메뉴 건너뛰기




Volumn 2, Issue 5, 2011, Pages 418-421

Novel insights into the synergistic interaction of Bortezomib and TRAIL: tBid provides the link

Author keywords

Apoptosis; Cancer; Chemotherapy; Proteasome inhibitor; TRAIL

Indexed keywords

BORTEZOMIB; CASPASE 8; DEATH RECEPTOR 5; PROTEASOME; PROTEIN BID; PROTEIN NOXA; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND RECEPTOR; BORONIC ACID DERIVATIVE; PYRAZINE DERIVATIVE;

EID: 80053410931     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.277     Document Type: Article
Times cited : (14)

References (44)
  • 1
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: the next generation
    • Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell. 2011; 144: 646-674.
    • (2011) Cell , vol.144 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 2
    • 33746886979 scopus 로고    scopus 로고
    • Extrinsic versus intrinsic apoptosis pathways in anticancer chemotherapy
    • Fulda S, Debatin KM. Extrinsic versus intrinsic apoptosis pathways in anticancer chemotherapy. Oncogene. 2006; 25: 4798-4811.
    • (2006) Oncogene , vol.25 , pp. 4798-4811
    • Fulda, S.1    Debatin, K.M.2
  • 3
    • 44749085513 scopus 로고    scopus 로고
    • Targeting the extrinsic apoptosis pathway in cancer
    • Ashkenazi A. Targeting the extrinsic apoptosis pathway in cancer. Cytokine Growth Factor Rev. 2008; 19: 325-331.
    • (2008) Cytokine Growth Factor Rev , vol.19 , pp. 325-331
    • Ashkenazi, A.1
  • 4
    • 58149296552 scopus 로고    scopus 로고
    • Tumor resistance to apoptosis
    • Fulda S. Tumor resistance to apoptosis. Int J Cancer. 2009; 124: 511-515.
    • (2009) Int J Cancer , vol.124 , pp. 511-515
    • Fulda, S.1
  • 5
    • 33144469102 scopus 로고    scopus 로고
    • The proteasome and proteasome inhibitors in cancer therapy
    • Voorhees PM, Orlowski RZ. The proteasome and proteasome inhibitors in cancer therapy. Annu Rev Pharmacol Toxicol. 2006; 46: 189-213.
    • (2006) Annu Rev Pharmacol Toxicol , vol.46 , pp. 189-213
    • Voorhees, P.M.1    Orlowski, R.Z.2
  • 6
    • 80052066877 scopus 로고    scopus 로고
    • Proteotoxic stress targeted therapy (PSTT): induction of protein misfolding enhances the antitumor effect of the proteasome inhibitor bortezomib
    • Neznanov N, Komarov AP, Neznanova L, Stanhope-Baker P, Gudkov AV. Proteotoxic stress targeted therapy (PSTT): induction of protein misfolding enhances the antitumor effect of the proteasome inhibitor bortezomib. Oncotarget. 2011; 2: 209-221.
    • (2011) Oncotarget , vol.2 , pp. 209-221
    • Neznanov, N.1    Komarov, A.P.2    Neznanova, L.3    Stanhope-Baker, P.4    Gudkov, A.V.5
  • 7
    • 80053452602 scopus 로고    scopus 로고
    • Bortezomib: killing two birds with one stone in gastrointestinal stromal tumors
    • Duensing S, Duensing A. Bortezomib: killing two birds with one stone in gastrointestinal stromal tumors. Oncotarget. 2011; 1: 6-8.
    • (2011) Oncotarget , vol.1 , pp. 6-8
    • Duensing, S.1    Duensing, A.2
  • 8
    • 79955992274 scopus 로고    scopus 로고
    • Bortezomib primes neuroblastoma cells for TRAIL-induced apoptosis by linking the death receptor to the mitochondrial pathway
    • Naumann I, Kappler R, von Schweinitz D, Debatin KM, Fulda S. Bortezomib primes neuroblastoma cells for TRAIL-induced apoptosis by linking the death receptor to the mitochondrial pathway. Clin Cancer Res. 2011.
    • Clin Cancer Res. 2011.
    • Naumann, I.1    Kappler, R.2    von Schweinitz, D.3    Debatin, K.M.4    Fulda, S.5
  • 9
    • 33847328289 scopus 로고    scopus 로고
    • The Bcl-2 apoptotic switch in cancer development and therapy
    • Adams JM, Cory S. The Bcl-2 apoptotic switch in cancer development and therapy. Oncogene. 2007; 26: 1324-1337.
    • (2007) Oncogene , vol.26 , pp. 1324-1337
    • Adams, J.M.1    Cory, S.2
  • 10
    • 0034647563 scopus 로고    scopus 로고
    • Ubiquitinmediated degradation of the proapoptotic active form of bid A functional consequence on apoptosis induction
    • Breitschopf K, Zeiher AM, Dimmeler S. Ubiquitinmediated degradation of the proapoptotic active form of bid. A functional consequence on apoptosis induction. J Biol Chem. 2000; 275: 21648-21652.
    • (2000) J Biol Chem , vol.275 , pp. 21648-21652
    • Breitschopf, K.1    Zeiher, A.M.2    Dimmeler, S.3
  • 11
    • 15944387964 scopus 로고    scopus 로고
    • The proteasome inhibitor bortezomib sensitizes cells to killing by death receptor ligand TRAIL via BH3-only proteins Bik and Bim
    • Nikrad M, Johnson T, Puthalalath H, Coultas L, Adams J, Kraft AS. The proteasome inhibitor bortezomib sensitizes cells to killing by death receptor ligand TRAIL via BH3-only proteins Bik and Bim. Mol Cancer Ther. 2005; 4: 443-449.
    • (2005) Mol Cancer Ther , vol.4 , pp. 443-449
    • Nikrad, M.1    Johnson, T.2    Puthalalath, H.3    Coultas, L.4    Adams, J.5    Kraft, A.S.6
  • 13
    • 41949136647 scopus 로고    scopus 로고
    • Bortezomib blocks Bax degradation in malignant B cells during treatment with TRAIL
    • Liu FT, Agrawal SG, Gribben JG, Ye H, Du MQ, Newland AC, Jia L. Bortezomib blocks Bax degradation in malignant B cells during treatment with TRAIL. Blood. 2008; 111: 2797-2805.
    • (2008) Blood , vol.111 , pp. 2797-2805
    • Liu, F.T.1    Agrawal, S.G.2    Gribben, J.G.3    Ye, H.4    Du, M.Q.5    Newland, A.C.6    Jia, L.7
  • 15
    • 20344393387 scopus 로고    scopus 로고
    • Cooperative cytotoxicity of proteasome inhibitors and tumor necrosis factor-related apoptosis-inducing ligand in chemoresistant Bcl-2-overexpressing cells
    • Nencioni A, Wille L, Dal Bello G, Boy D, Cirmena G, Wesselborg S, Belka C, Brossart P, Patrone F, Ballestrero A. Cooperative cytotoxicity of proteasome inhibitors and tumor necrosis factor-related apoptosis-inducing ligand in chemoresistant Bcl-2-overexpressing cells. Clin Cancer Res. 2005; 11: 4259-4265.
    • (2005) Clin Cancer Res , vol.11 , pp. 4259-4265
    • Nencioni, A.1    Wille, L.2    Dal Bello, G.3    Boy, D.4    Cirmena, G.5    Wesselborg, S.6    Belka, C.7    Brossart, P.8    Patrone, F.9    Ballestrero, A.10
  • 18
    • 30144442233 scopus 로고    scopus 로고
    • The proteasome inhibitor bortezomib induces apoptosis in mantle-cell lymphoma through generation of ROS and Noxa activation independent of p53 status
    • Perez-Galan P, Roue G, Villamor N, Montserrat E, Campo E, Colomer D. The proteasome inhibitor bortezomib induces apoptosis in mantle-cell lymphoma through generation of ROS and Noxa activation independent of p53 status. Blood. 2006; 107: 257-264.
    • (2006) Blood , vol.107 , pp. 257-264
    • Perez-Galan, P.1    Roue, G.2    Villamor, N.3    Montserrat, E.4    Campo, E.5    Colomer, D.6
  • 20
    • 21344453520 scopus 로고    scopus 로고
    • Proteasome inhibitor MG132 induces death receptor 5 through CCAAT/enhancerbinding protein homologous protein
    • Yoshida T, Shiraishi T, Nakata S, Horinaka M, Wakada M, Mizutani Y, Miki T, Sakai T. Proteasome inhibitor MG132 induces death receptor 5 through CCAAT/enhancerbinding protein homologous protein. Cancer Res. 2005; 65: 5662-5667.
    • (2005) Cancer Res , vol.65 , pp. 5662-5667
    • Yoshida, T.1    Shiraishi, T.2    Nakata, S.3    Horinaka, M.4    Wakada, M.5    Mizutani, Y.6    Miki, T.7    Sakai, T.8
  • 21
    • 1942436864 scopus 로고    scopus 로고
    • Proteasome inhibitor MG132 upregulates death receptor 5 and cooperates with Apo2L/ TRAIL to induce apoptosis in Bax-proficient and -deficient cells
    • He Q, Huang Y, Sheikh MS. Proteasome inhibitor MG132 upregulates death receptor 5 and cooperates with Apo2L/ TRAIL to induce apoptosis in Bax-proficient and -deficient cells. Oncogene. 2004; 23: 2554-2558.
    • (2004) Oncogene , vol.23 , pp. 2554-2558
    • He, Q.1    Huang, Y.2    Sheikh, M.S.3
  • 22
    • 0043287140 scopus 로고    scopus 로고
    • The proteasome inhibitor PS-341 overcomes TRAIL resistance in Bax and caspase 9-negative or Bcl-xL overexpressing cells
    • Johnson TR, Stone K, Nikrad M, Yeh T, Zong W-X, Thompson CB, Nesterov A, Kraft AS. The proteasome inhibitor PS-341 overcomes TRAIL resistance in Bax and caspase 9-negative or Bcl-xL overexpressing cells. Oncogene. 2003; 22: 4953-4963.
    • (2003) Oncogene , vol.22 , pp. 4953-4963
    • Johnson, T.R.1    Stone, K.2    Nikrad, M.3    Yeh, T.4    Zong, W.-X.5    Thompson, C.B.6    Nesterov, A.7    Kraft, A.S.8
  • 23
    • 34250332128 scopus 로고    scopus 로고
    • The proteasome inhibitor PS-341 (bortezomib) upregulates DR5 expression leading to induction of apoptosis and enhancement of TRAIL-induced apoptosis despite up-regulation of c-FLIP and survivin expression in human NSCLC cells
    • Liu X, Yue P, Chen S, Hu L, Lonial S, Khuri FR, Sun S-Y. The proteasome inhibitor PS-341 (bortezomib) upregulates DR5 expression leading to induction of apoptosis and enhancement of TRAIL-induced apoptosis despite up-regulation of c-FLIP and survivin expression in human NSCLC cells. Cancer Res. 2007; 67: 4981-4988.
    • (2007) Cancer Res , vol.67 , pp. 4981-4988
    • Liu, X.1    Yue, P.2    Chen, S.3    Hu, L.4    Lonial, S.5    Khuri, F.R.6    Sun, S.-Y.7
  • 24
    • 34447294826 scopus 로고    scopus 로고
    • TRAIL therapy in non-small cell lung cancer cells: sensitization to death receptor-mediated apoptosis by proteasome inhibitor bortezomib
    • Voortman J, Resende TP, Abou El Hassan MA, Giaccone G, Kruyt FA. TRAIL therapy in non-small cell lung cancer cells: sensitization to death receptor-mediated apoptosis by proteasome inhibitor bortezomib. Mol Cancer Ther. 2007; 6: 2103-2112.
    • (2007) Mol Cancer Ther , vol.6 , pp. 2103-2112
    • Voortman, J.1    Resende, T.P.2    Abou El Hassan, M.A.3    Giaccone, G.4    Kruyt, F.A.5
  • 25
    • 41549097321 scopus 로고    scopus 로고
    • Upregulation of DR5 by proteasome inhibitors potently sensitizes glioma cells to TRAIL-induced apoptosis
    • Hetschko H, Voss V, Seifert V, Prehn JH, Kogel D. Upregulation of DR5 by proteasome inhibitors potently sensitizes glioma cells to TRAIL-induced apoptosis. FEBS J. 2008; 275: 1925-1936.
    • (2008) FEBS J , vol.275 , pp. 1925-1936
    • Hetschko, H.1    Voss, V.2    Seifert, V.3    Prehn, J.H.4    Kogel, D.5
  • 26
    • 49849089793 scopus 로고    scopus 로고
    • Proteasome inhibitor PS-341 (VELCADE) induces stabilization of the TRAIL receptor DR5 mRNA through the 3'-untranslated region
    • Kandasamy K, Kraft AS. Proteasome inhibitor PS-341 (VELCADE) induces stabilization of the TRAIL receptor DR5 mRNA through the 3'-untranslated region. Mol Cancer Ther. 2008; 7: 1091-1100.
    • (2008) Mol Cancer Ther , vol.7 , pp. 1091-1100
    • Kandasamy, K.1    Kraft, A.S.2
  • 29
    • 38949181537 scopus 로고    scopus 로고
    • Bortezomib induces caspasedependent apoptosis in Hodgkin lymphoma cell lines and is associated with reduced c-FLIP expression: a gene expression profiling study with implications for potential combination therapies
    • Zhao X, Qiu W, Kung J, Peng X, Yegappan M, Yen-Lieberman B, Hsi ED. Bortezomib induces caspasedependent apoptosis in Hodgkin lymphoma cell lines and is associated with reduced c-FLIP expression: a gene expression profiling study with implications for potential combination therapies. Leuk Res. 2008; 32: 275-285.
    • (2008) Leuk Res , vol.32 , pp. 275-285
    • Zhao, X.1    Qiu, W.2    Kung, J.3    Peng, X.4    Yegappan, M.5    Yen-Lieberman, B.6    Hsi, E.D.7
  • 30
    • 38749133727 scopus 로고    scopus 로고
    • Proteasome inhibition blocks caspase-8 degradation and sensitizes prostate cancer cells to death receptor-mediated apoptosis
    • Thorpe JA, Christian PA, Schwarze SR. Proteasome inhibition blocks caspase-8 degradation and sensitizes prostate cancer cells to death receptor-mediated apoptosis. Prostate. 2008; 68: 200-209.
    • (2008) Prostate , vol.68 , pp. 200-209
    • Thorpe, J.A.1    Christian, P.A.2    Schwarze, S.R.3
  • 37
    • 34547582308 scopus 로고    scopus 로고
    • Bortezomib inhibits angiogenesis and reduces tumor burden in a murine model of neuroblastoma
    • Hamner JB, Dickson PV, Sims TL, Zhou J, Spence Y, Ng CY, Davidoff AM. Bortezomib inhibits angiogenesis and reduces tumor burden in a murine model of neuroblastoma. Surgery. 2007; 142: 185-191.
    • (2007) Surgery , vol.142 , pp. 185-191
    • Hamner, J.B.1    Dickson, P.V.2    Sims, T.L.3    Zhou, J.4    Spence, Y.5    Ng, C.Y.6    Davidoff, A.M.7
  • 38
    • 47349102144 scopus 로고    scopus 로고
    • Effect of bortezomib on human neuroblastoma: analysis of molecular mechanisms involved in cytotoxicity
    • Combaret V, Boyault S, Iacono I, Brejon S, Rousseau R, Puisieux A. Effect of bortezomib on human neuroblastoma: analysis of molecular mechanisms involved in cytotoxicity. Mol Cancer. 2008; 7: 50.
    • (2008) Mol Cancer , vol.7 , pp. 50
    • Combaret, V.1    Boyault, S.2    Iacono, I.3    Brejon, S.4    Rousseau, R.5    Puisieux, A.6
  • 41
    • 64949154023 scopus 로고    scopus 로고
    • Effects of bortezomib on human neuroblastoma cells in vitro and in a metastatic xenograft model
    • Valentiner U, Haane C, Nehmann N, Schumacher U. Effects of bortezomib on human neuroblastoma cells in vitro and in a metastatic xenograft model. Anticancer Res. 2009; 29: 1219-1225.
    • (2009) Anticancer Res , vol.29 , pp. 1219-1225
    • Valentiner, U.1    Haane, C.2    Nehmann, N.3    Schumacher, U.4
  • 43
    • 21244475037 scopus 로고    scopus 로고
    • Phase I study of the proteasome inhibitor bortezomib in pediatric patients with refractory solid tumors: a Children's Oncology Group study (ADVL0015) [erratum appears in
    • Jan 1 J Clin Oncol. 22 2004 4804-4809
    • Blaney SM, Bernstein M, Neville K, Ginsberg J, Kitchen B, Horton T, Berg SL, Krailo M, Adamson PC. Phase I study of the proteasome inhibitor bortezomib in pediatric patients with refractory solid tumors: a Children's Oncology Group study (ADVL0015).[erratum appears in J Clin Oncol. 2005 Jan 1;23(1): 248]. J Clin Oncol. 2004; 22: 4804-4809.
    • (2005) J Clin Oncol , vol.23 , Issue.1 , pp. 248
    • Blaney, S.M.1    Bernstein, M.2    Neville, K.3    Ginsberg, J.4    Kitchen, B.5    Horton, T.6    Berg, S.L.7    Krailo, M.8    Adamson, P.C.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.