RJ, Carter CS, Magliozzi JR, Gietzen D, Am J Psychiatry 1993 150 8 1219 8392297
10. The relationship between hostility and beta-adrenergic receptor physiology in health young males. Suarez EC, Shiller AD, Kuhn CM, Schanberg S, Williams R, Zimmermann EA, Psychosom Med 1997 59 5 481 487 9316180 (Pubitemid 27422245)
11. Reduced sensitivity of lymphocyte beta-adrenergic receptors in patients with endogenous depression and psychomotor agitation. Mann JJ, Brown RP, Halper JP, Sweeney JA, Kocsis JH, Stokes PE, Bilezikian JP, New Engl J Med 1985 313 12 715 720 10.1056/NEJM198509193131202 2993884 (Pubitemid 15232424)
12. Psychological states and lymphocyte β-adrenergic receptor responsiveness. Yu BH, Dimsdale JE, Mills PJ, Neuropsychopharmacology 1999 21 1 147 152 10.1016/S0893-133X(98)00133-X 10379529 (Pubitemid 29253845)
13. Lymphocyte beta-adrenoreceptor density in patients with unipolar depression and normal controls. Magliozzi JR, Gietzen D, Maddock RJ, Haack D, Doran AR, Goodman T, Weiler PG, Biol Psychiat 1989 26 1 15 25 10.1016/0006-3223(89)90004-8 2541807 (Pubitemid 19139940)
14. β 2-Adrenergic receptor activation and genetic polymorphisms in autism: data from dizygotic twins. Connors SL, Crowell DE, Eberhart CG, Copeland J, Newschaffer CJ, Spence SJ, Zimmerman AW, J Child Neurol 2005 20 11 876 884 10.1177/08830738050200110401 16417856 (Pubitemid 43125264)
15. β2-Adrenergic receptor gene variants and risk for autism in the AGRE cohort. Cheslack-Postava K, Fallin M, Avramopoulos D, Connors S, Zimmerman A, Eberhart C, Newschaffer C, Mol Psychiatr 2007 12 3 283 291 (Pubitemid 46328509)
16. Binding of amyloid β peptide to β2 adrenergic receptor induces PKA-dependent AMPA receptor hyperactivity. Wang D, Govindaiah G, Liu R, De Arcangelis V, Cox CL, Xiang YK, FASEB J 2010 24 9 3511 3521 10.1096/fj.10-156661 20395454
17. Polymorphisms at the β2-adrenergic receptor gene influence Alzheimer's disease susceptibility. Yu JT, Tan L, Ou JR, Zhu JX, Liu K, Song JH, Sun YP, Brain Res 2008 1210 216 222 18423577
18. Effects of chronic stress on beta-adrenergic receptors in the homeless. Dimsdale JE, Mills P, Patterson T, Ziegler M, Dillon E, Psychosom Med 1994 56 4 290 295 7972610 (Pubitemid 24233888)
19. Three major haplotypes of the β2 adrenergic receptor define psychological profile, blood pressure, and the risk for development of a common musculoskeletal pain disorder. Diatchenko L, Anderson AD, Slade GD, Fillingim RB, Shabalina SA, Higgins TJ, Sama S, Belfer I, Goldman D, Max MB, Am J Med Genet B Neuropsychiatr Genet 2006 141 5 449 462 (Pubitemid 44024438)
20. Adrenoceptors on blood cells in patients with essential hypertension before and after mental stress. Graafsma SJ, van Tits LJ, van Heijst P, Reyenga J, Lenders JWM, de Miranda JFR, Thien T, J Hypertens 1989 7 7 519 524 10.1097/00004872-198907000-00002 2547867 (Pubitemid 19189573)
21. β2-adrenergic receptor genotype and survival among patients receiving β-blocker therapy after an acute coronary syndrome. Lanfear DE, Jones PG, Marsh S, Cresci S, McLeod HL, Spertus JA, JAMA 2005 294 12 1526 1533 10.1001/jama.294.12.1526 16189366 (Pubitemid 41362690)
22. [beta] 2-adrenergic receptor genotype predicts survival: implications and future directions. Lanfear DE, Spertus JA, McLeod HL, J Cardiovasc Nursing 2006 21 6 474 477 10.1097/00005082-200611000-00011
23. ADRB2 Arg16Gly polymorphism, lung function, and mortality: results from the atherosclerosis risk in communities study. Ferdinands JM, Mannino DM, Gwinn ML, Bray MS, PloS one 2007 2 3 289 10.1371/journal.pone.0000289 17356698
24. Gene expression signature of cigarette smoking and its role in lung adenocarcinoma development and survival. Landi MT, Dracheva T, Rotunno M, Figueroa JD, Liu H, Dasgupta A, Mann FE, Fukuoka J, Hames M, Bergen AW, PLoS One 2008 3 2 1651 10.1371/journal.pone.0001651 18297132 (Pubitemid 351865456)
25. Lack of association between adrenergic receptor genotypes and survival in heart failure patients treated with carvedilol or metoprolol. Sehnert AJ, Daniels SE, Elashoff M, Wingrove JA, Burrow CR, Horne B, Muhlestein JB, Donahue M, Liggett SB, Anderson JL, et al. J Am Coll Cardiol 2008 52 8 644 651 10.1016/j.jacc.2008.05.022 18702968
26. β2-adrenergic receptor gene polymorphism is associated with mortality in septic shock. Nakada T, Russell JA, Boyd JH, Aguirre-Hernandez R, Thain KR, Thair SA, Nakada E, McConechy M, Walley KR, Am J Resp Crit Care 2010 181 2 143 149 10.1164/rccm.200903-0332OC
27. Genetic influence on human lifespan and longevity. Hjelmborg JB, Iachine I, Skytthe A, Vaupel JW, McGue M, Koskenvuo M, Kaprio J, Pedersen NL, Christensen K, Human Genetics 2006 119 3 312 321 10.1007/s00439-006-0144-y 16463022
28. Mortality Differences by APOE Genotype Estimated From Demographic Synthesis. Ewbank DC, Genet Epidemiol 2002 22 146 155 10.1002/gepi.0164 11788960 (Pubitemid 34081488)
29. Zeng Y, Poston DL Jr, Vlosky DA, Gu D, Healthy longevity in China: demographic, socioeconomic, and psychological dimensions, Volume 20 Dordrecht, the Netherlands: Springer Publisher 2008
30. Functional capacity and self-evaluation of health and life of oldest old in China. Zeng Y, Vaupel JW, J Social Issues 2002 58 4 733 748 10.1111/1540-4560.00287 (Pubitemid 36141273)
31. The effect of age misreporting in China on the calculation of mortality rates at very high ages. Coale AJ, Li S, Demography 1991 28 2 293 301 10.2307/2061281 2070900
32. Age validation of Han Chinese centenarians. Wang Z, Zeng Y, Jeune B, Vaupel JW, Genus 1998 54 1/2 123 141 12321975
33. Zhongguo 2000 nian shaoshu minzu de nian ling dui ji he shu zi pian hao (Age structure and composition of the Chinese minorities in 2000). Poston DL, Luo H, Zhongguo Shaoshu Minzu Renkou (Chinese Minority Populations) 2004 19 3 9 15
34. "Mini-mental state": a practical method for grading the cognitive state of patients for the clinician. Folstein MF, Folstein SE, McHugh PR, J Psychiatr Res 1975 12 3 189 198 10.1016/0022-3956(75)90026-6 1202204
35. Comparison of rating scales for the diagnosis of dementia in adults with Down's syndrome. Deb S, Braganza J, J Intellect Disabil Res 1999 43 5 400 407 10546964 (Pubitemid 29495566)
36. Cognitive function in old and very old residents of a residential facility: Relationship to age, education, and dementia. Osterweil D, Mulford P, Syndulko K, Martin M, J Am Geriatr Soc 1994 42 7 766 773 8014354 (Pubitemid 24213200)
37. Inequalities in self-rated health: explanations from different stages of life. Power C, Matthews S, Manor O, Lancet 1998 351 9108 1009 1013 10.1016/S0140-6736(97)11082-0 9546506 (Pubitemid 28154376)
38. Socioeconomic inequalities in morbidity and mortality in western Europe. Mackenbach JP, Kunst AE, Cavelaars AEJM, Groenhof F, Geurts JJM, Studygroup A, Gunning-Schepers L, Lancet 1997 349 1655 1659 10.1016/S0140-6736(96)07226-1 9186383 (Pubitemid 27234807)
39. Self-rated health among Hispanic vs non-Hispanic white adults: the San Luis Valley Health and Aging Study. Shetterly SM, Baxter J, Mason LD, Hamman RF, Am J Public Health 1996 86 12 1798 1801 10.2105/AJPH.86.12.1798 9003141
40. Self-rated health and mortality: short-and long-term associations in the Whitehall II study. Singh-Manoux A, Guéguen A, Martikainen P, Ferrie J, Marmot M, Shipley M, Psychosom Med 2007 69 2 138 143 10.1097/PSY. 0b013e318030483a 17289825 (Pubitemid 46667980)
41. Evaluating the quality of self-reports of hypertension and diabetes. Goldman N, Lin IF, Weinstein M, Lin YH, J Clin Epidemiol 2003 56 2 148 154 10.1016/S0895-4356(02)00580-2 12654409 (Pubitemid 36315941)
42. Ten dimensions of health and their relationships with overall selfreported health and survival in a predominately religiously active elderly population: the cache county memory study. Østbye T, Krause KM, Norton MC, Tschanz JA, Sanders L, Hayden K, Pieper C, WelshBohmer KA, J Am Geriatr Soc 2005 54 2 199 209
43. Social-cognitive and cognitive correlates of depression in children. Kaslow NJ, Rehm LP, Siegel AW, J Abnorm Child Psych 1984 12 4 605 620 10.1007/BF00916853 (Pubitemid 15203276)
44. Health Consequences of Familial Longevity Influence Among the Chinese Elderly. Zeng Y, Chen H, Shi X, Yin Z, Yang Z, Gu J, Blazer D, J Gerontol A Biol Sci Med Sci 2012 doi:10.1093/gerona/gls203.
45. IOM (Institute of Medicine NAoSC), Genes, behavior, and the social environment: Moving beyond the nature/nurture debate Washington, D.C: National Academia of Sciences 2006
46. Rothman KJ, Epidemiology: An Introduction New York: Oxford University Press, USA 2002
47. Interactions between life stress factors and carrying the APOE4 allele adversely impact self-reported health in old adults. Zeng Y, Hughes CL, Lewis MA, Li J, Zhang F, J Gerontol A Biol Sci Med Sci 2011 66 10 1054 1061 21768502
48. Muthén LK, Muthén BO, Mplus: Statistical Analysis with Latent Variables; User's Guide; [Version 6] Los Angeles, CA: Muthén & Muthén 2010 21838862
49. Aiken LS, West SG, Reno RR, Multiple regression: testing and interpreting interactions Newbury Park, CA: Sage Publications, Inc 1991
50. Analysis and evaluation of moderator effects in regression models: state of art, alternatives and empirical example. Helm R, Mark A, Rev Manag Sci 2012 6 4 307 332 10.1007/s11846-010-0057-y
51. Structural equation modeling of gene-environment interactions in coronary heart disease. Mi X, Eskridge KM, George V, Wang D, Ann Hum Genet 2011 75 2 255 265 21241273
52. Byrne B, Structural equation modeling with LISREL, PRELIS, and SIMPLIS: Basic concepts, applications, and programming Mahwah, NJ: Lawrence Erlbaum 1998
53. Asymptotic confidence intervals for indirect effects in structural equation models. Sobel ME, Sociol Methodology 1982 13 290 312
54. Total, direct, and indirect effects in structural equation models. Bollen KA, Sociol Methodology 1987 17 1 37 69
55. Confidence interval estimation of interaction. Hosmer DW, Lemeshow S, Epidemiology 1992 3 5 452 456 10.1097/00001648-199209000-00012 1391139
56. Beta-adrenoceptors on lymphocytes of patients with major depressive disorder. Carstens ME, Engelbrecht AH, Russell VA, Aalbers C, Gagiano CA, Chalton DO, Talijaard JJF, Psychiatr Res 1987 20 3 239 248 10.1016/0165-1781(87) 90084-9 (Pubitemid 17042403)
57. Decreased beta-adrenergic receptors in the leukocytes of depressed patients. Pandey GN, Janicak PG, Davis JM, Psychiatr Res 1987 22 4 265 273 10.1016/0165-1781(87)90105-3 (Pubitemid 18016501)
58. Epigenetic and mitochondrial mechanisms in aging and longevity: a report of a meeting of the longevity consortium, Napa, California, October 25-27, 2006. Kahn AJ, J Gerontol A Biol Sci Med Sci 2007 62 6 577 582 10.1093/gerona/62.6. 577 17595412 (Pubitemid 47300186)
59. McDonald JH, Handbook of biological statistics, Volume 2 Baltimore, MD: Sparky House Publishing 2009
60. Motulsky H, Intuitive biostatistics: a nonmathematical guide to statistical thinking Oxford: Oxford University Press 2010
61. Adjusting for multiple testing-when and how? Bender R, Lange S, J Clin Epidemiol 2001 54 4 343 349 10.1016/S0895-4356(00)00314-0 11297884 (Pubitemid 32303457)