Fibrillar seeds alleviate amyloid-β cytotoxicity by omitting formation of higher-molecular-weight oligomers

Biochemical and Biophysical Research Communications

Volumn 439, Issue 3, 2013, Pages 321-326

  Wu, Wei hui ^a,b   Liu, Qian ^a   Sun, Xun ^a   Yu, Ji sheng ^a   Zhao, De sheng ^a   Yu, Ye ping ^a   Luo, Jun jie ^a   Hu, Jia ^a   Yu, Zhi wu ^a   Zhao, Yu fen ^a   Li, Yan mei ^a  

^a TSINGHUA UNIVERSITY   (China)

^b RESEARCH INSTITUTE OF CHEMICAL DEFENSE   (China)

Author keywords

amyloid; Aggregation; Alzheimer's disease; Fibril; Monomer; Oligomer

Indexed keywords

AMYLOID; AMYLOID BETA PROTEIN; FIBRILLAR SEED; HIGH MOLECULAR WEIGHT OLIGOMER; MONOMER; OLIGOMER; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DRUG CYTOTOXICITY; MOLECULAR INTERACTION; MOUSE; NONHUMAN; OLIGOMERIZATION; PRIORITY JOURNAL; STOICHIOMETRY; THERMODYNAMICS;

Β-AMYLOID; 3-(4,5-DIMETHYL-2-THIAZOYL)-2,5-DIPHENYLTETRAZOLIUMBROMIDE; AΒ; AD; AGGREGATION; ALZHEIMER'S DISEASE; DIMETHYL SULFOXIDE; DMEM; DMSO; DULBECCO'S MODIFIED EAGLE'S MEDIUM; FBS; FETAL BOVINE SERUM; FIBRIL; FOURIER TRANSFORM INFRARED SPECTROSCOPY; FTIR; ISOTHERMAL TITRATION CALORIMETRY; ITC; MEM; MINIMUM ESSENTIAL MEDIA; MONOMER; MTT; OLIGOMER; PBS; PHOSPHATE BUFFERED SALINE; SDS-PAGE; SEC; SIZE EXCLUSION CHROMATOGRAPHY; SODIUM DODECYL SULFATE POLYACRYLAMIDE GEL ELECTROPHORESIS; TEM; THIOFLAVIN T; THT; TRANSMISSION ELECTRON MICROSCOPE;

ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; ANIMALS; CELL LINE; CELL SURVIVAL; HUMANS; NEURONS; SOLUBILITY;

EID: 84884587118     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2013.08.088     Document Type: Article

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