Liver Ischemic Preconditioning (IPC) Improves Intestinal Microbiota Following Liver Transplantation in Rats through 16s rDNA-Based Analysis of Microbial Structure Shift

PLoS ONE

Volumn 8, Issue 10, 2013, Pages

  Ren, Zhigang ^a,b   Cui, Guangying ^c   Lu, Haifeng ^c   Chen, Xinhua ^a,b   Jiang, Jianwen ^a,b   Liu, Hui ^b   He, Yong ^a,b   Ding, Songming ^a,b   Hu, Zhenhua ^a,b   Wang, Weilin ^a,b   Zheng, Shusen ^a,b  

^a ZHEJIANG UNIVERSITY   (China)

^b ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

^c ZHEJIANG UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; DNA 16S; ENDOTOXIN; IMMUNOGLOBULIN A; TUMOR NECROSIS FACTOR ALPHA;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BACTERIAL TRANSLOCATION; BACTEROIDETES; BIFIDOBACTERIUM; CLOSTRIDIUM; CLUSTER ANALYSIS; CONTROLLED STUDY; DENATURING GRADIENT GEL ELECTROPHORESIS; FECES MICROFLORA; INTESTINE FLORA; INTESTINE MUCOSA; ISCHEMIC PRECONDITIONING; LIVER ISCHEMIC PRECONDITIONING; LIVER TRANSPLANTATION; MICROBIAL DIVERSITY; NONHUMAN; NUCLEOTIDE SEQUENCE; PHYLOGENETIC TREE; POLYMERASE CHAIN REACTION; POSITIVE FEEDBACK; QUANTITATIVE ANALYSIS; RAT; SEQUENCE ANALYSIS; SPECIES RICHNESS; ULTRASTRUCTURE;

ANIMALS; CLUSTER ANALYSIS; DNA, RIBOSOMAL; FECES; INTESTINES; ISCHEMIC PRECONDITIONING; LIVER; LIVER TRANSPLANTATION; MICROBIOTA; PHYLOGENY; RATS;

EID: 84884830898     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0075950     Document Type: Article

References (35)

1. Åberg F, Isoniemi H, Höckerstedt K, (2011) Long-term results of liver transplantation. Scand J Surg 100: 14-21. PubMed: 21482501.
2. Hübscher SG, (2011) What is the long-term outcome of the liver allograft? J Hepatol 55: 702-717. doi:10.1016/j.jhep.2011.03.005. PubMed: 21426919.
3. Wiesner RH, Menon KV, (2001) Late hepatic allograft dysfunction. Liver Transpl 7: S60-S73. doi:10.1053/jlts.2001.29094. PubMed: 11689778.
4. Glanemann M, Langrehr J, Kaisers U, Schenk R, Müller A, et al. (2001) Postoperative tracheal extubation after orthotopic liver transplantation. Acta Anaesthesiol Scand 45: 333-339. doi:10.1034/j.1399-6576.2001.045003333.x. PubMed: 11207470.
5. Eckburg PB, Bik EM, Bernstein CN, Purdom E, Dethlefsen L, et al. (2005) Diversity of the human intestinal microbial flora. Science 308: 1635-1638. doi:10.1126/science.1110591. PubMed: 15831718.
6. Nenci A, Becker C, Wullaert A, Gareus R, van Loo G, et al. (2007) Epithelial NEMO links innate immunity to chronic intestinal inflammation. Nature 446: 557-561. doi:10.1038/nature05698. PubMed: 17361131.
7. Cani PD, Delzenne NM, (2009) The role of the gut microbiota in energy metabolism and metabolic disease. Curr Pharm Des 15: 1546-1558. doi:10.2174/138161209788168164. PubMed: 19442172.
8. Gill SR, Pop M, Deboy RT, Eckburg PB, Turnbaugh PJ, et al. (2006) Metagenomic analysis of the human distal gut microbiome. Science 312: 1355-1359. doi:10.1126/science.1124234. PubMed: 16741115.
9. Bäckhed F, Ley RE, Sonnenburg JL, Peterson DA, Gordon JI, (2005) Host-bacterial mutualism in the human intestine. Science 307: 1915-1920. doi:10.1126/science.1104816. PubMed: 15790844.
10. Hooper LV, Midtvedt T, Gordon JI, (2002) How host-microbial interactions shape the nutrient environment of the mammalian intestine. Annu Rev Nutr 22: 283-307. doi:10.1146/annurev.nutr.22.011602.092259. PubMed: 12055347.
11. Wang F, Li Q, Wang C, Tang C, Li J, (2012) Dynamic alteration of the colonic microbiota in intestinal ischemia-reperfusion injury. PLOS ONE 7: e42027. doi:10.1371/journal.pone.0042027. PubMed: 22848694.
12. Li Q, Zhang Q, Wang C, Tang C, Zhang Y, et al. (2011) Fish oil enhances recovery of intestinal microbiota and epithelial integrity in chronic rejection of intestinal transplant. PLOS ONE 6: e20460. doi:10.1371/journal.pone.0020460. PubMed: 21698145.
13. Xing HC, Li LJ, Xu KJ, Shen T, Chen YB, et al. (2006) Protective role of supplement with foreign Bifidobacterium and Lactobacillus in experimental hepatic ischemia-reperfusion injury. J Gastroenterol Hepatol 21: 647-656. doi:10.1111/j.1440-1746.2006.04306.x. PubMed: 16677148.
14. Chassaing B, Etienne-Mesmin L, Gewirtz AT, (2013) Microbiota-liver axis in hepatic disease. Hepatology. PubMed: 23703735.
15. Kim YW, Ogilvy CS, Pricola K, Reavey-Cantwell JF, Kelman CR, et al. (2012) 130 Evidence for an ischemic preconditioning effect on cerebral vasospasm in patients with aneurysmal subarachnoid hemorrhage. Neurosurgery 71: E553. doi:10.1227/01.neu.0000417722.33956.86.
16. Kelsey R, (2012) Acute kidney injury: Ischaemic preconditioning for preventing contrast-induced AKI. Nat Rev Nephrol.
17. Er F, Nia AM, Dopp H, Hellmich M, Dahlem KM, et al. (2012) Ischemic Preconditioning for Prevention of Contrast Medium-Induced Nephropathy: Randomized Pilot RenPro Trial (Renal Protection Trial). Circulation 126: 296-303. doi:10.1161/CIR.0b013e31827735bc. PubMed: 22735306.
18. Murry CE, Jennings RB, Reimer KA, (1986) Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardium. Circulation 74: 1124-1136. doi:10.1161/01.CIR.74.5.1124. PubMed: 3769170.
19. Cai ZP, Parajuli N, Zheng X, Becker L, (2012) Remote ischemic preconditioning confers late protection against myocardial ischemia-reperfusion injury in mice by upregulating interleukin-10. Basic Res Cardiol 107: 277. doi:10.1007/s00395-012-0277-1. PubMed: 22752341.
20. Kamada N, Calne RY, (1983) A surgical experience with five hundred thirty liver transplants in the rat. Surgery 93: 64-69. PubMed: 6336859.
21. Ren ZG, Liu H, Jiang JW, Jiang L, Chen H, et al. (2011) Protective effect of probiotics on intestinal barrier function in malnourished rats after liver transplantation. Hepatobiliary Pancreat Dis Int 10: 489-496. doi:10.1016/S1499-3872(11)60083-0. PubMed: 21947722.
22. Suzuki S, Toledo-Pereyra LH, Rodriguez FJ, Cejalvo D, (1993) Neutrophil infiltration as an important factor in liver ischemia and reperfusion injury. Modulating effects of FK506 and cyclosporine. Transplantation 55: 1265-1272. doi:10.1097/00007890-199306000-00011. PubMed: 7685932.
23. Shen XD, Ke B, Zhai Y, Gao F, Anselmo D, et al. (2003) Stat4 and Stat6 signaling in hepatic ischemia/reperfusion injury in mice: HO-1 dependence of Stat4 disruption-mediated cytoprotection. Hepatology 37: 296-303. doi:10.1053/jhep.2003.50066. PubMed: 12540779.
24. Deschênes M, Belle SH, Krom RA, Zetterman RK, Lake JR, (1998) Early allograft dysfunction after liver transplantation: a definition and predictors of outcome. National Institute of Diabetes and Digestive and Kidney Diseases Liver Transplantation Database. Transplantation 66: 302-310. doi:10.1097/00007890-199808150-00005. PubMed: 9721797.
25. Jaeschke H, (1996) Preservation injury: mechanisms, prevention and consequences. J Hepatol 25: 774-780. doi:10.1016/S0168-8278(96)80253-4. PubMed: 8938560.
26. Lloris-Carsí JM, Cejalvo D, Toledo-Pereyra LH, Calvo MA, Suzuki S, (1993) Preconditioning: effect upon lesion modulation in warm liver ischemia. Transplant Proc 25: 3303-3304. PubMed: 8266552.
27. Clavien PA, Yadav S, Sindram D, Bentley RC, (2000) Protective effects of ischemic preconditioning for liver resection performed under inflow occlusion in humans. Ann Surg 232: 155-162. doi:10.1097/00000658-200008000-00001. PubMed: 10903590.
28. Petrowsky H, McCormack L, Trujillo M, Selzner M, Jochum W, et al. (2006) A prospective, randomized, controlled trial comparing intermittent portal triad clamping versus ischemic preconditioning with continuous clamping for major liver resection. Ann Surg 244: 921-930; discussion: 17122617.
29. Peralta C, Hotter G, Closa D, Gelpí E, Bulbena O, et al. (1997) Protective effect of preconditioning on the injury associated to hepatic ischemia-reperfusion in the rat: role of nitric oxide and adenosine. Hepatology 25: 934-937. doi:10.1002/hep.510250424. PubMed: 9096600.
30. Chen Y, Yang F, Lu H, Wang B, Lei D, et al. (2011) Characterization of fecal microbial communities in patients with liver cirrhosis. Hepatology 54: 562-572. doi:10.1002/hep.24423. PubMed: 21574172.
31. Dapito DH, Mencin A, Gwak GY, Pradere JP, Jang MK, et al. (2012) Promotion of hepatocellular carcinoma by the intestinal microbiota and TLR4. Cancer Cell 21: 504-516. doi:10.1016/j.ccr.2012.02.007. PubMed: 22516259.
32. Yoshimoto S, Loo TM, Atarashi K, Kanda H, Sato S, et al. (2013) Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome. Nature 499: 97-101. doi:10.1038/nature12347. PubMed: 23803760.
33. Bass NM, Mullen KD, Sanyal A, Poordad F, Neff G, et al. (2010) Rifaximin treatment in hepatic encephalopathy. N Engl J Med 362: 1071-1081. doi:10.1056/NEJMoa0907893. PubMed: 20335583.
34. Tapuria N, Kumar Y, Habib MM, Abu Amara M, Seifalian AM, et al. (2008) Remote ischemic preconditioning: a novel protective method from ischemia reperfusion injury--a review. J Surg Res 150: 304-330. doi:10.1016/j.jss.2007.12.747. PubMed: 19040966.
35. Oh PL, Martínez I, Sun Y, Walter J, Peterson DA, et al. (2012) Characterization of the ileal microbiota in rejecting and nonrejecting recipients of small bowel transplants. Am J Transplant 12: 753-762. doi:10.1111/j.1600-6143.2011.03860.x. PubMed: 22152019.