-
1
-
-
0033623848
-
IKKepsilon is part of a novel PMA-inducible IkappaB kinase complex
-
Peters RT, Liao SM, Maniatis T. IKKepsilon is part of a novel PMA-inducible IkappaB kinase complex. Mol Cell 2000;5:513-22
-
(2000)
Mol Cell
, vol.5
, pp. 513-522
-
-
Peters, R.T.1
Liao, S.M.2
Maniatis, T.3
-
2
-
-
0034643170
-
NAK is an IkappaB kinase-activating kinase
-
Tojima Y, Fujimoto A, Delhase M, et al. NAK is an IkappaB kinase-activating kinase. Nature 2000;404:778-82
-
(2000)
Nature
, vol.404
, pp. 778-782
-
-
Tojima, Y.1
Fujimoto, A.2
Delhase, M.3
-
3
-
-
0038363463
-
Triggering the interferon antiviral response through an IKK-related pathway
-
Sharma S, tenOever BR, Grandvaux N, et al. Triggering the interferon antiviral response through an IKK-related pathway. Science 2003;300:1148-51
-
(2003)
Science
, vol.300
, pp. 1148-1151
-
-
Sharma, S.1
Tenoever, B.R.2
Grandvaux, N.3
-
4
-
-
79960042770
-
Targeted therapy in non-small-cell lung cancer-is it becoming a reality
-
Janku F, Stewart DJ, Kurzrock R. Targeted therapy in non-small-cell lung cancer-is it becoming a reality? Nat Rev Clin Oncol 2010;7:401-14
-
(2010)
Nat Rev Clin Oncol
, vol.7
, pp. 401-414
-
-
Janku, F.1
Stewart, D.J.2
Kurzrock, R.3
-
5
-
-
34249993765
-
Integrative genomic approaches identify IKBKE as a breast cancer oncogene
-
Boehm JS, Zhao JJ, Yao J, et al. Integrative genomic approaches identify IKBKE as a breast cancer oncogene. Cell 2007;129:1065-79
-
(2007)
Cell
, vol.129
, pp. 1065-1079
-
-
Boehm, J.S.1
Zhao, J.J.2
Yao, J.3
-
6
-
-
84872201790
-
IKBKE is induced by STAT3 and tobacco carcinogen and determines chemosensitivity in non-small cell lung cancer
-
Guo J, Kim D, Gao J, et al. IKBKE is induced by STAT3 and tobacco carcinogen and determines chemosensitivity in non-small cell lung cancer. Oncogene 2013;32:151-9
-
(2013)
Oncogene
, vol.32
, pp. 151-159
-
-
Guo, J.1
Kim, D.2
Gao, J.3
-
7
-
-
33645217264
-
Identification of proangiogenic genes and pathways by high-throughput functional genomics: TBK1 and the IRF3 pathway
-
Korherr C, GilleH, Schafer R, et al. Identification of proangiogenic genes and pathways by high-throughput functional genomics: TBK1 and the IRF3 pathway. Proc Natl Acad Sci USA 2006;103:4240-5
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 4240-4245
-
-
Korherr, C.1
Gille, H.2
Schafer, R.3
-
8
-
-
33749165933
-
RalB GTPase-mediated activation of the IkappaB family kinase TBK1 couples innate immune signaling to tumor cell survival
-
Chien Y, Kim S, Bumeister R, et al. RalB GTPase-mediated activation of the IkappaB family kinase TBK1 couples innate immune signaling to tumor cell survival. Cell 2006;127:157-70
-
(2006)
Cell
, vol.127
, pp. 157-170
-
-
Chien, Y.1
Kim, S.2
Bumeister, R.3
-
9
-
-
70449091786
-
Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1
-
Barbie DA, Tamayo P, Boehm JS, et al. Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1. Nature 2009;462:108-12
-
(2009)
Nature
, vol.462
, pp. 108-112
-
-
Barbie, D.A.1
Tamayo, P.2
Boehm, J.S.3
-
10
-
-
79951494608
-
TBK1 directly engages Akt/PKB survival signaling to support oncogenic transformation
-
Ou YH, Torres M, Ram R, et al. TBK1 directly engages Akt/PKB survival signaling to support oncogenic transformation. Mol Cell 2011;41:458-70
-
(2011)
Mol Cell
, vol.41
, pp. 458-470
-
-
Ou, Y.H.1
Torres, M.2
Ram, R.3
-
11
-
-
79955615939
-
IkappaB kinase epsilon and TANK-binding kinase 1 activate AKT by direct phosphorylation
-
Xie X, Zhang D, Zhao B, et al. IkappaB kinase epsilon and TANK-binding kinase 1 activate AKT by direct phosphorylation. Proc Natl Acad Sci USA 2011;108:6474-9
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 6474-6479
-
-
Xie, X.1
Zhang, D.2
Zhao, B.3
-
12
-
-
84870527124
-
TBK1 kinase addiction in lung cancer cells is mediated via autophagy of Tax1bp1/Ndp52 and non-canonical NF-kappaB signalling
-
Newman AC, Scholefield CL, Kemp AJ, et al. TBK1 kinase addiction in lung cancer cells is mediated via autophagy of Tax1bp1/Ndp52 and non-canonical NF-kappaB signalling. PLoS ONE 2012;7:e50672
-
(2012)
PLoS ONE
, vol.7
-
-
Newman, A.C.1
Scholefield, C.L.2
Kemp, A.J.3
-
13
-
-
84880653259
-
Dissection of TBK1 signaling via phosphoproteomics in lung cancer cells
-
Kim JY, Welsh EA, Oguz U, et al. Dissection of TBK1 signaling via phosphoproteomics in lung cancer cells. Proc Natl Acad Sci USA 2013;110:12414-19
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, pp. 12414-12419
-
-
Kim, J.Y.1
Welsh, E.A.2
Oguz, U.3
-
14
-
-
70449109147
-
Requirement for NF-kappaB signalling in a mouse model of lung adenocarcinoma
-
Meylan E, Dooley AL, Feldser DM, et al. Requirement for NF-kappaB signalling in a mouse model of lung adenocarcinoma. Nature 2009;462:104-7
-
(2009)
Nature
, vol.462
, pp. 104-107
-
-
Meylan, E.1
Dooley, A.L.2
Feldser, D.M.3
-
15
-
-
84862778064
-
Reduced cell proliferation by IKK2 depletion in a mouse lung-cancer model
-
Xia Y, Yeddula N, Leblanc M, et al. Reduced cell proliferation by IKK2 depletion in a mouse lung-cancer model. Nat Cell Biol 2012;14:257-65
-
(2012)
Nat Cell Biol
, vol.14
, pp. 257-265
-
-
Xia, Y.1
Yeddula, N.2
Leblanc, M.3
-
16
-
-
84878602787
-
Lung tumor NF-kappaB signaling promotes T cell-mediated immune surveillance
-
Hopewell EL, Zhao W, Fulp WJ, et al. Lung tumor NF-kappaB signaling promotes T cell-mediated immune surveillance. J Clin Invest 2013;123:2509-22
-
(2013)
J Clin Invest
, vol.123
, pp. 2509-2522
-
-
Hopewell, E.L.1
Zhao, W.2
Fulp, W.J.3
-
17
-
-
67649823926
-
Use of the pharmacological inhibitor BX795 to study the regulation and physiological roles of TBK1 and IkappaB kinase epsilon: A distinct upstream kinase mediates Ser-172 phosphorylation and activation
-
Clark K, Plater L, Peggie M, Cohen P.Use of the pharmacological inhibitor BX795 to study the regulation and physiological roles of TBK1 and IkappaB kinase epsilon: a distinct upstream kinase mediates Ser-172 phosphorylation and activation. J Biol Chem 2009;284:14136-46
-
(2009)
J Biol Chem
, vol.284
, pp. 14136-14146
-
-
Clark, K.1
Plater, L.2
Peggie, M.3
Cohen, P.4
-
18
-
-
84873111794
-
Type i interferon response and innate immune sensing of cancer
-
Fuertes MB, Woo SR, Burnett B, et al. Type I interferon response and innate immune sensing of cancer. Trends Immunol 2013;34:67-73
-
(2013)
Trends Immunol
, vol.34
, pp. 67-73
-
-
Fuertes, M.B.1
Woo, S.R.2
Burnett, B.3
-
19
-
-
3242664636
-
Recognition of commensal microflora by toll-like receptors is required for intestinal homeostasis
-
Rakoff-Nahoum S, Paglino J, Eslami-Varzaneh F, et al. Recognition of commensal microflora by toll-like receptors is required for intestinal homeostasis. Cell 2004;118:229-41
-
(2004)
Cell
, vol.118
, pp. 229-241
-
-
Rakoff-Nahoum, S.1
Paglino, J.2
Eslami-Varzaneh, F.3
-
20
-
-
84887212416
-
Intestinal epithelial-derived TAK1 signaling is essential for cytoprotection against chemical-induced colitis
-
Kim JY, Kajino-Sakamoto R, Omori E, et al. Intestinal epithelial-derived TAK1 signaling is essential for cytoprotection against chemical-induced colitis. PLoS One 2009;4:e4561
-
(2009)
PLoS One
, vol.4
-
-
Kim, J.Y.1
Kajino-Sakamoto, R.2
Omori, E.3
-
21
-
-
58149186087
-
Establishment of patient-derived non-small cell lung cancer xenografts as models for the identification of predictive biomarkers
-
Fichtner I, Rolff J, Soong R, et al. Establishment of patient-derived non-small cell lung cancer xenografts as models for the identification of predictive biomarkers. Clin Cancer Res 2008;14:6456-68
-
(2008)
Clin Cancer Res
, vol.14
, pp. 6456-6468
-
-
Fichtner, I.1
Rolff, J.2
Soong, R.3
|