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Volumn 31, Issue 2, 2008, Pages 145-152

Software sensors for fermentation processes

Author keywords

Biomass; Growth rate; Oxygen transfer; Process analytical technology (PAT); Software sensor; Stress

Indexed keywords

BIOMASS; BIOREACTORS; FERMENTATION; GROWTH RATE; MATHEMATICAL MODELS; SOFTWARE ARCHITECTURE;

EID: 38349147666     PISSN: 16157591     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00449-007-0157-5     Document Type: Article
Times cited : (33)

References (27)
  • 1
    • 33747175248 scopus 로고    scopus 로고
    • Process analytical technology in biopharmaceutical production: Past successes and future challenges
    • 1
    • Larsson TM, Lam H (2004) Process analytical technology in biopharmaceutical production: past successes and future challenges. J Process Anal Technol 1(1):20-22
    • (2004) J Process Anal Technol , vol.1 , pp. 20-22
    • Larsson, T.M.1    Lam, H.2
  • 2
    • 8444230152 scopus 로고    scopus 로고
    • Chemometrics in bioprocess engineering: Process analytical technology (PAT) applications
    • 2
    • Lopes JA, Costa PF, Alves TP, Menezes JC (2004) Chemometrics in bioprocess engineering: process analytical technology (PAT) applications. Chemom Intell Lab Syst 74(2):269-275
    • (2004) Chemom Intell Lab Syst , vol.74 , pp. 269-275
    • Lopes, J.A.1    Costa, P.F.2    Alves, T.P.3    Menezes, J.C.4
  • 3
    • 2542508565 scopus 로고    scopus 로고
    • Software sensors in bioprocess engineering
    • Chéruy A (1997) Software sensors in bioprocess engineering. J Biotechnol 52:193-199
    • (1997) J Biotechnol , vol.52 , pp. 193-199
    • Chéruy, A.1
  • 6
    • 33847165998 scopus 로고    scopus 로고
    • Utilizing PAT to monitor and control bulk biotech processes
    • Eli Lilly and Company University of Michigan:
    • Cooley RE, Eli Lilly and Company (2003) Utilizing PAT to monitor and control bulk biotech processes. Pharmaceutical Engineering Seminars, University of Michigan: http://www.fda.gov/cder/OPS/PAT.htm
    • (2003) Pharmaceutical Engineering Seminars
    • Cooley, R.E.1
  • 7
    • 1042273355 scopus 로고    scopus 로고
    • Process analytical chemistry-future trends in industry
    • Kueppers S, Haider M (2003) Process analytical chemistry-future trends in industry. Anal Bioanal Chem 376:313-315
    • (2003) Anal Bioanal Chem , vol.376 , pp. 313-315
    • Kueppers, S.1    Haider, M.2
  • 8
    • 33748938728 scopus 로고    scopus 로고
    • Bioprocess monitoring and computer control: Key roots of the current PAT initiative
    • 2
    • Junker BH, Wang HY (2006) Bioprocess monitoring and computer control: key roots of the current PAT initiative. Biotechnol Bioeng 95(2):226-261
    • (2006) Biotechnol Bioeng , vol.95 , pp. 226-261
    • Junker, B.H.1    Wang, H.Y.2
  • 9
    • 0000561546 scopus 로고
    • Fed-batch techniques in microbial processes
    • Yamane T, Shimizu S (1984) Fed-batch techniques in microbial processes. Adv Biochem Eng/Biotechnol 30:148-192
    • (1984) Adv Biochem Eng/Biotechnol , vol.30 , pp. 148-192
    • Yamane, T.1    Shimizu, S.2
  • 10
    • 0021507507 scopus 로고
    • Studies on on-line bioreactor identification. III. Sensitivity problems with respiratory and heat evolution measurements
    • Grosz R, Stephanopoulos G, San K-Y (1984) Studies on on-line bioreactor identification. III. Sensitivity problems with respiratory and heat evolution measurements. Biotechnol Bioeng 26:1198-1208
    • (1984) Biotechnol Bioeng , vol.26 , pp. 1198-1208
    • Grosz, R.1    Stephanopoulos, G.2    San, K.-Y.3
  • 11
    • 0037955821 scopus 로고    scopus 로고
    • Generally applicable fed-batch culture concept based on the detection of metabolic state by on-line balancing
    • 6
    • Jobé AM, Herwig C, Surzyn M, Walker B, Marison I, Stockar Uv (2003) Generally applicable fed-batch culture concept based on the detection of metabolic state by on-line balancing. Biotechnol Bioeng 82(6):627-639
    • (2003) Biotechnol Bioeng , vol.82 , pp. 627-639
    • Jobé, A.M.1    Herwig, C.2    Surzyn, M.3    Walker, B.4    Marison, I.5    Uv, S.6
  • 12
    • 0037009261 scopus 로고    scopus 로고
    • Growth and proton exchange in recombinant Escherichia coli BL21
    • Christensen Lykkegaard M, Eriksen NT (2002) Growth and proton exchange in recombinant Escherichia coli BL21. Enzyme Microb Technol 31:566-574
    • (2002) Enzyme Microb Technol , vol.31 , pp. 566-574
    • Christensen Lykkegaard, M.1    Eriksen, N.T.2
  • 13
    • 0035813451 scopus 로고    scopus 로고
    • Automatic inducer addition and harvesting of recombinant Escherichia coli cultures based on indirect on-line estimation of biomass concentration and specific growth rate
    • 3
    • Eriksen NT, Kratchmarova I, Neve S, Kristiansen K, Iversen Lønsmann JJ (2001) Automatic inducer addition and harvesting of recombinant Escherichia coli cultures based on indirect on-line estimation of biomass concentration and specific growth rate. Biotechnol Bioeng 75(3):355-361
    • (2001) Biotechnol Bioeng , vol.75 , pp. 355-361
    • Eriksen, N.T.1    Kratchmarova, I.2    Neve, S.3    Kristiansen, K.4    Iversen Lønsmann, J.J.5
  • 14
    • 0028027806 scopus 로고
    • On-line growth measurements in bioreactors by titrating metabolic proton exchange
    • Iversen JJL, Thomsen JK, Cox RP (1994) On-line growth measurements in bioreactors by titrating metabolic proton exchange. Appl Microbiol Biotechnol 42:256-262
    • (1994) Appl Microbiol Biotechnol , vol.42 , pp. 256-262
    • Iversen, J.J.L.1    Thomsen, J.K.2    Cox, R.P.3
  • 15
    • 84975842426 scopus 로고    scopus 로고
    • Simple technique for simultaneous on-line estimation of biomass and acetate from base consumption and conductivity measurements in high-cell density cultures of Escherichia coli
    • 3
    • Hoffmann F, Schmidt M, Rinas U (2000) Simple technique for simultaneous on-line estimation of biomass and acetate from base consumption and conductivity measurements in high-cell density cultures of Escherichia coli. Biotechnol Bioeng 70(3):358-361
    • (2000) Biotechnol Bioeng , vol.70 , pp. 358-361
    • Hoffmann, F.1    Schmidt, M.2    Rinas, U.3
  • 16
    • 0032550840 scopus 로고    scopus 로고
    • On-line estimation of biomass through pH control analysis in aerobic yeast fermentation systems
    • 4
    • Vicente A, Castrillo JI, Teixeira JA, Ugalde U (1998) On-line estimation of biomass through pH control analysis in aerobic yeast fermentation systems. Biotechnol Bioeng 58(4):445-450
    • (1998) Biotechnol Bioeng , vol.58 , pp. 445-450
    • Vicente, A.1    Castrillo, J.I.2    Teixeira, J.A.3    Ugalde, U.4
  • 17
    • 0021506692 scopus 로고
    • Studies on on-line bioreactor identification. IV. Utilization of pH measurements for product estimation
    • San K-Y, Stephanopoulos G (1984) Studies on on-line bioreactor identification. IV. Utilization of pH measurements for product estimation. Biotechnol Bioeng 26:1209-1218
    • (1984) Biotechnol Bioeng , vol.26 , pp. 1209-1218
    • San, K.-Y.1    Stephanopoulos, G.2
  • 18
    • 0028852142 scopus 로고
    • Proton production and consumption pathways in yeast metabolism. a chemostat culture analysis
    • Castrillo JI, Miguel Id, Ugalde UO (1995) Proton production and consumption pathways in yeast metabolism. A chemostat culture analysis. Yeast 11:1353-1365
    • (1995) Yeast , vol.11 , pp. 1353-1365
    • Castrillo, J.I.1    Id, M.2    Ugalde, U.O.3
  • 19
    • 0025059821 scopus 로고
    • The proton extrusion of growing yeast cultures as an on-line parameter in fermentation processes: Determination of biomass production and substrate consumption in batch experiments with Candida maltosa EH 15 D
    • 7
    • Huth J, Blasig R, Werner S, Müller H-G (1990) The proton extrusion of growing yeast cultures as an on-line parameter in fermentation processes: determination of biomass production and substrate consumption in batch experiments with Candida maltosa EH 15 D. J Basic Microbiol 30(7):481-488
    • (1990) J Basic Microbiol , vol.30 , pp. 481-488
    • Huth, J.1    Blasig, R.2    Werner, S.3    Müller, H.-G.4
  • 20
    • 0029361229 scopus 로고
    • On the use of the pH control reagent addition rate for fermentation monitoring
    • 6
    • Siano SA (1995) On the use of the pH control reagent addition rate for fermentation monitoring. Biotechnol Bioeng 47(6):651-665
    • (1995) Biotechnol Bioeng , vol.47 , pp. 651-665
    • Siano, S.A.1
  • 21
    • 0033944251 scopus 로고    scopus 로고
    • Characteristics of a DO-controlled fed-batch culture of Escherichia coli
    • Castan A, Enfors S-O (2000) Characteristics of a DO-controlled fed-batch culture of Escherichia coli. Bioprocess Eng 22:509-515
    • (2000) Bioprocess Eng , vol.22 , pp. 509-515
    • Castan, A.1    Enfors, S.-O.2
  • 22
    • 21644447627 scopus 로고    scopus 로고
    • Segregation to non-dividing cells in recombinant Escherichia coli fed-batch fermentation processes
    • Sundström H, Wållberg F, Ledung E, Norrman B, Hewitt CJ, Enfors S-O (2004) Segregation to non-dividing cells in recombinant Escherichia coli fed-batch fermentation processes. Biotechnol Lett 26:1533-1539
    • (2004) Biotechnol Lett , vol.26 , pp. 1533-1539
    • Sundström, H.1    Wållberg, F.2    Ledung, E.3    Norrman, B.4    Hewitt, C.J.5    Enfors, S.-O.6
  • 23
    • 0030595042 scopus 로고    scopus 로고
    • Rapid sampling, cell inactivation and evaluation of low extracellular glucose concentrations during fed-batch cultivation
    • Larsson G, Törnkvist M (1996) Rapid sampling, cell inactivation and evaluation of low extracellular glucose concentrations during fed-batch cultivation. J Biotechnol 49:69-82
    • (1996) J Biotechnol , vol.49 , pp. 69-82
    • Larsson, G.1    Törnkvist, M.2
  • 25
    • 0033047059 scopus 로고    scopus 로고
    • Modelling of overflow metabolism in batch and fed-batch cultures of Escherichia coli
    • Xu B, Jahic M, Enfors S-O (1999) Modelling of overflow metabolism in batch and fed-batch cultures of Escherichia coli. Biotechnol Prog 15:81-90
    • (1999) Biotechnol Prog , vol.15 , pp. 81-90
    • Xu, B.1    Jahic, M.2    Enfors, S.-O.3
  • 26
    • 0016787183 scopus 로고
    • Effects of varying the carbon source limiting growth on yield and maintenance characteristics of Escherichia coli in continuous culture
    • 3
    • Hempfling WP, Mainzer SE (1975) Effects of varying the carbon source limiting growth on yield and maintenance characteristics of Escherichia coli in continuous culture. J Bacteriol 123(3):1076-1087
    • (1975) J Bacteriol , vol.123 , pp. 1076-1087
    • Hempfling, W.P.1    Mainzer, S.E.2
  • 27
    • 0026608065 scopus 로고
    • Isopropyl-β-d-thiogalactopyranoside influences the metabolism of Escherichia coli
    • Kosinski MJ, Rinas U, Bailey JE (1992) Isopropyl-β-d- thiogalactopyranoside influences the metabolism of Escherichia coli. Appl Microbiol Biotechnol 36:782-784
    • (1992) Appl Microbiol Biotechnol , vol.36 , pp. 782-784
    • Kosinski, M.J.1    Rinas, U.2    Bailey, J.E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.