Lycopene and β-carotene protect in vivo iron-induced oxidative stress damage in rat prostate

Brazilian Journal of Medical and Biological Research

Volumn 39, Issue 2, 2006, Pages 203-210

  Matos, H R ^b   Marques, S A ^a   Gomes, O F ^a   Silva, A A ^a   Heimann, J C ^a   Di Mascio, P ^a   Medeiros, M H G ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b FEDERAL UNIVERSITY OF SERGIPE   (Brazil)

Author keywords

8 oxo 7,8 dihydro 2 deoxyguanosine; DNA damage; Ferric nitrilotriacetate; Lycopene; Prostate cancer; carotene

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; BETA CAROTENE; DNA; LYCOPENE; MALONALDEHYDE; NITRILOTRIACETATE IRON;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BLOOD SAMPLING; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DNA DAMAGE; DNA EXTRACTION; DRUG BLOOD LEVEL; ELECTROCHEMICAL DETECTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VIVO STUDY; IRON OVERLOAD; LIPID PEROXIDATION; MALE; NONHUMAN; OXIDATIVE STRESS; PROSTATE CANCER; RAT; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE;

ANIMALIA; LYCOPERSICON ESCULENTUM; RATTUS NORVEGICUS;

EID: 33646200322     PISSN: 0100879X     EISSN: 1414431X     Source Type: Journal    
DOI: 10.1590/S0100-879X2006000200006     Document Type: Article

References (39)

1. Ames BN, Gold LS & Willett WC (1995). The causes and prevention of cancer. Proceedings of the National Academy of Sciences, USA, 995: 5258-5265.
2. Giovannucci E (1999). Tomatoes, tomato-based products, lycopene, and cancer: Review of the epidemiologic literature. Journal of the National Cancer Institute, 91: 317-331.
3. Stahl W & Sies H (1996). Lycopene: A biologically important carotenoid for humans? Archives of Biochemistry and Biophysics, 336: 1-9.
4. Kiokias S & Gordon MH (2004). Antioxidant properties of carotenoids in vitro and in vivo. Food Reviews International, 20: 99-121.
5. Kennedy TA & Lieber DC (1992). Peroxyl radical scavenging by beta-carotene in lipid bilayers - effect of oxygen partial-pressure. Journal of Biological Chemistry, 267: 4658-4663.
6. Palozza P, Moualla S & Krinsky NI (1992). Effects of beta-carotene and apha-tocopherol on radical-initiated peroxidation of microsomes. Free Radical Biology and Medicine, 13: 127-136.
7. Terao J (1989). Antioxidant activity of beta-carotene-related carotenoids in solution. Lipids, 24: 659-661.
8. Di Mascio P, Kaiser S & Sies H (1989). Lycopene as the most efficient biological carotenoid singlet oxygen quencher. Archives of Biochemistry and Biophysics, 274: 532-538.
9. Rao AV & Agarwal S (2000). Role of antioxidant lycopene in cancer and heart disease. Journal of the American College of Nutrition, 19: 563-569.
10. Stahl W, von Laar J, Martin H-D et al. (2000). Stimulation of gap junctional communication: Comparison of acyclo-retinoic acid and lycopene. Archives of Biochemistry and Biophysics, 373: 271-274.
11. Meneghini R (1997). Iron homeostasis, oxidative stress, and DNA damage. Free Radical Biology and Medicine, 23: 783-792.
12. Dreher D & Junod AF (1996). Role of oxygen free radicals in cancer development. European Journal of Cancer, 32: 30-38.
13. Ames BN (1983). Dietary carcinogens and anticarcinogens-oxygen radicals and degenerative diseases. Science, 221: 1256-1264.
14. Valko M, Morris H & Cronin MTD (2005). Metals, toxicity and oxidative stress. Current Medicinal Chemistry 12: 1161-1208.
15. Stohs SJ & Bagchi D (1995). Oxidative mechanisms in the toxicity of metal ions. Free Radical Biology and Medicine, 18: 321-336.
16. Chapoutot C, Esslimani M, Joomaye Z et al. (2000). Liver iron excess in patients with hepatocellular carcinoma developed on viral C cirrhosis. Gut, 46: 711-714.
17. Toyokuni S (1996). Iron-induced carcinogenesis: The role of redox regulation. Free Radical Biology and Medicine, 20: 553-556.
18. Suzumura K, Hashimura Y, Kubota H et al. (2000). Antioxidative property of T-0970, a new ureidophenol derivative. Free Radical Biology and Medicine, 32: 255-264.
19. Ebina Y, Okada S, Hamazaki S et al. (1986). Nephrotoxicity and renal cell carcinoma after use of iron- and aluminum-nitrilotriacetate complexes in rats. Journal of the National Cancer Institute, 76: 107-113.
20. Umemura T, Sai K, Takagi A et al. (1990). Formation of 8-hydroxy-deoxyguanosine (8-OH-dG) in rat kidney DNA after intraperitoneal administration of ferric nitrilotriacetate (Fe-NTA). Carcinogenesis, 11: 345-347.
21. Yamaguchi R, Hirano T, Asami S et al. (1996). Increased 8-hydroxyguanine levels in DNA and its repair activity in rat kidney after administration of a renal carcinogen, ferric nitrilotriacetate. Carcinogenesis, 17: 2419-2422.
22. Toyokuni S, Mori T & Dizdaroglu M (1994). DNA base modifications in renal chromatin of Wistar rats treated with a renal carcinogen, ferric nitrilotriacetate. International Journal of Cancer, 57: 123-128.
23. Kawanishi S, Hiraku Y, Murata M et al. (2002). The role of metals in site-specific DNA damage with reference to carcinogenesis. Free Radical Biology and Medicine, 32: 822-832.
24. Matos H R, Di Mascio P & Medeiros MHG (2000). Protective effect of lycopene on lipid peroxidation and oxidative DNA damage in cell culture. Archives of Biochemistry and Biophysics, 383: 56-59.
25. Matos HR, Capelozzi VL, Gomes OF et al. (2001). Lycopene inhibits DNA damage and liver necrosis in rats treated with ferric nitrilotriacetate. Archives of Biochemistry and Biophysics, 396: 171-177.
26. Boileau TWM, Liao ZM, Kim S et al. (2003). Prostate carcinogenesis in N-methyl-N-nitrosourea (NMU)-testosterone-treated rats fed tomato powder, lycopene, or energy-restricted diets. Journal of the National Cancer Institute, 95: 1578-1586.
27. Aust O, Ale-Agha N, Zhang L et al. (2003). Lycopene oxidation product enhances gap junctional communication. Food and Chemical Toxicology, 41: 1399-1407.
28. Bates GW & Schlabach MR (1973). The reaction of ferric salts with transferrin. Journal of Biological Chemistry, 248: 3228-3232.
29. Forssberg A, Lingen C, Ernst L et al. (1959). Modification of the X-irradiation syndrome by lycopene. Experimental Cell Research, 16: 7-14.
30. Riso P, Pinder A, Santangelo A et al. (1999). Does tomato consumption effectively increase the resistance of lymphocyte DNA to oxidative damage? American Journal of Clinical Nutrition, 69: 712-718.
31. Lowe GM, Booth LA, Young AJ et al. (1999). Lycopene and β-carotene protect against oxidative damage in HT29 cells at low concentrations but rapidly lose this capacity at higher doses. Free Radical Research, 30: 141-151.
32. Zhao Z, Khachik F, Richie JP et al. (1998). Lycopene uptake and tissue disposition in male and female rats. Proceedings of the Society for Experimental Biology and Medicine, 218: 109-114.
33. Wang L, Hirayasu K, Ishizawa M et al. (1994). Purification of genomic DNA from human whole blood by isopropanol-fractionation with concentrated Nal and SDS. Nucleic Acids Research, 22: 1774-1775.
34. Esterbauer H & Cheeseman KH (1990). Determination of aldehydic lipid peroxidation products: malondialdehyde and 4-hydroxynonenal. Methods in Enzymology, 186: 407-421.
35. Willkox JK, Ash SL & Catignani GL (2004). Antioxidants and prevention of chronic disease. Critical Reviews in Food Science and Nutrition, 44: 275-295.
36. Chen L, Stacewicz-Sapuntzakis M, Duncan C et al. (2001). Oxidative DNA damage in prostate cancer patients consuming tomato sauce-based entrees as a whole-food intervention. Journal of the National Cancer Institute, 93: 1872-1879.
37. Higinbotham KG, Rice JM, Diwan BA et al. (1992). GGT to GTT transversions in codon 12 of the K-ras oncogene in rat renal sarcomas induced with nickel subsulfide or nickel subsulfide/iron are consistent with oxidative damage to DNA. Cancer Research, 52: 4747-4751.
38. Halliwell B (1999). Oxygen and nitrogen are pro-carcinogens, damage to DNA by reactive oxygen, chlorine and nitrogen species: measurement, mechanism and the effects of nutrition. Mutation Research - Genetic Toxicology and Environmental Mutagenesis, 443: 37-52.
39. Malins DC, Johnson PM, Barker EA et al. (2003). Cancer-related changes in prostate DNA as men age and early identification of metastasis in primary prostate tumors. Proceedings of the National Academy of Sciences, USA, 100: 5401-5406.