Antimicrobial Peptides Design by Evolutionary Multiobjective Optimization

PLoS Computational Biology

Volumn 9, Issue 9, 2013, Pages

  Maccari, Giuseppe ^a   Di Luca, Mariagrazia ^b   Nifosí, Riccardo ^b   Cardarelli, Francesco ^a   Signore, Giovanni ^a   Boccardi, Claudia ^a   Bifone, Angelo ^a  

^a CENTER FOR NANOTECHNOLOGY INNOVATION NEST   (Italy)

^b SCUOLA NORMALE SUPERIORE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; COMPUTATIONAL CHEMISTRY; MICROORGANISMS; MULTIOBJECTIVE OPTIMIZATION; STRUCTURAL DESIGN;

ANIMAL SPECIES; ANTIMICROBIAL PEPTIDE; CELL TYPES; EVOLUTIONARY MULTIOBJECTIVE OPTIMIZATION; MAMMAL SPECIES; NON NATURAL AMINO ACIDS; PEPTIDE DESIGN; PEPTIDE SEQUENCES; PLANT SPECIES; TISSUE TYPES;

PEPTIDES;

CECROPIN MELLITIN ALPHA HELICAL ANTIMICROBIAL HYBRID; POLYPEPTIDE ANTIBIOTIC AGENT; UNCLASSIFIED DRUG;

AB INITIO CALCULATION; ALGORITHM; ALPHA HELIX; AMINO ACID SEQUENCE; ANTIBACTERIAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG DESIGN; DRUG SYNTHESIS; EVOLUTIONARY MULTIOBJECTIVE OPTIMIZATION; MOLECULAR DYNAMICS; NONHUMAN; PHYSICAL CHEMISTRY; PROTEIN MODIFICATION; PSEUDOMONAS AERUGINOSA; QUANTITATIVE STRUCTURE ACTIVITY RELATION; STAPHYLOCOCCUS AUREUS; STATISTICAL MODEL;

ANIMALIA; MAMMALIA;

ANTI-INFECTIVE AGENTS; DRUG DESIGN; MICROSCOPY, CONFOCAL; MOLECULAR DYNAMICS SIMULATION; PEPTIDES; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84884689688     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1003212     Document Type: Article

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