Targeted gene transfection from microbubbles into vascular smooth muscle cells using focused, ultrasound-mediated delivery

Ultrasound in Medicine and Biology

Volumn 36, Issue 9, 2010, Pages 1470-1480

  Phillips, Linsey C ^a   Klibanov, Alexander L ^b   Wamhoff, Brian R ^b   Hossack, John A ^a  

^a University of Virginia   (United States)

^b UNIVERSITY OF VIRGINIA   (United States)

Author keywords

Contrast agents; Gene delivery; Sonoporation; Ultrasound

Indexed keywords

ACOUSTIC PRESSURES; CONTRAST AGENT; FOCUSED ULTRASOUND; GENE DELIVERY; GENE TRANSFECTION; IN-VITRO; MICRO-BUBBLE; MICROBUBBLES; PLASMID DNA; PULSE DURATIONS; PULSE REPETITION FREQUENCIES; SMOOTH MUSCLE CELLS; SONOPORATION; ULTRASOUND; VASCULAR SMOOTH MUSCLE CELLS;

BLOOD VESSEL PROSTHESES; CELLS; DNA; GENE TRANSFER; GENES; MICROBIOLOGY; MUSCLE; NUCLEIC ACIDS; ULTRASONICS;

ULTRASONIC TRANSMISSION;

CATION; DISTEAROYLPHOSPHATIDYLCHOLINE; ECHO CONTRAST MEDIUM; LIPID COATED MICROBUBBLE; MACROGOL; PERFLUBUTANE; PLASMID DNA; RED FLUORESCENT PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; FOCUSED ULTRASOUND; GENE TARGETING; GENETIC TRANSFECTION; IN VITRO STUDY; MICROBUBBLE; NONHUMAN; PRIORITY JOURNAL; RAT; REPORTER GENE; SMOOTH MUSCLE FIBER; SOUND PRESSURE; ULTRASOUND; VASCULAR SMOOTH MUSCLE;

ANIMALS; CELLS, CULTURED; DRUG DELIVERY SYSTEMS; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; MICROBUBBLES; MUSCLE, SMOOTH, VASCULAR; PLASMIDS; RATS;

EID: 77956014778     PISSN: 03015629     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ultrasmedbio.2010.06.010     Document Type: Article

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