CYP2A5-mediated activation and early ultrastructural changes in the olfactory mucosa: Studies on 2,6-dichlorophenyl methylsulfone

Drug Metabolism and Disposition

Volumn 34, Issue 1, 2006, Pages 61-68

  Franzén, Anna ^a   Carlsson, Carina ^a,b   Hermansson, Veronica ^a   Lang, Matti ^a   Brittebo, Eva B ^a  

^a UPPSALA UNIVERSITY   (Sweden)

^b MEDICAL PRODUCTS AGENCY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

2,6 DICHLOROPHENYLMETHYLSULFONE; CHLORZOXAZONE; COUMARIN; CYTOCHROME P450; CYTOCHROME P450 2A4; CYTOCHROME P450 2A5; CYTOCHROME P450 2A6; CYTOCHROME P450 2E1; CYTOCHROME P450 2G1; CYTOCHROME P450 2J; DICHLOBENIL; PYRAZOLE; SULFONE DERIVATIVE; THIOL DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOLOGICAL ACTIVITY; CELL DEATH; CELL ORGANELLE; CELL SWELLING; CONTROLLED STUDY; COVALENT BOND; ENDOPLASMIC RETICULUM; ENZYME ACTIVATION; ENZYME SUBSTRATE; FEMALE; HOMEOSTASIS; INJECTION; LIVER MICROSOME; MALE; MITOCHONDRION; MOUSE; NERVE CELL; NONHUMAN; OLFACTORY EPITHELIUM; PRIORITY JOURNAL; SECRETORY GRANULE; ULTRASTRUCTURE; WILD TYPE; YEAST CELL;

ANIMALS; ARYL HYDROCARBON HYDROXYLASES; BENZENE DERIVATIVES; CHLORZOXAZONE; COUMARINS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOPLASMIC RETICULUM; FEMALE; INJECTIONS, INTRAPERITONEAL; LIVER; METYRAPONE; MICE; MICROSCOPY, ELECTRON, TRANSMISSION; MICROSOMES, LIVER; MIXED FUNCTION OXYGENASES; NITRILES; OLFACTORY MUCOSA; PYRAZOLES; SULFHYDRYL COMPOUNDS; SULFONES;

ANIMALIA;

EID: 29944444345     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.105.006221     Document Type: Article

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