Accumulation of autophagosomes in breast cancer cells induces TRAIL resistance through downregulation of surface expression of death receptors 4 and 5

Oncotarget

Volumn 4, Issue 9, 2013, Pages 1349-1364

  Di, Xu ^a   Zhang, Guofeng ^b   Zhang, Yaqin ^a   Takeda, Kazuyo ^c   Rivera Rosado, Leslie A ^a   Zhang, Baolin ^a  

^a CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

^b NATIONAL INSTITUTE OF BIOMEDICAL IMAGING AND BIOENGINEERING   (United States)

^c CENTER FOR BIOLOGICS EVALUATION AND RESEARCH   (United States)

Author keywords

Basal autophagosomes; Cell surface expression; Death receptors; TRAIL resistance

Indexed keywords

CASPASE 3; CASPASE 8; DEATH RECEPTOR 4; DEATH RECEPTOR 5; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; BREAST CANCER; CANCER CELL; CANCER RESISTANCE; CELL DISRUPTION; CELL VIABILITY; CONTROLLED STUDY; DOWN REGULATION; ELECTRON MICROSCOPY; ENZYME ACTIVATION; FEMALE; FLUORESCENCE MICROSCOPY; GENE SILENCING; HUMAN; HUMAN CELL; IMMUNOBLOTTING; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; UPREGULATION;

ANIMALS; APOPTOSIS; AUTOPHAGY; BREAST NEOPLASMS; CELL LINE, TUMOR; DOWN-REGULATION; FEMALE; HUMANS; MCF-7 CELLS; MICE; MICE, NUDE; PHAGOSOMES; RECEPTORS, TNF-RELATED APOPTOSIS-INDUCING LIGAND; RECOMBINANT PROTEINS; TNF-RELATED APOPTOSIS-INDUCING LIGAND; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84884699189     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.1174     Document Type: Article

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