Type I interferon limits influenza virus-induced acute lung injury by regulation of excessive inflammation in mice

Antiviral Research

Volumn 99, Issue 3, 2013, Pages 230-237

  Arimori, Yojiro ^a   Nakamura, Risa ^a,d   Yamada, Hisakata ^a   Shibata, Kensuke ^a   Maeda, Naoyoshi ^b   Kase, Tetsuo ^c   Yoshikai, Yasunobu ^a  

^a KYUSHU UNIVERSITY   (Japan)

^b HOKKAIDO UNIVERSITY   (Japan)

^c OSAKA PREFECTURAL INSTITUTE OF PUBLIC HEALTH   (Japan)

^d NAGASAKI UNIVERSITY   (Japan)

Author keywords

Acute lung injury; Influenza; Interleukin 10; Type I interferon

Indexed keywords

ALPHA INTERFERON RECEPTOR; INTERFERON; INTERLEUKIN 10; ALPHA BETA INTERFERON RECEPTOR; ANTIVIRUS AGENT; GAMMA INTERFERON; INTERLEUKIN 12P70; INTERLEUKIN 1BETA; INTERLEUKIN 6; TUMOR NECROSIS FACTOR ALPHA;

ACUTE LUNG INJURY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; GENE INACTIVATION; IMMUNE RESPONSE; INFECTION PREVENTION; INFECTION RESISTANCE; INFLUENZA A (H1N1); INFLUENZA VIRUS A H1N1; LUNG INFECTION; MORBIDITY; MORTALITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; VIRUS LOAD; ANIMAL; C57BL MOUSE; DEFICIENCY; DOWN REGULATION; DRUG EFFECTS; FEMALE; GENETICS; HUMAN; IMMUNOLOGY; INFLUENZA, HUMAN; KNOCKOUT MOUSE; LUNG; MALE; PHYSIOLOGY; VIROLOGY; ANTIINFLAMMATORY ACTIVITY; ANTIVIRAL ACTIVITY; BONE MARROW; CYTOKINE PRODUCTION; ENZYME LINKED IMMUNOSORBENT ASSAY; IMMUNOPATHOLOGY; INFLUENZA; INFLUENZA VIRUS A H1N2; VIRAL CLEARANCE; WILD TYPE; DRUG EFFECT; TYPE I INTERFERON;

ACUTE LUNG INJURY; ANIMALS; ANTIVIRAL AGENTS; DOWN-REGULATION; FEMALE; HUMANS; INFLUENZA A VIRUS, H1N1 SUBTYPE; INFLUENZA, HUMAN; INTERFERON TYPE I; INTERLEUKIN-10; LUNG; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; RECEPTOR, INTERFERON ALPHA-BETA;

ACUTE LUNG INJURY; INFLUENZA; INTERLEUKIN-10; TYPE I INTERFERON;

EID: 84884564752     PISSN: 01663542     EISSN: 18729096     Source Type: Journal    
DOI: 10.1016/j.antiviral.2013.05.007     Document Type: Article

References (39)

1. Akbari O., DeKruyff R.H., Umetsu D.T. Pulmonary dendritic cells producing IL-10 mediate tolerance induced by respiratory exposure to antigen. Nature Immunology 2001, 2:725-731.
2. Billiau A. Anti-inflammatory properties of Type I interferons. Antiviral Research 2006, 71:108-116.
3. Bowie A.G., Unterholzner L. Viral evasion and subversion of pattern-recognition receptor signalling. Nature Reviews. Immunology 2008, 8:911-922.
4. Brown E.G. Increased virulence of a mouse-adapted variant of influenza A/FM/1/47 virus is controlled by mutations in genome segments 4, 5, 7, and 8. Journal of Virology 1990, 64:4523-4533.
5. Cuenca A.G., Delano M.J., Kelly-Scumpia K.M., Moreno C., Scumpia P.O., Laface D.M., Heyworth P.G., Efron P.A., Moldawer L.L. A paradoxical role for myeloid-derived suppressor cells in sepsis and trauma. Molecular Medicine 2011, 17:281-292.
6. Doherty P.C., Turner S.J., Webby R.G., Thomas P.G. Influenza and the challenge for immunology. Nature Immunology 2006, 7:449-455.
7. Gambotto A., Barratt-Boyes S.M., de Jong M.D., Neumann G., Kawaoka Y. Human infection with highly pathogenic H5N1 influenza virus. Lancet 2008, 371:1464-1475.
8. Gillim-Ross L., Subbarao K. Emerging respiratory viruses: challenges and vaccine strategies. Clinical Microbiology Reviews 2006, 19:614-636.
9. Gonzalez-Juarrero M., Shim T.S., Kipnis A., Junqueira-Kipnis A.P., Orme I.M. Dynamics of macrophage cell populations during murine pulmonary tuberculosis. Journal of Immunology 2003, 171:3128-3135.
10. Gonzalez-Navajas J.M., Lee J., David M., Raz E. Immunomodulatory functions of type I interferons. Nature Reviews. Immunology 2012, 12:125-135.
11. Guarda G., Braun M., Staehli F., Tardivel A., Mattmann C., Forster I., Farlik M., Decker T., Du Pasquier R.A., Romero P., Tschopp J. Type I interferon inhibits interleukin-1 production and inflammasome activation. Immunity 2011, 34:213-223.
12. Hale B.G., Randall R.E., Ortin J., Jackson D. The multifunctional NS1 protein of influenza A viruses. The Journal of General Virology 2008, 89:2359-2376.
13. Honda K., Yanai H., Negishi H., Asagiri M., Sato M., Mizutani T., Shimada N., Ohba Y., Takaoka A., Yoshida N., Taniguchi T. IRF-7 is the master regulator of type-I interferon-dependent immune responses. Nature 2005, 434:772-777.
14. Imai Y., Kuba K., Neely G.G., Yaghubian-Malhami R., Perkmann T., van Loo G., Ermolaeva M., Veldhuizen R., Leung Y.H., Wang H., Liu H., Sun Y., Pasparakis M., Kopf M., Mech C., Bavari S., Peiris J.S., Slutsky A.S., Akira S., Hultqvist M., Holmdahl R., Nicholls J., Jiang C., Binder C.J., Penninger J.M. Identification of oxidative stress and Toll-like receptor 4 signaling as a key pathway of acute lung injury. Cell 2008, 133:235-249.
15. Janssen W.J., Barthel L., Muldrow A., Oberley-Deegan R.E., Kearns M.T., Jakubzick C., Henson P.M. Fas determines differential fates of resident and recruited macrophages during resolution of acute lung injury. American Journal of Respiratory and Critical Care Medicine 2011, 184:547-560.
16. Koerner I., Kochs G., Kalinke U., Weiss S., Staeheli P. Protective role of beta interferon in host defense against influenza A virus. Journal of Virology 2007, 81:2025-2030.
17. Kolumam G.A., Thomas S., Thompson L.J., Sprent J., Murali-Krishna K. Type I interferons act directly on CD8 T cells to allow clonal expansion and memory formation in response to viral infection. The Journal of Experimental Medicine 2005, 202:637-650.
18. Lloyd C.M., Hawrylowicz C.M. Regulatory T cells in asthma. Immunity 2009, 31:438-449.
19. Maines T.R., Szretter K.J., Perrone L., Belser J.A., Bright R.A., Zeng H., Tumpey T.M., Katz J.M. Pathogenesis of emerging avian influenza viruses in mammals and the host innate immune response. Immunological Reviews 2008, 225:68-84.
20. Manca C., Tsenova L., Freeman S., Barczak A.K., Tovey M., Murray P.J., Barry C., Kaplan G. Hypervirulent M. tuberculosis W/Beijing strains upregulate type I IFNs and increase expression of negative regulators of the Jak-Stat pathway. Journal of Interferon & Cytokine Research: the Official Journal of the International Society for Interferon and Cytokine Research 2005, 25:694-701.
21. McKinstry K.K., Strutt T.M., Buck A., Curtis J.D., Dibble J.P., Huston G., Tighe M., Hamada H., Sell S., Dutton R.W., Swain S.L. IL-10 deficiency unleashes an influenza-specific Th17 response and enhances survival against high-dose challenge. Journal of Immunology 2009, 182:7353-7363.
22. Ng W.F., To K.F., Lam W.W., Ng T.K., Lee K.C. The comparative pathology of severe acute respiratory syndrome and avian influenza A subtype H5N1-a review. Human Pathology 2006, 37:381-390.
23. Nguyen K.B., Salazar-Mather T.P., Dalod M.Y., Van Deusen J.B., Wei X.Q., Liew F.Y., Caligiuri M.A., Durbin J.E., Biron C.A. Coordinated and distinct roles for IFN-alpha beta, IL-12, and IL-15 regulation of NK cell responses to viral infection. Journal of Immunology 2002, 169:4279-4287.
24. Okuno Y., Matsumoto K., Isegawa Y., Ueda S. Protection against the mouse-adapted A/FM/1/47 strain of influenza A virus in mice by a monoclonal antibody with cross-neutralizing activity among H1 and H2 strains. Journal of virology 1994, 68:517-520.
25. Peiris J.S., de Jong M.D., Guan Y. Avian influenza virus (H5N1): a threat to human health. Clinical Microbiology Reviews 2007, 20:243-267.
26. Platanias L.C. Mechanisms of type-I- and type-II-interferon-mediated signalling. Nature Reviews. Immunology 2005, 5:375-386.
27. Randall R.E., Goodbourn S. Interferons and viruses: an interplay between induction, signalling, antiviral responses and virus countermeasures. The Journal of General Virology 2008, 89:1-47.
28. Sadler A.J., Williams B.R. Interferon-inducible antiviral effectors. Nature Reviews. Immunology 2008, 8:559-568.
29. Saraiva M., O'Garra A. The regulation of IL-10 production by immune cells. Nature Reviews. Immunology 2010, 10:170-181.
30. Schmitz N., Kurrer M., Bachmann M.F., Kopf M. Interleukin-1 is responsible for acute lung immunopathology but increases survival of respiratory influenza virus infection. Journal of Virology 2005, 79:6441-6448.
31. Seo S.U., Kwon H.J., Ko H.J., Byun Y.H., Seong B.L., Uematsu S., Akira S., Kweon M.N. Type I interferon signaling regulates Ly6C(hi) monocytes and neutrophils during acute viral pneumonia in mice. PLoS Pathogens 2011, 7:e1001304.
32. Smith A.G., Sheridan P.A., Tseng R.J., Sheridan J.F., Beck M.A. Selective impairment in dendritic cell function and altered antigen-specific CD8+ T-cell responses in diet-induced obese mice infected with influenza virus. Immunology 2009, 126:268-279.
33. Stockinger S., Decker T. Novel functions of type I interferons revealed by infection studies with Listeria monocytogenes. Immunobiology 2008, 213:889-897.
34. Sun J., Madan R., Karp C.L., Braciale T.J. Effector T cells control lung inflammation during acute influenza virus infection by producing IL-10. Nature Medicine 2009, 15:277-284.
35. Sun K., Torres L., Metzger D.W. A detrimental effect of interleukin-10 on protective pulmonary humoral immunity during primary influenza A virus infection. Journal of Virology 2010, 84:5007-5014.
36. Szretter K.J., Gangappa S., Belser J.A., Zeng H., Chen H., Matsuoka Y., Sambhara S., Swayne D.E., Tumpey T.M., Katz J.M. Early control of H5N1 influenza virus replication by the type I interferon response in mice. Journal of Virology 2009, 83:5825-5834.
37. Takeuchi O., Akira S. Innate immunity to virus infection. Immunological Reviews 2009, 227:75-86.
38. Taubenberger J.K., Morens D.M. The pathology of influenza virus infections. Annual Review of Pathology 2008, 3:499-522.
39. Wissinger E., Goulding J., Hussell T. Immune homeostasis in the respiratory tract and its impact on heterologous infection. Seminars in Immunology 2009, 21:147-155.