Mechanisms of permanent loss of olfactory receptor neurons induced by the herbicide 2,6-dichlorobenzonitrile: Effects on stem cells and noninvolvement of acute induction of the inflammatory cytokine IL-6

Toxicology and Applied Pharmacology

Volumn 272, Issue 3, 2013, Pages 598-607

  Xie, Fang ^a,d   Fang, Cheng ^a,d   Schnittke, Nikolai ^b,c   Schwob, James E ^b   Ding, Xinxin ^a,d  

^a WADSWORTH CENTER   (United States)

^b STATE UNIVERSITY OF NEW YORK   (United States)

^c TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d TUFTS UNIVERSITY   (United States)

Author keywords

Dichlobenil; Inflammatory cytokines; Methimazole; Neurodegeneration; Olfactory stem cells; Regeneration

Indexed keywords

DEXAMETHASONE; DICHLOBENIL; INTERLEUKIN 6; THIAMAZOLE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BASAL CELL; BASEMENT MEMBRANE; CELL REGENERATION; CONTROLLED STUDY; DISEASE SEVERITY; FEMALE; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; MALE; METAPLASIA; MOUSE; NEUROEPITHELIUM; NONHUMAN; NOSE CAVITY; OLFACTORY EPITHELIUM; OLFACTORY RECEPTOR; PROTEIN INDUCTION; RESPIRATORY EPITHELIUM; RESPIRATORY TRACT DISEASE; STEM CELL;

2,6-DICHLOROBENZONITRILE (OR DICHLOBENIL); DCBN; DEX; DEXAMETHASONE; DICHLOBENIL; DMM; DORSAL MEDIAL MEATUS; HBCS; HORIZONTAL BASAL CELLS; IFN; IL; INFLAMMATORY CYTOKINES; INTERFERON; INTERLEUKIN; K5; KERATIN 5; METHIMAZOLE; MMZ; NEURODEGENERATION; OE; OLFACTORY EPITHELIUM; OLFACTORY MARKER PROTEIN; OLFACTORY RECEPTOR NEURONS; OLFACTORY STEM CELLS; OMP; ORNS; PBS; PHOSPHATE-BUFFERED SALINE; REGENERATION; TNF; TUMOR NECROSIS FACTOR;

ANIMALS; CELL COUNT; HERBICIDES; INFLAMMATION MEDIATORS; INTERLEUKIN-6; MICE; MICE, TRANSGENIC; NITRILES; OLFACTORY MUCOSA; OLFACTORY RECEPTOR NEURONS; STEM CELLS;

EID: 84884719181     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2013.07.020     Document Type: Article

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