Clinical and cytological findings in limbal stem cell deficiency

Graefe's Archive for Clinical and Experimental Ophthalmology

Volumn 243, Issue 9, 2005, Pages 870-876

  Sacchetti, Marta ^a   Lambiase, Alessandro ^a   Cortes, Magdalena ^a   Sgrulletta, Roberto ^a   Bonini, Sergio ^b   Merlo, Daniela ^c   Bonini, Stefano ^a,b,d,e  

^a UNIVERSITY CAMPUS BIO MEDICO   (Italy)

^b IRCCS SAN RAFFAELE PISANA   (Italy)

^c UNIVERSITY OF ROME TOR VERGATA   (Italy)

^d IRCCS FONDAZIONE BIETTI   (Italy)

^e NONE   (Italy)

Author keywords

Corneal sensitivity; Cytokeratin 19; Cytokeratin 3; Impression cytology; Limbal stem cell deficiency

Indexed keywords

CYTOKERATIN;

ADOLESCENT; ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CLINICAL FEATURE; CONTROLLED STUDY; CORNEA EPITHELIUM; CORNEA SENSIBILITY; CORRELATION FUNCTION; CYTOLOGY; DIAGNOSTIC VALUE; EYE DISEASE; FEMALE; GOBLET CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; LIMBAL STEM CELL DEFICIENCY; MALE; NEOVASCULARIZATION (PATHOLOGY); PRIORITY JOURNAL; SCORING SYSTEM; STROMA;

ADOLESCENT; ADULT; AGED; BIOLOGICAL MARKERS; CORNEAL DISEASES; EPITHELIUM, CORNEAL; FEMALE; GOBLET CELLS; HUMANS; KERATIN-3; KERATINS; LIMBUS CORNEAE; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; SENSATION; STEM CELLS; TEARS;

EID: 25844474072     PISSN: 0721832X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00417-005-1159-0     Document Type: Article

References (25)

1. Anderson DF, Ellies P, Pires RT, Tseng SC (2001) Amniotic membrane transplantation for partial limbal stem cell deficiency. Br J Ophthalmol 85:567-575
2. Chen JJ, Tseng SC (1990) Corneal epithelial wound healing in partial limbal deficiency. Invest Ophthalmol Vis Sci 31:1301-1314
3. Cho P, Yap M (1993) Schirmer test. I. A review. Opt Vis Sci 70:152-156
4. Donisi PM, Rama P, Fasolo A, Ponzin D (2003) Analysis of limbal stem cell deficiency by corneal impression cytology. Cornea 22:533-538
5. Dua HS (1998) The conjunctiva in corneal epithelial wound healing. Br J Ophthalmol 82:1407-1411
6. Dua HS, Saini JS, Azuara-Blanco A, Gupta P (2000) Limbal stem cell deficiency: Concept, aetiology, clinical presentation, diagnosis and management. Indian J Ophthalmol 48:83-92
7. Elder MJ, Hiscott P, Dart JK (1997) Intermediate filament expression by normal and diseased human corneal epithelium. Hum Pathol 28:1348-1354
8. Espana EM, Di Pascuale MA, He H, Kawakita T, Raju VK, Liu CY, Tseng SC (2004) Characterisation of corneal pannus removed from patients with total limbal stem cell deficiency. Invest Ophthalmol Vis Sci 45:2961-2966
9. Espana EM, Grueterich M, Romano AC, Touhami A, Tseng SC (2002) Idiopathic limbal stem cell deficiency. Ophthalmology 109:2004-2010
10. Gown AM, Vogel AM (1984) Monoclonal antibodies to intermediate filament proteins of human cells. II. Distribution of filament proteins in normal human tissue. Am J Pathol 114:309-321
11. Gruterich M, Tseng SC (2002) Surgical approaches for limbal stem cell deficiency. Klin Monatsbl Augenheilkd 219:333-339
12. Huang AJW, Tseng SCG (1991) Corneal epithelial wound healing in the absence of limbal epithelium. Invest Ophthalmol Vis Sci 32:96-105
13. Jones LT (1966) The lacrimal secretory system and its treatment. Am J Ophthalmol 62:47-60
14. Kenyon KR, Tseng SC (1989) Limbal autograft transplantation for ocular surface disorders. Ophthalmology 96:709-722
15. Klaassen-Broekema N, Mackor AJ, van Bijsterveld OP (1992) The diagnostic power of the tests for tear gland related keratoconjunctivitis sicca. Neth J Med 40:113-116
16. Lambiase A, Manni L, Bonini S, Rama P, Micera A, Aloe L (2000) Nerve growth factor promotes corneal healing: Structural, biochemical, and molecular analyses of rat and human corneas. Invest Ophthalmol Vis Sci 41:1063-1069
17. Marinho D, Hofling-Lima AL, Kwitko S, Tseng SCG (2003) Does amniotic membrane transplantation improve the outcome of autologous limbal transplantation? Cornea 22:338-342
18. Martin XY, Safran AB (1988) Corneal hypoesthesia. Surv Ophthalmol 33:28-40
19. Nelson JD, Wright JC (1984) Conjunctival goblet cells densities in ocular surface disease. Arch Ophthalmol 102:1049-1051
20. Puangsricharern V, Tseng SC (1995) Cytologic evidence of corneal diseases with limbal stem cell deficiency. Ophthalmology 102:1476-1485
21. Rama P, Bonini S, Lambiase A, Golisano O, Paterna P, De Luca M, Pellegrini G (2001) Autologous fibrin-cultured limbal stem cells permanently restore the corneal surface of patients with total limbal stem cell deficiency. Transplantation 72:1478-1485
22. Sangwan VS (2001) Limbal stem cells in health and disease. Biosci Rep 21:385-405
23. Touhami A, Grueterich M, Tseng SCG (2002) The role of NGF signalling in human limbal epithelium expanded by amniotic membrane culture. Invest Ophthalmol Vis Sci 43:987-994
24. Tsai RJ, Li LM, Chen JK (2000) Reconstruction of damaged corneas by transplantation of autologous limbal epithelial cells. N Engl J Med 343:86-93
25. Tsai RJF, Sun TT, Tseng SCG (1990) Comparison of limbal and conjunctival autograft transplantation in corneal surface reconstruction in rabbits. Ophthalmology 97:446-455