Neurotoxic, Inflammatory, and Mucosecretory Responses in the Nasal Airways of Mice Repeatedly Exposed to the Macrocyclic Trichothecene Mycotoxin Roridin A:Dose-Response and Persistence of Injury

Toxicologic Pathology

Volumn 38, Issue 3, 2010, Pages 429-451

  Corps, Kara N ^a   Islam, Zahidul ^a,b   Pestka, James J ^a,b   Harkema, Jack R ^a  

^a MICHIGAN STATE UNIVERSITY   (United States)

^b NONE   (United States)

Author keywords

macrocyclic trichothecene mycotoxin; nasal toxicity; olfactory neurodegeneration; rhinitis; roridin A

Indexed keywords

MACROCYCLIC COMPOUND; MYCOTOXIN; RORIDIN A; TRICHOTHECENE DERIVATIVE;

ADULT ANIMAL; AIRBORNE PARTICLE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATROPHY; C57BL 6 MOUSE; CONTROLLED STUDY; DOSE RESPONSE; ENVIRONMENTAL EXPOSURE; FEMALE; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; INFLAMMATION; MORPHOMETRICS; MOUSE; MUCUS SECRETION; NERVE DEGENERATION; NEUROTOXICITY; NEUTROPHILIA; NONHUMAN; NOSE; NOSE MUCOSA; OLFACTORY NERVE; PRIORITY JOURNAL; RESPIRATORY EPITHELIUM; RHINITIS; SENSORY NERVE CELL;

ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; IMMUNOHISTOCHEMISTRY; INFLAMMATION; MACROCYCLIC COMPOUNDS; MALE; MICE; MICE, INBRED C57BL; MUCUS; MYCOTOXINS; NASAL MUCOSA; RHINITIS; SENSORY RECEPTOR CELLS; TRICHOTHECENES;

MUS;

EID: 77952533498     PISSN: 01926233     EISSN: 15331601     Source Type: Journal    
DOI: 10.1177/0192623310364026     Document Type: Article

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