-
1
-
-
33646577163
-
Genetics and biology of pancreatic ductal adenocarcinoma
-
Hezel AF, Kimmelman AC, Stanger BZ, Bardeesy N, Depinho RA, (2006) Genetics and biology of pancreatic ductal adenocarcinoma. Genes Dev 20: 1218-1249.
-
(2006)
Genes Dev
, vol.20
, pp. 1218-1249
-
-
Hezel, A.F.1
Kimmelman, A.C.2
Stanger, B.Z.3
Bardeesy, N.4
Depinho, R.A.5
-
2
-
-
84860112131
-
What we have learned about pancreatic cancer from mouse models
-
Perez-Mancera PA, Guerra C, Barbacid M, Tuveson DA, (2012) What we have learned about pancreatic cancer from mouse models. Gastroenterology 142: 1079-1092.
-
(2012)
Gastroenterology
, vol.142
, pp. 1079-1092
-
-
Perez-Mancera, P.A.1
Guerra, C.2
Barbacid, M.3
Tuveson, D.A.4
-
3
-
-
84857606982
-
New strategies and designs in pancreatic cancer research: consensus guidelines report from a European expert panel
-
van Laethem J-L, Verslype C, Iovanna JL, Michl P, Conroy T, et al. (2012) New strategies and designs in pancreatic cancer research: consensus guidelines report from a European expert panel. Ann Oncol 23: 570-576.
-
(2012)
Ann Oncol
, vol.23
, pp. 570-576
-
-
van Laethem, J.-L.1
Verslype, C.2
Iovanna, J.L.3
Michl, P.4
Conroy, T.5
-
4
-
-
52149123619
-
Core signaling pathways in human pancreatic cancers revealed by global genomic analyses
-
Jones S, Zhang X, Parson DW, Lin JC-H, Leary RJ, et al. (2008) Core signaling pathways in human pancreatic cancers revealed by global genomic analyses. Science 321: 1801-1806.
-
(2008)
Science
, vol.321
, pp. 1801-1806
-
-
Jones, S.1
Zhang, X.2
Parson, D.W.3
Lin, J.C.-H.4
Leary, R.J.5
-
5
-
-
77957150824
-
KRAS, Hedgehog, Wnt and the twisted developmental biology of pancreatic ductal adenocarcinoma
-
Morris JP IV, Wang SC, Hebrok M, (2010) KRAS, Hedgehog, Wnt and the twisted developmental biology of pancreatic ductal adenocarcinoma. Nat Rev Cancer 10: 683-695.
-
(2010)
Nat Rev Cancer
, vol.10
, pp. 683-695
-
-
Morris IV, J.P.1
Wang, S.C.2
Hebrok, M.3
-
7
-
-
0032943591
-
The nuclear factor-κB RelA transcription factor is constitutelively activated in human pancreatic adenocarcinoma cells
-
Wang W, Abbruzzese JL, Evans DB, Larry L, Cleary KR, et al. (1999) The nuclear factor-κB RelA transcription factor is constitutelively activated in human pancreatic adenocarcinoma cells. Clin Cancer Res 5: 119-127.
-
(1999)
Clin Cancer Res
, vol.5
, pp. 119-127
-
-
Wang, W.1
Abbruzzese, J.L.2
Evans, D.B.3
Larry, L.4
Cleary, K.R.5
-
8
-
-
0037242595
-
Function of nuclear factor κB in pancreatic cancer metastasis
-
Fujioka S, Sclabas GM, Schmidt C, Frederick WA, Dong QG, et al. (2003) Function of nuclear factor κB in pancreatic cancer metastasis. Clin Cancer Res 9: 346-354.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 346-354
-
-
Fujioka, S.1
Sclabas, G.M.2
Schmidt, C.3
Frederick, W.A.4
Dong, Q.G.5
-
9
-
-
1842850737
-
Increased expression of NF-κB subunits in human pancreatic cancer cells
-
Chandler NM, Canete JJ, Callery MP, (2004) Increased expression of NF-κB subunits in human pancreatic cancer cells. J Surg Res 118: 9-14.
-
(2004)
J Surg Res
, vol.118
, pp. 9-14
-
-
Chandler, N.M.1
Canete, J.J.2
Callery, M.P.3
-
10
-
-
67349162130
-
Tumor necrosis factor and cancer
-
Balkwill F, (2009) Tumor necrosis factor and cancer. Nat Rev Cancer 9: 361-371.
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 361-371
-
-
Balkwill, F.1
-
11
-
-
77649286829
-
The role of TNF in cancer
-
Wajant H, (2009) The role of TNF in cancer. Results Probl Cell Differ 49: 1-15.
-
(2009)
Results Probl Cell Differ
, vol.49
, pp. 1-15
-
-
Wajant, H.1
-
12
-
-
0028866022
-
The transmembrane form of tumor necrosis factor is the prime activating ligand of the 80 kDa tumor necrosis factor receptor
-
Grell M, Douni E, Wajant H, Löhden M, Clauss M, et al. (1995) The transmembrane form of tumor necrosis factor is the prime activating ligand of the 80 kDa tumor necrosis factor receptor. Cell 83: 793-802.
-
(1995)
Cell
, vol.83
, pp. 793-802
-
-
Grell, M.1
Douni, E.2
Wajant, H.3
Löhden, M.4
Clauss, M.5
-
14
-
-
34250864955
-
Interaction of TNF with TNF receptor type 2 promotes expansion and function of mouse CD4+CD25+ T regulatory cells
-
Chen X, Bäumel M, Männel DN, Howard OM, Oppenheim JJ, (2007) Interaction of TNF with TNF receptor type 2 promotes expansion and function of mouse CD4+CD25+ T regulatory cells. J Immunol 179: 154-161.
-
(2007)
J Immunol
, vol.179
, pp. 154-161
-
-
Chen, X.1
Bäumel, M.2
Männel, D.N.3
Howard, O.M.4
Oppenheim, J.J.5
-
15
-
-
84872690335
-
TNFR2 is critical for the stabilization of the CD4+Foxp3+ regulatory T cell phenotype in the inflammatory environment
-
Chen X, Wu X, Zhou Q, Howard OM, Netea MG, et al. (2013) TNFR2 is critical for the stabilization of the CD4+Foxp3+ regulatory T cell phenotype in the inflammatory environment. J Immunol 190: 1076-1084.
-
(2013)
J Immunol
, vol.190
, pp. 1076-1084
-
-
Chen, X.1
Wu, X.2
Zhou, Q.3
Howard, O.M.4
Netea, M.G.5
-
16
-
-
84878984966
-
Tumor necrosis factor receptor 2-dependent homeostasis of regulatory T cells as a player in TNF-induced experimental metastasis
-
Chopra M, Riedel SS, Biehl M, Krieger S, von Krosigk V, et al. (2013) Tumor necrosis factor receptor 2-dependent homeostasis of regulatory T cells as a player in TNF-induced experimental metastasis. Carcinogenesis 1296-1303.
-
(2013)
Carcinogenesis
, pp. 1296-1303
-
-
Chopra, M.1
Riedel, S.S.2
Biehl, M.3
Krieger, S.4
von Krosigk, V.5
-
17
-
-
40449090323
-
Anti-tumor necrosis factor therapy inhibits pancreatic tumor growth and metastasis
-
Egberts J-H, Cloosters V, Noack A, Schniewind B, Thon L, et al. (2008) Anti-tumor necrosis factor therapy inhibits pancreatic tumor growth and metastasis. Cancer Res 68: 1443-1450.
-
(2008)
Cancer Res
, vol.68
, pp. 1443-1450
-
-
Egberts, J.-H.1
Cloosters, V.2
Noack, A.3
Schniewind, B.4
Thon, L.5
-
18
-
-
44449137591
-
TNFR1 signaling and IFN-gamma signaling determine whether T cells induce tumor dormancy or promote multistage carcinogenesis
-
Müller-Hermelink N, Braunmüller H, Pichler B, Wieder T, Mailhammer R, et al. (2008) TNFR1 signaling and IFN-gamma signaling determine whether T cells induce tumor dormancy or promote multistage carcinogenesis. Cancer Cell 13: 507-518.
-
(2008)
Cancer Cell
, vol.13
, pp. 507-518
-
-
Müller-Hermelink, N.1
Braunmüller, H.2
Pichler, B.3
Wieder, T.4
Mailhammer, R.5
-
19
-
-
70350090156
-
Combination of human tumor necrosis factor-alpha (hTNF-α) gene delivery with gemcitabine is effective in models of pancreatic cancer
-
Murugesan SR, King CR, Osborn R, Fairweather WR, O'Reilly EM, et al. (2009) Combination of human tumor necrosis factor-alpha (hTNF-α) gene delivery with gemcitabine is effective in models of pancreatic cancer. Cancer Gene Ther 16: 841-847.
-
(2009)
Cancer Gene Ther
, vol.16
, pp. 841-847
-
-
Murugesan, S.R.1
King, C.R.2
Osborn, R.3
Fairweather, W.R.4
O'Reilly, E.M.5
-
20
-
-
77954030498
-
NF-κB promotes epithelial-mesenchymal transition, migration and invasion of pancreatic carcinoma cells
-
Maier HJ, Schmidt-Straßburger U, Huber MA, Wiedemann EM, Beug H, et al. (2010) NF-κB promotes epithelial-mesenchymal transition, migration and invasion of pancreatic carcinoma cells. Cancer Lett 295: 214-228.
-
(2010)
Cancer Lett
, vol.295
, pp. 214-228
-
-
Maier, H.J.1
Schmidt-Straßburger, U.2
Huber, M.A.3
Wiedemann, E.M.4
Beug, H.5
-
21
-
-
79955463604
-
Combination treatment using adenovirus vector-mediated tumor necrosis factor-alpha gene transfer and a NF-κB inhibitor for pancreatic cancer in mice
-
Furukawa K, Ohashi T, Haruki K, Fujiwara Y, Iida T, et al. (2011) Combination treatment using adenovirus vector-mediated tumor necrosis factor-alpha gene transfer and a NF-κB inhibitor for pancreatic cancer in mice. Cancer Lett 306: 92-98.
-
(2011)
Cancer Lett
, vol.306
, pp. 92-98
-
-
Furukawa, K.1
Ohashi, T.2
Haruki, K.3
Fujiwara, Y.4
Iida, T.5
-
22
-
-
79955481608
-
Impact of death receptor signaling on the malignancy of pancreatic ductal adenocarcinoma
-
Röder C, Trauzold A, Kalthoff H, (2011) Impact of death receptor signaling on the malignancy of pancreatic ductal adenocarcinoma. Eur J Cell Biol 90: 450-455.
-
(2011)
Eur J Cell Biol
, vol.90
, pp. 450-455
-
-
Röder, C.1
Trauzold, A.2
Kalthoff, H.3
-
23
-
-
0036967923
-
Resection of pancreatic cancer normalize the preoperative increase of tumor necrosis factor alpha gene expression
-
Ariapart P, Bergstedt-Lindqvist S, van Harmelen V, Permert J, Wang F, et al. (2012) Resection of pancreatic cancer normalize the preoperative increase of tumor necrosis factor alpha gene expression. Pancreatology 2: 491-494.
-
(2012)
Pancreatology
, vol.2
, pp. 491-494
-
-
Ariapart, P.1
Bergstedt-Lindqvist, S.2
van Harmelen, V.3
Permert, J.4
Wang, F.5
-
24
-
-
0021330445
-
Induction and chemotherapeutic response of two transplantable ductal adenocarcinoma of the pancreas in C57BL/6 mice
-
Corbett TH, Roberts BJ, Leopold WR, Peckham JC, Wilkoff LJ, et al. (1984) Induction and chemotherapeutic response of two transplantable ductal adenocarcinoma of the pancreas in C57BL/6 mice. Cancer Res 44: 717-726.
-
(1984)
Cancer Res
, vol.44
, pp. 717-726
-
-
Corbett, T.H.1
Roberts, B.J.2
Leopold, W.R.3
Peckham, J.C.4
Wilkoff, L.J.5
-
25
-
-
0348048858
-
Terminally modified oligodeoxynucleotides directed against p53 in an orthotopic xenograft model: a novel adjuvant treatment strategy for pancreatic ductal carcinoma
-
Tepel J, Kruse ML, March C, Fiedler A, Kapischke M, et al. (2004) Terminally modified oligodeoxynucleotides directed against p53 in an orthotopic xenograft model: a novel adjuvant treatment strategy for pancreatic ductal carcinoma. Pancreas 28: 1-12.
-
(2004)
Pancreas
, vol.28
, pp. 1-12
-
-
Tepel, J.1
Kruse, M.L.2
March, C.3
Fiedler, A.4
Kapischke, M.5
-
26
-
-
23044472871
-
In vivo analyses of early events in acute graft-versus-host disease reveal sequential infiltration of T-cell subsets
-
Beilhack A, Schulz S, Baker J, Beilhack GF, Wieland CB, et al. (2005) In vivo analyses of early events in acute graft-versus-host disease reveal sequential infiltration of T-cell subsets. Blood 106: 1113-1122.
-
(2005)
Blood
, vol.106
, pp. 1113-1122
-
-
Beilhack, A.1
Schulz, S.2
Baker, J.3
Beilhack, G.F.4
Wieland, C.B.5
-
27
-
-
0027534917
-
Enhancement of experimental metastasis by tumor necrosis factor
-
Orosz P, Echtenacher B, Falk W, Rüschoff J, Weber D, et al. (1993) Enhancement of experimental metastasis by tumor necrosis factor. J Exp Med 177: 1391-1398.
-
(1993)
J Exp Med
, vol.177
, pp. 1391-1398
-
-
Orosz, P.1
Echtenacher, B.2
Falk, W.3
Rüschoff, J.4
Weber, D.5
-
28
-
-
0029887296
-
TNF promotes metastasis by impairing natural killer cell activity
-
Hafner M, Orosz P, Krüger A, Männel DN, (1996) TNF promotes metastasis by impairing natural killer cell activity. Int J Cancer 66: 388-392.
-
(1996)
Int J Cancer
, vol.66
, pp. 388-392
-
-
Hafner, M.1
Orosz, P.2
Krüger, A.3
Männel, D.N.4
-
29
-
-
12144289781
-
TNF-α promotes progression of peritoneal metastasis as demonstrated using a green fluorescence protein (GFP)-tagged human gastric cancer cell line
-
Mochizuki Y, Nakanishi H, Kodera Y, Ito S, Yamamura Y, et al. (2004) TNF-α promotes progression of peritoneal metastasis as demonstrated using a green fluorescence protein (GFP)-tagged human gastric cancer cell line. Clin Exp Metastasis 21: 39-47.
-
(2004)
Clin Exp Metastasis
, vol.21
, pp. 39-47
-
-
Mochizuki, Y.1
Nakanishi, H.2
Kodera, Y.3
Ito, S.4
Yamamura, Y.5
-
30
-
-
80051950689
-
TNF receptor 1 deficiency increases regulatory T cell function in nonobese diabetic mice
-
Chee J, Angstetra E, Mariana L, Graham KL, Carrington EM, et al. (2011) TNF receptor 1 deficiency increases regulatory T cell function in nonobese diabetic mice. J Immunol 187: 1702-1712.
-
(2011)
J Immunol
, vol.187
, pp. 1702-1712
-
-
Chee, J.1
Angstetra, E.2
Mariana, L.3
Graham, K.L.4
Carrington, E.M.5
-
31
-
-
0036337768
-
IL-4 induces characteristic Th2 responses even in the combined absence of IL-5, IL-9, and IL-13
-
Fallon PG, Jolin HE, Smith P, Emson CL, Townsend MJ, et al. (2002) IL-4 induces characteristic Th2 responses even in the combined absence of IL-5, IL-9, and IL-13. Immunity 17: 7-17.
-
(2002)
Immunity
, vol.17
, pp. 7-17
-
-
Fallon, P.G.1
Jolin, H.E.2
Smith, P.3
Emson, C.L.4
Townsend, M.J.5
-
32
-
-
0036645112
-
Targeting interleukin-4 receptors for effective pancreatic cancer therapy
-
Kawakami K, Kawakami M, Husain SR, Puri RK, (2002) Targeting interleukin-4 receptors for effective pancreatic cancer therapy. Cancer Res 62: 3575-3580.
-
(2002)
Cancer Res
, vol.62
, pp. 3575-3580
-
-
Kawakami, K.1
Kawakami, M.2
Husain, S.R.3
Puri, R.K.4
-
33
-
-
16244370983
-
Interleukin-4 enhances proliferation of human pancreatic cancer cells: evidence for autocrine and paracrine actions
-
Prokopchuk O, Liu Y, Henne-Bruns D, Kornmann M, (2005) Interleukin-4 enhances proliferation of human pancreatic cancer cells: evidence for autocrine and paracrine actions. Br J Cancer 14: 921-928.
-
(2005)
Br J Cancer
, vol.14
, pp. 921-928
-
-
Prokopchuk, O.1
Liu, Y.2
Henne-Bruns, D.3
Kornmann, M.4
-
34
-
-
84867144615
-
Tim-3/galectin-9 signaling pathway mediates T-cell dysfunction and predicts poor prognosis in patients with hepatitis B virus-associated hepatocellular carcinoma
-
Li H, Wu K, Tao K, Chen L, Zheng Q, et al. (2012) Tim-3/galectin-9 signaling pathway mediates T-cell dysfunction and predicts poor prognosis in patients with hepatitis B virus-associated hepatocellular carcinoma. Hepatology 56: 1342-1351.
-
(2012)
Hepatology
, vol.56
, pp. 1342-1351
-
-
Li, H.1
Wu, K.2
Tao, K.3
Chen, L.4
Zheng, Q.5
-
35
-
-
84868709396
-
Cell Surface Galectin-9 Expressing Th Cells Regulate Th17 and Foxp3+ Treg Development by Galectin-9 Secretion
-
Oomizu S, Arikawa T, Niki T, Kadowaki T, Ueno M, et al. (2012) Cell Surface Galectin-9 Expressing Th Cells Regulate Th17 and Foxp3+ Treg Development by Galectin-9 Secretion. PLoS ONE 7: e48574.
-
(2012)
PLoS ONE
, vol.7
-
-
Oomizu, S.1
Arikawa, T.2
Niki, T.3
Kadowaki, T.4
Ueno, M.5
-
36
-
-
1842610143
-
Increased expression of inducible nitric oxide synthase and cyclooxygenase-2 in pancreatic cancer
-
Franco L, Doria D, Bertazzoni E, Benini A, Bassi C, (2004) Increased expression of inducible nitric oxide synthase and cyclooxygenase-2 in pancreatic cancer. Prostaglandins Other Lipid Mediat 73: 51-58.
-
(2004)
Prostaglandins Other Lipid Mediat
, vol.73
, pp. 51-58
-
-
Franco, L.1
Doria, D.2
Bertazzoni, E.3
Benini, A.4
Bassi, C.5
-
37
-
-
49649100910
-
Increased expression of inducible nitric oxide synthase (iNOS) in N-nitrosobis(2-oxopropyl)amine-induced hamster pancreatic carcinogenesis and prevention of cancer development by ONO-1714, an iNOS inhibitor
-
Takahashi M, Kitahashi T, Ishigamori R, Mutoh M, Komiya M, et al. (2008) Increased expression of inducible nitric oxide synthase (iNOS) in N-nitrosobis(2-oxopropyl)amine-induced hamster pancreatic carcinogenesis and prevention of cancer development by ONO-1714, an iNOS inhibitor. Carcinogenesis 29: 1608-1613.
-
(2008)
Carcinogenesis
, vol.29
, pp. 1608-1613
-
-
Takahashi, M.1
Kitahashi, T.2
Ishigamori, R.3
Mutoh, M.4
Komiya, M.5
-
38
-
-
33746352042
-
Adjuvant treatment of pancreatic carcinoma in a clinically adapted mouse resection model
-
Tepel J, Kruse ML, Kapischke M, Haye S, Sipos B, et al. (2006) Adjuvant treatment of pancreatic carcinoma in a clinically adapted mouse resection model. Pancreatology 6: 240-247.
-
(2006)
Pancreatology
, vol.6
, pp. 240-247
-
-
Tepel, J.1
Kruse, M.L.2
Kapischke, M.3
Haye, S.4
Sipos, B.5
-
39
-
-
45949096809
-
Molecular biology of pancreatic cancer - new aspects and targets
-
Schneider G, Hamacher R, Eser S, Friess H, Schmid RM, et al. (2008) Molecular biology of pancreatic cancer - new aspects and targets. Anticancer Res 28: 1541-1550.
-
(2008)
Anticancer Res
, vol.28
, pp. 1541-1550
-
-
Schneider, G.1
Hamacher, R.2
Eser, S.3
Friess, H.4
Schmid, R.M.5
-
40
-
-
79958776238
-
Metastatic pancreatic cancer: old drugs, new paradigms
-
Conroy T, Gavoille C, Adenis A, (2011) Metastatic pancreatic cancer: old drugs, new paradigms. Curr Opin Oncol 23: 390-395.
-
(2011)
Curr Opin Oncol
, vol.23
, pp. 390-395
-
-
Conroy, T.1
Gavoille, C.2
Adenis, A.3
|