Effects of basal level of antioxidants on oxidative DNA damage in humans

European Journal of Nutrition

Volumn 46, Issue 3, 2007, Pages 174-180

  Foksinski, Marek ^a   Gackowski, Daniel ^a   Rozalski, Rafal ^a   Siomek, Agnieszka ^a   Guz, Jolanta ^a   Szpila, Anna ^a   Dziaman, Tomasz ^a   Olinski, Ryszard ^a  

^a NICOLAUS COPERNICUS UNIVERSITY   (Poland)

Author keywords

Antioxidant vitamins; DNA repair; Oxidative DNA damage

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; ALPHA TOCOPHEROL; ANTIOXIDANT; ASCORBIC ACID; DNA; RETINOL; URIC ACID;

ADULT; AGED; ANTIOXIDANT ACTIVITY; ARTICLE; CANCER INHIBITION; DNA DAMAGE; FEMALE; GAS CHROMATOGRAPHY; HUMAN; LEUKOCYTE; MALE; MASS SPECTROMETRY; NORMAL HUMAN; OXIDATIVE STRESS; PURIFICATION;

ADULT; AGED; AGED, 80 AND OVER; ANTIOXIDANTS; BIOLOGICAL MARKERS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DEOXYGUANOSINE; DNA DAMAGE; FEMALE; FREE RADICAL SCAVENGERS; GUANINE; HUMANS; LEUKOCYTES; MALE; MIDDLE AGED; NEOPLASMS; OXIDATION-REDUCTION; OXIDATIVE STRESS; URIC ACID; VITAMINS;

EID: 33947598528     PISSN: 14366207     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00394-006-0642-7     Document Type: Article

References (19)

1. Block G, Patterson B, Subar A (1992) Fruit, vegetables, and cancer prevention: a review of the epidemiological evidence. Nutr Cancer 18:1-29
2. ESCODD (2002) Inter-laboratory validation of procedures for measuring 8-oxo-7,8-dihydroguanine/8-oxo-7,8-dihydro-2′-deoxyguanosine in DNA. Free Radic Res 36:239-245
3. Cooke MS, Evans MD, Dove R, Rozalski R, Gackowski D, Siomek A, Lunec J, Olinski R (2005) DNA repair is responsible for the presence of oxidatively damaged DNA lesions in urine. Mutat Res 574:58-66
4. Ravanat JL, Guicherd P, Tuce Z, Cadet J (1999) Simultaneous determination of five oxidative DNA lesions in human urine. Chem Res Toxicol 12:802-808
5. McCall MR, Frei B (1999) Can antioxidant vitamins materially reduce oxidative damage in humans? Free Radic Biol Med 26:1034-1053
6. Moller P, Loft S (2002) Oxidative DNA damage in human white blood cells in dietary antioxidant intervention studies. Am J Clin Nutr 76:303-310
7. Rozalski R, Siomek A, Gackowski D, Foksinski M, Gran C, Klungland A, Olinski R (2004) Diet is not responsible for the presence of several oxidatively damaged DNA lesions in mouse urine. Free Radic Res 38:1201-1205
8. Gackowski D, Kruszewski M, Jawien A, Ciecierski M, Olinski R (2001) Further evidence that oxidative stress may be a risk factor responsible for the development of atherosclerosis. Free Radic Biol Med 31:542-547
9. Foksinski M, Bialkowski K, Skiba M, Ponikowska I, Szmurlo W, Olinski R (1999) Evaluation of 8-oxodeoxyguanosine, typical oxidative DNA damage, in lymphocytes of ozone-treated arteriosclerotic patients. Mutat Res 438:23-27
10. Olinski R, Gackowski D, Foksinski M, Rozalski R, Roszkowski K, Jaruga P (2002) Oxidative DNA damage: assessment of the role in carcinogenesis, atherosclerosis, and acquired immunodeficiency syndrome. Free Radic Biol Med 33:192-200
11. Olinski R, Gackowski D, Rozalski R, Foksinski M, Bialkowski K (2003) Oxidative DNA damage in cancer patients: a cause or a consequence of the disease development? Mutat Res 531:177-190
12. Jaruga P, Jaruga B, Gackowski D, Olczak A, Halota W, Pawlowska M, Olinski R (2002) Supplementation with antioxidant vitamins prevents oxidative modification of DNA in lymphocytes of HIV-infected patients. Free Radic Biol Med 32:414-420
13. Rumsey SC, Kwon O, Xu GW, Burant CF, Simpson I, Levine M (1997) Glucose transporter isoforms GLUT1 and GLUT3 transport dehydroascorbic acid. J Biol Chem 272:18982-18989
14. van den Berg H, van Vliet T (1998) Effect of simultaneous, single oral doses of beta-carotene with lutein or lycopene on the beta-carotene and retinyl ester responses in the triacylglycerol-rich lipoprotein fraction of men. Am J Clin Nutr 68:82-89
15. Enomoto A, Endou H (2005) Roles of organic anion transporters (OATs) and a urate transporter (URAT1) in the pathophysiology of human disease. Clin Exp Nephrol 9:195-205
16. Ahlemeyer B, Bauerbach E, Plath M, Steuber M, Heers C, Tegtmeier F, Krieglstein J (2001) Retinoic acid reduces apoptosis and oxidative stress by preservation of SOD protein level. Free Radic Biol Med 30:1067-1077
17. Collins AR, Olmedilla B, Southon S, Granado F, Duthie SJ (1998) Serum carotenoids and oxidative DNA damage in human lymphocytes. Carcinogenesis 19:2159-2162
18. Moller P, Loft S (2006) Dietary antioxidants and beneficial effect on oxidatively damaged DNA. Free Radic Biol Med 41:388-415
19. Phillips DH (2002) Smoking-related DNA and protein adducts in human tissues. Carcinogenesis 23:1979-2004