Soft sensor control of metabolic fluxes in a recombinant Escherichia coli fed-batch cultivation producing green fluorescence protein

Bioprocess and Biosystems Engineering

Volumn 36, Issue 10, 2013, Pages 1375-1384

  Gustavsson, Robert ^a   Mandenius, Carl Fredrik ^a  

^a LINKÖPING UNIVERSITY   (Sweden)

Author keywords

Bioprocess monitoring and control; Fed batch cultivation control; Mixed acid fermentation; Overflow metabolism; Soft sensors; Software sensors

Indexed keywords

BIOPROCESS MONITORING; FED-BATCH CULTIVATION; MIXED-ACID FERMENTATIONS; OVERFLOW METABOLISM; SOFT SENSORS; SOFTWARE SENSOR;

BIOMOLECULES; ESCHERICHIA COLI; FERMENTATION; INTEGRAL EQUATIONS; METABOLISM; METABOLITES; PHYSIOLOGY; RECOMBINANT PROTEINS;

SENSORS;

GREEN FLUORESCENT PROTEIN;

ARTICLE; BATCH PROCESS; BIOMASS; BIOPROCESS; BIOREACTOR; BIOSENSOR; CONTROLLED STUDY; ESCHERICHIA COLI; FED BATCH CULTURE; FEEDBACK SYSTEM; GLYCOLYSIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MATHEMATICAL COMPUTING; NEAR INFRARED SPECTROSCOPY; NONHUMAN; OPTICAL DENSITY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; SENSORY FEEDBACK; SIGNAL TRANSDUCTION; SPECIES CULTIVATION;

BIOMASS; BIOREACTORS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CULTURE MEDIA; ESCHERICHIA COLI; FERMENTATION; GREEN FLUORESCENT PROTEINS; KINETICS; RECOMBINATION, GENETIC; SPECTROSCOPY, NEAR-INFRARED;

EID: 84884559746     PISSN: 16157591     EISSN: 16157605     Source Type: Journal    
DOI: 10.1007/s00449-012-0840-z     Document Type: Article

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