Role of Per1 and the mineralocorticoid receptor in the coordinate regulation of αENaC in renal cortical collecting duct cells

Frontiers in Physiology

Volumn 4 SEP, Issue , 2013, Pages

  Richards, Jacob ^a,b   Jeffers, Lauren A ^b,c   All, Sean C ^a   Cheng, Kit Yan ^a   Gumz, Michelle L ^a,b  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF FLORIDA   (United States)

^c EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Circadian clock; E box; ENaC; Kidney; MR

Indexed keywords

ALDOSTERONE; ALPHA SUBUNIT OF THE RENAL EPITHELIAL SODIUM CHANNEL; DNA; MINERALOCORTICOID RECEPTOR; PER1 PROTEIN; UNCLASSIFIED DRUG;

ALDOSTERONE BLOOD LEVEL; ALDOSTERONE RELEASE; ALPHA ENAC GENE; ARTICLE; CHROMATIN IMMUNOPRECIPITATION; CIRCADIAN RHYTHM; CONTROLLED STUDY; DNA BINDING; E BOX ELEMENT; GENE; GENE MUTATION; GENE TARGETING; HUMAN; HUMAN CELL; KIDNEY COLLECTING TUBULE; PROMOTER REGION; PROTEIN DNA INTERACTION; PROTEIN EXPRESSION; REGULATORY MECHANISM; RENAL CORTICAL COLLECTING DUCT CELL; SITE DIRECTED MUTAGENESIS;

EID: 84884572842     PISSN: None     EISSN: 1664042X     Source Type: Journal    
DOI: 10.3389/fphys.2013.00253     Document Type: Article

References (32)

1. Agarwal, R. (2010). Regulation of circadian blood pressure: from mice to astronauts. Curr. Opin. Nephrol. Hypertens. 19, 51-58. doi: 10.1097/MNH.0b013e3283336ddb
2. Albrecht, U., and Eichele, G. (2003). The mammalian circadian clock. Curr. Opin. Genet. Dev. 13, 271-277. doi: 10.1016/S0959-437X(03)00055-8
3. Albrecht, U., Zheng, B., Larkin, D., Sun, Z. S., and Lee, C. C. (2001). MPer1 and mper2 are essential for normal resetting of the circadian clock. J. Biol. Rhythms 16, 100-104. doi: 10.1177/074873001129001791
4. Arriza, J. L., Weinberger, C., Cerelli, G., Glaser, T. M., Handelin, B. L., Housman, D. E., et al. (1987). Cloning of human mineralocorticoid receptor complementary DNA: structural and functional kinship with the glucocorticoid receptor. Science 237, 268-275. doi: 10.1126/science.3037703
5. Bens, M., Vallet, V., Cluzeaud, F., Pascual-Letallec, L., Kahn, A., Rafestin-Oblin, M. E., et al. (1999). Corticosteroid-dependent sodium transport in a novel immortalized mouse collecting duct principal cell line. J. Am. Soc. Nephrol. 10, 923-934.
6. Bugaj, V., Pochynyuk, O., Mironova, E., Vandewalle, A., Medina, J. L., and Stockand, J. D. (2008). Regulation of the epithelial Na+ channel by endothelin-1 in rat collecting duct. Am. J. Physiol. Renal Physiol. 295, F1063-F1070. doi: 10.1152/ajprenal.90321.2008
7. Chen, S. Y. E. A. (1999). Epithelial sodium channel regulated by aldosterone-induced protein sgk. Proc. Natl. Acad. Sci. U.S.A. 96, 2514-2519. doi: 10.1073/pnas.96.5.2514
8. Curtis, A. M., Cheng, Y., Kapoor, S., Reilly, D., Price, T. S., and Fitzgerald, G. A. (2007). Circadian variation of blood pressure and the vascular response to asynchronous stress. Proc. Natl. Acad. Sci. U.S.A. 104, 3450-3455. doi: 10.1073/pnas.0611680104
9. Dibner, C., Schibler, U., and Albrecht, U. (2010). The mammalian circadian timing system: organization and coordination of central and peripheral clocks. Annu. Rev. Physiol. 72, 517-549. doi: 10.1146/annurev-physiol-021909-135821
10. Doi, M., Takahashi, Y., Komatsu, R., Yamazaki, F., Yamada, H., Haraguchi, S., et al. (2010). Salt-sensitive hypertension in circadian clock-deficient Cry-null mice involves dysregulated adrenal Hsd3b6. Nat. Med. 16, 67-74. doi: 10.1038/nm.2061
11. Gumz, M. L., Cheng, K. Y., Lynch, I. J., Stow, L. R., Greenlee, M. M., Cain, B. D., et al. (2010). Regulation of alphaENaC expression by the circadian clock protein Period 1 in mpkCCD(c14) cells. Biochim. Biophys. Acta 1799, 622-629. doi: 10.1016/j.bbagrm.2010.09.003
12. Gumz, M. L., Popp, M. P., Wingo, C. S., and Cain, B. D. (2003). Early transcriptional effects of aldosterone in a mouse inner medullary collecting duct cell line. Am. J. Physiol. Renal Physiol. 285, F664-F673.
13. Gumz, M. L., Stow, L. R., Lynch, I. J., Greenlee, M. M., Rudin, A., Cain, B. D., et al. (2009). The circadian clock protein Period 1 regulates expression of the renal epithelial sodium channel in mice. J. Clin. Invest. 119, 2423-2434. doi: 10.1172/JCI36908
14. Kohn, J. A., Deshpande, K., and Ortlund, E. A. (2012). Deciphering modern glucocorticoid cross-pharmacology using ancestral corticosteroid receptors. J. Biol. Chem. 287, 16267-16275. doi: 10.1074/jbc. M112.346411
15. Kucera, N., Schmalen, I., Hennig, S., Ollinger, R., Strauss, H. M., Grudziecki, A., et al. (2012). Unwinding the differences of the mammalian PERIOD clock proteins from crystal structure to cellular function. Proc. Natl. Acad. Sci. U.S.A. 109, 3311-3316. doi: 10.1073/pnas.1113280109
16. Lamia, K. A., Papp, S. J., Yu, R. T., Barish, G. D., Uhlenhaut, N. H., Jonker, J. W., et al. (2011). Cryptochromes mediate rhythmic repression of the glucocorticoid receptor. Nature 480, 552-556. doi: 10.1038/nature10700
17. Lee, I. H., Campbell, C. R., Song, S. H., Day, M. L., Kumar, S., Cook, D. I., et al. (2009). The activity of the epithelial sodium channels is regulated by caveolin-1 via a Nedd4-2-dependent mechanism. J. Biol. Chem. 284, 12663-12669. doi: 10.1074/jbc. M809737200
18. Lowrey, P. L., and Takahashi, J. S. (2004). Mammalian circadian biology: elucidating genome-wide levels of temporal organization. Annu. Rev. Genomics Hum. Genet. 5, 407-441. doi: 10.1146/annurev.genom.5.061903.175925
19. Lubarski, I., Pihakaski-Maunsbach, K., Karlish, S. J., Maunsbach, A. B., and Garty, H. (2005). Interaction with the Na, K-ATPase and tissue distribution of FXYD5 (related to ion channel). J. Biol. Chem. 280, 37717-37724. doi: 10.1074/jbc. M506397200
20. Lynch, I. J., Welch, A. K., Kohan, D. E., Cain, B. D., and Wingo, C. S. (2013). Endothelin-1 inhibits sodium reabsorption by ETA and ETB receptors in the mouse cortical collecting duct. Am. J. Physiol. Renal Physiol. 305, F568-F573. doi: 10.1152/ajprenal.00613.2012
21. Mick, V. E., Itani, O. A., Loftus, R. W., Husted, R. F., Schmidt, T. J., and Thomas, C. P. (2001). The alpha-subunit of the epithelial sodium channel is an aldosteroneinduced transcript in mammalian collecting ducts, and this transcriptional response is mediated via distinct cis-elements in the 5'-flanking region of the gene. Mol. Endocrinol. 15, 575-588. doi: 10.1210/me.15.4.575
22. Nikolaeva, S., Pradervand, S., Centeno, G., Zavadova, V., Tokonami, N., Maillard, M., et al. (2012). The circadian clock modulates renal sodium handling. J. Am. Soc. Nephrol. 23, 1019-1026. doi: 10.1681/ASN.2011080842
23. Palmer, L. G., Patel, A., and Frindt, G. (2012). Regulation and dysregulation of epithelial Na+ channels. Clin. Exp. Nephrol. 16, 35-43. doi: 10.1007/s10157-011-0496-z
24. Richards, J., Greenlee, M. M., Jeffers, L. A., Cheng, K. Y., Guo, L., Eaton, D. C., et al. (2012). Inhibition of alphaENaC expression and ENaC activity following blockade of the circadian clock-regulatory kinases CKIdelta/epsilon. Am. J. Physiol. Renal Physiol. 303, F918-F927. doi: 10.1152/ajprenal.00678.2011
25. Richards, J., and Gumz, M. L. (2012). Advances in understanding the peripheral circadian clocks. FASEB J. 26, 3602-3613. doi: 10.1096/fj.12-203554
26. Richards, J., and Gumz, M. L. (2013). Mechanism of the circadian clock in physiology. Am. J. Physiol. Regul. Integr. Comp. Physiol. 304, R1053-R1064. doi: 10.1152/ajpregu.00066.2013
27. Schmutz, I., Ripperger, J. A., Baeriswyl-Aebischer, S., and Albrecht, U. (2010). The mammalian clock component PERIOD2 coordinates circadian output by interaction with nuclear receptors. Genes Dev. 24, 345-357. doi: 10.1101/gad.564110
28. Singletary, J. H., Chan, D., Samani, N. J., and Chong, N. W. (2008). The canonical E-box motif: a target for glucocorticoid action that drives rhythmic mouse Pai-1 transcription in vitro. Gene 420, 42-47. doi: 10.1016/j.gene.2008.05.004
29. Stow, L. R., and Gumz, M. L. (2011). The circadian clock in the kidney. J. Am. Soc. Nephrol. 22, 598-604. doi: 10.1681/ASN.2010080803
30. Stow, L. R., Richards, J., Cheng, K. Y., Lynch, I. J., Jeffers, L. A., Greenlee, M. M., et al. (2012). The circadian protein period 1 contributes to blood pressure control and coordinately regulates renal sodium transport genes. Hypertension 59, 1151-1156. doi: 10.1161/HYPERTENSIONAHA.112.190892
31. Yang, X., Downes, M., Yu, R. T., Bookout, A. L., He, W., Straume, M., et al. (2006). Nuclear receptor expression links the circadian clock to metabolism. Cell 126, 801-810. doi: 10.1016/j.cell.2006.06.050
32. Zuber, A. M., Centeno, G., Pradervand, S., Nikolaeva, S., Maquelin, L., Cardinaux, L., et al. (2009). Molecular clock is involved in predictive circadian adjustment of renal function. Proc. Natl. Acad. Sci. U.S.A. 106, 16523-16528. doi: 10.1073/pnas.0904890106