A mouse model of limbal stem cell deficiency induced by topical medication with the preservative benzalkonium chloride

Investigative Ophthalmology and Visual Science

Volumn 54, Issue 9, 2013, Pages 6314-6325

  Lin, Zhirong ^a   He, Huan ^a,b   Zhou, Tong ^a,b   Liu, Xiaochen ^a,b   Wang, Yihui ^a,b   He, Hui ^a,b   Wu, Huping ^a   Liu, Zuguo ^a,b  

^a XIAMEN UNIVERSITY   (China)

^b Fujian Provincial Key Laboratory of Ophthalmology and Visual Science   (China)

Author keywords

Benzalkonium chloride; Goblet cell; Inflammation; Limbal stem cell deficiency; Squamous metaplasia

Indexed keywords

BENZALKONIUM CHLORIDE; CELL MARKER; K 13; K 19; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORNEA DISEASE; CORNEA NEOVASCULARIZATION; DISEASE MODEL; GOBLET CELL; HISTOLOGY; IMMUNOHISTOCHEMISTRY; IMPRESSION CYTOLOGY; INFLAMMATION; LIMBAL STEM CELL DEFICIENCY; MALE; MOUSE; NONHUMAN; OCULAR SURFACE DISEASE; PERIODIC ACID SCHIFF STAIN; PRIORITY JOURNAL; SQUAMOUS CELL METAPLASIA; TRANSMISSION ELECTRON MICROSCOPY;

BENZALKONIUM CHLORIDE; GOBLET CELL; INFLAMMATION; LIMBAL STEM CELL DEFICIENCY; SQUAMOUS METAPLASIA;

ANIMALS; BENZALKONIUM COMPOUNDS; CELLS, CULTURED; CORNEAL DISEASES; DISEASE MODELS, ANIMAL; LIMBUS CORNEAE; MALE; MICE; MICE, INBRED BALB C; MICROSCOPY, ELECTRON, TRANSMISSION; OPHTHALMIC SOLUTIONS; PRESERVATIVES, PHARMACEUTICAL; STEM CELLS;

EID: 84884585120     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.12-10725     Document Type: Article

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