Oligopotent stem cells are distributed throughout the mammalian ocular surface

Nature

Volumn 456, Issue 7219, 2008, Pages 250-254

  Majo, François ^a,b,c   Rochat, Ariane ^a,b   Nicolas, Michael ^a,b   Jaoudé, Georges Abou ^a   Barrandon, Yann ^a,b  

^a EPFL   (Switzerland)

^b LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

^c HÔPITAL OPHTALMIQUE JULES GONIN   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

EYE; IDENTIFICATION METHOD; MEDICINE; MODEL; PIG; RODENT; VISION;

ARTICLE; CELL RENEWAL; CELLULAR DISTRIBUTION; CORNEA EPITHELIUM; CORNEA LIMBUS; GOBLET CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; STEM CELL;

ADULT STEM CELLS; ANIMALS; CATTLE; CELLS, CULTURED; CHILD, PRESCHOOL; CLONE CELLS; CORNEAL TRANSPLANTATION; EPITHELIUM, CORNEAL; FEMALE; GENE EXPRESSION REGULATION; HUMANS; INFANT; KERATINOCYTES; MALE; MICE; MICE, SCID; MODELS, BIOLOGICAL; MULTIPOTENT STEM CELLS; PROTEINS; RATS; SWINE;

MAMMALIA; SUIDAE;

EID: 56249122234     PISSN: 00280836     EISSN: 14764679     Source Type: Journal    
DOI: 10.1038/nature07406     Document Type: Article

References (35)

1. Whitcher, J. P., Srinivasan, M. & Upadhyay, M. P. Corneal blindness: a global perspective. Bull. World Health Organ. 79, 214-221 (2001).
2. Pellegrini, G. et al. Long-term restoration of damaged corneal surfaces with autologous cultivated corneal epithelium. Lancet 349, 990-993 (1997).
3. Haddad, A. Renewal of the rabbit corneal epithelium as investigated by autoradiography after intravitreal injection of 3H-thymidine. Cornea 19, 378-383 (2000).
4. Cotsarelis, G., Cheng, S. Z., Dong, G., Sun, T. T. & Lavker, R. M. Existence of slow-cycling limbal epithelial basal cells that can be preferentially stimulated to proliferate: implications on epithelial stem cells. Cell 57, 201-209 (1989).
5. Jones, P. H., Simons, B. D. & Watt, F. M. Sic transit gloria: farewell to the epidermal transit amplifying cell? Cell Stem Cell 1, 371-381 (2007).
6. Clayton, E. et al. A single type of progenitor cell maintains normal epidermis. Nature 446, 185-189 (2007).
7. Barrandon, Y. & Green, H. Three clonal types of keratinocyte with different capacities for multiplication. Proc. Natl Acad. Sci. USA 84, 2302-2306 (1987).
8. Pellegrini, G. et al. Location and clonal analysis of stem cells and their differentiated progeny in the human ocular surface. J. Cell Biol. 145, 769-782 (1999).
9. Puangsricharern, V. & Tseng, S. C. Cytologic evidence of corneal diseases with limbal stem cell deficiency. Ophthalmology 102, 1476-1485 (1995).
10. Buck, R. C. Cell migration in repair of mouse corneal epithelium. Invest. Ophthalmol. Vis. Sci. 18, 767-784 (1979).
11. Potten, C. S., Schofield, R. & Lajtha, L. G. A comparison of cell replacement in bone marrow, testis and three regions of surface epithelium. Biochim. Biophys. Acta 560, 281-299 (1979).
12. Claudinot, S., Nicolas, M., Oshima, H., Rochat, A. & Barrandon, Y. Long-term renewal of hair follicles from clonogenic multipotent stem cells. Proc. Natl Acad. Sci. USA 102, 14677-14682 (2005).
13. Kiel, M. J. et al. Haematopoietic stem cells do not asymmetrically segregate chromosomes or retain BrdU. Nature 449, 238-242 (2007).
14. Barker, N. et al. Identification of stem cells in small intestine and colon by marker gene Lgr5. Nature 449, 1003-1007 (2007).
15. Rama, P. et al. Autologous fibrin-cultured limbal stem cells permanently restore the corneal surface of patients with total limbal stem cell deficiency. Transplantation 72, 1478-1485 (2001).
16. Ronfard, V., Rives, J. M., Neveux, Y., Carsin, H. & Barrandon, Y. Long-term regeneration of human epidermis on third degree burns transplanted with autologous cultured epithelium grown on a fibrin matrix. Transplantation 70, 1588-1598 (2000).
17. Rochat, A., Kobayashi, K. & Barrandon, Y. Location of stem cells of human hair follicles by clonal analysis. Cell 76, 1063-1073 (1994).
18. Merkle, F. T., Tramontin, A. D., Garcia-Verdugo, J. M. & Alvarez-Buylla, A. Radial glia give rise to adult neural stem cells in the subventricular zone. Proc. Natl Acad. Sci. USA 101, 17528-17532 (2004).
19. Shapiro, M. S., Friend, J. & Thoft, R. A. Corneal re-epithelialization from the conjunctiva. Invest. Ophthalmol. Vis. Sci. 21, 135-142 (1981).
20. Thoft, R. A. Keratoepithelioplasty. Am. J. Ophthalmol. 97, 1-6 (1984).
21. Tanioka, H. et al. Establishment of a cultivated human conjunctival epithelium as an alternative tissue source for autologous corneal epithelial transplantation. Invest. Ophthalmol. Vis. Sci. 47, 3820-3827 (2006).
22. Ferraris, C., Chevalier, G., Favier, B., Jahoda, C. A. & Dhouailly, D. Adult corneal epithelium basal cells possess the capacity to activate epidermal, pilosebaceous and sweat gland genetic programs in response to embryonic dermal stimuli. Development 127, 5487-5495 (2000).
23. Vauclair, S. et al. Corneal epithelial cell fate is maintained during repair by Notch1 signaling via the regulation of vitamin A metabolism. Dev. Cell 13, 242-253 (2007).
24. Kawasaki, S. et al. Clusters of corneal epithelial cells reside ectopically in human conjunctival epithelium. Invest. Ophthalmol. Vis. Sci. 47, 1359-1367 (2006).
25. Di Iorio, E. et al. Isoforms of ΔNp63 and the migration of ocular limbal cells in human corneal regeneration. Proc. Natl Acad. Sci. USA 102, 9523-9528 (2005).
26. Barbaro, V. et al. C/EBPΔ regulates cell cycle and self-renewal of human limbal stem cells. J. Cell Biol. 177, 1037-1049 (2007).
27. Nakamura, T., Inatomi, T., Sotozono, C., Koizumi, N. & Kinoshita, S. Successful primary culture and autologous transplantation of corneal limbal epithelial cells from minimal biopsy for unilateral severe ocular surface disease. Acta Ophthalmol. Scand. 82, 468-471 (2004).
28. Oshima, H., Rochat, A., Kedzia, C., Kobayashi, K. & Barrandon, Y. Morphogenesis and renewal of hair follicles from adult multipotent stem cells. Cell 104, 233-245 (2001).
29. Pellegrini, G. et al. p63 identifies keratinocyte stem cells. Proc. Natl Acad. Sci. USA 98, 3156-3161 (2001).
30. Schermer, A., Galvin, S. & Sun, T. T. Differentiation-related expression of a major 64K corneal keratin in vivo and in culture suggests limbal location of corneal epithelial stem cells. J. Cell Biol. 103, 49-62 (1986).
31. Friedrich, G. & Soriano, P. Promoter traps in embryonic stem cells: a genetic screen to identify and mutate developmental genes in mice. Genes Dev. 5, 1513-1523 (1991).
32. Hadjantonakis, A. K., Gertsenstein, M., Ikawa, M., Okabe, M. & Nagy, A. Generating green fluorescent mice by germline transmission of green fluorescent ES cells. Mech. Dev. 76, 79-90 (1998).
33. Barrandon, Y. & Green, H. Cell size as a determinant of the clone-forming ability of human keratinocytes. Proc. Natl Acad. Sci. USA 82, 5390-5394 (1985).
34. Smyth, G. K. Linear models and empirical bayes methods for assessing differential expression in microarray experiments. Stat. Appl. Genet. Mol. Biol. 3, article-3 (2004).
35. Hochberg, Y. & Benjamini, Y. More powerful procedures for multiple significance testing. Stat. Med. 9, 811-818 (1990).