Efficient new synthesis of N-arylbenzo[b]furo[3,2-d]pyrimidin-4-amines and their benzo[b]thieno[3,2-d]pyrimidin-4-amine analogues via a microwave-assisted Dimroth rearrangement

Journal of Heterocyclic Chemistry

Volumn 50, Issue 5, 2013, Pages 1187-1197

  Loidreau, Yvonnick ^a   Dubouilh Benard, Carole ^a   Marchand, Pascal ^b   Nourrisson, Marie Renée ^b   Duflos, Muriel ^b   Buquet, Catherine ^c   Corbière, Cécile ^c   Besson, Thierry ^a  

^a UNIVERSITÉ DE ROUEN   (France)

^b UNIVERSITÉ DE NANTES   (France)

^c UNIVERSITÉ DE ROUEN   (France)

Author keywords

[No Author keywords available]

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; 3 (4 NITROPHENYL)BENZO[B]FURO[3,2 D]PYRIMIDIN 4(3H) IMINE; 3 AMINO 2 CYANOBENZO[B]FURANE; 3 AMINO 2 CYANOBENZO[B]THIOPHENE; 4 (BENZO[4,5]THIENO[3,2 D]PYRIMIDIN 4 YLAMINO) 2 NITROPHENOL; 4 (BENZOFURO[3,2 D]PYRIMIDIN 4 YLAMINO) 2 NITROPHENOL; BENZO[B]FURO[3,2 D]PYRIMIDIN 4 AMINE; BENZO[B]THIENO [3,2 D]PYRIMIDIN 4 AMINE; N (2,3 DIHYDROBENZO[B][1,4]DIOXIN 6 YL)BENZO[4,5]THIENO[3,2 D]PYRIMIDIN 4 AMINE; N (2,3 DIHYDROBENZO[B][1,4]DIOXIN 6 YL)BENZOFURO[3,2 D]PYRIMIDIN 4 AMINE; N (3 CHLORO 4 FLUOROPHENYL)BENZO[B]FURO[3,2 D]PYRIMIDIN 4 AMINE; N (3 CHLORO 4 FLUOROPHENYL)BENZO[B]THIENO[3,2 D]PYRIMIDIN 4 AMINE; N (3,4 DIMETHOXYPHENYL)BENZO[B]FURO[3,2 D]PYRIMIDIN 4 AMINE; N (3,4 DIMETHOXYPHENYL)BENZO[B]THIENO[3,2 D]PYRIMIDIN 4 AMINE; N (3,4,5 TRIMETHOXYPHENYL)BENZO[B]FURO[3,2 D]PYRIMIDIN 4 AMINE; N (3,4,5 TRIMETHOXYPHENYL)BENZO[B]THIENO[3,2 D]PYRIMIDIN 4 AMINE; N (3,5 DIMETHOXYPHENYL)BENZO[B]FURO[3,2 D]PYRIMIDIN 4 AMINE; N (3,5 DIMETHOXYPHENYL)BENZO[B]THIENO[3,2 D]PYRIMIDIN 4 AMINE; N (4 BROMO 2 FLUOROPHENYL)BENZO[B]FURO[3,2 D]PYRIMIDIN 4 AMINE; N (4 BROMO 2 FLUOROPHENYL)BENZO[B]THIENO[3,2 D]PYRIMIDIN 4 AMINE; N (4 METHOXYPHENYL)BENZO[B]FURO[3,2 D]PYRIMIDIN 4 AMINE; N (4 METHOXYPHENYL)BENZO[B]THIENO[3,2 D]PYRIMIDIN 4 AMINE; N (BENZO[D][1,3]DIOXOL 5 YL)BENZO[4,5]THIENO[3,2 D]PYRIMIDIN 4 AMINE; N (BENZO[D][1,3]DIOXOL 5 YL)BENZOFURO[3,2 D]PYRIMIDIN 4 AMINE; N ARYLBENZO[B]FURO[3,2 D]PYRIMIDIN 4 AMINE; N PHENYLBENZO[B]FURO[3,2 D]PYRIMIDIN 4 AMINE; N PHENYLBENZO[B]THIENO[3,2 D]PYRIMIDIN 4 AMINE; N' (2 CYANOBENZO[B]FURAN 3 YL) N,N DIMETHYLFORMIMIDAMIDE; N' (2 CYANOBENZO[B]THIOPHEN 3 YL) N,N DIMETHYLFORMIMIDAMIDE; PYRIMIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIPROLIFERATIVE ACTIVITY; ARTICLE; ATMOSPHERIC PRESSURE; CELL PROLIFERATION; CELL STRAIN CACO 2; CONTROLLED STUDY; DRUG SYNTHESIS; GROWTH INHIBITION; HYDROLYSIS; IN VITRO STUDY; ISOMER; MICROWAVE ASSISTED DIMROTH REARRANGEMENT; MICROWAVE COOKING; MICROWAVE IRRADIATION; MICROWAVE RADIATION; NUCLEOPHILICITY; REACTION ANALYSIS; REACTION TIME; STEREOSPECIFICITY; THIN LAYER CHROMATOGRAPHY;

EID: 84884902800     PISSN: 0022152X     EISSN: 19435193     Source Type: Journal    
DOI: 10.1002/jhet.1716     Document Type: Article

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