메뉴 건너뛰기




Volumn 14, Issue 9, 2013, Pages 19294-19308

Oxidative stress in the pathogenesis of keratoconus and Fuchs endothelial corneal dystrophy

Author keywords

Antioxidants; Free radicals; Fuchs endothelial corneal dystrophy; Keratoconus; Oxidative stress

Indexed keywords

ALDEHYDE DEHYDROGENASE; COLLAGEN TYPE 4; COLLAGEN TYPE 8; GLUTATHIONE TRANSFERASE; METALLOTHIONEIN III; MITOCHONDRIAL DNA; PEROXIREDOXIN; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE; THIOREDOXIN REDUCTASE;

EID: 84884564440     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms140919294     Document Type: Review
Times cited : (126)

References (78)
  • 1
    • 79960383133 scopus 로고    scopus 로고
    • Melatonin protects against oxidative stress in granular corneal dystrophy type 2 corneal fibroblasts by mechanisms that involve membrane melatonin receptors
    • Choi, S.I.; Dadakhujaev, S.; Ryu, H.; Im Kim, T.; Kim, E.K. Melatonin protects against oxidative stress in granular corneal dystrophy type 2 corneal fibroblasts by mechanisms that involve membrane melatonin receptors. J. Pineal Res. 2011, 51, 94-103.
    • (2011) J. Pineal Res , vol.51 , pp. 94-103
    • Choi, S.I.1    Dadakhujaev, S.2    Ryu, H.3    Im Kim, T.4    Kim, E.K.5
  • 3
    • 0031670727 scopus 로고    scopus 로고
    • Nuclear ferritin protects DNA from UV damage in corneal epithelial cells
    • Cai, C.X.; Birk, D.E.; Linsenmayer, T.F. Nuclear ferritin protects DNA from UV damage in corneal epithelial cells. Mol. Biol. Cell. 1998, 9, 1037-1051.
    • (1998) Mol. Biol. Cell , vol.9 , pp. 1037-1051
    • Cai, C.X.1    Birk, D.E.2    Linsenmayer, T.F.3
  • 4
    • 77049120544 scopus 로고    scopus 로고
    • Antioxidant defenses in the ocular surface
    • Chen, Y.; Mehta, G.; Vasiliou, V. Antioxidant defenses in the ocular surface. Ocul. Surf. 2009, 7, 176-185.
    • (2009) Ocul. Surf , vol.7 , pp. 176-185
    • Chen, Y.1    Mehta, G.2    Vasiliou, V.3
  • 6
    • 0036086130 scopus 로고    scopus 로고
    • Free radicals in the physiological control of cell function
    • Dröge, W. Free radicals in the physiological control of cell function. Physiol. Rev. 2002, 82, 47-95.
    • (2002) Physiol. Rev , vol.82 , pp. 47-95
    • Dröge, W.1
  • 7
    • 0034626735 scopus 로고    scopus 로고
    • Oxidants, oxidative stress and the biology of ageing
    • Finkel, T.; Holbrook, N.J. Oxidants, oxidative stress and the biology of ageing. Nature 2000, 408, 239-247.
    • (2000) Nature , vol.408 , pp. 239-247
    • Finkel, T.1    Holbrook, N.J.2
  • 9
    • 79956191022 scopus 로고    scopus 로고
    • Role of oxidative stress and DNA damage in human carcinogenesis
    • Kryston, T.B.; Georgiev, A.B.; Pissis, P.; Georgakilas, A.G. Role of oxidative stress and DNA damage in human carcinogenesis. Mutat. Res. 2011, 711, 193-201.
    • (2011) Mutat. Res , vol.711 , pp. 193-201
    • Kryston, T.B.1    Georgiev, A.B.2    Pissis, P.3    Georgakilas, A.G.4
  • 10
    • 32444433202 scopus 로고    scopus 로고
    • Free radicals, metals and antioxidants in oxidative stress-induced cancer
    • Valko, M.; Rhodes, C.J.; Moncol, J.; Izakovic, M.; Mazur, M. Free radicals, metals and antioxidants in oxidative stress-induced cancer. Chem. Biol. Interact. 2006, 160, 1-40.
    • (2006) Chem. Biol. Interact , vol.160 , pp. 1-40
    • Valko, M.1    Rhodes, C.J.2    Moncol, J.3    Izakovic, M.4    Mazur, M.5
  • 11
    • 16244366485 scopus 로고    scopus 로고
    • Increased levels of catalase and cathepsin V/L2 but decreased TIMP-1 in keratoconus corneas: Evidence that oxidative stress plays a role in this disorder
    • Kenney, M.C.; Chwa, M.; Atilano, S.R.; Tran, A.; Carballo, M.; Saghizadeh, M.; Vasiliou, V.; Adachi, W.; Brown, D.J. Increased levels of catalase and cathepsin V/L2 but decreased TIMP-1 in keratoconus corneas: Evidence that oxidative stress plays a role in this disorder. Invest. Ophthalmol. Vis. Sci. 2005, 46, 823-832.
    • (2005) Invest. Ophthalmol. Vis. Sci , vol.46 , pp. 823-832
    • Kenney, M.C.1    Chwa, M.2    Atilano, S.R.3    Tran, A.4    Carballo, M.5    Saghizadeh, M.6    Vasiliou, V.7    Adachi, W.8    Brown, D.J.9
  • 13
    • 78149321314 scopus 로고    scopus 로고
    • Evidence of oxidative stress in the pathogenesis of fuchs endothelial corneal dystrophy
    • Jurkunas, U.V.; Bitar, M.S.; Funaki, T.; Azizi, B. Evidence of oxidative stress in the pathogenesis of fuchs endothelial corneal dystrophy. Am. J. Pathol. 2010, 177, 2278-2289.
    • (2010) Am. J. Pathol , vol.177 , pp. 2278-2289
    • Jurkunas, U.V.1    Bitar, M.S.2    Funaki, T.3    Azizi, B.4
  • 15
    • 0025071241 scopus 로고
    • Free radicals and antioxidants in the pathogenesis of eye diseases
    • Marak, G.E.; de Kozak, Y.; Faure, J.P. Free radicals and antioxidants in the pathogenesis of eye diseases. Adv. Exp. Med. Biol. 1990, 264, 513-527.
    • (1990) Adv. Exp. Med. Biol , vol.264 , pp. 513-527
    • Marak, G.E.1    de Kozak, Y.2    Faure, J.P.3
  • 16
    • 0036804710 scopus 로고    scopus 로고
    • Free radicals, antioxidants, and nutrition
    • Fang, Y.Z.; Yang, S.; Wu, G. Free radicals, antioxidants, and nutrition. Nutrition 2002, 18, 872-879.
    • (2002) Nutrition , vol.18 , pp. 872-879
    • Fang, Y.Z.1    Yang, S.2    Wu, G.3
  • 19
    • 0036867895 scopus 로고    scopus 로고
    • Oxidation of biological systems: Oxidative stress phenomena, antioxidants, redox reactions, and methods for their quantification
    • Kohen, R.; Nyska, A. Oxidation of biological systems: Oxidative stress phenomena, antioxidants, redox reactions, and methods for their quantification. Toxicol. Pathol. 2002, 30, 620-650.
    • (2002) Toxicol. Pathol , vol.30 , pp. 620-650
    • Kohen, R.1    Nyska, A.2
  • 20
    • 29344446328 scopus 로고    scopus 로고
    • Targeting antioxidants to mitochondria: A new therapeutic direction
    • Sheu, S.S.; Nauduri, D.; Anders, M.W. Targeting antioxidants to mitochondria: A new therapeutic direction. Biochim. Biophys. Acta 2006, 1762, 256-265.
    • (2006) Biochim. Biophys. Acta , vol.1762 , pp. 256-265
    • Sheu, S.S.1    Nauduri, D.2    Anders, M.W.3
  • 21
    • 0030894162 scopus 로고    scopus 로고
    • Oxidative stress: Oxidants and antioxidants
    • Sies, H. Oxidative stress: Oxidants and antioxidants. Exp. Physiol. 1997, 82, 291-295.
    • (1997) Exp. Physiol , vol.82 , pp. 291-295
    • Sies, H.1
  • 27
    • 2442424281 scopus 로고    scopus 로고
    • Morphological changes in keratoconus: Pathology or pathogenesis
    • Sherwin, T.; Brookes, N.H. Morphological changes in keratoconus: Pathology or pathogenesis. Clin. Exp. Ophthalmol. 2004, 32, 211-217.
    • (2004) Clin. Exp. Ophthalmol , vol.32 , pp. 211-217
    • Sherwin, T.1    Brookes, N.H.2
  • 28
    • 84877921331 scopus 로고    scopus 로고
    • Insights into keratoconus from a genetic perspective
    • Burdon, K.P.; Vincent, A.L. Insights into keratoconus from a genetic perspective. Clin. Exp. Optom. 2013, 96, 146-154.
    • (2013) Clin. Exp. Optom , vol.96 , pp. 146-154
    • Burdon, K.P.1    Vincent, A.L.2
  • 30
    • 0042381808 scopus 로고    scopus 로고
    • The cascade hypothesis of keratoconus
    • Kenney, M.C.; Brown, D.J. The cascade hypothesis of keratoconus. Cont. Lens Anterior Eye 2003, 26, 139-146.
    • (2003) Cont. Lens Anterior Eye , vol.26 , pp. 139-146
    • Kenney, M.C.1    Brown, D.J.2
  • 36
    • 33744748888 scopus 로고    scopus 로고
    • Increased stress-induced generation of reactive oxygen species and apoptosis in human keratoconus fibroblasts
    • Chwa, M.; Atilano, S.R.; Reddy, V.; Jordan, N.; Kim, D.W.; Kenney, M.C. Increased stress-induced generation of reactive oxygen species and apoptosis in human keratoconus fibroblasts. Invest. Ophthalmol. Vis. Sci. 2006, 47, 1902-1910.
    • (2006) Invest. Ophthalmol. Vis. Sci , vol.47 , pp. 1902-1910
    • Chwa, M.1    Atilano, S.R.2    Reddy, V.3    Jordan, N.4    Kim, D.W.5    Kenney, M.C.6
  • 38
    • 0032171410 scopus 로고    scopus 로고
    • Oxidative chemistry of nitric oxide: The roles of superoxide, peroxynitrite, and carbon dioxide
    • Squadrito, G.L.; Pryor, W.A. Oxidative chemistry of nitric oxide: the roles of superoxide, peroxynitrite, and carbon dioxide. Free Radic. Biol. Med. 1998, 25, 392-403.
    • (1998) Free Radic. Biol. Med , vol.25 , pp. 392-403
    • Squadrito, G.L.1    Pryor, W.A.2
  • 40
    • 0034659147 scopus 로고    scopus 로고
    • Role of reactive aldehyde in cardiovascular diseases
    • Uchida, K. Role of reactive aldehyde in cardiovascular diseases. Free Radic. Biol. Med. 2000, 28, 1685-1696.
    • (2000) Free Radic. Biol. Med , vol.28 , pp. 1685-1696
    • Uchida, K.1
  • 41
    • 0027959916 scopus 로고
    • Protective effects of lazaroids against oxygen-free radicals induced lysosomal damage
    • Kalra, J.; Mantha, S.V.; Kumar, P.; Prasad, K. Protective effects of lazaroids against oxygen-free radicals induced lysosomal damage. Mol. Cell. Biochem. 1994,136, 125-129.
    • (1994) Mol. Cell. Biochem , vol.136 , pp. 125-129
    • Kalra, J.1    Mantha, S.V.2    Kumar, P.3    Prasad, K.4
  • 43
    • 2342593995 scopus 로고    scopus 로고
    • Elements of the nitric oxide pathway can degrade TIMP-1 and increase gelatinase activity
    • Brown, D.J.; Lin, B.; Chwa, M.; Atilano, S.R.; Kim, D.W.; Kenney, M.C. Elements of the nitric oxide pathway can degrade TIMP-1 and increase gelatinase activity. Mol. Vis. 2004, 10, 281-288.
    • (2004) Mol. Vis , vol.10 , pp. 281-288
    • Brown, D.J.1    Lin, B.2    Chwa, M.3    Atilano, S.R.4    Kim, D.W.5    Kenney, M.C.6
  • 44
    • 34547216853 scopus 로고    scopus 로고
    • Interleukin-1alpha downregulates extracellular-superoxide dismutase in human corneal keratoconus stromal cells
    • Olofsson, E.M.; Marklund, S.L.; Pedrosa-Domellöf, F.; Behndig, A. Interleukin-1alpha downregulates extracellular-superoxide dismutase in human corneal keratoconus stromal cells. Mol. Vis. 2007, 13, 1285-1290.
    • (2007) Mol. Vis , vol.13 , pp. 1285-1290
    • Olofsson, E.M.1    Marklund, S.L.2    Pedrosa-Domellöf, F.3    Behndig, A.4
  • 45
    • 0036667555 scopus 로고    scopus 로고
    • Superoxide dismutase multigene family: A comparison of the CuZn-SOD (SOD1), Mn-SOD (SOD2), and EC-SOD (SOD3) gene structures, evolution, and expression
    • Zelko, I.N.; Mariani, T.J.; Folz, R.J. Superoxide dismutase multigene family: A comparison of the CuZn-SOD (SOD1), Mn-SOD (SOD2), and EC-SOD (SOD3) gene structures, evolution, and expression. Free Radic. Biol. Med. 2002, 33, 337-349.
    • (2002) Free Radic. Biol. Med , vol.33 , pp. 337-349
    • Zelko, I.N.1    Mariani, T.J.2    Folz, R.J.3
  • 46
    • 0346724680 scopus 로고    scopus 로고
    • Human aldehyde dehydrogenase 3A1 (ALDH3A1): Biochemical characterization and immunohistochemical localization in the cornea
    • Pappa, A.; Estey, T.; Manzer, R.; Brown, D.; Vasiliou, V. Human aldehyde dehydrogenase 3A1 (ALDH3A1): Biochemical characterization and immunohistochemical localization in the cornea. Biochem. J. 2003, 376, 615-23.
    • (2003) Biochem. J , vol.376 , pp. 615-623
    • Pappa, A.1    Estey, T.2    Manzer, R.3    Brown, D.4    Vasiliou, V.5
  • 47
    • 79851516092 scopus 로고    scopus 로고
    • Measurement of oxidized/reduced glutathione ratio
    • Owen, J.B.; Butterfield, D.A. Measurement of oxidized/reduced glutathione ratio. Methods Mol. Biol. 2010, 648, 269-277.
    • (2010) Methods Mol. Biol , vol.648 , pp. 269-277
    • Owen, J.B.1    Butterfield, D.A.2
  • 48
    • 0035670014 scopus 로고    scopus 로고
    • Is the corneal degradation in keratoconus caused by matrix-metalloproteinases?
    • Collier, S.A. Is the corneal degradation in keratoconus caused by matrix-metalloproteinases? Clin. Exp. Ophthalmol. 2001, 29, 340-344.
    • (2001) Clin. Exp. Ophthalmol , vol.29 , pp. 340-344
    • Collier, S.A.1
  • 50
    • 0035033889 scopus 로고    scopus 로고
    • Tissue inhibitor of metalloproteinase-1 prevents cytokine-mediated dysfunction and cytotoxicity in pancreatic islets and beta-cells
    • Han, X.; Sun, Y.; Scott, S.; Bleich, D. Tissue inhibitor of metalloproteinase-1 prevents cytokine-mediated dysfunction and cytotoxicity in pancreatic islets and beta-cells. Diabetes 2001, 50, 1047-1055.
    • (2001) Diabetes , vol.50 , pp. 1047-1055
    • Han, X.1    Sun, Y.2    Scott, S.3    Bleich, D.4
  • 51
    • 0029130713 scopus 로고
    • Over-expression of a gelatinase A activity in keratoconus
    • Smith, V.A.; Hoh, H.B.; Littleton, M.; Easty, D.L. Over-expression of a gelatinase A activity in keratoconus. Eye 1995, 9, 429-433.
    • (1995) Eye , vol.9 , pp. 429-433
    • Smith, V.A.1    Hoh, H.B.2    Littleton, M.3    Easty, D.L.4
  • 54
    • 0004118364 scopus 로고    scopus 로고
    • An Introduction to Mitochondria. History of the Mitochondrial Free Radical Theory of Aging
    • In, R.G. Landes Company: Austin, TX, USA 1954-1995
    • De Grey, A.D.N.J. An Introduction to Mitochondria. History of the Mitochondrial Free Radical Theory of Aging, 1954-1995; In The Mitochondrial Free Radical Theory of Aging; R.G. Landes Company: Austin, TX, USA, 1999; pp. 20-30, 66-69.
    • (1999) The Mitochondrial Free Radical Theory of Aging
    • de Grey, A.D.N.J.1
  • 55
    • 84855394783 scopus 로고    scopus 로고
    • Oxidative stress, mitochondrial dysfunction, and aging
    • 2012
    • Cui, H.; Kong, Y.; Zhang, H. Oxidative stress, mitochondrial dysfunction, and aging. J. Signal. Transduct. 2012, 2012, 646354.
    • (2012) J. Signal. Transduct , pp. 646354
    • Cui, H.1    Kong, Y.2    Zhang, H.3
  • 56
    • 17744393686 scopus 로고    scopus 로고
    • Mitochondrial DNA mutations in human disease
    • Taylor, R.W.; Turnbull, D.M. Mitochondrial DNA mutations in human disease. Nat. Rev. Genet. 2005, 6, 389-402.
    • (2005) Nat. Rev. Genet , vol.6 , pp. 389-402
    • Taylor, R.W.1    Turnbull, D.M.2
  • 60
    • 84872239595 scopus 로고    scopus 로고
    • Cellular and subbasal nerve alterations in early stage Fuchs' endothelial corneal dystrophy: An in vivo confocal microscopy study
    • Schrems-Hoesl, L.M.; Schrems, W.A.; Cruzat, A.; Shahatit, B.M.; Bayhan, H.A.; Jurkunas, U.V.; Hamrah P. Cellular and subbasal nerve alterations in early stage Fuchs' endothelial corneal dystrophy: An in vivo confocal microscopy study. Eye 2013, 27, 42-49.
    • (2013) Eye , vol.27 , pp. 42-49
    • Schrems-Hoesl, L.M.1    Schrems, W.A.2    Cruzat, A.3    Shahatit, B.M.4    Bayhan, H.A.5    Jurkunas, U.V.6    Hamrah, P.7
  • 61
    • 79951864480 scopus 로고    scopus 로고
    • Fuchs endothelial corneal dystrophy
    • Elhalis, H.; Azizi, B.; Jurkunas, U.V. Fuchs endothelial corneal dystrophy. Ocul. Surf. 2010, 8. 173-184.
    • (2010) Ocul. Surf , vol.8 , pp. 173-184
    • Elhalis, H.1    Azizi, B.2    Jurkunas, U.V.3
  • 62
    • 84856542436 scopus 로고    scopus 로고
    • Molecular bases of corneal endothelial dystrophies
    • Schmedt, T.; Silva, M.M.; Ziaei, A.; Jurkunas, U. Molecular bases of corneal endothelial dystrophies. Exp. Eye Res. 2012, 95, 24-34.
    • (2012) Exp. Eye Res , vol.95 , pp. 24-34
    • Schmedt, T.1    Silva, M.M.2    Ziaei, A.3    Jurkunas, U.4
  • 63
    • 79954956679 scopus 로고    scopus 로고
    • Human corneal endothelial cell expansion for corneal endothelium transplantation: An overview
    • Peh, G.S.; Beuerman, R.W.; Colman, A.; Tan, D.T.; Mehta, J.S. Human corneal endothelial cell expansion for corneal endothelium transplantation: An overview. Transplantation 2011, 91, 811-819.
    • (2011) Transplantation , vol.91 , pp. 811-819
    • Peh, G.S.1    Beuerman, R.W.2    Colman, A.3    Tan, D.T.4    Mehta, J.S.5
  • 64
    • 0037279996 scopus 로고    scopus 로고
    • Identity and regulation of ion transport mechanisms in the corneal endothelium
    • Bonanno, J.A. Identity and regulation of ion transport mechanisms in the corneal endothelium. Prog. Retin. Eye Res. 2003, 22, 69-94.
    • (2003) Prog. Retin. Eye Res , vol.22 , pp. 69-94
    • Bonanno, J.A.1
  • 70
    • 0034605446 scopus 로고    scopus 로고
    • Role of the heat shock response and molecular chaperones in oncogenesis and cell death
    • Jolly, C.; Morimoto, R.I. Role of the heat shock response and molecular chaperones in oncogenesis and cell death. J. Natl. Cancer Inst. 2000, 92, 1564-1572.
    • (2000) J. Natl. Cancer Inst , vol.92 , pp. 1564-1572
    • Jolly, C.1    Morimoto, R.I.2
  • 72
    • 0035584857 scopus 로고    scopus 로고
    • Reactive oxygen species, antioxidants, and the mammalian thioredoxin system
    • Nordberg, J.; Arnér, E.S. Reactive oxygen species, antioxidants, and the mammalian thioredoxin system. Free Radic. Biol. Med. 2001, 31, 1287-1312.
    • (2001) Free Radic. Biol. Med , vol.31 , pp. 1287-1312
    • Nordberg, J.1    Arnér, E.S.2
  • 74
    • 0038146898 scopus 로고    scopus 로고
    • Identification of the NF-E2-related factor-2-dependent genes conferring protection against oxidative stress in primary cortical astrocytes using oligonucleotide microarray analysis
    • Lee, J.M.; Calkins, M.J.; Chan, K.; Kan, Y.W.; Johnson, J.A. Identification of the NF-E2-related factor-2-dependent genes conferring protection against oxidative stress in primary cortical astrocytes using oligonucleotide microarray analysis. J. Biol. Chem. 2003, 278, 12029-12038.
    • (2003) J. Biol. Chem , vol.278 , pp. 12029-12038
    • Lee, J.M.1    Calkins, M.J.2    Chan, K.3    Kan, Y.W.4    Johnson, J.A.5
  • 75
    • 0034717329 scopus 로고    scopus 로고
    • Transcription factor Nrf2 coordinately regulates a group of oxidative stress-inducible genes in macrophages
    • Ishii, T.; Itoh, K.; Takahashi, S.; Sato, H.; Yanagawa, T.; Katoh, Y.; Bannai, S.; Yamamoto, M. Transcription factor Nrf2 coordinately regulates a group of oxidative stress-inducible genes in macrophages. J. Biol. Chem. 2000, 275, 16023-16029.
    • (2000) J. Biol. Chem , vol.275 , pp. 16023-16029
    • Ishii, T.1    Itoh, K.2    Takahashi, S.3    Sato, H.4    Yanagawa, T.5    Katoh, Y.6    Bannai, S.7    Yamamoto, M.8
  • 77
    • 84866247628 scopus 로고    scopus 로고
    • DNA damage and base excision repair in mitochondria and their role in aging
    • 2011
    • Gredilla, R. DNA damage and base excision repair in mitochondria and their role in aging. J. Aging Res. 2010, 2011, 257093.
    • (2010) J. Aging Res , pp. 257093
    • Gredilla, R.1
  • 78
    • 0035782650 scopus 로고    scopus 로고
    • Reactive oxygen species and mitochondrial diseases
    • Kirkinezos, I.G.; Moraes, C.T. Reactive oxygen species and mitochondrial diseases. Semin. Cell Dev. Biol. 2001, 12, 449-457.
    • (2001) Semin. Cell Dev. Biol , vol.12 , pp. 449-457
    • Kirkinezos, I.G.1    Moraes, C.T.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.