메뉴 건너뛰기




Volumn 33, Issue 10, 2013, Pages 868-875

α-Tocopherol, ascorbic acid, and β-carotene protect against oxidative stress but reveal no direct influence on p53 expression in rats subjected to stress

Author keywords

Tocopherol; Carotene; 8 Hydroxy 2 deoxyguanosine; Ascorbic acid; Lipid peroxides; Oxidative stress; P53 protein; Rat

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; ALPHA TOCOPHEROL; ASCORBIC ACID; BETA CAROTENE; LIPID PEROXIDE; PLACEBO; PROTEIN MDM2; PROTEIN P53;

EID: 84884590486     PISSN: 02715317     EISSN: 18790739     Source Type: Journal    
DOI: 10.1016/j.nutres.2013.07.001     Document Type: Article
Times cited : (28)

References (41)
  • 1
    • 28544439691 scopus 로고    scopus 로고
    • Carotenoid actions and their relation to health and disease
    • Krinsky N.I., Johnson E.J. Carotenoid actions and their relation to health and disease. Mol Asp Med 2005, 26:459-516.
    • (2005) Mol Asp Med , vol.26 , pp. 459-516
    • Krinsky, N.I.1    Johnson, E.J.2
  • 2
    • 49649093156 scopus 로고    scopus 로고
    • Correlates of antioxidant nutrients and oxidative DNA damage differ by race in a cross-sectional study of healthy African American and white adults
    • Watters J.L., Satia J.A., Kupper L.L. Correlates of antioxidant nutrients and oxidative DNA damage differ by race in a cross-sectional study of healthy African American and white adults. Nutr Res 2008, 28:565-576.
    • (2008) Nutr Res , vol.28 , pp. 565-576
    • Watters, J.L.1    Satia, J.A.2    Kupper, L.L.3
  • 3
    • 33847378451 scopus 로고    scopus 로고
    • Mortality in randomized trials of antioxidant supplements for primary and secondary prevention: systematic review and meta-analysis
    • Bjelakovič G., Nikolova D., Gluud L.L., Simonetti R.G., Gluud C. Mortality in randomized trials of antioxidant supplements for primary and secondary prevention: systematic review and meta-analysis. JAMA 2007, 297:842-857.
    • (2007) JAMA , vol.297 , pp. 842-857
    • Bjelakovič, G.1    Nikolova, D.2    Gluud, L.L.3    Simonetti, R.G.4    Gluud, C.5
  • 4
    • 84861927005 scopus 로고    scopus 로고
    • Antioxidant supplements for prevention of mortality in healthy participants and patients with various diseases
    • CD007176
    • Bjelakovič G., Nikolova D., Gluud L.L., Simonetti R.G., Gluud C. Antioxidant supplements for prevention of mortality in healthy participants and patients with various diseases. Cochrane Database Syst Rev 2012, 3. CD007176. 10.1002/14651858.CD007176.pub2.
    • (2012) Cochrane Database Syst Rev , vol.3
    • Bjelakovič, G.1    Nikolova, D.2    Gluud, L.L.3    Simonetti, R.G.4    Gluud, C.5
  • 5
    • 4344570628 scopus 로고    scopus 로고
    • β-Carotene exacerbates DNA oxidative damage and modifies p53-related pathways of cell proliferation and apoptosis in cultured cells exposed to tobacco smoke condensate
    • Palozza P., Serini S., Di Nicuolo F., Boninsegna A., Torsello A., Maggiano N., et al. β-Carotene exacerbates DNA oxidative damage and modifies p53-related pathways of cell proliferation and apoptosis in cultured cells exposed to tobacco smoke condensate. Carcinogenesis 2004, 25:1315-1325.
    • (2004) Carcinogenesis , vol.25 , pp. 1315-1325
    • Palozza, P.1    Serini, S.2    Di Nicuolo, F.3    Boninsegna, A.4    Torsello, A.5    Maggiano, N.6
  • 7
    • 34249915541 scopus 로고    scopus 로고
    • Molecular mechanism of alpha-tocopherol action
    • Azzi A. Molecular mechanism of alpha-tocopherol action. Free Radic Biol Med 2007, 43(1):16-21.
    • (2007) Free Radic Biol Med , vol.43 , Issue.1 , pp. 16-21
    • Azzi, A.1
  • 8
    • 13144307108 scopus 로고    scopus 로고
    • Chemistry and biology of vitamin E
    • Schneider C. Chemistry and biology of vitamin E. Mol Nutr Food Res 2005, 49:7-30.
    • (2005) Mol Nutr Food Res , vol.49 , pp. 7-30
    • Schneider, C.1
  • 9
    • 84886373356 scopus 로고    scopus 로고
    • Vitamin E supplementation attenuates strenuous exercise induced DNA damage and lipid peroxidation of the liver in rats
    • Kinoshita S., Tsuji E. Vitamin E supplementation attenuates strenuous exercise induced DNA damage and lipid peroxidation of the liver in rats. Kawasaki J Med Welfare 2008, 14:1-7.
    • (2008) Kawasaki J Med Welfare , vol.14 , pp. 1-7
    • Kinoshita, S.1    Tsuji, E.2
  • 10
    • 52949097984 scopus 로고    scopus 로고
    • Effects of dietary vitamin E, C and soybean oil supplementation on antioxidant enzyme activities in liver and muscles of rats
    • Shireen K.F., Pace R.D., Mahboob M., Khan A.T. Effects of dietary vitamin E, C and soybean oil supplementation on antioxidant enzyme activities in liver and muscles of rats. Food Chem Toxicol 2008, 46:3290-3294.
    • (2008) Food Chem Toxicol , vol.46 , pp. 3290-3294
    • Shireen, K.F.1    Pace, R.D.2    Mahboob, M.3    Khan, A.T.4
  • 11
    • 0030912476 scopus 로고    scopus 로고
    • Components of the AIN-93 diets as improvements in the AIN-76A diet
    • Reeves P.G. Components of the AIN-93 diets as improvements in the AIN-76A diet. J Nutr 1997, 127(Suppl 5):S838-S841.
    • (1997) J Nutr , vol.127 , Issue.SUPPL 5
    • Reeves, P.G.1
  • 12
    • 0022388988 scopus 로고
    • Requirement for ascorbic acid in a rat mutant unable to synthesize ascorbic acid
    • Horio F., Ozaki K., Yoshida A., Makino S., Hayashi Y. Requirement for ascorbic acid in a rat mutant unable to synthesize ascorbic acid. J Nutr 1985, 115:1630-1640.
    • (1985) J Nutr , vol.115 , pp. 1630-1640
    • Horio, F.1    Ozaki, K.2    Yoshida, A.3    Makino, S.4    Hayashi, Y.5
  • 14
    • 50349087581 scopus 로고    scopus 로고
    • Effect of a diet supplemented with alpha-tocopherol and beta-carotene on ATP and antioxidant levels after hepatic ischemia-reperfusion
    • Codoñer-Franch P., Muñiz P., Gasco E., Domingo J.V., Valls-Belles V. Effect of a diet supplemented with alpha-tocopherol and beta-carotene on ATP and antioxidant levels after hepatic ischemia-reperfusion. J Clin Biochem Nutr 2008, 43:13-18.
    • (2008) J Clin Biochem Nutr , vol.43 , pp. 13-18
    • Codoñer-Franch, P.1    Muñiz, P.2    Gasco, E.3    Domingo, J.V.4    Valls-Belles, V.5
  • 15
    • 74049106642 scopus 로고    scopus 로고
    • Comparative effects of beta-carotene and fucoxanthin on retinol deficiency induced oxidative stress in rats
    • Sangeetha R.K., Bhaskar N., Baskaran V. Comparative effects of beta-carotene and fucoxanthin on retinol deficiency induced oxidative stress in rats. Mol Cell Biochem 2009, 331:59-67.
    • (2009) Mol Cell Biochem , vol.331 , pp. 59-67
    • Sangeetha, R.K.1    Bhaskar, N.2    Baskaran, V.3
  • 16
    • 69949169181 scopus 로고    scopus 로고
    • Tocopherol acetate vs oxidative stress induced by physical exercise in rats
    • Gronowska-Senger A., Górnicka M., Kołodziejska K. Tocopherol acetate vs oxidative stress induced by physical exercise in rats. Pol J Food Nutr Sci 2009, 59:263-269.
    • (2009) Pol J Food Nutr Sci , vol.59 , pp. 263-269
    • Gronowska-Senger, A.1    Górnicka, M.2    Kołodziejska, K.3
  • 17
    • 79952041472 scopus 로고    scopus 로고
    • Exercise training attenuated oxidative stress and decreased p53 protein content in skeletal muscle of type 2 diabetic Goto-kakizaki rats
    • Qi Z., He J., Zhang Y., Shao Y., Ding S. Exercise training attenuated oxidative stress and decreased p53 protein content in skeletal muscle of type 2 diabetic Goto-kakizaki rats. Free Radic Biol Med 2011, 50:794-800.
    • (2011) Free Radic Biol Med , vol.50 , pp. 794-800
    • Qi, Z.1    He, J.2    Zhang, Y.3    Shao, Y.4    Ding, S.5
  • 18
    • 0017872475 scopus 로고
    • Microsomal lipid peroxidation
    • Buege J.A., Aust S.D. Microsomal lipid peroxidation. Method Enzymol 1978, 52:302-310.
    • (1978) Method Enzymol , vol.52 , pp. 302-310
    • Buege, J.A.1    Aust, S.D.2
  • 19
    • 33845463801 scopus 로고    scopus 로고
    • Higherleukocyte 8-oxo-7,8-dihydro-2'-deoxyguanosine and lower plasma ascorbate in aging humans?
    • Siomek A., Gackowski D., Rozalski R., Dziaman T., Szpila A., Guz J., et al. Higherleukocyte 8-oxo-7,8-dihydro-2'-deoxyguanosine and lower plasma ascorbate in aging humans?. Antioxid Redox Signal 2007, 9:143-150.
    • (2007) Antioxid Redox Signal , vol.9 , pp. 143-150
    • Siomek, A.1    Gackowski, D.2    Rozalski, R.3    Dziaman, T.4    Szpila, A.5    Guz, J.6
  • 20
    • 77957847517 scopus 로고    scopus 로고
    • Vitamin E and C supplementation reduces oxidative stress, improves antioxidant enzymes and positive muscle work in chronically loaded muscles of aged rats
    • Ryan M.J., Dudash H.J., Docherty M., Geronilla K.B., Baker B.A., Haff G.G., et al. Vitamin E and C supplementation reduces oxidative stress, improves antioxidant enzymes and positive muscle work in chronically loaded muscles of aged rats. Exp Gerontol 2010, 45:882-895.
    • (2010) Exp Gerontol , vol.45 , pp. 882-895
    • Ryan, M.J.1    Dudash, H.J.2    Docherty, M.3    Geronilla, K.B.4    Baker, B.A.5    Haff, G.G.6
  • 21
    • 80051668513 scopus 로고    scopus 로고
    • Vitamins C and E beneficial effects from a mechanistic perspective
    • Traber M.G., Stevens J.F. Vitamins C and E beneficial effects from a mechanistic perspective. Free Radic Biol Med 2011, 51:1000-1013.
    • (2011) Free Radic Biol Med , vol.51 , pp. 1000-1013
    • Traber, M.G.1    Stevens, J.F.2
  • 22
    • 4344648152 scopus 로고    scopus 로고
    • Biomarkers of antioxidant capacity in the hydrophilic and lipophilic compartments of human plasma
    • Yeum K.J., Russell R.M., Krinsky N.I., Aldini G. Biomarkers of antioxidant capacity in the hydrophilic and lipophilic compartments of human plasma. Arch Biochem Biophys 2004, 430:97-103.
    • (2004) Arch Biochem Biophys , vol.430 , pp. 97-103
    • Yeum, K.J.1    Russell, R.M.2    Krinsky, N.I.3    Aldini, G.4
  • 23
    • 0003543976 scopus 로고    scopus 로고
    • The white book on antioxidants in tomatoes and tomato products and their health benefits
    • Final Report of the Concerted Action FAIR CT97-3233
    • Bilton R, Gerber M, Grolier P, Leoni C. The white book on antioxidants in tomatoes and tomato products and their health benefits. Final Report of the Concerted Action FAIR CT97-3233; 2001.
    • (2001)
    • Bilton, R.1    Gerber, M.2    Grolier, P.3    Leoni, C.4
  • 24
    • 20944444718 scopus 로고    scopus 로고
    • DNA stability and lipid peroxidation in vitamin E-deficient rats in vivo and colon cells in vitro
    • Duthie S.J., Gardner P.T., Morrice P.C., Wood S.G., Pirie L., Bestwick C.C., et al. DNA stability and lipid peroxidation in vitamin E-deficient rats in vivo and colon cells in vitro. Eur J Nutr 2005, 44:195-203.
    • (2005) Eur J Nutr , vol.44 , pp. 195-203
    • Duthie, S.J.1    Gardner, P.T.2    Morrice, P.C.3    Wood, S.G.4    Pirie, L.5    Bestwick, C.C.6
  • 25
    • 0029002501 scopus 로고
    • The integrated antioxidant system
    • Jacob R.A. The integrated antioxidant system. Nutr Res 1995, 15:755-766.
    • (1995) Nutr Res , vol.15 , pp. 755-766
    • Jacob, R.A.1
  • 26
    • 0842324549 scopus 로고    scopus 로고
    • Antioxidant potential of vitamins A, E and C in modulating oxidative stress in rat brain
    • Zaidi K.R., Banu N. Antioxidant potential of vitamins A, E and C in modulating oxidative stress in rat brain. Clin Chim Acta 2004, 340:229-233.
    • (2004) Clin Chim Acta , vol.340 , pp. 229-233
    • Zaidi, K.R.1    Banu, N.2
  • 27
    • 27544492751 scopus 로고    scopus 로고
    • Lipid peroxidation: mechanisms, inhibition, and biological effects
    • Niki E., Yoshida Y., Saito Y., Noguchi N. Lipid peroxidation: mechanisms, inhibition, and biological effects. Biochem Biophys Res Commun 2005, 338:668-676.
    • (2005) Biochem Biophys Res Commun , vol.338 , pp. 668-676
    • Niki, E.1    Yoshida, Y.2    Saito, Y.3    Noguchi, N.4
  • 28
    • 21244464231 scopus 로고    scopus 로고
    • Oxidative DNA, modifications
    • Poulsen H.E. Oxidative DNA, modifications. Exp Toxicol Pathol 2005, 57:161-169.
    • (2005) Exp Toxicol Pathol , vol.57 , pp. 161-169
    • Poulsen, H.E.1
  • 29
    • 77958181129 scopus 로고    scopus 로고
    • Oxidative DNA damage-analysis and clinical significance
    • Zaremba T., Oliński R. Oxidative DNA damage-analysis and clinical significance. Post Biochem 2010, 56:124-138.
    • (2010) Post Biochem , vol.56 , pp. 124-138
    • Zaremba, T.1    Oliński, R.2
  • 30
  • 31
  • 32
    • 43149108399 scopus 로고    scopus 로고
    • Antioxidant vitamins and cancer risk is oxidative damage to DNA a relevant biomarker?
    • Loft S., Möller P., Cooke M.S., Rozalski R., Olinski R. Antioxidant vitamins and cancer risk is oxidative damage to DNA a relevant biomarker?. Eur J Nutr 2008, 47(Suppl. 2):S19-S28.
    • (2008) Eur J Nutr , vol.47 , Issue.SUPPL. 2
    • Loft, S.1    Möller, P.2    Cooke, M.S.3    Rozalski, R.4    Olinski, R.5
  • 34
    • 33745898848 scopus 로고    scopus 로고
    • Dietary antioxidants and beneficial effect on oxidatively damaged DNA
    • Möller P., Loft S. Dietary antioxidants and beneficial effect on oxidatively damaged DNA. Free Radic Biol Med 2006, 41:388-415.
    • (2006) Free Radic Biol Med , vol.41 , pp. 388-415
    • Möller, P.1    Loft, S.2
  • 35
    • 60849119548 scopus 로고    scopus 로고
    • Acute exercise and oxidative stress. A 30 year history
    • Fisher-Wellman K., Bloomer R.J. Acute exercise and oxidative stress. A 30 year history. Dyn Med 2009, 8:1.
    • (2009) Dyn Med , vol.8 , pp. 1
    • Fisher-Wellman, K.1    Bloomer, R.J.2
  • 36
    • 18244368995 scopus 로고    scopus 로고
    • The effects of moderate, strenuous, and overtraining on oxidative stress markers and DNA repair in rat liver
    • Ogonovszky H., Savari M., Dosek A., Berkes I., Kaneko T., Tahara S., et al. The effects of moderate, strenuous, and overtraining on oxidative stress markers and DNA repair in rat liver. Can J App Physiol 2005, 30:186-195.
    • (2005) Can J App Physiol , vol.30 , pp. 186-195
    • Ogonovszky, H.1    Savari, M.2    Dosek, A.3    Berkes, I.4    Kaneko, T.5    Tahara, S.6
  • 37
    • 37849004479 scopus 로고    scopus 로고
    • Systemic adaptation to oxidative challenge induced by regular exercise
    • Radak Z., Chung H.Y., Goto S. Systemic adaptation to oxidative challenge induced by regular exercise. Free Radic Biol Med 2008, 44:153-159.
    • (2008) Free Radic Biol Med , vol.44 , pp. 153-159
    • Radak, Z.1    Chung, H.Y.2    Goto, S.3
  • 38
    • 0037473049 scopus 로고    scopus 로고
    • Apoptosis or growth arrest modulation of the cellular response to p53 by proliferative signals
    • Heinrichs S., Deppert W. Apoptosis or growth arrest modulation of the cellular response to p53 by proliferative signals. Oncogene 2003, 22:555-571.
    • (2003) Oncogene , vol.22 , pp. 555-571
    • Heinrichs, S.1    Deppert, W.2
  • 40
    • 0036247821 scopus 로고    scopus 로고
    • P53-Mdm2-the affair that never ends
    • Alarcon-Vargas D., Ronai Z. p53-Mdm2-the affair that never ends. Carcinogenesis 2002, 23:541-547.
    • (2002) Carcinogenesis , vol.23 , pp. 541-547
    • Alarcon-Vargas, D.1    Ronai, Z.2
  • 41
    • 0038075338 scopus 로고    scopus 로고
    • Decision making by p53 life, death and cancer
    • Oren M. Decision making by p53 life, death and cancer. Cell Death Differ 2003, 10:431-442.
    • (2003) Cell Death Differ , vol.10 , pp. 431-442
    • Oren, M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.