-
1
-
-
77955273537
-
-
Lyon, France: International Agency for Research on Cancer; Available from: Accessed April 22, 2013
-
Ferlay J, Shin HR, Bray F, Forman D, Mathers C, Parkin DM. GLOBOCAN 2008 v2.0, Cancer Incidence and Mortality Worldwide: IARC CancerBase No 10 [homepage on the Internet]. Lyon, France: International Agency for Research on Cancer; 2010. Available from: http://globocan.iarc.fr. Accessed April 22, 2013.
-
(2010)
GLOBOCAN 2008 v2.0, Cancer Incidence and Mortality Worldwide: IARC CancerBase No 10 [homepage on the Internet]
-
-
Ferlay, J.1
Shin, H.R.2
Bray, F.3
Forman, D.4
Mathers, C.5
Parkin, D.M.6
-
2
-
-
84872967522
-
Cancer statistics, 2013
-
Siegel R, Naishadham D, Jemal A. Cancer statistics, 2013. CA Cancer J Clin. 2013;63(1):11-30.
-
(2013)
CA Cancer J Clin.
, vol.63
, Issue.1
, pp. 11-30
-
-
Siegel, R.1
Naishadham, D.2
Jemal, A.3
-
3
-
-
79961139784
-
Management strategies for recurrent platinum-resistant ovarian cancer
-
Naumann RW, Coleman RL. Management strategies for recurrent platinum-resistant ovarian cancer. Drugs. 2011;71(11):1397-1412.
-
(2011)
Drugs.
, vol.71
, Issue.11
, pp. 1397-1412
-
-
Naumann, R.W.1
Coleman, R.L.2
-
4
-
-
0024327106
-
Taxol: A unique antineoplastic agent with significant activity in advanced ovarian epithelial neoplasms
-
McGuire WP, Rowinsky EK, Rosenshein NB, et al. Taxol: a unique antineoplastic agent with significant activity in advanced ovarian epithelial neoplasms. Ann Int Med. 1989;111(4):273-279.
-
(1989)
Ann Int Med.
, vol.111
, Issue.4
, pp. 273-279
-
-
McGuire, W.P.1
Rowinsky, E.K.2
Rosenshein, N.B.3
-
5
-
-
0028153230
-
Phase II trial of paclitaxel in patients with progressive ovarian carcinoma after platinum-based chemotherapy: A Gynecologic Oncology Group study
-
Thigpen JT, Blessing JA, Ball H, Hummel SJ, Barrett RJ. Phase II trial of paclitaxel in patients with progressive ovarian carcinoma after platinum-based chemotherapy: a Gynecologic Oncology Group study. J Clin Oncol. 1994;12(9):1748-1753.
-
(1994)
J Clin Oncol.
, vol.12
, Issue.9
, pp. 1748-1753
-
-
Thigpen, J.T.1
Blessing, J.A.2
Ball, H.3
Hummel, S.J.4
Barrett, R.J.5
-
7
-
-
33646562149
-
Phase II trial of weekly paclitaxel (80 mg/m2) in platinum and paclitaxel-resistant ovarian and primary peritoneal cancers: A Gynecologic Oncology Group study
-
Gynecologic Oncology Group
-
Gynecologic Oncology Group, Markman M, Blessing J, et al. Phase II trial of weekly paclitaxel (80 mg/m2) in platinum and paclitaxel-resistant ovarian and primary peritoneal cancers: a Gynecologic Oncology Group study. Gynecol Oncol. 2006;101(3):436-440.
-
(2006)
Gynecol Oncol.
, vol.101
, Issue.3
, pp. 436-440
-
-
Markman, M.1
Blessing, J.2
-
8
-
-
77957564567
-
Weekly paclitaxel in the treatment of recurrent ovarian cancer
-
Baird RD, Tan DS, Kaye SB. Weekly paclitaxel in the treatment of recurrent ovarian cancer. Nat Rev Clin Oncol. 2010;7(10):575-582.
-
(2010)
Nat Rev Clin Oncol.
, vol.7
, Issue.10
, pp. 575-582
-
-
Baird, R.D.1
Tan, D.S.2
Kaye, S.B.3
-
9
-
-
0036407202
-
Randomized trial of single-agent paclitaxel given weekly versus every three weeks and with peroral versus intravenous steroid premedication to patients with ovarian cancer previously treated with platinum
-
Rosenberg P, Andersson H, Boman K, et al. Randomized trial of single-agent paclitaxel given weekly versus every three weeks and with peroral versus intravenous steroid premedication to patients with ovarian cancer previously treated with platinum. Acta Oncol. 2002;41(5):418-424.
-
(2002)
Acta Oncol.
, vol.41
, Issue.5
, pp. 418-424
-
-
Rosenberg, P.1
Andersson, H.2
Boman, K.3
-
10
-
-
0027999966
-
European-Canadian randomized trial of paclitaxel in relapsed ovarian cancer: High-dose versus low-dose and long versus short infusion
-
Eisenhauer EA, ten Bokkel Huinink WW, et al. European-Canadian randomized trial of paclitaxel in relapsed ovarian cancer: high-dose versus low-dose and long versus short infusion. J Clin Oncol. 1994;12(12):2654-2666.
-
(1994)
J Clin Oncol.
, vol.12
, Issue.12
, pp. 2654-2666
-
-
Eisenhauer, E.A.1
ten Bokkel Huinink, W.W.2
-
11
-
-
84856331988
-
Weekly paclitaxel as a single agent or in combination with carboplatin or weekly topotecan in patients with resistant ovarian cancer: The CARTAXHY randomized phase II trial from Groupe d'Investigateurs Nationaux pour l'Etude des Cancers Ovariens (GINECO)
-
GINECO group France
-
Lortholary A, Largillier R, Weber B, et al; GINECO group France. Weekly paclitaxel as a single agent or in combination with carboplatin or weekly topotecan in patients with resistant ovarian cancer: the CARTAXHY randomized phase II trial from Groupe d'Investigateurs Nationaux pour l'Etude des Cancers Ovariens (GINECO). Ann Oncol. 2012;23(2):346-352.
-
(2012)
Ann Oncol.
, vol.23
, Issue.2
, pp. 346-352
-
-
Lortholary, A.1
Largillier, R.2
Weber, B.3
-
12
-
-
0030900145
-
Topotecan versus paclitaxel for the treatment of recurrent epithelial ovarian cancer
-
ten Bokkel Huinink W, Gore M, Carmichael J, et al. Topotecan versus paclitaxel for the treatment of recurrent epithelial ovarian cancer. J Clin Oncol. 1997;15(6):2183-2193.
-
(1997)
J Clin Oncol.
, vol.15
, Issue.6
, pp. 2183-2193
-
-
ten Bokkel Huinink, W.1
Gore, M.2
Carmichael, J.3
-
13
-
-
1642579679
-
Topotecan dosing guidelines in ovarian cancer: Reduction and management of hematologic toxicity
-
Armstrong DK. Topotecan dosing guidelines in ovarian cancer: reduction and management of hematologic toxicity. Oncologist. 2004;9(1):33-42.
-
(2004)
Oncologist.
, vol.9
, Issue.1
, pp. 33-42
-
-
Armstrong, D.K.1
-
14
-
-
0031781459
-
Randomized phase ll study of two schedules of topotecan in previously treated patients with ovarian cancer: A National Cancer Institute of Canada Clinical Trials Group study
-
Hoskins P, Eisenhauer E, Beare S, et al. Randomized phase ll study of two schedules of topotecan in previously treated patients with ovarian cancer: a National Cancer Institute of Canada Clinical Trials Group study. J Clin Oncol. 1998;16(6):2233-2237.
-
(1998)
J Clin Oncol.
, vol.16
, Issue.6
, pp. 2233-2237
-
-
Hoskins, P.1
Eisenhauer, E.2
Beare, S.3
-
15
-
-
0033770154
-
Phase 2 evaluation of topotecan administered on a 3-day schedule in the treatment of platinum-and paclitaxel-refractory ovarian cancer
-
Markman M, Kennedy A, Webster K, Kulp B, Peterson G, Belinson J. Phase 2 evaluation of topotecan administered on a 3-day schedule in the treatment of platinum-and paclitaxel-refractory ovarian cancer. Gynecol Oncol. 2000;79(1):116-119.
-
(2000)
Gynecol Oncol.
, vol.79
, Issue.1
, pp. 116-119
-
-
Markman, M.1
Kennedy, A.2
Webster, K.3
Kulp, B.4
Peterson, G.5
Belinson, J.6
-
16
-
-
0031055830
-
Phase II study of liposomal doxorubicin in refractory ovarian cancer: Antitumor activity and toxicity modification by liposomal encapsulation
-
Muggia FM, Hainsworth JD, Jeffers S, et al. Phase II study of liposomal doxorubicin in refractory ovarian cancer: antitumor activity and toxicity modification by liposomal encapsulation. J Clin Oncol. 1997;15(3): 987-993.
-
(1997)
J Clin Oncol.
, vol.15
, Issue.3
, pp. 987-993
-
-
Muggia, F.M.1
Hainsworth, J.D.2
Jeffers, S.3
-
17
-
-
0033850066
-
Phase II study of liposomal doxorubicin in platinum-and paclitaxel-refractory epithelial ovarian cancer
-
Gordon AN, Granai CO, Rose PG, et al. Phase II study of liposomal doxorubicin in platinum-and paclitaxel-refractory epithelial ovarian cancer. J Clin Oncol. 2000;18(17):3093-3100.
-
(2000)
J Clin Oncol.
, vol.18
, Issue.17
, pp. 3093-3100
-
-
Gordon, A.N.1
Granai, C.O.2
Rose, P.G.3
-
18
-
-
4644225190
-
Long-term survival advantage for woman treated with pegylated liposomal doxorubicin compared with topotecan in a phase 3 randomized study of recurrent and refractory epithelial ovarian cancer
-
Doxil Study 30-49 Investigators
-
Gordon AN, Tonda M, Sun S, Rackoff W; Doxil Study 30-49 Investigators. Long-term survival advantage for woman treated with pegylated liposomal doxorubicin compared with topotecan in a phase 3 randomized study of recurrent and refractory epithelial ovarian cancer. Gynecol Oncol. 2004;95(1):1-8.
-
(2004)
Gynecol Oncol.
, vol.95
, Issue.1
, pp. 1-8
-
-
Gordon, A.N.1
Tonda, M.2
Sun, S.3
Rackoff, W.4
-
19
-
-
0035879099
-
Recurrent epithelial ovarian carcinoma: A randomized phase III study of pegylated liposomal doxorubicin versus topotecan
-
Gordon AN, Fleagle JT, Guthrie D, Parkin DE, Gore ME, Lacave AJ. Recurrent epithelial ovarian carcinoma: a randomized phase III study of pegylated liposomal doxorubicin versus topotecan. J Clin Oncol. 2001;19(14):3312-3322.
-
(2001)
J Clin Oncol.
, vol.19
, Issue.14
, pp. 3312-3322
-
-
Gordon, A.N.1
Fleagle, J.T.2
Guthrie, D.3
Parkin, D.E.4
Gore, M.E.5
Lacave, A.J.6
-
20
-
-
34447570846
-
Randomized phase III trial of gemcitabine compared with pegylated liposomal doxorubicin in patients with platinum-resistant ovarian cancer
-
Mutch DG, Orlando M, Goss T, et al. Randomized phase III trial of gemcitabine compared with pegylated liposomal doxorubicin in patients with platinum-resistant ovarian cancer. J Clin Oncol. 2007;25(19): 2811-2818.
-
(2007)
J Clin Oncol.
, vol.25
, Issue.19
, pp. 2811-2818
-
-
Mutch, D.G.1
Orlando, M.2
Goss, T.3
-
21
-
-
39749113438
-
Phase III trial of gemcitabine compared with pegylated liposomal doxorubicin in progressive or recurrent ovarian cancer
-
Ferrandina G, Ludovisi M, Lorusso D, et al. Phase III trial of gemcitabine compared with pegylated liposomal doxorubicin in progressive or recurrent ovarian cancer. J Clin Oncol. 2008;26(6):890-896.
-
(2008)
J Clin Oncol.
, vol.26
, Issue.6
, pp. 890-896
-
-
Ferrandina, G.1
Ludovisi, M.2
Lorusso, D.3
-
22
-
-
0029863194
-
Design, synthesis, and evaluation of latent alkylating agents activated by glutathione S-transferase
-
Satyam A, Hocker MD, Kane-Maguire KA, Morgan AS, Villar HO, Lyttle MH. Design, synthesis, and evaluation of latent alkylating agents activated by glutathione S-transferase. J Med Chem. 1996;39(8): 1736-1747.
-
(1996)
J Med Chem.
, vol.39
, Issue.8
, pp. 1736-1747
-
-
Satyam, A.1
Hocker, M.D.2
Kane-Maguire, K.A.3
Morgan, A.S.4
Villar, H.O.5
Lyttle, M.H.6
-
23
-
-
0028356487
-
Glutathione-S-transferase activates novel alkylating agents
-
Lyttle MH, Satyam A, Hocker MD, et al. Glutathione-S-transferase activates novel alkylating agents. J Med Chem. 1994;37(10):1501-1507.
-
(1994)
J Med Chem.
, vol.37
, Issue.10
, pp. 1501-1507
-
-
Lyttle, M.H.1
Satyam, A.2
Hocker, M.D.3
-
24
-
-
77955713764
-
Glutathione transferases as mediators of signaling pathways involved in cell proliferation and cell death
-
Laborde E. Glutathione transferases as mediators of signaling pathways involved in cell proliferation and cell death. Cell Death Differ. 2010;17(9):1373-1380.
-
(2010)
Cell Death Differ.
, vol.17
, Issue.9
, pp. 1373-1380
-
-
Laborde, E.1
-
25
-
-
68749089764
-
Phase 3 randomised study of canfosfamide (Telcyta®, TLK286) versus pegylated liposomal doxorubicin or topotecan as third-line therapy in patients with platinum-refractory or-resistant ovarian cancer
-
ASSIST-1 Study Group
-
Vergote I, Finkler N, del Campo J, et al; ASSIST-1 Study Group. Phase 3 randomised study of canfosfamide (Telcyta®, TLK286) versus pegylated liposomal doxorubicin or topotecan as third-line therapy in patients with platinum-refractory or-resistant ovarian cancer. Eur J Cancer. 2009;45:2324-2332.
-
(2009)
Eur J Cancer.
, vol.45
, pp. 2324-2332
-
-
Vergote, I.1
Finkler, N.2
del Campo, J.3
-
26
-
-
77956807267
-
Randomized phase III study of canfosfamide in combination with pegylated liposomal doxorubicin compared with pegylated liposomal doxorubicin alone in platinum-resistant ovarian cancer
-
Vergote I, Finkler NJ, Hall JB, et al. Randomized phase III study of canfosfamide in combination with pegylated liposomal doxorubicin compared with pegylated liposomal doxorubicin alone in platinum-resistant ovarian cancer. Int J Gynecol Cancer. 2010;20(5): 772-780.
-
(2010)
Int J Gynecol Cancer.
, vol.20
, Issue.5
, pp. 772-780
-
-
Vergote, I.1
Finkler, N.J.2
Hall, J.B.3
-
27
-
-
73949121440
-
Phase II clinical trial of ixabepilone in patients with recurrent or persistent platinum-and taxane-resistant ovarian or primary peritoneal cancer: A gynecologic oncology group study
-
De Geest K, Blessing JA, Morris RT, et al. Phase II clinical trial of ixabepilone in patients with recurrent or persistent platinum-and taxane-resistant ovarian or primary peritoneal cancer: a gynecologic oncology group study. J Clin Oncol. 2010;28(1):149-153.
-
(2010)
J Clin Oncol.
, vol.28
, Issue.1
, pp. 149-153
-
-
De Geest, K.1
Blessing, J.A.2
Morris, R.T.3
-
28
-
-
84869109927
-
Randomized, open-label, phase III study comparing patupilone (EPO906) with pegylated liposomal doxorubicin in platinum-refractory or-resistant patients with recurrent epithelial ovarian, primary fallopian tube, or primary peritoneal cancer
-
Colombo N, Kutarska E, Dimopoulos M, et al. Randomized, open-label, phase III study comparing patupilone (EPO906) with pegylated liposomal doxorubicin in platinum-refractory or-resistant patients with recurrent epithelial ovarian, primary fallopian tube, or primary peritoneal cancer. J Clin Oncol. 2012;30(31):3841-3847.
-
(2012)
J Clin Oncol.
, vol.30
, Issue.31
, pp. 3841-3847
-
-
Colombo, N.1
Kutarska, E.2
Dimopoulos, M.3
-
29
-
-
36849019301
-
Phase II trial of bevacizumab in persistent or recurrent epithelial ovarian cancer or primary peritoneal cancer: A Gynecologic Oncology Group Study
-
Burger RA, Sill MW, Monk BJ, Greer BE, Sorosky JI. Phase II trial of bevacizumab in persistent or recurrent epithelial ovarian cancer or primary peritoneal cancer: a Gynecologic Oncology Group Study. J Clin Oncol. 2007;25(33):5165-5171.
-
(2007)
J Clin Oncol.
, vol.25
, Issue.33
, pp. 5165-5171
-
-
Burger, R.A.1
Sill, M.W.2
Monk, B.J.3
Greer, B.E.4
Sorosky, J.I.5
-
30
-
-
84866493383
-
AURELIA: A randomized phase III trial evaluating bevacizumab (BEV) plus chemotherapy (CT) for platinum (PT)-resistant recurrent ovarian cancer (OC)
-
abstract
-
Pujade-Lauraine E, Hilpert F, Weber B, et al. AURELIA: A randomized phase III trial evaluating bevacizumab (BEV) plus chemotherapy (CT) for platinum (PT)-resistant recurrent ovarian cancer (OC). J Clin Oncol. 2012;30(Suppl 15):abstract LBA5002.
-
(2012)
J Clin Oncol.
, vol.30
, Issue.SUPPL. 15
-
-
Pujade-Lauraine, E.1
Hilpert, F.2
Weber, B.3
-
31
-
-
84858245055
-
Phase II multi-institutional study of docetaxel plus aflibercept (AVE0005, NSC# 724770) in patients with recurrent ovarian, primary peritoneal, and fallopian tube cancer
-
Abstract
-
Coleman RL, Duska LR, Ramirez PT, et al. Phase II multi-institutional study of docetaxel plus aflibercept (AVE0005, NSC# 724770) in patients with recurrent ovarian, primary peritoneal, and fallopian tube cancer. J Clin Oncol. 2011;29(Suppl 15): Abstract 5017.
-
(2011)
J Clin Oncol.
, vol.29
, Issue.SUPPL. 15
, pp. 5017
-
-
Coleman, R.L.1
Duska, L.R.2
Ramirez, P.T.3
-
32
-
-
77954032829
-
Poly(ADP)-ribose polymerase inhibition: Frequent durable responses in BRCA carrier ovarian cancer correlating with platinum-free interval
-
Fong PC, Yap TA, Boss DS, et al. Poly(ADP)-ribose polymerase inhibition: frequent durable responses in BRCA carrier ovarian cancer correlating with platinum-free interval. J Clin Oncol. 2010;28(15): 2512-2519.
-
(2010)
J Clin Oncol.
, vol.28
, Issue.15
, pp. 2512-2519
-
-
Fong, P.C.1
Yap, T.A.2
Boss, D.S.3
-
33
-
-
84863010984
-
Phase II, open-label, randomized, multicenter study comparing the efficacy and safety of olaparib, a poly (ADP-ribose) polymerase inhibitor, and pegylated liposomal doxorubicin in patients with BRCA1 or BRCA2 mutations and recurrent ovarian cancer
-
Kaye SB, Lubinski J, Matulonis U, et al. Phase II, open-label, randomized, multicenter study comparing the efficacy and safety of olaparib, a poly (ADP-ribose) polymerase inhibitor, and pegylated liposomal doxorubicin in patients with BRCA1 or BRCA2 mutations and recurrent ovarian cancer. J Clin Oncol. 2012;30(4):372-379.
-
(2012)
J Clin Oncol.
, vol.30
, Issue.4
, pp. 372-379
-
-
Kaye, S.B.1
Lubinski, J.2
Matulonis, U.3
-
34
-
-
80053600436
-
A phase II trial of iniparib (BSI-201) in combination with gemcitabine/carboplatin (GC) in patients with platinum-resistant recurrent ovarian cancer
-
Abstract
-
Birrer MJ, Konstantinopoulos P, Penson RT, et al. A phase II trial of iniparib (BSI-201) in combination with gemcitabine/carboplatin (GC) in patients with platinum-resistant recurrent ovarian cancer. J Clin Oncol. 2011;29(Suppl): Abstract 5005.
-
(2011)
J Clin Oncol.
, vol.29
, Issue.SUPPL.
, pp. 5005
-
-
Birrer, M.J.1
Konstantinopoulos, P.2
Penson, R.T.3
-
35
-
-
66849114911
-
Phase II evaluation of pemetrexed in the treatment of recurrent or persistent platinum-resistant ovarian or primary peritoneal carcinoma: A study of the Gynecologic Oncology Group
-
Miller DS, Blessing JA, Krasner CN, et al. Phase II evaluation of pemetrexed in the treatment of recurrent or persistent platinum-resistant ovarian or primary peritoneal carcinoma: a study of the Gynecologic Oncology Group. J Clin Oncol. 2009;27(16):2686-2691.
-
(2009)
J Clin Oncol.
, vol.27
, Issue.16
, pp. 2686-2691
-
-
Miller, D.S.1
Blessing, J.A.2
Krasner, C.N.3
-
36
-
-
65249113396
-
A randomised, double-blind, phase II study of two doses of pemetrexed in the treatment of platinum-resistant, epithelial ovarian or primary peritoneal cancer
-
Vergote I, Calvert H, Kania M, Kaiser C, Zimmermann AH, Sehouli J. A randomised, double-blind, phase II study of two doses of pemetrexed in the treatment of platinum-resistant, epithelial ovarian or primary peritoneal cancer. Eur J Cancer. 2009;45:1415-1423.
-
(2009)
Eur J Cancer.
, vol.45
, pp. 1415-1423
-
-
Vergote, I.1
Calvert, H.2
Kania, M.3
Kaiser, C.4
Zimmermann, A.H.5
Sehouli, J.6
-
37
-
-
84891854386
-
PRECEDENT: A randomized phase II trial comparing EC145 and pegylated liposomal doxorubicin (PLD) in combination, versus PLD alone, in subjects with platinum-resistant ovarian cancer
-
In press
-
Naumann RW, Coleman RL, Burger RA, et al. PRECEDENT: a randomized phase II trial comparing EC145 and pegylated liposomal doxorubicin (PLD) in combination, versus PLD alone, in subjects with platinum-resistant ovarian cancer. J Clin Oncol. 2013. In press.
-
(2013)
J Clin Oncol
-
-
Naumann, R.W.1
Coleman, R.L.2
Burger, R.A.3
-
38
-
-
59449084872
-
Maintenance treatment with bevacizumab prolongs survival in an in vivo ovarian cancer model
-
Mabuchi S, Terai Y, Morishige K, et al. Maintenance treatment with bevacizumab prolongs survival in an in vivo ovarian cancer model. Clin Cancer Res. 2008;14(23):7781-7789.
-
(2008)
Clin Cancer Res.
, vol.14
, Issue.23
, pp. 7781-7789
-
-
Mabuchi, S.1
Terai, Y.2
Morishige, K.3
-
39
-
-
84866479731
-
Bevacizumab in the treatment of ovarian cancer
-
Heitz F, Harter P, Barinoff J, et al. Bevacizumab in the treatment of ovarian cancer. Adv Ther. 2012;29(9):723-735.
-
(2012)
Adv Ther.
, vol.29
, Issue.9
, pp. 723-735
-
-
Heitz, F.1
Harter, P.2
Barinoff, J.3
-
40
-
-
84855425106
-
Incorporation of bevacizumab in the primary treatment of ovarian cancer
-
Gynecologic Oncology Group
-
Burger RA, Brady MF, Bookman MA, et al; Gynecologic Oncology Group. Incorporation of bevacizumab in the primary treatment of ovarian cancer. N Engl J Med. 2011;365(26):2473-2483.
-
(2011)
N Engl J Med.
, vol.365
, Issue.26
, pp. 2473-2483
-
-
Burger, R.A.1
Brady, M.F.2
Bookman, M.A.3
-
41
-
-
84855466019
-
A phase 3 trial of bevacizumab in ovarian cancer
-
ICON7 Investigators
-
Perren TJ, Swart AM, Pfisterer J, et al; ICON7 Investigators. A phase 3 trial of bevacizumab in ovarian cancer. N Engl J Med. 2011;365(26): 2484-2496.
-
(2011)
N Engl J Med.
, vol.365
, Issue.26
, pp. 2484-2496
-
-
Perren, T.J.1
Swart, A.M.2
Pfisterer, J.3
-
42
-
-
84875339336
-
Aflibercept: A novel VEGF targeted agent to explore the future perspectives of anti-angiogenic therapy for the treatment of multiple tumors
-
Sharma T, Dhingra R, Singh S, et al. Aflibercept: A novel VEGF targeted agent to explore the future perspectives of anti-angiogenic therapy for the treatment of multiple tumors. Mini Rev Med Chem. 2013;13(4):530-540.
-
(2013)
Mini Rev Med Chem.
, vol.13
, Issue.4
, pp. 530-540
-
-
Sharma, T.1
Dhingra, R.2
Singh, S.3
-
43
-
-
81255185158
-
Phase 1-2 study of docetaxel plus aflibercept in patients with recurrent ovarian, primary peritoneal, or fallopian tube cancer
-
Coleman RL, Duska LR, Ramirez PT, et al. Phase 1-2 study of docetaxel plus aflibercept in patients with recurrent ovarian, primary peritoneal, or fallopian tube cancer. Lancet Oncol. 2011;12(12):1109-1117.
-
(2011)
Lancet Oncol.
, vol.12
, Issue.12
, pp. 1109-1117
-
-
Coleman, R.L.1
Duska, L.R.2
Ramirez, P.T.3
-
44
-
-
84868527016
-
Phase II clinical and pharmacokinetic study of aflibercept in patients with previously treated metastatic colorectal cancer
-
Tang PA, Cohen SJ, Kollmannsberger C, et al. Phase II clinical and pharmacokinetic study of aflibercept in patients with previously treated metastatic colorectal cancer. Clin Cancer Res. 2012;18(21): 6023-6031.
-
(2012)
Clin Cancer Res.
, vol.18
, Issue.21
, pp. 6023-6031
-
-
Tang, P.A.1
Cohen, S.J.2
Kollmannsberger, C.3
-
45
-
-
31044446360
-
PARP inhibitors for cancer therapy
-
Curtin NJ. PARP inhibitors for cancer therapy. Expert Rev Mol Med. 2005;7(4):1-20.
-
(2005)
Expert Rev Mol Med.
, vol.7
, Issue.4
, pp. 1-20
-
-
Curtin, N.J.1
-
46
-
-
84865519032
-
Poly (ADP-ribose) polymerase inhibitors: On the horizon of tailored and personalized therapies for epithelial ovarian cancer
-
Ratner ES, Sartorelli AC, Lin ZP. Poly (ADP-ribose) polymerase inhibitors: on the horizon of tailored and personalized therapies for epithelial ovarian cancer. Curr Opin Oncol. 2012;24(5):564-571.
-
(2012)
Curr Opin Oncol.
, vol.24
, Issue.5
, pp. 564-571
-
-
Ratner, E.S.1
Sartorelli, A.C.2
Lin, Z.P.3
-
47
-
-
84862907868
-
Iniparib nonselectively modifies cysteine-containing proteins in tumor cells and is not a bona fide PARP inhibitor
-
Liu X, Shi Y, Maag DX, et al. Iniparib nonselectively modifies cysteine-containing proteins in tumor cells and is not a bona fide PARP inhibitor. Clin Cancer Res. 2012;18(2):510-523.
-
(2012)
Clin Cancer Res.
, vol.18
, Issue.2
, pp. 510-523
-
-
Liu, X.1
Shi, Y.2
Maag, D.X.3
-
48
-
-
77955039099
-
Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and recurrent ovarian cancer: A proof-of-concept trial
-
Audeh MW, Carmichael J, Penson RT, et al. Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and recurrent ovarian cancer: a proof-of-concept trial. Lancet. 2010;376.(9737):245-251.
-
(2010)
Lancet.
, vol.376
, Issue.9737
, pp. 245-251
-
-
Audeh, M.W.1
Carmichael, J.2
Penson, R.T.3
-
49
-
-
84880811116
-
Olaparib: A promising PARP inhibitor in ovarian cancer therapy
-
Epub April 26
-
Chen Y, Zhang L, Hao Q. Olaparib: a promising PARP inhibitor in ovarian cancer therapy. Arch Gynecol Obstet. Epub April 26, 2013.
-
(2013)
Arch Gynecol Obstet
-
-
Chen, Y.1
Zhang, L.2
Hao, Q.3
-
50
-
-
0026652116
-
The biological chemistry of folate receptors
-
Antony AC. The biological chemistry of folate receptors. Blood. 1992;79(11):2807-2820.
-
(1992)
Blood.
, vol.79
, Issue.11
, pp. 2807-2820
-
-
Antony, A.C.1
-
51
-
-
33947361166
-
The molecular identity and characterization of a Proton-coupled Folate Transporter-PCFT; biological ramifications and impact on the activity of pemetrexed
-
Zhao R, Goldman ID. The molecular identity and characterization of a Proton-coupled Folate Transporter-PCFT; biological ramifications and impact on the activity of pemetrexed. Cancer Metastasis Rev. 2007;26(1):129-139.
-
(2007)
Cancer Metastasis Rev.
, vol.26
, Issue.1
, pp. 129-139
-
-
Zhao, R.1
Goldman, I.D.2
-
52
-
-
0032950347
-
Enzyme inhibition, polyglutamation, and the effect of LY231514 (MTA) in purine biosynthesis
-
Mendelsohn LG, Shih C, Chen VJ, Habeck LL, Gates SB, Shackelford KA. Enzyme inhibition, polyglutamation, and the effect of LY231514 (MTA) in purine biosynthesis. Semin Oncol. 1999;26(2 Suppl 6):42-47.
-
(1999)
Semin Oncol.
, vol.26
, Issue.2 SUPPL. 6
, pp. 42-47
-
-
Mendelsohn, L.G.1
Shih, C.2
Chen, V.J.3
Habeck, L.L.4
Gates, S.B.5
Shackelford, K.A.6
-
53
-
-
0030976709
-
Simultaneous activity of two different mechanisms of folate transport in ovarian carcinoma cell lines
-
Miotti S, Bagnoli M, Ottone F, Tomassetti A, Colnaghi MI, Canevari S. Simultaneous activity of two different mechanisms of folate transport in ovarian carcinoma cell lines. J Cell Biochem. 1997;65(4):479-491.
-
(1997)
J Cell Biochem.
, vol.65
, Issue.4
, pp. 479-491
-
-
Miotti, S.1
Bagnoli, M.2
Ottone, F.3
Tomassetti, A.4
Colnaghi, M.I.5
Canevari, S.6
-
54
-
-
73349089623
-
Emerging role of pemetrexed in ovarian cancer
-
Tomao F, Panici PB, Frati L, Tomao S. Emerging role of pemetrexed in ovarian cancer. Expert Rev Anticancer Ther. 2009;9(12):1727-1735.
-
(2009)
Expert Rev Anticancer Ther.
, vol.9
, Issue.12
, pp. 1727-1735
-
-
Tomao, F.1
Panici, P.B.2
Frati, L.3
Tomao, S.4
-
55
-
-
84868697449
-
Paradoxical impact of two folate receptors, FRα and RFC, in ovarian cancer: Effect on cell proliferation, invasion and clinical outcome
-
Siu MK, Kong DS, Chan HY, et al. Paradoxical impact of two folate receptors, FRα and RFC, in ovarian cancer: effect on cell proliferation, invasion and clinical outcome. PloS One. 2012;7(11):e47201.
-
(2012)
PloS One.
, vol.7
, Issue.11
-
-
Siu, M.K.1
Kong, D.S.2
Chan, H.Y.3
-
56
-
-
0036562507
-
Homocysteine and methylmalonic acid: Markers to predict and avoid toxicity from pemetrexed therapy
-
Niyikiza C, Baker SD, Seitz DE, et al. Homocysteine and methylmalonic acid: markers to predict and avoid toxicity from pemetrexed therapy. Mol Cancer Ther. 2002;1(7):545-552.
-
(2002)
Mol Cancer Ther.
, vol.1
, Issue.7
, pp. 545-552
-
-
Niyikiza, C.1
Baker, S.D.2
Seitz, D.E.3
-
57
-
-
3042575322
-
Pemetrexed (ALIMTA), a novel multitargeted neoplastic agent
-
Adjei AA. Pemetrexed (ALIMTA), a novel multitargeted neoplastic agent. Clin Cancer Res. 2004;10(12 Pt):4276s-4280s.
-
(2004)
Clin Cancer Res.
, vol.10
, Issue.12 PART
-
-
Adjei, A.A.1
-
58
-
-
79960481261
-
Mechanisms of membrane transport of folates into cells and across epithelia
-
Zhao R, Diop-Bove N, Visentin M, Goldman ID. Mechanisms of membrane transport of folates into cells and across epithelia. Annu Rev Nutr. 2011;31:177-201.
-
(2011)
Annu Rev Nutr.
, vol.31
, pp. 177-201
-
-
Zhao, R.1
Diop-Bove, N.2
Visentin, M.3
Goldman, I.D.4
-
59
-
-
84863483737
-
Farletuzumab, an anti-folate receptor α antibody, does not block binding of folate or anti-folates to receptor nor does it alter the potency of anti-folates in vitro
-
Kamen BA, Smith AK. Farletuzumab, an anti-folate receptor α antibody, does not block binding of folate or anti-folates to receptor nor does it alter the potency of anti-folates in vitro. Cancer Chemother Pharmacol. 2012;70(1):113-120.
-
(2012)
Cancer Chemother Pharmacol.
, vol.70
, Issue.1
, pp. 113-120
-
-
Kamen, B.A.1
Smith, A.K.2
-
60
-
-
33947166337
-
Preclinical evaluation of MORAb-003, a humanized monoclonal antibody antagonizing folate receptor-alpha
-
Ebel W, Routhier EL, Foley B, et al. Preclinical evaluation of MORAb-003, a humanized monoclonal antibody antagonizing folate receptor-alpha. Cancer Immun. 2007;7:6.
-
(2007)
Cancer Immun.
, vol.7
, pp. 6
-
-
Ebel, W.1
Routhier, E.L.2
Foley, B.3
-
61
-
-
78049476593
-
Farletuzumab, a humanized monoclonal antibody against folate receptor alpha, in epithelial ovarian cancer: A phase I study
-
Konner JA, Bell-McGuinn KM, Sabbatini P, et al. Farletuzumab, a humanized monoclonal antibody against folate receptor alpha, in epithelial ovarian cancer: a phase I study. Clin Cancer Res. 2010;16(1):5288-5295.
-
(2010)
Clin Cancer Res.
, vol.16
, Issue.1
, pp. 5288-5295
-
-
Konner, J.A.1
Bell-McGuinn, K.M.2
Sabbatini, P.3
-
62
-
-
79952746215
-
EC-145, a folate-targeted Vinca alkaloid conjugate for the potential treatment of folate receptor-expressing cancers
-
Dosio F, Milla P, Cattel L. EC-145, a folate-targeted Vinca alkaloid conjugate for the potential treatment of folate receptor-expressing cancers. Curr Opin Investig Drugs. 2010;11(12):1424-1433.
-
(2010)
Curr Opin Investig Drugs.
, vol.11
, Issue.12
, pp. 1424-1433
-
-
Dosio, F.1
Milla, P.2
Cattel, L.3
-
63
-
-
33747349484
-
Design and regioselective synthesis of a new generation of targeted chemotherapeutics. Part 1: EC145, a folic acid conjugate of desacetylvinblastine monohydrazide
-
Vlahov IR, Santhapuram HK, Kleindl PJ, Howard SJ, Stanford KM, Leamon CP. Design and regioselective synthesis of a new generation of targeted chemotherapeutics. Part 1: EC145, a folic acid conjugate of desacetylvinblastine monohydrazide. Bioorg Med Chem Lett. 2006;16(19):5093-5096.
-
(2006)
Bioorg Med Chem Lett.
, vol.16
, Issue.19
, pp. 5093-5096
-
-
Vlahov, I.R.1
Santhapuram, H.K.2
Kleindl, P.J.3
Howard, S.J.4
Stanford, K.M.5
Leamon, C.P.6
-
64
-
-
84863946983
-
Engineering folate-drug conjugates to target cancer: From chemistry to clinic
-
Vlahov IR, Leamon CP. Engineering folate-drug conjugates to target cancer: from chemistry to clinic. Bioconjug Chem. 2012;23(7): 1357-1369.
-
(2012)
Bioconjug Chem.
, vol.23
, Issue.7
, pp. 1357-1369
-
-
Vlahov, I.R.1
Leamon, C.P.2
-
65
-
-
0036862058
-
Synthesis and biological evaluation of EC20: A new folate-derived, (99 m)Tc-based radiopharmaceutical
-
Leamon CP, Parker MA, Vlahov IR, et al. Synthesis and biological evaluation of EC20: a new folate-derived, (99 m)Tc-based radiopharmaceutical. Bioconjug Chem. 2002;13(6):1200-1210.
-
(2002)
Bioconjug Chem.
, vol.13
, Issue.6
, pp. 1200-1210
-
-
Leamon, C.P.1
Parker, M.A.2
Vlahov, I.R.3
-
66
-
-
2642514921
-
Preclinical evaluation of (99m)Tc-EC20 for imaging folate receptor-positive tumors
-
Reddy JA, Xu LC, Parker N, Vetzel M, Leamon CP. Preclinical evaluation of (99m)Tc-EC20 for imaging folate receptor-positive tumors. J Nucl Med. 2004;45(5):857-866.
-
(2004)
J Nucl Med.
, vol.45
, Issue.5
, pp. 857-866
-
-
Reddy, J.A.1
Xu, L.C.2
Parker, N.3
Vetzel, M.4
Leamon, C.P.5
-
67
-
-
44849127008
-
Exploratory study of 99mTc-EC20 imaging for identifying patients with folate receptor-positive solid tumors
-
Fisher RE, Siegel BA, Edell SL, et al. Exploratory study of 99mTc-EC20 imaging for identifying patients with folate receptor-positive solid tumors. J Nucl Med. 2008;49(6):899-906.
-
(2008)
J Nucl Med.
, vol.49
, Issue.6
, pp. 899-906
-
-
Fisher, R.E.1
Siegel, B.A.2
Edell, S.L.3
-
68
-
-
84862808121
-
Serous ovarian carcinoma patients with high alpha-folate receptor had reducing survival and cytotoxic chemo-response
-
Chen YL, Chang MC, Huang CY, et al. Serous ovarian carcinoma patients with high alpha-folate receptor had reducing survival and cytotoxic chemo-response. Mol Oncol. 2012;6(3):360-369.
-
(2012)
Mol Oncol.
, vol.6
, Issue.3
, pp. 360-369
-
-
Chen, Y.L.1
Chang, M.C.2
Huang, C.Y.3
-
69
-
-
82555202337
-
-
South San Francisco, CA: Genentech, Inc; Available from:. Accessed April 22, 2013
-
Herceptin [prescribing information]. South San Francisco, CA: Genentech, Inc; 2010. Available from: http://www.accessdata.fda.gov/drugsatfda_docs/label/2010/103792s5250lbl.pdf. Accessed April 22, 2013.
-
(2010)
Herceptin [prescribing information]
-
-
-
70
-
-
34249908675
-
-
South San Francisco, CA: Genentech, Inc; Available from:. Accessed April 22, 2013
-
Zelboraf [prescribing information]. South San Francisco, CA: Genentech, Inc; 2011. Available from: http://www.accessdata.fda.gov/drugsatfda_docs/label/2011/202429s000lbl.pdf. Accessed April 22, 2013.
-
(2011)
Zelboraf [prescribing information].
-
-
-
71
-
-
79959795786
-
Improved survival with vemurafenib in melanoma with BRAF V600E mutation
-
Chapman PB, Hauschild A, Robert C, et al. Improved survival with vemurafenib in melanoma with BRAF V600E mutation. N Engl J Med. 2011;364(26):2507-2516.
-
(2011)
N Engl J Med.
, vol.364
, Issue.26
, pp. 2507-2516
-
-
Chapman, P.B.1
Hauschild, A.2
Robert, C.3
-
72
-
-
0031684721
-
The HER-2/neu oncogene in breast cancer: Prognostic factor, predictive factor, and target for therapy
-
Ross JS, Fletcher JA. The HER-2/neu oncogene in breast cancer: prognostic factor, predictive factor, and target for therapy. Oncologist. 1998;3(4):237-252.
-
(1998)
Oncologist.
, vol.3
, Issue.4
, pp. 237-252
-
-
Ross, J.S.1
Fletcher, J.A.2
-
73
-
-
84867298938
-
The prognostic value of BRAF mutation in colorectal cancer and melanoma: A systematic review and meta-analysis
-
Safaee Ardekani G, Jafarnejad SM, Tan L, Saeedi A, Li G. The prognostic value of BRAF mutation in colorectal cancer and melanoma: a systematic review and meta-analysis. PLoS One. 2012;7(10):e47054.
-
(2012)
PLoS One.
, vol.7
, Issue.10
-
-
Safaee Ardekani, G.1
Jafarnejad, S.M.2
Tan, L.3
Saeedi, A.4
Li, G.5
-
74
-
-
56449098987
-
Serum and tissue biomarkers as predictive and prognostic variables in epithelial ovarian cancer
-
Gadducci A, Cosio S, Tana R, Genazanni AR. Serum and tissue biomarkers as predictive and prognostic variables in epithelial ovarian cancer. Crit Rev Oncol Hematol. 2009;69(1):12-27.
-
(2009)
Crit Rev Oncol Hematol.
, vol.69
, Issue.1
, pp. 12-27
-
-
Gadducci, A.1
Cosio, S.2
Tana, R.3
Genazanni, A.R.4
-
75
-
-
84858217607
-
Cancer antigen 125: Lost to follow-up?: A European society of gynaecological oncology consensus statement
-
Council of the European Society of Gynaecologic Oncology
-
Verheijen RH, Cibula D, Zola P, et al; Council of the European Society of Gynaecologic Oncology. Cancer antigen 125: lost to follow-up?: a European society of gynaecological oncology consensus statement. Int J Gynecol Cancer. 2012;22(1):170-174.
-
(2012)
Int J Gynecol Cancer.
, vol.22
, Issue.1
, pp. 170-174
-
-
Verheijen, R.H.1
Cibula, D.2
Zola, P.3
-
76
-
-
33751006991
-
Preoperative serum vascular endothelial growth factor as a prognostic parameter in ovarian cancer
-
Hefler LA, Zeillinger R, Grimm C, et al. Preoperative serum vascular endothelial growth factor as a prognostic parameter in ovarian cancer. Gynecol Oncol. 2006;103(2):512-517.
-
(2006)
Gynecol Oncol.
, vol.103
, Issue.2
, pp. 512-517
-
-
Hefler, L.A.1
Zeillinger, R.2
Grimm, C.3
-
77
-
-
84866275588
-
Serial measurements of serum PDGF-AA, PDGF-BB, FGF2, and VEGF in multiresistant ovarian cancer patients treated with bevacizumab
-
Madsen CV, Steffensen KD, Olsen DA, et al. Serial measurements of serum PDGF-AA, PDGF-BB, FGF2, and VEGF in multiresistant ovarian cancer patients treated with bevacizumab. J Ovarian Res. 2012;5(1):23.
-
(2012)
J Ovarian Res.
, vol.5
, Issue.1
, pp. 23
-
-
Madsen, C.V.1
Steffensen, K.D.2
Olsen, D.A.3
-
78
-
-
80052389761
-
Olaparib in patients with recurrent high-grade serous or poorly differentiated ovarian carcinoma or triple-negative breast cancer: A phase 2, multicenter, open-label, non-randomised study
-
Gelmon KA, Tischkowitz M, Mackay H, et al. Olaparib in patients with recurrent high-grade serous or poorly differentiated ovarian carcinoma or triple-negative breast cancer: a phase 2, multicenter, open-label, non-randomised study. Lancet Oncol. 2011;12(9):852-861.
-
(2011)
Lancet Oncol.
, vol.12
, Issue.9
, pp. 852-861
-
-
Gelmon, K.A.1
Tischkowitz, M.2
McKay, H.3
-
79
-
-
84866625235
-
Multicenter trial of EC145 in advanced, folate-receptor positive adenocarcinoma of the lung
-
Edelman MJ, Harb WA, Pal SE, et al. Multicenter trial of EC145 in advanced, folate-receptor positive adenocarcinoma of the lung. J Thorac Oncol. 2012;7(10):1618-1621.
-
(2012)
J Thorac Oncol.
, vol.7
, Issue.10
, pp. 1618-1621
-
-
Edelman, M.J.1
Harb, W.A.2
Pal, S.E.3
-
80
-
-
84884757808
-
99 mTc-etarfolatide (EC20) SPECT imaging for the identification of ovarian and non-small cell lung cancer patients who are most likely to benefit from folate-receptor-targeted agent vintafolide (EC145)
-
February 27-March 2, San Diego, CA, USA. abstract 41
-
Kuo P, Naumann RW, Symanowski J, et al. 99 mTc-etarfolatide (EC20) SPECT imaging for the identification of ovarian and non-small cell lung cancer patients who are most likely to benefit from folate-receptor-targeted agent vintafolide (EC145). AACR-SNMMI Joint Conference on State-of-the-Art Molecular Imaging in Cancer and Biology Therapy; February 27-March 2, 2013; San Diego, CA, USA. abstract 41.
-
(2013)
AACR-SNMMI Joint Conference on State-of-the-Art Molecular Imaging in Cancer and Biology Therapy
-
-
Kuo, P.1
Naumann, R.W.2
Symanowski, J.3
-
81
-
-
0030910859
-
Overexpression of folate binding protein in ovarian cancers
-
Toffoli G, Cernigoi C, Russo A, Gallo A, Bagnoli M, Boiocchi M. Overexpression of folate binding protein in ovarian cancers. Int J Cancer. 1997;74(2):193-198.
-
(1997)
Int J Cancer.
, vol.74
, Issue.2
, pp. 193-198
-
-
Toffoli, G.1
Cernigoi, C.2
Russo, A.3
Gallo, A.4
Bagnoli, M.5
Boiocchi, M.6
-
82
-
-
84884154318
-
FDA moves on breakthrough therapies
-
Fox JL. FDA moves on breakthrough therapies. Nat Biotechnol. 2013;31(5):374.
-
(2013)
Nat Biotechnol.
, vol.31
, Issue.5
, pp. 374
-
-
Fox, J.L.1
-
83
-
-
84884753450
-
EC0531: A potent folate-targeted tubulysin conjugate. Proceedings of the 101st Annual Meeting of the American Association for Cancer Research
-
abstract nr. April 17-21, 2010; Washington, DC. Philadelphia (PA): AACR
-
Leamon CP, Reddy JA, Wang Y, et al. EC0531: A potent folate-targeted tubulysin conjugate. Proceedings of the 101st Annual Meeting of the American Association for Cancer Research; April 17-21, 2010; Washington, DC. Philadelphia (PA): AACR; Cancer Res 2010; 70(Suppl 8):abstract nr 4414.
-
(2010)
Cancer Res
, vol.70
, Issue.SUPPL. 8
, pp. 4414
-
-
Leamon, C.P.1
Reddy, J.A.2
Wang, Y.3
-
84
-
-
84924114865
-
PSMA-specific anti-tumor activity of the targeted-tubulysin conjugate, EC1169
-
April 6-10, Washington, DC, USA. Philadelphia (PA): AACR; 2013
-
Reddy JA, Bloomfield A, Dorton R, et al. PSMA-specific anti-tumor activity of the targeted-tubulysin conjugate, EC1169. Proceedings of the 104th Annual Meeting of the American Association for Cancer Research; April 6-10, 2013; Washington, DC, USA. Philadelphia (PA): AACR; 2013.
-
(2013)
Proceedings of the 104th Annual Meeting of the American Association for Cancer Research
-
-
Reddy, J.A.1
Bloomfield, A.2
Dorton, R.3
|