Lung fibrosis-associated surfactant protein A1 and C variants induce latent transforming growth factor β1 secretion in lung epithelial cells

Journal of Biological Chemistry

Volumn 288, Issue 38, 2013, Pages 27159-27171

  Maitra, Meenakshi ^a   Dey, Moushumi ^a   Yuan, Wen Cheng ^a   Nathanielsz, Peter W ^b   Garcia, Christine Kim ^a,c  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^c UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4-PHENYLBUTYRIC ACID; BINDING PROTEINS; LUNG EPITHELIAL CELLS; MOLECULAR CHAPERONES; PULMONARY FIBROSIS; SURFACTANT PROTEINS; TRANSFORMING GROWTH FACTORS; UNFOLDED PROTEIN RESPONSE;

BIOLOGICAL ORGANS; CELL CULTURE; CELL DEATH; SURFACE ACTIVE AGENTS;

PROTEINS;

4 PHENYLBUTYRIC ACID; ACTIVATING TRANSCRIPTION FACTOR 6; GENOMIC DNA; INOSITOL REQUIRING ENZYME 1ALPHA; MEMBRANE PROTEIN; MUTANT PROTEIN; SURFACTANT PROTEIN A1; SURFACTANT PROTEIN C; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; AUTOCRINE EFFECT; BABOON; CELL DEATH; CONTROLLED STUDY; CYTOKINE RELEASE; DRUG TARGETING; FETUS; GENE SILENCING; HUMAN; HUMAN CELL; LUNG ALVEOLUS EPITHELIUM; LUNG FIBROSIS; NONHUMAN; PARACRINE SIGNALING; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN INDUCTION; UNFOLDED PROTEIN RESPONSE;

GENETICS; PULMONARY FIBROSIS; PULMONARY SURFACTANT; TRANSFORMING GROWTH FACTOR BETA (TGFBETA); UNFOLDED PROTEIN RESPONSE;

AMINO ACID SUBSTITUTION; ANIMALS; ANTINEOPLASTIC AGENTS; AUTOCRINE COMMUNICATION; CELL DEATH; CELL LINE; EPITHELIAL CELLS; FEMALE; HUMANS; MALE; MOLECULAR CHAPERONES; MUTATION, MISSENSE; PAPIO; PARACRINE COMMUNICATION; PHENYLBUTYRATES; PULMONARY FIBROSIS; PULMONARY SURFACTANT-ASSOCIATED PROTEIN A; PULMONARY SURFACTANT-ASSOCIATED PROTEIN C; RESPIRATORY MUCOSA; SIGNAL TRANSDUCTION; TRANSFORMING GROWTH FACTOR BETA1; UNFOLDED PROTEIN RESPONSE;

EID: 84884553939     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.475335     Document Type: Article

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