Metabolic activation of 2,6-dichlorobenzonitrile, an olfactory-specific toxicant, by rat, rabbit, and human cytochromes P450

Molecular Pharmacology

Volumn 49, Issue 6, 1996, Pages 1113-1121

  Ding, Xinxin ^a   Spink, David C ^a   Bhama, Jay K ^b   Sheng, Jonathan J ^a   Vaz, Alfin D N ^b   Coon, Minor J ^b  

^a WADSWORTH CENTER   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450; DICHLOBENIL;

ARTICLE; COVALENT BOND; DNA ADDUCT; DRUG METABOLISM; ENZYME RECONSTITUTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; METABOLIC ACTIVATION; MICROSOME; NEUROEPITHELIUM; NONHUMAN; OLFACTORY EPITHELIUM; OLFACTORY TRACT; PRIORITY JOURNAL; TISSUE SPECIFICITY;

ANIMALS; BIOTRANSFORMATION; CYTOCHROME P-450 ENZYME SYSTEM; EPOXIDE HYDROLASES; GLUTATHIONE; HERBICIDES; HUMANS; MALE; MICROSOMES; NITRILES; OLFACTORY MUCOSA; RABBITS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0029982314     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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