CXCL8-induced FAK phosphorylation via CXCR1 and CXCR2: Cytoskeleton- and integrin-related mechanisms converge with FAK regulatory pathways in a receptor-specific manner

Cytokine

Volumn 33, Issue 1, 2006, Pages 1-16

  Cohen Hillel, Efrat ^a   Yron, Ilana ^a   Meshel, Tsipi ^a   Soria, Gali ^a   Attal, Hila ^a   Ben Baruch, Adit ^a  

^a TEL AVIV UNIVERSITY   (Israel)

Author keywords

CXCL8; CXCR1; CXCR2; Focal adhesion kinase

Indexed keywords

ACTIN; BETA TUBULIN; CHEMOKINE; CHEMOKINE RECEPTOR CXCR1; CHEMOKINE RECEPTOR CXCR2; FIBRONECTIN; FOCAL ADHESION KINASE; GROWTH FACTOR; INTEGRIN; INTERLEUKIN 8; INTERLEUKIN 8 RECEPTOR;

ACTIN FILAMENT; ANIMAL CELL; ARTICLE; CELL ADHESION; CELL MIGRATION; CELL TYPE; CONTROLLED STUDY; CYTOSKELETON; DISSOCIATION; EMBRYO; ENDOTHELIUM CELL; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT; REGULATORY MECHANISM; TUMOR CELL;

CELL LINE; CELL MIGRATION INHIBITION; CELL MOVEMENT; CYTOSKELETON; FOCAL ADHESION KINASE 1; HUMANS; INTEGRINS; INTERLEUKIN-8; MICROSCOPY, CONFOCAL; MICROTUBULES; MODELS, BIOLOGICAL; PHOSPHORYLATION; RECEPTORS, INTERLEUKIN-8A; RECEPTORS, INTERLEUKIN-8B; SIGNAL TRANSDUCTION; TRANSFECTION;

ANIMALIA;

EID: 32344445820     PISSN: 10434666     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cyto.2005.11.006     Document Type: Article

References (62)

1. A. Rot, and U.H. von Andrian Chemokines in innate and adaptive host defense: basic chemokinese grammar for immune cells Annu Rev Immunol 22 2004 891 928
2. J. Middleton, A.M. Patterson, L. Gardner, C. Schmutz, and B.A. Ashton Leukocyte extravasation: chemokine transport and presentation by the endothelium Blood 100 2002 3853 3860
3. C. Weber Novel mechanistic concepts for the control of leukocyte transmigration: specialization of integrins, chemokines, and junctional molecules J Mol Med 81 2003 4 19
4. M.N. Devalaraja, and A. Richmond Multiple chemotactic factors: fine control or redundancy? Trends Pharmacol Sci 20 1999 151 156
5. A. Mantovani The chemokine system: redundancy for robust outputs Immunol Today 20 1999 254 257
6. D.D. Schlaepfer, C.R. Hauck, and D.J. Sieg Signaling through focal adhesion kinase Prog Biophys Mol Biol 71 1999 435 478
7. M.D. Schaller Biochemical signals and biological responses elicited by the focal adhesion kinase Biochim Biophys Acta 1540 2001 1 21
8. C.R. Hauck, D.A. Hsia, and D.D. Schlaepfer The focal adhesion kinase - a regulator of cell migration and invasion IUBMB Life 53 2002 115 119
9. J.T. Parsons Focal adhesion kinase: the first ten years J Cell Sci 116 2003 1409 1416
10. J.T. Parsons, K.H. Martin, J.K. Slack, J.M. Taylor, and S.A. Weed Focal adhesion kinase: a regulator of focal adhesion dynamics and cell movement Oncogene 19 2000 5606 5613
11. A.J. Ridley, M.A. Schwartz, K. Burridge, R.A. Firtel, M.H. Ginsberg, and G. Borisy Cell migration: integrating signals from front to back Science 302 2003 1704 1709
12. C.R. Hauck, C.K. Klingbeil, and D.D. Schlaepfer Focal adhesion kinase functions as a receptor-proximal signaling component required for directed cell migration Immunol Res 21 2000 293 303
13. D.D. Schlaepfer, and S.K. Mitra Multiple connections link FAK to cell motility and invasion Curr Opin Genet Dev 14 2004 92 101
14. D. Ilic, C.H. Damsky, and T. Yamamoto Focal adhesion kinase: at the crossroads of signal transduction J Cell Sci 110 Pt 4 1997 401 407
15. M.A. Williams, and J.S. Solomkin Integrin-mediated signaling in human neutrophil functioning J Leukoc Biol 65 1999 725 736
16. R.A. Worthylake, and K. Burridge Leukocyte transendothelial migration: orchestrating the underlying molecular machinery Curr Opin Cell Biol 13 2001 569 577
17. C. Laudanna, J.Y. Kim, G. Constantin, and E. Butcher Rapid leukocyte integrin activation by chemokines Immunol Rev 186 2002 37 46
18. P.M. Murphy, M. Baggiolini, I.F. Charo, C.A. Hebert, R. Horuk, and K. Matsushima International union of pharmacology. XXII. Nomenclature for chemokine receptors Pharmacol Rev 52 2000 145 176
19. A. Chuntharapai, and K.J. Kim Regulation of the expression of IL-8 receptor A/B by IL-8: possible functions of each receptor J Immunol 155 1995 2587 2594
20. N. Mukaida Interleukin-8: an expanding universe beyond neutrophil chemotaxis and activation Int J Hematol 72 2000 391 398
21. I.U. Schraufstatter, J. Chung, and M. Burger IL-8 activates endothelial cell CXCR1 and CXCR2 through Rho and Rac signaling pathways Am J Physiol Lung Cell Mol Physiol 280 2001 L1094 L1103
22. I.U. Schraufstatter, K. Trieu, M. Zhao, D.M. Rose, R.A. Terkeltaub, and M. Burger IL-8-mediated cell migration in endothelial cells depends on cathepsin B activity and transactivation of the epidermal growth factor receptor J Immunol 171 2003 6714 6722
23. R. Ramjeesingh, R. Leung, and C.H. Siu Interleukin-8 secreted by endothelial cells induces chemotaxis of melanoma cells through the chemokine receptor CXCR1 Faseb J 17 2003 1292 1294
24. A. Sturm, D.C. Baumgart, J.H. d'Heureuse, A. Hotz, B. Wiedenmann, and A.U. Dignass CXCL8 modulates human intestinal epithelial cells through a CXCR1 dependent pathway Cytokine 29 2005 42 48
25. P.M. Murphy, and H.L. Tiffany Cloning of complementary DNA encoding a functional human interleukin-8 receptor Science 253 1991 1280 1283
26. W.E. Holmes, J. Lee, W.J. Kuang, G.C. Rice, and W.I. Wood Structure and functional expression of a human interleukin-8 receptor Science 253 1991 1278 1280
27. T. Geiser, B. Dewald, M.U. Ehrengruber, I. Clark-Lewis, and M. Baggiolini The interleukin-8-related chemotactic cytokines GRO alpha, GRO beta, and GRO gamma activate human neutrophil and basophil leukocytes J Biol Chem 268 1993 15419 15424
28. A. Kurdowska, A.B. Cohen, F.K. Carr, M.D. Stevens, E.J. Miller, and G. Mullenbach Biological and kinetic characterization of recombinant human macrophage inflammatory peptides 2 alpha and beta and comparison with the neutrophil activating peptide 2 and interleukin 8 Cytokine 6 1994 124 134
29. I. Clark-Lewis, B. Dewald, T. Geiser, B. Moser, and M. Baggiolini Platelet factor 4 binds to interleukin 8 receptors and activates neutrophils when its N terminus is modified with Glu-Leu-Arg Proc Natl Acad Sci USA 90 1993 3574 3577
30. P.M. Grob, E. David, T.C. Warren, R.P. DeLeon, P.R. Farina, and C.A. Homon Characterization of a receptor for human monocyte-derived neutrophil chemotactic factor/interleukin-8 J Biol Chem 265 1990 8311 8316
31. P. Loetscher, M. Seitz, I. Clark-Lewis, M. Baggiolini, and B. Moser Both interleukin-8 receptors independently mediate chemotaxis. Jurkat cells transfected with IL-8R1 or IL-8R2 migrate in response to IL-8, GRO alpha and NAP-2 FEBS Lett 341 1994 187 192
32. A. Ben-Baruch, M. Grimm, K. Bengali, G.A. Evans, O. Chertov, and J.M. Wang The differential ability of IL-8 and neutrophil-activating peptide-2 to induce attenuation of chemotaxis is mediated by their divergent capabilities to phosphorylate CXCR2 (IL-8 receptor B) J Immunol 158 1997 5927 5933
33. R. Feniger-Barish, I. Yron, T. Meshel, E. Matityahu, and A. Ben-Baruch IL-8-induced migratory responses through CXCR1 and CXCR2: association with phosphorylation and cellular redistribution of focal adhesion kinase Biochemistry 42 2003 2874 2886
34. S.A. Jones, B. Moser, and M. Thelen A comparison of post-receptor signal transduction events in Jurkat cells transfected with either IL-8R1 or IL-8R2. Chemokine mediated activation of p42/p44 MAP-kinase (ERK-2) FEBS Lett 364 1995 211 214
35. S.G. Mueller, J.R. White, W.P. Schraw, V. Lam, and A. Richmond Ligand-induced desensitization of the human CXC chemokine receptor-2 is modulated by multiple serine residues in the carboxyl-terminal domain of the receptor J Biol Chem 272 1997 8207 8214
36. A.M. Lefer, G. Johnson 3rd, X.L. Ma, P.S. Tsao, and G.R. Thomas Cardioprotective and endothelial protective effects of[Ala-IL8]77 in a rabbit model of myocardial ischaemia and reperfusion Br J Pharmacol 103 1991 1153 1159
37. M.T. Wiekowski, S.C. Chen, P. Zalamea, B.P. Wilburn, D.J. Kinsley, and W.W. Sharif Disruption of neutrophil migration in a conditional transgenic model: evidence for CXCR2 desensitization in vivo J Immunol 167 2001 7102 7110
38. W.S. Simonet, T.M. Hughes, H.Q. Nguyen, L.D. Trebasky, D.M. Danilenko, and E.S. Medlock Long-term impaired neutrophil migration in mice over expressing human interleukin-8 J Clin Invest 94 1994 1310 1319
39. K. Ley, J.B. Baker, M.I. Cybulsky, M.A. Gimbrone Jr., and F.W. Luscinskas Intravenous interleukin-8 inhibits granulocyte emigration from rabbit mesenteric venules without altering L-selectin expression or leukocyte rolling J Immunol 151 1993 6347 6357
40. A. Ben-Baruch, K. Bengali, K. Tani, L. Xu, J.J. Oppenheim, and J.M. Wang IL-8 and NAP-2 differ in their capacities to bind and chemoattract 293 cells transfected with either IL-8 receptor type A or type B Cytokine 9 1997 37 45
41. R. Feniger-Barish, M. Ran, A. Zaslaver, and A. Ben-Baruch Differential modes of regulation of cxc chemokine-induced internalization and recycling of human CXCR1 and CXCR2 Cytokine 11 1999 996 1009
42. R.M. Richardson, R.A. DuBose, H. Ali, E.D. Tomhave, B. Haribabu, and R. Snyderman Regulation of human interleukin-8 receptor A: identification of a phosphorylation site involved in modulating receptor functions Biochemistry 34 1995 14193 14201
43. A. Wuyts, N. Van Osselaer, A. Haelens, I. Samson, P. Herdewijn, and A. Ben-Baruch Characterization of synthetic human granulocyte chemotactic protein 2: usage of chemokine receptors CXCR1 and CXCR2 and in vivo inflammatory properties Biochemistry 36 1997 2716 2723
44. A. Ben-Baruch, K.M. Bengali, A. Biragyn, J.J. Johnston, J.M. Wang, and J. Kim Interleukin-8 receptor beta. The role of the carboxyl terminus in signal transduction J Biol Chem 270 1995 9121 9128
45. K. Ley Integration of inflammatory signals by rolling neutrophils Immunol Rev 186 2002 8 18
46. K. Nakamura, H. Yano, E. Schaefer, and H. Sabe Different modes and qualities of tyrosine phosphorylation of Fak and Pyk2 during epithelial-mesenchymal transdifferentiation and cell migration: analysis of specific phosphorylation events using site-directed antibodies Oncogene 20 2001 2626 2635
47. A.F. Palazzo, and G.G. Gundersen Microtubule-actin cross-talk at focal adhesions Sci STKE PE31 2002 1 4
48. O. Krylyshkina, K.I. Anderson, I. Kaverina, I. Upmann, D.J. Manstein, and J.V. Small Nanometer targeting of microtubules to focal adhesions J Cell Biol 161 2003 853 859
49. A. Obergfell, K. Eto, A. Mocsai, C. Buensuceso, S.L. Moores, and J.S. Brugge Coordinate interactions of Csk, Src, and Syk kinases with[alpha]IIb[beta] 3 initiate integrin signaling to the cytoskeleton J Cell Biol 157 2002 265 275
50. D.D. Schlaepfer, K.C. Jones, and T. Hunter Multiple Grb2-mediated integrin-stimulated signaling pathways to ERK2/mitogen-activated protein kinase: summation of both c-Src- and focal adhesion kinase-initiated tyrosine phosphorylation events Mol Cell Biol 18 1998 2571 2585
51. L.K. Needham, and E. Rozengurt Galpha12 and Galpha13 stimulate Rho-dependent tyrosine phosphorylation of focal adhesion kinase, paxillin, and p130 Crk-associated substrate J Biol Chem 273 1998 14626 14632
52. L. Davidson, A.J. Pawson, R.P. Millar, and S. Maudsley Cytoskeletal reorganization dependence of signaling by the gonadotropin-releasing hormone receptor J Biol Chem 279 2004 1980 1993
53. J.L. Rodriguez-Fernandez, M. Gomez, A. Luque, N. Hogg, F. Sanchez-Madrid, and C. Cabanas The interaction of activated integrin lymphocyte function-associated antigen 1 with ligand intercellular adhesion molecule 1 induces activation and redistribution of focal adhesion kinase and proline-rich tyrosine kinase 2 in T lymphocytes Mol Biol Cell 10 1999 1891 1907
54. J. Kirchner, Z. Kam, G. Tzur, A.D. Bershadsky, and B. Geiger Live-cell monitoring of tyrosine phosphorylation in focal adhesions following microtubule disruption J Cell Sci 116 2003 975 986
55. S. Kook, S.R. Shim, J.I. Kim, J.H. Ahnn, Y.K. Jung, and S.G. Paik Degradation of focal adhesion proteins during nocodazole-induced apoptosis in rat-1 cells Cell Biochem Funct 18 2000 1 7
56. I. Kaverina, O. Krylyshkina, and J.V. Small Microtubule targeting of substrate contacts promotes their relaxation and dissociation J Cell Biol 146 1999 1033 1044
57. I. Kaverina, K. Rottner, and J.V. Small Targeting, capture, and stabilization of microtubules at early focal adhesions J Cell Biol 142 1998 181 190
58. A. Bhatt, I. Kaverina, C. Otey, and A. Huttenlocher Regulation of focal complex composition and disassembly by the calcium-dependent protease calpain J Cell Sci 115 2002 3415 3425
59. D.D. Schlaepfer, and T. Hunter Integrin signalling and tyrosine phosphorylation: just the FAKs? Trends Cell Biol 8 1998 151 157
60. R.M. Richardson, H. Ali, B.C. Pridgen, B. Haribabu, and R. Snyderman Multiple signaling pathways of human interleukin-8 receptor A. Independent regulation by phosphorylation J Biol Chem 273 1998 10690 10695
61. R.M. Richardson, B.C. Pridgen, B. Haribabu, H. Ali, and R. Snyderman Differential cross-regulation of the human chemokine receptors CXCR1 and CXCR2. Evidence for time-dependent signal generation J Biol Chem 273 1998 23830 23836
62. R.M. Richardson, R.J. Marjoram, L.S. Barak, and R. Snyderman Role of the cytoplasmic tails of CXCR1 and CXCR2 in mediating leukocyte migration, activation, and regulation J Immunol 170 2003 2904 2911