Restoration of SMN to Emx-1 expressing cortical neurons is not sufficient to provide benefit to a severe mouse model of Spinal Muscular Atrophy

Transgenic Research

Volumn 22, Issue 5, 2013, Pages 1029-1036

  Taylor, Alexander S ^a   Glascock, Jacqueline J ^a,b   Rose Jr , Ferrill F ^a,b   Lutz, Cathleen ^c   Lorson, Christian L ^a,b  

^a UNIVERSITY OF MISSOURI   (United States)

^b University of Missouri   (United States)

^c JACKSON LABORATORY   (United States)

Author keywords

Animal models of disease; Central nervous system; EMX 1; Neurodegeneration; Spinal Muscular Atrophy (SMA); Survival Motor Neuron (SMN)

Indexed keywords

ANIMALIA; MUS;

EMPTY SPIRACLES HOMEOBOX PROTEINS; HOMEODOMAIN PROTEIN; SMN2 PROTEIN, HUMAN; SURVIVAL MOTOR NEURON PROTEIN 1; SURVIVAL MOTOR NEURON PROTEIN 2; TRANSCRIPTION FACTOR;

ANIMAL; ARTICLE; DISEASE MODEL; GENE TRANSFER; GENETICS; GENOTYPE; HUMAN; METABOLISM; MOTONEURON; MOUSE; SPINAL MUSCULAR ATROPHY; TRANSGENE; TRANSGENIC MOUSE; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; DISEASE MODELS, ANIMAL; GENE TRANSFER TECHNIQUES; GENOTYPE; HOMEODOMAIN PROTEINS; HUMANS; MICE; MICE, TRANSGENIC; MOTOR NEURONS; MUSCULAR ATROPHY, SPINAL; SURVIVAL OF MOTOR NEURON 1 PROTEIN; SURVIVAL OF MOTOR NEURON 2 PROTEIN; TRANSCRIPTION FACTORS; TRANSGENES;

EID: 84884586357     PISSN: 09628819     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11248-013-9702-y     Document Type: Article

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