A novel plasmid and SonoVue formulation plus ultrasound sonication for effective gene delivery in nude mice

Life Sciences

Volumn 93, Issue 16, 2013, Pages 536-542

  Wang, Xin Lu ^a   Zhao, Xiao Yun ^b   Li, Shuo ^a   Jia, Chang Jun ^a   Jiang, Luo ^a   Shi, Tei Mei ^a   Ren, Wei Dong ^a  

^a CHINA MEDICAL UNIVERSITY   (China)

^b SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Gene therapy; Microbubbles; Ovarian neoplasms; Transfection; Ultrasound

Indexed keywords

COMPLEMENTARY DNA; MESSENGER RNA; PLASMID DNA; SONOVUE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CAPILLARY DENSITY; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; GENE TARGETING; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; MICROBUBBLE; MOUSE; NICK END LABELING; NONHUMAN; PLASMID; TUMOR XENOGRAFT; ULTRASOUND;

GENE THERAPY; MICROBUBBLES; OVARIAN NEOPLASMS; TRANSFECTION; ULTRASOUND;

ANIMALS; APOPTOSIS; FEMALE; GENE EXPRESSION; GENETIC VECTORS; MICE; OVARIAN NEOPLASMS; PHOSPHOLIPIDS; PLASMIDS; SIMPLEXVIRUS; SONICATION; SULFUR HEXAFLUORIDE; THYMIDINE KINASE; TRANSFECTION; TRANSPLANTATION, HETEROLOGOUS; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-2; XENOGRAFT MODEL ANTITUMOR ASSAYS;

MUS; MUS MUSCULUS; SIMPLEXVIRUS;

EID: 84884908914     PISSN: 00243205     EISSN: 18790631     Source Type: Journal    
DOI: 10.1016/j.lfs.2013.08.015     Document Type: Article

References (35)

1. T. Asahara, C. Bauters, L.P. Zheng, S. Takeshita, S. Bunting, and N. Ferrara Synergistic effect of vascular endothelial growth factor and basic fibroblast growth factor on angiogenesis in vivo Circulation 92 1995 II365 II371
2. R. Bekeredjian, S. Chen, P.A. Frenkel, P.A. Grayburn, and R.V. Shohet Ultrasound-targeted microbubble destruction can repeatedly direct highly specific plasmid expression to the heart Circulation 108 2003 1022 1026
3. R. Bianco, R. Rosa, V. Damiano, G. Daniele, T. Gelardi, and S. Garofalo Vascular endothelial growth factor receptor-1 contributes to resistance to anti-epidermal growth factor receptor drugs in human cancer cells Clin Cancer Res 14 2008 5069 5080
4. G. Coukos, and S.C. Rubin Gene therapy for ovarian cancer Oncology (Williston Park) 15 2001 1197 1204 [207; discussion 207-8]
5. J.M. Escoffre, K. Kaddur, M.P. Rols, and A. Bouakaz In vitro gene transfer by electrosonoporation Ultrasound Med Biol 36 2010 1746 1755
6. N. Ferrara Role of vascular endothelial growth factor in physiologic and pathologic angiogenesis: therapeutic implications Semin Oncol 29 2002 10 14
7. C. Fillat, M. Carrio, A. Cascante, and B. Sangro Suicide gene therapy mediated by the herpes simplex virus thymidine kinase gene/ganciclovir system: fifteen years of application Curr Gene Ther 3 2003 13 26
8. J. Folkman Angiogenesis in cancer, vascular, rheumatoid and other disease Nat Med 1 1995 27 31
9. S. Horie, Y. Watanabe, R. Chen, S. Mori, Y. Matsumura, and T. Kodama Development of localized gene delivery using a dual-intensity ultrasound system in the bladder Ultrasound Med Biol 36 2010 1867 1875
10. N.N.A. Howlader, M. Krapcho, N. Neyman, R. Aminou, S.F. Altekruse, and C.L. Kosary SEER cancer statistics review, 1975-2009 (Vintage 2009 Populations) 2012 National Cancer Institute Bethesda, MD [ http://seer.cancer.gov/csr/1975- 2009-pops09/, based on November 2011 SEER data submission, posted to the SEER web site, 2012]
11. A. Jemal, R. Siegel, J. Xu, and E. Ward Cancer statistics CA Cancer J Clin 60 2010 277 300
12. L.R. Jiao, R. Havlik, J. Nicholls, S.L. Jensen, and N.A. Habib Suicide gene therapy in liver tumors Methods Mol Med 90 2004 433 450
13. H.J. Kim, J.F. Greenleaf, R.R. Kinnick, J.T. Bronk, and M.E. Bolander Ultrasound-mediated transfection of mammalian cells Hum Gene Ther 7 1996 1339 1346
14. H.L. Li, X.Z. Zheng, H.P. Wang, F. Li, Y. Wu, and L.F. Du Ultrasound-targeted microbubble destruction enhances AAV-mediated gene transfection in human RPE cells in vitro and rat retina in vivo Gene Ther 16 2009 1146 1153
15. T. Maass, F.R. Thieringer, A. Mann, T. Longerich, P. Schirmacher, and D. Strand Liver specific overexpression of platelet-derived growth factor-B accelerates liver cancer development in chemically induced liver carcinogenesis Int J Cancer 128 2011 1259 1268
16. J.M. Markert, M.D. Medlock, S.D. Rabkin, G.Y. Gillespie, T. Todo, and W.D. Hunter Conditionally replicating herpes simplex virus mutant, G207 for the treatment of malignant glioma: results of a phase I trial Gene Ther 7 2000 867 874
17. M. Markman, J. Sehouli, C.F. Levenback, and D.S. Chi Epithelial ovarian cancer: focus on targeted therapy J Oncol 2010 2010 171425
18. S. Mehier-Humbert, T. Bettinger, F. Yan, and R.H. Guy Ultrasound-mediated gene delivery: kinetics of plasmid internalization and gene expression J Control Release 104 2005 203 211
19. B.D. Meijering, R.H. Henning, W.H. Van Gilst, I. Gavrilovic, A. Van Wamel, and L.E. Deelman Optimization of ultrasound and microbubbles targeted gene delivery to cultured primary endothelial cells J Drug Target 15 2007 664 671
20. J.A. Nagy, A.M. Dvorak, and H.F. Dvorak VEGF-A and the induction of pathological angiogenesis Annu Rev Pathol 2 2007 251 275
21. Y. Nasu, T. Saika, S. Ebara, N. Kusaka, H. Kaku, and F. Abarzua Suicide gene therapy with adenoviral delivery of HSV-tK gene for patients with local recurrence of prostate cancer after hormonal therapy Mol Ther 15 2007 834 840
22. Ky Ng, and Y. Liu Therapeutic ultrasound: its application in drug delivery Med Res Rev 22 2002 204 223
23. A.M. Nick, R.L. Stone, G. Armaiz-Pena, B. Ozpolat, I. Tekedereli, and W.S. Graybill Silencing of p130cas in ovarian carcinoma: a novel mechanism for tumor cell death J Natl Cancer Inst 103 2011 1596 1612
24. F. Nie, H.X. Xu, M.D. Lu, Y. Wang, and Q. Tang Anti-angiogenic gene therapy for hepatocellular carcinoma mediated by microbubble-enhanced ultrasound exposure: an in vivo experimental study J Drug Target 16 2008 389 395
25. J.R. Ohlfest, A.B. Freese, and D.A. Largaespada Nonviral vectors for cancer gene therapy: prospects for integrating vectors and combination therapies Curr Gene Ther 5 2005 629 641
26. L.C. Phillips, A.L. Klibanov, B.R. Wamhoff, and J.A. Hossack Targeted gene transfection from microbubbles into vascular smooth muscle cells using focused, ultrasound-mediated delivery Ultrasound Med Biol 36 2010 1470 1480
27. K. Podolska, A. Stachurska, K. Hajdukiewicz, and M. Małecki Gene therapy prospects - intranasal delivery of therapeutic genes Adv Clin Exp Med 21 4 2012 Jul-Aug 525 534
28. M. Presta, P. Dell'Era, S. Mitola, E. Moroni, R. Ronca, and M. Rusnati Fibroblast growth factor/fibroblast growth factor receptor system in angiogenesis Cytokine Growth Factor Rev 16 2005 159 178
29. A.A. Rahim, S.L. Taylor, N.L. Bush, G.R. ter Haar, J.C. Bamber, and C.D. Porter Spatial and acoustic pressure dependence of microbubble-mediated gene delivery targeted using focused ultrasound J Gene Med 8 2006 1347 1357
30. P.J. Stone, M.J. Goodheart, S.L. Rose, B.J. Smith, B.R. DeYoung, and R.E. Buller The influence of microvessel density on ovarian carcinogenesis Gynecol Oncol 90 2003 566 571
31. Q. Tang, X. He, H. Liao, L. He, Y. Wang, and D. Zhou Ultrasound microbubble contrast agent-mediated suicide gene transfection in the treatment of hepatic cancer Oncol lett 4 2012 970
32. E.C. Unger, T.P. McCreery, and R.H. Sweitzer Ultrasound enhances gene expression of liposomal transfection Invest Radiol 32 1997 723 727
33. Y. Wang, H.-X. Xu, M.-D. Lu, and Q. Tang Expression of thymidine kinase mediated by a novel non-viral delivery system under the control of vascular endothelial growth factor receptor 2 promoter selectively kills human umbilical vein endothelial cells World J Gastroenterol 14 2008 224
34. G.Z. Wang, J.H. Liu, S.Z. Lu, Y. Lu, C.J. Guo, and D.H. Zhao Ultrasonic destruction of albumin microbubbles enhances gene transfection and expression in cardiac myocytes Chin Med J (Engl) 124 2011 1395 1400
35. N. Weidner Current pathologic methods for measuring intratumoral microvessel density within breast carcinoma and other solid tumors Breast Cancer Res Treat 36 1995 169 180