Causal and Synthetic Associations of Variants in the SERPINA Gene Cluster with Alpha1-antitrypsin Serum Levels

PLoS Genetics

Volumn 9, Issue 8, 2013, Pages

  Thun, Gian Andri ^a,b   Imboden, Medea ^a,b   Ferrarotti, Ilaria ^c   Kumar, Ashish ^a,b,d   Obeidat, Ma'en ^e   Zorzetto, Michele ^c   Haun, Margot ^f   Curjuric, Ivan ^a,b   Couto Alves, Alexessander ^g   Jackson, Victoria E ^h   Albrecht, Eva ⁱ   Ried, Janina S ⁱ   Teumer, Alexander ^j   Lopez, Lorna M ^k   Huffman, Jennifer E ^k   Enroth, Stefan ^l   Bossé, Yohan ^m   Hao, Ke ⁿ   Timens, Wim ^o   Gyllensten, Ulf ^l   Polasek, Ozren ^p   Wilson, James F ^q   Rudan, Igor ^q   Hayward, Caroline ^k   Sandford, Andrew J ^e   Deary, Ian J ^k   Koch, Beate ^j   Reischl, Eva ⁱ   Schulz, Holger ⁱ   Hui, Jennie ^r,s   James, Alan L ^t,u   Rochat, Thierry ^v   Russi, Erich W ^w   Jarvelin, Marjo Riitta ^g,x,y,z   Strachan, David P ^aa   Hall, Ian P ^ab   Tobin, Martin D ^h   Dahl, Morten ^ac   Fallgaard Nielsen, Sune ^ad   Nordestgaard, Børge G ^ad   Kronenberg, Florian ^f   Luisetti, Maurizio ^c   Probst Hensch, Nicole M ^a,b   more..

^a SWISS TROPICAL AND PUBLIC HEALTH INSTITUTE   (Switzerland)

^b UNIVERSITY OF BASEL   (Switzerland)

^c UNIVERSITY OF PAVIA   (Italy)

^d UNIVERSITY OF OXFORD   (United Kingdom)

^e UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^f INNSBRUCK MEDICAL UNIVERSITY   (Austria)

^g IMPERIAL COLLEGE LONDON   (United Kingdom)

^h UNIVERSITY OF LEICESTER   (United Kingdom)

ⁱ INSTITUTE OF EPIDEMIOLOGY   (Germany)

^j UNIVERSITY MEDICINE GREIFSWALD   (Germany)

^k UNIVERSITY OF EDINBURGH   (United Kingdom)

^l UPPSALA UNIVERSITY   (Sweden)

^m LAVAL UNIVERSITY   (Canada)

ⁿ MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^o UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^p UNIVERSITY OF SPLIT   (Croatia)

^q UNIVERSITY OF EDINBURGH   (United Kingdom)

^r UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^s Busselton Population Medical Research Institute   (Australia)

^t West Australian Sleep Disorders Research Institute   (Australia)

^u UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^v GENEVA UNIVERSITY HOSPITALS   (Switzerland)

^w UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^x UNIVERSITY OF OULU   (Finland)

^y OULU UNIVERSITY HOSPITAL   (Finland)

^z NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

^aa ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

^ab QUEEN S MEDICAL CENTRE   (United Kingdom)

^ac International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health   (Denmark)

^ad GENTOFTE UNIVERSITY HOSPITAL   (Denmark)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA 1 ANTITRYPSIN;

ADULT; ARTICLE; COHORT ANALYSIS; CONTROLLED STUDY; DISEASE SEVERITY; EXON; GENE CLUSTER; GENE FREQUENCY; GENE FUNCTION; GENE LOCATION; GENE LOCUS; GENE REPLICATION; GENE SEQUENCE; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOME ANALYSIS; GENOTYPE; HUMAN; LUNG FUNCTION; MAJOR CLINICAL STUDY; PROMOTER REGION; PROTEIN BLOOD LEVEL; SERPINA1 GENE; SINGLE NUCLEOTIDE POLYMORPHISM; SMOKING;

ALPHA 1-ANTITRYPSIN; DENMARK; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; HUMANS; LUNG; MULTIGENE FAMILY; POLYMORPHISM, SINGLE NUCLEOTIDE; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE;

EID: 84884642095     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1003585     Document Type: Article

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