Common genetic variants of the β2-adrenergic receptor affect its translational efficiency and are associated with human longevity

Aging Cell

Volumn 11, Issue 6, 2012, Pages 1094-1101

  Zhao, Ling ^a   Yang, Fan ^a   Xu, Ke ^a   Cao, Huiqing ^a   Zheng, Gu Yan ^a   Zhang, Yan ^a   Li, Jianxin ^a   Cui, Hanbin ^b   Chen, Xiaomin ^b   Zhu, Zhiming ^c   He, Hongbo ^d   Mo, Xianming ^e   Kennedy, Brian K ^e   Suh, Yousin ^f   Zeng, Yi ^a,g   Tian, Xiao Li ^a  

^a PEKING UNIVERSITY   (China)

^b NINGBO UNIVERSITY   (China)

^c THIRD MILITARY MEDICAL UNIVERSITY   (China)

^d SICHUAN UNIVERSITY   (China)

^e BUCK INSTITUTE FOR RESEARCH ON AGING   (United States)

^f ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^g DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

2 adrenergic receptor; Haplotype; Longevity; Single nucleotide polymorphism; Translational efficiency

Indexed keywords

ADENYLATE CYCLASE; ADENYLATE CYCLASE 5; ADENYLATE CYCLASE 6; BETA 1 ADRENERGIC RECEPTOR; BETA 2 ADRENERGIC RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE 1; UNCLASSIFIED DRUG;

ARTICLE; CHINESE; FEMALE; FOLLOW UP; GENE LINKAGE DISEQUILIBRIUM; GENETIC VARIABILITY; GENOTYPE; HAPLOTYPE; HEALTH SURVEY; HUMAN; LONGEVITY; MALE; PRIORITY JOURNAL; PROBABILITY; SIGNAL TRANSDUCTION; SINGLE NUCLEOTIDE POLYMORPHISM; STATISTICAL SIGNIFICANCE;

ADENYLATE CYCLASE; AGED, 80 AND OVER; AGING; ASIAN CONTINENTAL ANCESTRY GROUP; CASE-CONTROL STUDIES; FEMALE; FOLLOW-UP STUDIES; GENES, REPORTER; HAPLOTYPES; HEK293 CELLS; HUMANS; LINKAGE DISEQUILIBRIUM; LONGEVITY; LUCIFERASES, RENILLA; MALE; MITOGEN-ACTIVATED PROTEIN KINASE 1; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTEIN BIOSYNTHESIS; QUESTIONNAIRES; RECEPTORS, ADRENERGIC, BETA-1; RECEPTORS, ADRENERGIC, BETA-2; TRANSFECTION;

MUS;

EID: 84869158482     PISSN: 14749718     EISSN: 14749726     Source Type: Journal    
DOI: 10.1111/acel.12011     Document Type: Article

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