Small Angle X-Ray Scattering Studies of Mitochondrial Glutaminase C Reveal Extended Flexible Regions, and Link Oligomeric State with Enzyme Activity

PLoS ONE

Volumn 8, Issue 9, 2013, Pages

  Møller, Magda ^a   Nielsen, Søren S ^a,b   Ramachandran, Sekar ^b   Li, Yuxing ^b   Tria, Giancarlo ^c,d   Streicher, Werner ^e   Petoukhov, Maxim V ^c   Cerione, Richard A ^b   Gillilan, Richard E ^b   Vestergaard, Bente ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b Department of Obstetrics Gynecology   (United States)

^c EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

^d UNIVERSITY OF HAMBURG   (Germany)

^e University of Copenhagen   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

GLUTAMINASE; MITOCHONDRIAL GLUTAMINASE C; PHOSPHATE; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONCENTRATION (PARAMETERS); ENZYME ACTIVITY; ENZYME PURIFICATION; MICROFLUIDICS; MOUSE; NONHUMAN; OLIGOMERIZATION; PROTEIN EXPRESSION; X RAY CRYSTALLOGRAPHY;

AREA UNDER CURVE; GLUTAMINASE; HUMANS; MICROFLUIDICS; MITOCHONDRIAL PROTEINS; MODELS, MOLECULAR; OLIGONUCLEOTIDES; PROTEIN CONFORMATION; SCATTERING, SMALL ANGLE;

EID: 84884805102     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0074783     Document Type: Article

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