Differential sensitivities of the MRP gene family and γ-glutamylcysteine synthetase to prooxidants in human colorectal carcinoma cell lines with different p53 status

Biochemical Pharmacology

Volumn 61, Issue 5, 2001, Pages 555-563

  Lin Lee, Yen Chiu ^a   Tatebe, Shigeru ^a   Savaraj, Niramol ^b   Ishikawa, Toshihisa ^c   Tien Kuo, M ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c TOKYO INSTITUTE OF TECHNOLOGY   (Japan)

Author keywords

Antioxidants; Chemotherapy; Drug transporter; Gene regulation; Multidrug resistance protein

Indexed keywords

GLUTAMATE CYSTEINE LIGASE; GLUTATHIONE; MESSENGER RNA; PROTEIN P53; PYRROLIDINE DITHIOCARBAMATE; TERT BUTYLHYDROQUINONE;

ALLELE; ARTICLE; COLORECTAL CARCINOMA; CONTROLLED STUDY; ENZYME INDUCTION; GENE EXPRESSION; GENE INDUCTION; HUMAN; HUMAN CELL; MULTIGENE FAMILY; MUTATION; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ATP-BINDING CASSETTE TRANSPORTERS; COLORECTAL NEOPLASMS; ENZYME INDUCTION; GLUTAMATE-CYSTEINE LIGASE; GLUTATHIONE; HUMANS; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; OXIDANTS; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEIN P53;

EID: 0035282671     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(00)00592-X     Document Type: Article

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